IMP: Integrative Multi-species Prediction

Homo sapiens

37 genes annotated in human

sexual reproduction

GO:0019953

A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sexual reproduction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "sexual reproduction" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.650	Yeast Worm Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.489	Yeast Fly
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.403
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.359	Yeast Worm Fly
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.350	Worm Fly
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.273	Rat
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.204
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.178	Mouse Worm Fly
CREBBP	CREB binding protein	0.154	Worm
EGFR	epidermal growth factor receptor	0.145	Worm Fly
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.144	Worm Fly
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.143	Worm
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.132
CSNK2B	casein kinase 2, beta polypeptide	0.132	Worm
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.129
HDAC1	histone deacetylase 1	0.120
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.110	Worm
RHOA	ras homolog gene family, member A	0.106	Worm Fly
ATXN1	ataxin 1	0.095
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.094
SMAD3	SMAD family member 3	0.094
BRCA1	breast cancer 1, early onset	0.086
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.085	Fly
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.084
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	0.084
UBC	ubiquitin C	0.084	Fly
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	0.076	Fly
EP300	E1A binding protein p300	0.076	Worm
PABPC1	poly(A) binding protein, cytoplasmic 1	0.075	Worm
TARDBP	TAR DNA binding protein	0.070
APC	adenomatous polyposis coli	0.069	Fly
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.066
SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	0.062	Worm
SNRPE	small nuclear ribonucleoprotein polypeptide E	0.061	Worm
ESR1	estrogen receptor 1	0.060
SKP2	S-phase kinase-associated protein 2 (p45)	0.060
NCL	nucleolin	0.060
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.059	Fly
FGFR1	fibroblast growth factor receptor 1	0.059	Fly
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.057
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.056	Fly
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.055
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.055	Fly
SP1	Sp1 transcription factor	0.055
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.054	Mouse
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.054	Mouse
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.053	Yeast Fly
XIAP	X-linked inhibitor of apoptosis	0.052
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.051
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.051	Mouse Fly
SIRT1	sirtuin 1	0.051	Mouse
MPRIP	myosin phosphatase Rho interacting protein	0.051
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.050
PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)	0.049
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.049	Fly
CDK2	cyclin-dependent kinase 2	0.048
CKAP5	cytoskeleton associated protein 5	0.047	Worm Fly
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.047
QKI	quaking homolog, KH domain RNA binding (mouse)	0.046	Mouse Worm Fly
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.046	Yeast
TCP1	t-complex 1	0.045	Mouse
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.045
SSB	Sjogren syndrome antigen B (autoantigen La)	0.045
NCOR2	nuclear receptor corepressor 2	0.045
BRCA2	breast cancer 2, early onset	0.044	Mouse
RBM39	RNA binding motif protein 39	0.044
GSK3B	glycogen synthase kinase 3 beta	0.044	Worm Fly
SNX9	sorting nexin 9	0.043
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.043	Fly
SFN	stratifin	0.043	Yeast Fly
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.043
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.041	Worm Fly
SNRPG	small nuclear ribonucleoprotein polypeptide G	0.041
LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.041
CBX5	chromobox homolog 5	0.041	Worm
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.039	Mouse
SERBP1	SERPINE1 mRNA binding protein 1	0.039
