IMP: Integrative Multi-species Prediction

Homo sapiens

25 genes annotated in human

dna templated transcription elongation

The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna templated transcription elongation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "dna templated transcription elongation" (in gray)

Name	Description	Probability	Func Analog Organism
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.989
THOC4	THO complex 4	0.913
AFF4	AF4/FMR2 family, member 4	0.878
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.878
EP300	E1A binding protein p300	0.819
DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.804
COBRA1	cofactor of BRCA1	0.777
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.773
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.696
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.601
CNOT2	CCR4-NOT transcription complex, subunit 2	0.600
SUPT5H	suppressor of Ty 5 homolog (S. cerevisiae)	0.589
HDGF	hepatoma-derived growth factor	0.485
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.455
SMAD2	SMAD family member 2	0.368
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.342
EIF4A3	eukaryotic translation initiation factor 4A3	0.342
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.314
HDAC4	histone deacetylase 4	0.286
MRFAP1	Morf4 family associated protein 1	0.275
TH1L	TH1-like (Drosophila)	0.264
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.258
TRRAP	transformation/transcription domain-associated protein	0.248
RNF11	ring finger protein 11	0.246
CNOT1	CCR4-NOT transcription complex, subunit 1	0.220	Yeast
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.202
SIRT1	sirtuin 1	0.164
CNOT3	CCR4-NOT transcription complex, subunit 3	0.132	Yeast
THOC2	THO complex 2	0.131
ARID1A	AT rich interactive domain 1A (SWI-like)	0.129
SRSF2	serine/arginine-rich splicing factor 2	0.128
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.122	Fly
THOC5	THO complex 5	0.121
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.117
CREBBP	CREB binding protein	0.111
CNOT8	CCR4-NOT transcription complex, subunit 8	0.109
XAB2	XPA binding protein 2	0.101
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.097
LMO4	LIM domain only 4	0.095
THOC1	THO complex 1	0.091
CCNT1	cyclin T1	0.090
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.089
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.082
TLK1	tousled-like kinase 1	0.082
CHTOP	chromatin target of PRMT1	0.081
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.080
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.075
CHD8	chromodomain helicase DNA binding protein 8	0.074
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.074
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.071
RSF1	remodeling and spacing factor 1	0.069
PRRC2C	proline-rich coiled-coil 2C	0.068
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.066
CDAN1	congenital dyserythropoietic anemia, type I	0.064
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.064
CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	0.062
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.062
NCOR1	nuclear receptor corepressor 1	0.061
TCF12	transcription factor 12	0.061
SSRP1	structure specific recognition protein 1	0.061
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.059
STRN4	striatin, calmodulin binding protein 4	0.058
KAT5	K(lysine) acetyltransferase 5	0.056	Yeast
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.056	Yeast
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.056
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.055
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.055
TRIM33	tripartite motif containing 33	0.054	Zebrafish
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.052
RBM42	RNA binding motif protein 42	0.051
CHD4	chromodomain helicase DNA binding protein 4	0.051
NCOA6	nuclear receptor coactivator 6	0.050
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.050
MTA1	metastasis associated 1	0.049
KDM2A	lysine (K)-specific demethylase 2A	0.045
TCEA1	transcription elongation factor A (SII), 1	0.045	Yeast
EAF1	ELL associated factor 1	0.044
CNOT6	CCR4-NOT transcription complex, subunit 6	0.044	Yeast
HDAC1	histone deacetylase 1	0.044
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.044
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.043
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.042
UBE3A	ubiquitin protein ligase E3A	0.042
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.041
CREB1	cAMP responsive element binding protein 1	0.040
PRRC2A	proline-rich coiled-coil 2A	0.038
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.038
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.038
NXF1	nuclear RNA export factor 1	0.038
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.038
ACIN1	apoptotic chromatin condensation inducer 1	0.037
TRIM28	tripartite motif containing 28	0.036
MED26	mediator complex subunit 26	0.035
IK	IK cytokine, down-regulator of HLA II	0.035
MEF2A	myocyte enhancer factor 2A	0.034	Fly
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.034
JMJD6	jumonji domain containing 6	0.033
YY1	YY1 transcription factor	0.033
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.032	Rat
