IMP
Process View
reciprocal meiotic recombination
The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "reciprocal meiotic recombination"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| RPA1 | replication protein A1, 70kDa | 1.000 | Yeast | |
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.999 | Yeast | |
| RPA3 | replication protein A3, 14kDa | 0.963 | ||
| BRCA1 | breast cancer 1, early onset | 0.952 | ||
| RFC1 | replication factor C (activator 1) 1, 145kDa | 0.951 | ||
| BLM | Bloom syndrome, RecQ helicase-like | 0.910 | Worm Fly | |
| APITD1 | apoptosis-inducing, TAF9-like domain 1 | 0.908 | ||
| PDS5B | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.854 | ||
| BRCA2 | breast cancer 2, early onset | 0.850 | ||
| MCM6 | minichromosome maintenance complex component 6 | 0.804 | ||
| MSH5 | mutS homolog 5 (E. coli) | 0.737 | Yeast Worm | |
| RPA2 | replication protein A2, 32kDa | 0.728 | Yeast | |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.719 | ||
| RFC4 | replication factor C (activator 1) 4, 37kDa | 0.678 | ||
| MSH4 | mutS homolog 4 (E. coli) | 0.633 | Yeast | |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.623 | ||
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.608 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.565 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.542 | ||
| PCNA | proliferating cell nuclear antigen | 0.510 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.510 | ||
| MCMBP | minichromosome maintenance complex binding protein | 0.501 | ||
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.443 | ||
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.373 | ||
| FANCB | Fanconi anemia, complementation group B | 0.301 | ||
| MCM4 | minichromosome maintenance complex component 4 | 0.295 | ||
| RAD21 | RAD21 homolog (S. pombe) | 0.256 | ||
| MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 0.236 | ||
| ORC3 | origin recognition complex, subunit 3 | 0.224 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.207 | ||
| MCM3 | minichromosome maintenance complex component 3 | 0.201 | ||
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.193 | ||
| MCM2 | minichromosome maintenance complex component 2 | 0.169 | ||
| NBN | nibrin | 0.163 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.154 | ||
| STRA13 | stimulated by retinoic acid 13 homolog (mouse) | 0.144 | ||
| FANCM | Fanconi anemia, complementation group M | 0.136 | ||
| RAD51L3 | RAD51-like 3 (S. cerevisiae) | 0.120 | ||
| RAD51AP1 | RAD51 associated protein 1 | 0.100 | ||
| MSH6 | mutS homolog 6 (E. coli) | 0.097 | ||
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.094 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.090 | ||
| DSCC1 | defective in sister chromatid cohesion 1 homolog (S. cerevisiae) | 0.087 | ||
| HLTF | helicase-like transcription factor | 0.084 | ||
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 0.081 | ||
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.076 | ||
| NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.075 | ||
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.070 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.066 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.066 | ||
| RAD9A | RAD9 homolog A (S. pombe) | 0.066 | ||
| ORC1 | origin recognition complex, subunit 1 | 0.062 | ||
| RMI1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) | 0.061 | ||
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.061 | ||
| MCM7 | minichromosome maintenance complex component 7 | 0.061 | ||
| ORC6 | origin recognition complex, subunit 6 | 0.061 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.060 | Yeast | |
| PALB2 | partner and localizer of BRCA2 | 0.060 | ||
| SYCP3 | synaptonemal complex protein 3 | 0.056 | ||
| PRNP | prion protein | 0.053 | ||
| FANCG | Fanconi anemia, complementation group G | 0.049 | ||
| ATM | ataxia telangiectasia mutated | 0.048 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.048 | ||
| DMC1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | 0.048 | Yeast | |
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 0.047 | ||
| TERF2 | telomeric repeat binding factor 2 | 0.046 | ||
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.044 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.043 | ||
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 0.042 | ||
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.042 | Yeast | |
| CENPE | centromere protein E, 312kDa | 0.039 | ||
| H2AFX | H2A histone family, member X | 0.036 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.036 | ||
| FANCA | Fanconi anemia, complementation group A | 0.036 | ||
| KNTC1 | kinetochore associated 1 | 0.032 | ||
| RIF1 | RAP1 interacting factor homolog (yeast) | 0.031 | ||
| CENPM | centromere protein M | 0.031 | ||
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.031 | ||
| TPR | translocated promoter region (to activated MET oncogene) | 0.030 | ||
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.029 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.029 | ||
| RNF20 | ring finger protein 20 | 0.028 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.028 | ||
| ZNF337 | zinc finger protein 337 | 0.028 | Human | |
| C16orf75 | chromosome 16 open reading frame 75 | 0.027 | ||
| ZNF133 | zinc finger protein 133 | 0.027 | Human | |
| MSH3 | mutS homolog 3 (E. coli) | 0.027 | ||
| DCTPP1 | dCTP pyrophosphatase 1 | 0.026 | ||
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.025 | ||
| DTL | denticleless homolog (Drosophila) | 0.024 | ||
| KIF20B | kinesin family member 20B | 0.024 | ||
| TMEM106C | transmembrane protein 106C | 0.024 | ||
| RNASEH2A | ribonuclease H2, subunit A | 0.023 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.023 | ||
| CENPW | centromere protein W | 0.023 | ||
| TOP3A | topoisomerase (DNA) III alpha | 0.023 | ||
| RRM1 | ribonucleotide reductase M1 | 0.022 | ||