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.039	Worm Fly
EIF4A3	eukaryotic translation initiation factor 4A3	0.038	Worm Fly
MCM7	minichromosome maintenance complex component 7	0.038
HDAC2	histone deacetylase 2	0.037
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.037	Fly
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.037	Mouse Fly
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.037	Yeast Worm Fly
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.036	Fly
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.036	Worm
ILF3	interleukin enhancer binding factor 3, 90kDa	0.036
PTBP1	polypyrimidine tract binding protein 1	0.036	Zebrafish Fly
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.036	Worm Fly
CCNB1	cyclin B1	0.036	Rat Worm
HMGA1	high mobility group AT-hook 1	0.035	Mouse
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.035
YBX1	Y box binding protein 1	0.035
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.035	Worm Fly
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.035
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.034	Worm Fly
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.034	Worm
NOTCH1	notch 1	0.034	Rat Fly
STIP1	stress-induced-phosphoprotein 1	0.034
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.034	Fly
FYN	FYN oncogene related to SRC, FGR, YES	0.033	Fly
FLNA	filamin A, alpha	0.033	Worm Fly
NAP1L1	nucleosome assembly protein 1-like 1	0.032
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.032	Yeast Worm Fly
C1QBP	complement component 1, q subcomponent binding protein	0.032
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.032
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.031	Worm
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.031	Yeast
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.030	Fly
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.029	Fly
CTNNBL1	catenin, beta like 1	0.029
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.029	Fly
RAN	RAN, member RAS oncogene family	0.028	Worm
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.028
SRSF2	serine/arginine-rich splicing factor 2	0.028
NCOA6	nuclear receptor coactivator 6	0.028
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.028
HSPA4	heat shock 70kDa protein 4	0.027
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.027	Worm Fly
CAND1	cullin-associated and neddylation-dissociated 1	0.027
SMAD2	SMAD family member 2	0.027	Zebrafish
CUL1	cullin 1	0.027
ATF2	activating transcription factor 2	0.027
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.027	Worm Fly
PRMT5	protein arginine methyltransferase 5	0.027	Fly
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.027
KIF23	kinesin family member 23	0.026	Worm
LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.026
INSR	insulin receptor	0.026	Worm Fly
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.026
FEN1	flap structure-specific endonuclease 1	0.026
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.025	Worm Fly
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.025
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.025
PBK	PDZ binding kinase	0.025
WIPF1	WAS/WASL interacting protein family, member 1	0.025
MAPK8	mitogen-activated protein kinase 8	0.025	Yeast Fly
SRSF9	serine/arginine-rich splicing factor 9	0.025
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.025	Worm
SRRM1	serine/arginine repetitive matrix 1	0.024
TP53	tumor protein p53	0.024	Zebrafish Fly
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.024	Worm
PGR	progesterone receptor	0.024	Mouse Rat
HDAC3	histone deacetylase 3	0.024
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.024	Yeast Worm Fly
EED	embryonic ectoderm development	0.024
MAPK1	mitogen-activated protein kinase 1	0.024	Yeast Worm
BTRC	beta-transducin repeat containing	0.024	Fly
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.024
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.024
CSNK1E	casein kinase 1, epsilon	0.024
SRPK2	SRSF protein kinase 2	0.024	Worm Fly
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.024
NOP56	NOP56 ribonucleoprotein homolog (yeast)	0.024
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.023
RACGAP1	Rac GTPase activating protein 1	0.023
ARF4	ADP-ribosylation factor 4	0.023	Worm
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.023
