IMP: Integrative Multi-species Prediction

Homo sapiens

19 genes annotated in human

Multi-species View

protein localization to endoplasmic reticulum

GO:0070972

A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein localization to endoplasmic reticulum"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein localization to endoplasmic reticulum" (in gray)

Name	Description	Probability	Func Analog Organism
HSPA1A	heat shock 70kDa protein 1A	0.943	Yeast
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.931
HSPA1B	heat shock 70kDa protein 1B	0.894	Yeast
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.791
CANX	calnexin	0.774
SURF4	surfeit 4	0.452
BAG1	BCL2-associated athanogene	0.399
BAG3	BCL2-associated athanogene 3	0.369
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.351
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.337
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.332
LAPTM5	lysosomal protein transmembrane 5	0.267
TMEM173	transmembrane protein 173	0.229
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.213
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.210
PEX19	peroxisomal biogenesis factor 19	0.207
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.195
BAG6	BCL2-associated athanogene 6	0.187
LMAN1	lectin, mannose-binding, 1	0.173
SPTB	spectrin, beta, erythrocytic	0.169
SEC61B	Sec61 beta subunit	0.150
VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	0.142
RSL24D1	ribosomal L24 domain containing 1	0.122
PPID	peptidylprolyl isomerase D	0.121
DERL1	Der1-like domain family, member 1	0.121
SSR1	signal sequence receptor, alpha	0.111
PEX13	peroxisomal biogenesis factor 13	0.107
HSPH1	heat shock 105kDa/110kDa protein 1	0.104
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.096
RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	0.093
CREB3	cAMP responsive element binding protein 3	0.090
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.090
OCRL	oculocerebrorenal syndrome of Lowe	0.089
RABIF	RAB interacting factor	0.086
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.085
SEC63	SEC63 homolog (S. cerevisiae)	0.081
RPN1	ribophorin I	0.077
NACA	nascent polypeptide-associated complex alpha subunit	0.073
ATF7IP	activating transcription factor 7 interacting protein	0.068
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.064
EHD1	EH-domain containing 1	0.063
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.061
VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	0.058	Human
RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	0.057
UBQLN4	ubiquilin 4	0.057
UBL4A	ubiquitin-like 4A	0.056
PPP6C	protein phosphatase 6, catalytic subunit	0.055
SAV1	salvador homolog 1 (Drosophila)	0.054
PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	0.054
USP54	ubiquitin specific peptidase 54	0.054
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.050
OSBPL9	oxysterol binding protein-like 9	0.050
RPL36AL	ribosomal protein L36a-like	0.050
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.046
RAI2	retinoic acid induced 2	0.045
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.044
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.044
PDCD6	programmed cell death 6	0.043
BAG2	BCL2-associated athanogene 2	0.041
SERP1	stress-associated endoplasmic reticulum protein 1	0.040
SEL1L	sel-1 suppressor of lin-12-like (C. elegans)	0.040
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.040
SH3GL2	SH3-domain GRB2-like 2	0.038
RAB8A	RAB8A, member RAS oncogene family	0.036	Human
ERBB2IP	erbb2 interacting protein	0.036
AKAP6	A kinase (PRKA) anchor protein 6	0.034
SEC62	SEC62 homolog (S. cerevisiae)	0.034
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.032
ARL1	ADP-ribosylation factor-like 1	0.032
GDI2	GDP dissociation inhibitor 2	0.031
CDK17	cyclin-dependent kinase 17	0.031
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.031
EPS15	epidermal growth factor receptor pathway substrate 15	0.031
CNBP	CCHC-type zinc finger, nucleic acid binding protein	0.030
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.029
USP8	ubiquitin specific peptidase 8	0.027
UTP14C	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)	0.027
GFPT1	glutamine--fructose-6-phosphate transaminase 1	0.026
