IMP: Integrative Multi-species Prediction

Homo sapiens

37 genes annotated in human

Multi-species View

peptidyl lysine methylation

GO:0018022

The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "peptidyl lysine methylation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "peptidyl lysine methylation" (in gray)

Name	Description	Probability	Func Analog Organism
WDR5	WD repeat domain 5	1.000
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.997
RBBP5	retinoblastoma binding protein 5	0.995
CBX5	chromobox homolog 5	0.994	Fly
HIST1H3B	histone cluster 1, H3b	0.978
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.951
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.889
CBX1	chromobox homolog 1	0.876	Fly
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.874
NCOA6	nuclear receptor coactivator 6	0.854
MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	0.742
PAXIP1	PAX interacting (with transcription-activation domain) protein 1	0.742
POGZ	pogo transposable element with ZNF domain	0.739
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.716
H3F3C	H3 histone, family 3C	0.604
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.578
CBX3	chromobox homolog 3	0.489	Fly
LBR	lamin B receptor	0.479
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.474
MYST1	MYST histone acetyltransferase 1	0.432
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.419
MEN1	multiple endocrine neoplasia I	0.402
SETD1A	SET domain containing 1A	0.393
TWIST1	twist homolog 1 (Drosophila)	0.349
HCFC1	host cell factor C1 (VP16-accessory protein)	0.344
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.314	Mouse
MBD1	methyl-CpG binding domain protein 1	0.251
RSBN1	round spermatid basic protein 1	0.235
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.222
INCENP	inner centromere protein antigens 135/155kDa	0.205
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.200
CHD8	chromodomain helicase DNA binding protein 8	0.187
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.184	Mouse
ADSS	adenylosuccinate synthase	0.176
FAM20C	family with sequence similarity 20, member C	0.148
ADNP	activity-dependent neuroprotector homeobox	0.143
WDR61	WD repeat domain 61	0.130
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.126
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.121
NIPBL	Nipped-B homolog (Drosophila)	0.116
PRRC2B	proline-rich coiled-coil 2B	0.115
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.114
MPHOSPH8	M-phase phosphoprotein 8	0.113
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.109
KDM6A	lysine (K)-specific demethylase 6A	0.100
TCEA1	transcription elongation factor A (SII), 1	0.097
TSC22D1	TSC22 domain family, member 1	0.084
DPY30	dpy-30 homolog (C. elegans)	0.081
USP47	ubiquitin specific peptidase 47	0.081
ANKRD12	ankyrin repeat domain 12	0.076
CUL4A	cullin 4A	0.072
NSL1	NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.071
KDM1A	lysine (K)-specific demethylase 1A	0.071
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.070
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.068
RBM5	RNA binding motif protein 5	0.063
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.057
AFF1	AF4/FMR2 family, member 1	0.052
PIAS1	protein inhibitor of activated STAT, 1	0.046
RLF	rearranged L-myc fusion	0.046
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.046
TOP2B	topoisomerase (DNA) II beta 180kDa	0.044
SUV39H2	suppressor of variegation 3-9 homolog 2 (Drosophila)	0.043
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.043
ZNF292	zinc finger protein 292	0.043
HCFC2	host cell factor C2	0.042
ATN1	atrophin 1	0.041
H2AFV	H2A histone family, member V	0.041
C1orf63	chromosome 1 open reading frame 63	0.037
RBM4B	RNA binding motif protein 4B	0.035
SERTAD1	SERTA domain containing 1	0.033
CXXC1	CXXC finger protein 1	0.032
KDM2A	lysine (K)-specific demethylase 2A	0.031
KDM5A	lysine (K)-specific demethylase 5A	0.031
CLK4	CDC-like kinase 4	0.029
WAC	WW domain containing adaptor with coiled-coil	0.028
JMJD1C	jumonji domain containing 1C	0.028
RABGAP1	RAB GTPase activating protein 1	0.028
ZFC3H1	zinc finger, C3H1-type containing	0.027
C16orf53	chromosome 16 open reading frame 53	0.027
VEZF1	vascular endothelial zinc finger 1	0.027