CCT2	chaperonin containing TCP1, subunit 2 (beta)	0.023	Mouse
NONO	non-POU domain containing, octamer-binding	0.023	Fly
TFDP1	transcription factor Dp-1	0.023	Fly
NCOR1	nuclear receptor corepressor 1	0.023
PBX1	pre-B-cell leukemia homeobox 1	0.023
SNW1	SNW domain containing 1	0.023	Worm
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.023
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.022	Worm Fly
GTPBP4	GTP binding protein 4	0.022
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.022
SRSF1	serine/arginine-rich splicing factor 1	0.022
EIF4A1	eukaryotic translation initiation factor 4A1	0.022	Fly
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.022
SF3B4	splicing factor 3b, subunit 4, 49kDa	0.022
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.022	Worm Fly
PRKCZ	protein kinase C, zeta	0.022
SRSF10	serine/arginine-rich splicing factor 10	0.022
JUN	jun proto-oncogene	0.022	Fly
SNAP25	synaptosomal-associated protein, 25kDa	0.022
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.021	Fly
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.021
RPA1	replication protein A1, 70kDa	0.021
SSRP1	structure specific recognition protein 1	0.021	Worm
ZYX	zyxin	0.021
EIF4B	eukaryotic translation initiation factor 4B	0.021
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.021
DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	0.021
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.021
PTBP2	polypyrimidine tract binding protein 2	0.021	Fly
CAPRIN1	cell cycle associated protein 1	0.020
JUNB	jun B proto-oncogene	0.020	Fly
AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	0.020
PDPK1	3-phosphoinositide dependent protein kinase-1	0.020
FBL	fibrillarin	0.020
BTF3	basic transcription factor 3	0.020
MED10	mediator complex subunit 10	0.020
STRN3	striatin, calmodulin binding protein 3	0.020
BCL2L1	BCL2-like 1	0.020	Mouse
OCRL	oculocerebrorenal syndrome of Lowe	0.020
PTEN	phosphatase and tensin homolog	0.019	Mouse
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.019	Worm
IQGAP1	IQ motif containing GTPase activating protein 1	0.019
ANAPC5	anaphase promoting complex subunit 5	0.019
GRB2	growth factor receptor-bound protein 2	0.019
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.019
SFPQ	splicing factor proline/glutamine-rich	0.019	Fly
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.019
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.019
TGFB1	transforming growth factor, beta 1	0.019	Mouse
RANBP2	RAN binding protein 2	0.019
SRPK1	SRSF protein kinase 1	0.019	Worm Fly
AATF	apoptosis antagonizing transcription factor	0.019
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.019
CCNB2	cyclin B2	0.018	Worm
SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	0.018	Worm
MEN1	multiple endocrine neoplasia I	0.018
UBXN7	UBX domain protein 7	0.018
EIF3K	eukaryotic translation initiation factor 3, subunit K	0.018
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.018
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.018
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.018
JAG1	jagged 1	0.018	Human
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.018	Worm
MYH9	myosin, heavy chain 9, non-muscle	0.018	Fly
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.018	Mouse Worm Fly
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.017	Fly
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.017
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.017
FN1	fibronectin 1	0.017
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.017	Fly
IRS1	insulin receptor substrate 1	0.017	Fly
LSM6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.017
CKS2	CDC28 protein kinase regulatory subunit 2	0.017
VHL	von Hippel-Lindau tumor suppressor	0.017
LRRK2	leucine-rich repeat kinase 2	0.017
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.017
USP42	ubiquitin specific peptidase 42	0.017
RPL6	ribosomal protein L6	0.017
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.017	Mouse
E2F4	E2F transcription factor 4, p107/p130-binding	0.017	Fly
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.017	Worm
EIF5B	eukaryotic translation initiation factor 5B	0.017
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.017
NOP58	NOP58 ribonucleoprotein homolog (yeast)	0.017
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.017	Worm Fly
PRPF31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)	0.017	Worm