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.022 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.021 | ||
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.021 | ||
| MCM8 | minichromosome maintenance complex component 8 | 0.021 | Fly | |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.021 | ||
| COMMD4 | COMM domain containing 4 | 0.021 | ||
| EXO1 | exonuclease 1 | 0.021 | ||
| TRIM37 | tripartite motif containing 37 | 0.021 | ||
| POLH | polymerase (DNA directed), eta | 0.020 | ||
| SMC2 | structural maintenance of chromosomes 2 | 0.020 | ||
| MNS1 | meiosis-specific nuclear structural 1 | 0.020 | ||
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.020 | ||
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.019 | ||
| ERCC6L | excision repair cross-complementing rodent repair deficiency, complementation group 6-like | 0.019 | ||
| KIF11 | kinesin family member 11 | 0.018 | ||
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.018 | ||
| MCM10 | minichromosome maintenance complex component 10 | 0.018 | ||
| APC | adenomatous polyposis coli | 0.018 | ||
| NUP155 | nucleoporin 155kDa | 0.017 | ||
| POLE2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.017 | ||
| AKTIP | AKT interacting protein | 0.017 | ||
| CKAP5 | cytoskeleton associated protein 5 | 0.017 | ||
| MED31 | mediator complex subunit 31 | 0.017 | ||
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.016 | ||
| STIL | SCL/TAL1 interrupting locus | 0.016 | ||
| GPSM2 | G-protein signaling modulator 2 | 0.016 | ||
| FAM190B | family with sequence similarity 190, member B | 0.016 | ||
| RAD1 | RAD1 homolog (S. pombe) | 0.016 | ||
| LOC81691 | exonuclease NEF-sp | 0.015 | ||
| WASF1 | WAS protein family, member 1 | 0.015 | ||
| FANCI | Fanconi anemia, complementation group I | 0.015 | ||
| SEPT7 | septin 7 | 0.015 | ||
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 0.015 | ||
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.015 | ||
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.015 | ||
| XPA | xeroderma pigmentosum, complementation group A | 0.015 | ||
| ZNF187 | zinc finger protein 187 | 0.015 | ||
| STMN1 | stathmin 1 | 0.015 | ||
| MLH3 | mutL homolog 3 (E. coli) | 0.015 | ||
| GPS2 | G protein pathway suppressor 2 | 0.014 | ||
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.014 | ||
| BRCC3 | BRCA1/BRCA2-containing complex, subunit 3 | 0.014 | ||
| TRIM23 | tripartite motif containing 23 | 0.014 | ||
| DCLRE1A | DNA cross-link repair 1A | 0.014 | ||
| DZIP3 | DAZ interacting protein 3, zinc finger | 0.014 | ||
| EME1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.014 | ||
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.014 | ||
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.013 | ||
| SPRR2A | small proline-rich protein 2A | 0.013 | ||
| ARL11 | ADP-ribosylation factor-like 11 | 0.013 | ||
| KIF23 | kinesin family member 23 | 0.013 | ||
| UNG | uracil-DNA glycosylase | 0.013 | ||
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.013 | ||
| ERCC4 | excision repair cross-complementing rodent repair deficiency, complementation group 4 | 0.013 | ||
| MIS18BP1 | MIS18 binding protein 1 | 0.013 | ||
| TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.013 | ||
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.013 | ||
| ESCO2 | establishment of cohesion 1 homolog 2 (S. cerevisiae) | 0.013 | ||
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 0.013 | ||
| ZNF862 | zinc finger protein 862 | 0.013 | ||
| MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 0.013 | Yeast Zebrafish Mouse | |
| HDAC8 | histone deacetylase 8 | 0.013 | ||
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.012 | ||
| TUBA4A | tubulin, alpha 4a | 0.012 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.012 | ||
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | 0.012 | ||
| PFN1 | profilin 1 | 0.012 | ||
| TMSB4X | thymosin beta 4, X-linked | 0.012 | ||
| FANCL | Fanconi anemia, complementation group L | 0.012 | ||
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 0.012 | ||
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.012 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.012 | ||
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.012 | ||
| LOXL4 | lysyl oxidase-like 4 | 0.011 | ||
| CENPJ | centromere protein J | 0.011 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.011 | ||
| FKBP5 | FK506 binding protein 5 | 0.011 | ||
| STAG1 | stromal antigen 1 | 0.011 | ||
| ORC2 | origin recognition complex, subunit 2 | 0.011 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.011 | ||
| FN3KRP | fructosamine 3 kinase related protein | 0.011 | ||
| CLASP2 | cytoplasmic linker associated protein 2 | 0.011 | ||
| POLA2 | polymerase (DNA directed), alpha 2 (70kD subunit) | 0.011 | ||
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.011 | ||
| TOP1 | topoisomerase (DNA) I | 0.011 | ||
| SPC25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.011 | ||
| RECQL5 | RecQ protein-like 5 | 0.011 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.010 | ||
| CCDC77 | coiled-coil domain containing 77 | 0.010 | ||
| PLK4 | polo-like kinase 4 | 0.010 | ||
| FANCE | Fanconi anemia, complementation group E | 0.010 | ||
| GPSM1 | G-protein signaling modulator 1 | 0.010 | ||
| ALS2CR4 | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4 | 0.010 | ||
| MLF1IP | MLF1 interacting protein | 0.010 | ||
| TMEM194A | transmembrane protein 194A | 0.010 | ||
| NEK1 | NIMA (never in mitosis gene a)-related kinase 1 | 0.010 | ||
| CENPI | centromere protein I | 0.010 | ||
| ZNF16 | zinc finger protein 16 | 0.010 | ||
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | 0.010 | ||
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.010 | ||
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.010 | ||
| KIF15 | kinesin family member 15 | 0.010 | ||
| DSN1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.010 | ||
| POC5 | POC5 centriolar protein homolog (Chlamydomonas) | 0.010 |