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.027	Human Fly
YTHDC1	YTH domain containing 1	0.026
SOCS1	suppressor of cytokine signaling 1	0.025
RSF1	remodeling and spacing factor 1	0.025
WIZ	widely interspaced zinc finger motifs	0.025
C10orf12	chromosome 10 open reading frame 12	0.025
H3F3B	H3 histone, family 3B (H3.3B)	0.024
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.024
LRIF1	ligand dependent nuclear receptor interacting factor 1	0.023
MBIP	MAP3K12 binding inhibitory protein 1	0.023
KLF12	Kruppel-like factor 12	0.022
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.022
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.021
PRKCZ	protein kinase C, zeta	0.021
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.021
ATAD2B	ATPase family, AAA domain containing 2B	0.020
CREBZF	CREB/ATF bZIP transcription factor	0.020
ZNF512B	zinc finger protein 512B	0.020
KDM3B	lysine (K)-specific demethylase 3B	0.020
WDR82	WD repeat domain 82	0.019
PASK	PAS domain containing serine/threonine kinase	0.019
ADNP2	ADNP homeobox 2	0.018
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.018
WDR48	WD repeat domain 48	0.018
EHMT1	euchromatic histone-lysine N-methyltransferase 1	0.018
EPC2	enhancer of polycomb homolog 2 (Drosophila)	0.018
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.018
MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)	0.018
DAXX	death-domain associated protein	0.017
ANKHD1-EIF4EBP3	ANKHD1-EIF4EBP3 readthrough	0.017
C5orf41	chromosome 5 open reading frame 41	0.017
FAM13B	family with sequence similarity 13, member B	0.017
OSGEP	O-sialoglycoprotein endopeptidase	0.016
PRMT6	protein arginine methyltransferase 6	0.016
KIAA1370	KIAA1370	0.016
PHF19	PHD finger protein 19	0.016
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.016
C12orf41	chromosome 12 open reading frame 41	0.015
PBRM1	polybromo 1	0.015
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.014
ZNF12	zinc finger protein 12	0.014
L3MBTL1	l(3)mbt-like 1 (Drosophila)	0.014
EED	embryonic ectoderm development	0.014	Fly
SGOL1	shugoshin-like 1 (S. pombe)	0.014
CCNL1	cyclin L1	0.013
KIAA0430	KIAA0430	0.013
XAGE2	X antigen family, member 2	0.013
ZC3H11A	zinc finger CCCH-type containing 11A	0.013
ZNF828	zinc finger protein 828	0.013
KLHL24	kelch-like 24 (Drosophila)	0.013
GOLGB1	golgin B1	0.013
NCOA2	nuclear receptor coactivator 2	0.013
PIKFYVE	phosphoinositide kinase, FYVE finger containing	0.013
SECISBP2	SECIS binding protein 2	0.012
FBXW11	F-box and WD repeat domain containing 11	0.012
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.012
MRFAP1	Morf4 family associated protein 1	0.012
GGNBP2	gametogenetin binding protein 2	0.012
PUM1	pumilio homolog 1 (Drosophila)	0.012
VPS4B	vacuolar protein sorting 4 homolog B (S. cerevisiae)	0.012
ZBTB44	zinc finger and BTB domain containing 44	0.012
TBCE	tubulin folding cofactor E	0.012
USP24	ubiquitin specific peptidase 24	0.012
PURA	purine-rich element binding protein A	0.012
CEP350	centrosomal protein 350kDa	0.012
ERCC5	excision repair cross-complementing rodent repair deficiency, complementation group 5	0.012
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.012
CCNG2	cyclin G2	0.011
MSL2	male-specific lethal 2 homolog (Drosophila)	0.011
PRR14	proline rich 14	0.011
HELZ	helicase with zinc finger	0.011
HIST3H3	histone cluster 3, H3	0.011
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.011
SIRT6	sirtuin 6	0.011
HIST1H3A	histone cluster 1, H3a	0.011
RCOR3	REST corepressor 3	0.011
CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	0.011
FAM126B	family with sequence similarity 126, member B	0.011
PHF20L1	PHD finger protein 20-like 1	0.011
PCF11	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	0.011
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.011
MXI1	MAX interactor 1	0.010
AKAP11	A kinase (PRKA) anchor protein 11	0.010
ZNF24	zinc finger protein 24	0.010
KLHDC4	kelch domain containing 4	0.010
MYST2	MYST histone acetyltransferase 2	0.010
SETMAR	SET domain and mariner transposase fusion gene	0.010
LNX1	ligand of numb-protein X 1	0.010
OGDHL	oxoglutarate dehydrogenase-like	0.010
BTBD7	BTB (POZ) domain containing 7	0.010
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.010
WDR19	WD repeat domain 19	0.010