WDR77	WD repeat domain 77	0.017	Fly
NUP98	nucleoporin 98kDa	0.017	Worm
CUL3	cullin 3	0.017	Worm
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.017
MSH6	mutS homolog 6 (E. coli)	0.017
SRSF3	serine/arginine-rich splicing factor 3	0.016	Worm
GRB10	growth factor receptor-bound protein 10	0.016
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.016	Worm Fly
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.016	Worm Fly
TNRC6A	trinucleotide repeat containing 6A	0.016
MKI67	antigen identified by monoclonal antibody Ki-67	0.016
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.016
BMP2	bone morphogenetic protein 2	0.016	Fly
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.016
EBNA1BP2	EBNA1 binding protein 2	0.016
TRIM37	tripartite motif containing 37	0.016
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.016
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.016	Fly
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.016
CCNA2	cyclin A2	0.016
GEMIN5	gem (nuclear organelle) associated protein 5	0.016
IGF1R	insulin-like growth factor 1 receptor	0.016	Zebrafish Worm Fly
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.016	Mouse
SON	SON DNA binding protein	0.016
GAR1	GAR1 ribonucleoprotein homolog (yeast)	0.016
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.016
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.016
PICALM	phosphatidylinositol binding clathrin assembly protein	0.016
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.015	Yeast
CDK1	cyclin-dependent kinase 1	0.015	Worm Fly
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.015
SKP1	S-phase kinase-associated protein 1	0.015
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.015	Fly
ANAPC1	anaphase promoting complex subunit 1	0.015
CNOT7	CCR4-NOT transcription complex, subunit 7	0.015
RB1	retinoblastoma 1	0.015
ADAM15	ADAM metallopeptidase domain 15	0.015
HSPA8	heat shock 70kDa protein 8	0.015
ANXA5	annexin A5	0.015	Worm
RIPK2	receptor-interacting serine-threonine kinase 2	0.015
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.015
NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.015
PA2G4	proliferation-associated 2G4, 38kDa	0.015
TRA2B	transformer 2 beta homolog (Drosophila)	0.015
SYK	spleen tyrosine kinase	0.015	Fly
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.015
MED28	mediator complex subunit 28	0.015
METTL1	methyltransferase like 1	0.015
ARHGAP1	Rho GTPase activating protein 1	0.015
SEPT2	septin 2	0.015	Yeast
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.015
TRIM28	tripartite motif containing 28	0.015
ILF2	interleukin enhancer binding factor 2, 45kDa	0.015
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.015
PPP4C	protein phosphatase 4, catalytic subunit	0.015
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.015	Fly
RBPMS	RNA binding protein with multiple splicing	0.015
ARIH2	ariadne homolog 2 (Drosophila)	0.015
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.015	Yeast Worm Fly
SRSF6	serine/arginine-rich splicing factor 6	0.014	Worm
SETD7	SET domain containing (lysine methyltransferase) 7	0.014
KAT2B	K(lysine) acetyltransferase 2B	0.014
NCK1	NCK adaptor protein 1	0.014
MYST1	MYST histone acetyltransferase 1	0.014
VRK1	vaccinia related kinase 1	0.014	Worm Fly
KLHL12	kelch-like 12 (Drosophila)	0.014
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.014
RAE1	RAE1 RNA export 1 homolog (S. pombe)	0.014	Fly
RPL4	ribosomal protein L4	0.014
YAP1	Yes-associated protein 1	0.014	Fly
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.014
PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.014
EGR1	early growth response 1	0.014	Worm
DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.014	Worm
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.014	Worm
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.014	Yeast Worm
STRN4	striatin, calmodulin binding protein 4	0.014
BMPR1A	bone morphogenetic protein receptor, type IA	0.014	Fly
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.014
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.014
LSM5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.014
CAV1	caveolin 1, caveolae protein, 22kDa	0.014
HSPH1	heat shock 105kDa/110kDa protein 1	0.014
ETF1	eukaryotic translation termination factor 1	0.014
WDR5	WD repeat domain 5	0.014