TBK1	TANK-binding kinase 1	0.026
USO1	USO1 vesicle docking protein homolog (yeast)	0.025
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.025
LAMP1	lysosomal-associated membrane protein 1	0.025
DPP8	dipeptidyl-peptidase 8	0.025
SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1	0.025
FIS1	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	0.024
SMAD2	SMAD family member 2	0.024
SEPT7	septin 7	0.023
MORF4L1	mortality factor 4 like 1	0.022
TMED9	transmembrane emp24 protein transport domain containing 9	0.021
MEOX2	mesenchyme homeobox 2	0.021
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.021
RPN2	ribophorin II	0.021
HYOU1	hypoxia up-regulated 1	0.020
STX5	syntaxin 5	0.020
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.019
ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)	0.019
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.018
PEX14	peroxisomal biogenesis factor 14	0.018
ANTXR2	anthrax toxin receptor 2	0.018
PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	0.018
TSG101	tumor susceptibility gene 101	0.018
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.017
DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	0.016
TMEM41B	transmembrane protein 41B	0.016
MAPK8	mitogen-activated protein kinase 8	0.016
TRADD	TNFRSF1A-associated via death domain	0.016
MCFD2	multiple coagulation factor deficiency 2	0.016
CSNK1A1	casein kinase 1, alpha 1	0.016
PEX11B	peroxisomal biogenesis factor 11 beta	0.016
TRAM1	translocation associated membrane protein 1	0.016
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.016
SLC35B1	solute carrier family 35, member B1	0.016
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.015
TTC1	tetratricopeptide repeat domain 1	0.015
C19orf10	chromosome 19 open reading frame 10	0.015
USP47	ubiquitin specific peptidase 47	0.015
SDF4	stromal cell derived factor 4	0.014
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.014
RAB10	RAB10, member RAS oncogene family	0.014
YIPF6	Yip1 domain family, member 6	0.014
BCL2L12	BCL2-like 12 (proline rich)	0.014
ANKRD28	ankyrin repeat domain 28	0.014
CHMP1B	chromatin modifying protein 1B	0.014
NUCB2	nucleobindin 2	0.014
GRAP2	GRB2-related adaptor protein 2	0.014
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.013
KIF5B	kinesin family member 5B	0.013
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.013
HSPA1L	heat shock 70kDa protein 1-like	0.013	Yeast
HSPA2	heat shock 70kDa protein 2	0.013	Yeast
GNPDA2	glucosamine-6-phosphate deaminase 2	0.013
YIPF5	Yip1 domain family, member 5	0.013
TTC3	tetratricopeptide repeat domain 3	0.012
FKBP2	FK506 binding protein 2, 13kDa	0.012
ARCN1	archain 1	0.012
CTSD	cathepsin D	0.012
RHAG	Rh-associated glycoprotein	0.012
OXSR1	oxidative-stress responsive 1	0.012
CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	0.012
DSTN	destrin (actin depolymerizing factor)	0.012
ZFYVE9	zinc finger, FYVE domain containing 9	0.012
CCDC47	coiled-coil domain containing 47	0.012
HSPA13	heat shock protein 70kDa family, member 13	0.012
GOLGB1	golgin B1	0.012
UFM1	ubiquitin-fold modifier 1	0.012
STK3	serine/threonine kinase 3	0.011
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.011
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.011
OGFOD2	2-oxoglutarate and iron-dependent oxygenase domain containing 2	0.011
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.011
TBC1D15	TBC1 domain family, member 15	0.011
DCTN6	dynactin 6	0.011
CTNNBL1	catenin, beta like 1	0.011
TMBIM6	transmembrane BAX inhibitor motif containing 6	0.011
STARD3NL	STARD3 N-terminal like	0.011
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.011
SELT	selenoprotein T	0.011
SIL1	SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)	0.011
SLC39A6	solute carrier family 39 (zinc transporter), member 6	0.011
AICDA	activation-induced cytidine deaminase	0.011
BAG4	BCL2-associated athanogene 4	0.011
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.010
FAM177A1	family with sequence similarity 177, member A1	0.010
TROVE2	TROVE domain family, member 2	0.010
C4orf14	chromosome 4 open reading frame 14	0.010
DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	0.010
EGLN3	egl nine homolog 3 (C. elegans)	0.010