PNN	pinin, desmosome associated protein	0.014
MED6	mediator complex subunit 6	0.014	Worm
SEC24D	SEC24 family, member D (S. cerevisiae)	0.014
SMAD5	SMAD family member 5	0.014	Mouse Fly
SYNE1	spectrin repeat containing, nuclear envelope 1	0.014
EXOC7	exocyst complex component 7	0.014
NHP2L1	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	0.014
SNRPA1	small nuclear ribonucleoprotein polypeptide A'	0.014
DLG4	discs, large homolog 4 (Drosophila)	0.014	Worm Fly
AFF4	AF4/FMR2 family, member 4	0.014	Mouse
FKBP1A	FK506 binding protein 1A, 12kDa	0.014
TRIP6	thyroid hormone receptor interactor 6	0.014
HSF1	heat shock transcription factor 1	0.014	Mouse
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.014	Worm Fly
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.014
TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	0.014	Fly
CALU	calumenin	0.014
ERH	enhancer of rudimentary homolog (Drosophila)	0.013	Worm
MEIS1	Meis homeobox 1	0.013	Worm
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.013	Fly
BLNK	B-cell linker	0.013
DDX20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	0.013	Mouse
FANCG	Fanconi anemia, complementation group G	0.013
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.013	Mouse
CTPS	CTP synthase	0.013
RGS2	regulator of G-protein signaling 2, 24kDa	0.013	Mouse
MCM3	minichromosome maintenance complex component 3	0.013
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.013
E2F6	E2F transcription factor 6	0.013	Fly
MTA1	metastasis associated 1	0.013
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.013
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.013
FHL2	four and a half LIM domains 2	0.013
SMAD4	SMAD family member 4	0.013	Fly
WEE1	WEE1 homolog (S. pombe)	0.013
SPAG9	sperm associated antigen 9	0.013
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.013
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.013	Mouse
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.013
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.013
NUP153	nucleoporin 153kDa	0.013
SNIP1	Smad nuclear interacting protein 1	0.013
FGF1	fibroblast growth factor 1 (acidic)	0.013
IL1RAP	interleukin 1 receptor accessory protein	0.013
CUX1	cut-like homeobox 1	0.013	Fly
DKC1	dyskeratosis congenita 1, dyskerin	0.013
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.013	Fly
ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.013
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.013
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.013
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.013
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.013	Worm
APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.013
TSKS	testis-specific serine kinase substrate	0.013
RNPS1	RNA binding protein S1, serine-rich domain	0.013	Worm
SET	SET nuclear oncogene	0.013
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.013
SMAD7	SMAD family member 7	0.013
IL1B	interleukin 1, beta	0.013	Rat
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.013
NOTCH3	notch 3	0.013	Fly
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.013	Worm
CHERP	calcium homeostasis endoplasmic reticulum protein	0.013
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.013
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.013	Yeast
FKBP4	FK506 binding protein 4, 59kDa	0.013
MCMBP	minichromosome maintenance complex binding protein	0.013
PRDX1	peroxiredoxin 1	0.013
BRIX1	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	0.013	Worm
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.013
WDR3	WD repeat domain 3	0.013
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.012	Worm
PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	0.012
PARP1	poly (ADP-ribose) polymerase 1	0.012
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.012	Mouse Worm Fly
ACTN2	actinin, alpha 2	0.012
SMAD1	SMAD family member 1	0.012	Mouse Fly
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.012	Fly
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.012
PLK1	polo-like kinase 1	0.012	Worm Fly
MAPT	microtubule-associated protein tau	0.012
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.012	Worm Fly
MSH4	mutS homolog 4 (E. coli)	0.012
SF3A3	splicing factor 3a, subunit 3, 60kDa	0.012	Worm Fly
BUD13	BUD13 homolog (S. cerevisiae)	0.012
LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.012	Worm
DUSP1	dual specificity phosphatase 1	0.012
SEPT11	septin 11	0.012
PRC1	protein regulator of cytokinesis 1	0.012	Fly
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.012	Yeast Worm
MYCBP	c-myc binding protein	0.012
VCAM1	vascular cell adhesion molecule 1	0.012
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.012
XPO1	exportin 1 (CRM1 homolog, yeast)	0.012
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.012
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.012
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.012
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.012	Worm
RPL5	ribosomal protein L5	0.012
SH3BP2	SH3-domain binding protein 2	0.012
ARCN1	archain 1	0.012
RPS6	ribosomal protein S6	0.012	Mouse
NUDC	nuclear distribution gene C homolog (A. nidulans)	0.012	Worm
RNF126	ring finger protein 126	0.012
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.012	Worm
ANAPC4	anaphase promoting complex subunit 4	0.012
JAK2	Janus kinase 2	0.012	Fly
BTBD10	BTB (POZ) domain containing 10	0.012
AURKB	aurora kinase B	0.012	Fly
AHR	aryl hydrocarbon receptor	0.012	Fly
LAT	linker for activation of T cells	0.012
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.012	Mouse
RAB1A	RAB1A, member RAS oncogene family	0.012	Worm
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.012	Mouse Fly
SORBS3	sorbin and SH3 domain containing 3	0.012
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.012
MSN	moesin	0.012	Fly
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.012	Fly
DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	0.012
ADNP	activity-dependent neuroprotector homeobox	0.012
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.012
CLCN3	chloride channel 3	0.012
ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.012
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.012
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.012
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.012	Worm
PDCD6IP	programmed cell death 6 interacting protein	0.012
HMGB1	high mobility group box 1	0.012
HCFC1	host cell factor C1 (VP16-accessory protein)	0.012
BCL3	B-cell CLL/lymphoma 3	0.012	Fly
HARS	histidyl-tRNA synthetase	0.012	Worm
CD63	CD63 molecule	0.012
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.012	Mouse Fly
GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.012	Fly
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.012
RBM10	RNA binding motif protein 10	0.012
GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	0.012
WDYHV1	WDYHV motif containing 1	0.012
UBE2S	ubiquitin-conjugating enzyme E2S	0.012
MTF2	metal response element binding transcription factor 2	0.012
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.011
ATXN3	ataxin 3	0.011
TLK1	tousled-like kinase 1	0.011
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.011	Fly
CSNK1A1	casein kinase 1, alpha 1	0.011
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.011
PKM2	pyruvate kinase, muscle	0.011
ITGB4	integrin, beta 4	0.011	Fly
BMS1	BMS1 homolog, ribosome assembly protein (yeast)	0.011
CUL4B	cullin 4B	0.011	Fly
YKT6	YKT6 v-SNARE homolog (S. cerevisiae)	0.011
CDK7	cyclin-dependent kinase 7	0.011
TIMM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	0.011
UBA2	ubiquitin-like modifier activating enzyme 2	0.011
AURKA	aurora kinase A	0.011	Mouse
NCOA2	nuclear receptor coactivator 2	0.011	Rat
TOB1	transducer of ERBB2, 1	0.011
FBXO5	F-box protein 5	0.011	Mouse
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.011
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.011	Fly
MRPL3	mitochondrial ribosomal protein L3	0.011
EIF3M	eukaryotic translation initiation factor 3, subunit M	0.011	Fly
TRIO	triple functional domain (PTPRF interacting)	0.011
BARD1	BRCA1 associated RING domain 1	0.011	Rat
CD81	CD81 molecule	0.011	Human
DAZL	deleted in azoospermia-like	0.011	Mouse
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.011
GAS7	growth arrest-specific 7	0.011
THOC4	THO complex 4	0.011
BMP1	bone morphogenetic protein 1	0.011	Fly
CARM1	coactivator-associated arginine methyltransferase 1	0.011
BCOR	BCL6 corepressor	0.011
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.011
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.011	Mouse
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.011
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.011
NFYA	nuclear transcription factor Y, alpha	0.011
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.011
KLK10	kallikrein-related peptidase 10	0.011	Human
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.011
IL1R1	interleukin 1 receptor, type I	0.011	Rat
SIP1	survival of motor neuron protein interacting protein 1	0.011
TPM1	tropomyosin 1 (alpha)	0.011	Worm
E2F2	E2F transcription factor 2	0.011
VDAC1	voltage-dependent anion channel 1	0.011	Fly
GARS	glycyl-tRNA synthetase	0.011
TAL1	T-cell acute lymphocytic leukemia 1	0.011
POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	0.011
FSTL1	follistatin-like 1	0.011
ARID1A	AT rich interactive domain 1A (SWI-like)	0.011
KIF1B	kinesin family member 1B	0.011
MAPK6	mitogen-activated protein kinase 6	0.011
THBS1	thrombospondin 1	0.011
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.011
H2AFZ	H2A histone family, member Z	0.011
DNM1	dynamin 1	0.011	Fly
APLP2	amyloid beta (A4) precursor-like protein 2	0.011	Mouse
PML	promyelocytic leukemia	0.011
SF1	splicing factor 1	0.011	Worm
DGCR8	DiGeorge syndrome critical region gene 8	0.011	Fly
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.011	Worm
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.011
PRIM2	primase, DNA, polypeptide 2 (58kDa)	0.011
SNRPB2	small nuclear ribonucleoprotein polypeptide B	0.011	Worm Fly
SNX33	sorting nexin 33	0.011
RPS7	ribosomal protein S7	0.011
ZC3H15	zinc finger CCCH-type containing 15	0.011
SOX4	SRY (sex determining region Y)-box 4	0.011
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.011
SH3GL2	SH3-domain GRB2-like 2	0.011
MLF2	myeloid leukemia factor 2	0.011
CNOT8	CCR4-NOT transcription complex, subunit 8	0.011
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.011
PSEN1	presenilin 1	0.011
SCHIP1	schwannomin interacting protein 1	0.011
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.011	Fly
CDC7	cell division cycle 7 homolog (S. cerevisiae)	0.010
MAGEA2	melanoma antigen family A, 2	0.010
CDT1	chromatin licensing and DNA replication factor 1	0.010	Fly
ZHX1	zinc fingers and homeoboxes 1	0.010
FOXO1	forkhead box O1	0.010
XAB2	XPA binding protein 2	0.010
DLG1	discs, large homolog 1 (Drosophila)	0.010	Worm Fly
HIST1H3B	histone cluster 1, H3b	0.010	Yeast
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.010
EZR	ezrin	0.010	Fly
WASL	Wiskott-Aldrich syndrome-like	0.010	Fly
KDM4A	lysine (K)-specific demethylase 4A	0.010
NUP93	nucleoporin 93kDa	0.010
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.010	Mouse Fly
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.010	Worm Fly
EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	0.010
SRRT	serrate RNA effector molecule homolog (Arabidopsis)	0.010
WDR43	WD repeat domain 43	0.010	Worm
GAB1	GRB2-associated binding protein 1	0.010
FBLN1	fibulin 1	0.010
SUB1	SUB1 homolog (S. cerevisiae)	0.010
POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	0.010
ANLN	anillin, actin binding protein	0.010	Worm
DAZ1	deleted in azoospermia 1	0.010
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.010	Mouse Rat Fly
CANX	calnexin	0.010
RORA	RAR-related orphan receptor A	0.010
DCTN1	dynactin 1	0.010
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.010
MCRS1	microspherule protein 1	0.010
PLAUR	plasminogen activator, urokinase receptor	0.010
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.010
ZNF746	zinc finger protein 746	0.010
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.010
PHC2	polyhomeotic homolog 2 (Drosophila)	0.010	Mouse Fly
RAD23B	RAD23 homolog B (S. cerevisiae)	0.010	Mouse
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.010
PFN1	profilin 1	0.010
HSPA1B	heat shock 70kDa protein 1B	0.010
MYBBP1A	MYB binding protein (P160) 1a	0.010
CLTB	clathrin, light chain B	0.010
CCDC33	coiled-coil domain containing 33	0.010
HYOU1	hypoxia up-regulated 1	0.010
RPL13	ribosomal protein L13	0.010
EIF4A2	eukaryotic translation initiation factor 4A2	0.010	Fly
TRIP12	thyroid hormone receptor interactor 12	0.010
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.010
ADAM17	ADAM metallopeptidase domain 17	0.010
BARX1	BARX homeobox 1	0.010
MATR3	matrin 3	0.010
C14orf1	chromosome 14 open reading frame 1	0.010
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.010
STRAP	serine/threonine kinase receptor associated protein	0.010
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.010
JUP	junction plakoglobin	0.010	Worm Fly