HABP4	hyaluronan binding protein 4	0.032
EWSR1	Ewing sarcoma breakpoint region 1	0.032
CUX1	cut-like homeobox 1	0.031
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.031
DBC1	deleted in bladder cancer 1	0.031
GTF2B	general transcription factor IIB	0.030
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.029
RAD23B	RAD23 homolog B (S. cerevisiae)	0.029
ATXN3	ataxin 3	0.029
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.029
C20orf20	chromosome 20 open reading frame 20	0.027
WDR61	WD repeat domain 61	0.027
CNOT10	CCR4-NOT transcription complex, subunit 10	0.027
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.027
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.027
HDAC9	histone deacetylase 9	0.027
TADA2A	transcriptional adaptor 2A	0.027
CABIN1	calcineurin binding protein 1	0.026
TCF4	transcription factor 4	0.026
ATXN7	ataxin 7	0.026
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.026
CDR2	cerebellar degeneration-related protein 2, 62kDa	0.026
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.025
ERH	enhancer of rudimentary homolog (Drosophila)	0.025
MMS22L	MMS22-like, DNA repair protein	0.025
TP53BP1	tumor protein p53 binding protein 1	0.025
DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	0.025	Human Yeast
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.025
BRD4	bromodomain containing 4	0.024
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.024
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.023
UVRAG	UV radiation resistance associated gene	0.023
TRAF5	TNF receptor-associated factor 5	0.022
MYO6	myosin VI	0.021
SRSF3	serine/arginine-rich splicing factor 3	0.020
H3F3A	H3 histone, family 3A	0.020
MED15	mediator complex subunit 15	0.019
CNOT7	CCR4-NOT transcription complex, subunit 7	0.019
MARK3	MAP/microtubule affinity-regulating kinase 3	0.018
HEXIM1	hexamethylene bis-acetamide inducible 1	0.018
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.018
SMAD3	SMAD family member 3	0.018
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.017
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.017
CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	0.017
WHSC2	Wolf-Hirschhorn syndrome candidate 2	0.017	Fly
NCOA1	nuclear receptor coactivator 1	0.017
BECN1	beclin 1, autophagy related	0.017
UBE2S	ubiquitin-conjugating enzyme E2S	0.017
UBN1	ubinuclein 1	0.016
MED12	mediator complex subunit 12	0.016
SNW1	SNW domain containing 1	0.015
EED	embryonic ectoderm development	0.015
MEF2C	myocyte enhancer factor 2C	0.015	Fly
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.015
FAM190B	family with sequence similarity 190, member B	0.015
KDM3B	lysine (K)-specific demethylase 3B	0.015
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.015	Yeast
ANKRD13A	ankyrin repeat domain 13A	0.015
RSRC2	arginine/serine-rich coiled-coil 2	0.015
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.015
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.014
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.014
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.014
NCOA3	nuclear receptor coactivator 3	0.014
MSH6	mutS homolog 6 (E. coli)	0.014
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.014
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.014
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.014
CDT1	chromatin licensing and DNA replication factor 1	0.014
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.013
NUP153	nucleoporin 153kDa	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
LARP7	La ribonucleoprotein domain family, member 7	0.013
C19orf53	chromosome 19 open reading frame 53	0.013
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.013	Yeast
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.013
PEBP4	phosphatidylethanolamine-binding protein 4	0.013
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.013
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.013
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.013
PAXIP1	PAX interacting (with transcription-activation domain) protein 1	0.013
MAGED2	melanoma antigen family D, 2	0.013
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.013
SSBP2	single-stranded DNA binding protein 2	0.012
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.012
MUDENG	MU-2/AP1M2 domain containing, death-inducing	0.012
RAD23A	RAD23 homolog A (S. cerevisiae)	0.012
TOP1	topoisomerase (DNA) I	0.012	Yeast
CIC	capicua homolog (Drosophila)	0.012
ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	0.012
SMAD7	SMAD family member 7	0.012
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.012
ZNRF1	zinc and ring finger 1	0.011
RUNX1	runt-related transcription factor 1	0.011
THOC6	THO complex 6 homolog (Drosophila)	0.011
EPS15	epidermal growth factor receptor pathway substrate 15	0.011
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.011
PCNA	proliferating cell nuclear antigen	0.011
PIK3C3	phosphoinositide-3-kinase, class 3	0.011	Yeast
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.011
NBN	nibrin	0.011
ZMAT2	zinc finger, matrin-type 2	0.011
SRSF10	serine/arginine-rich splicing factor 10	0.011
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.011
TRAF3	TNF receptor-associated factor 3	0.011
RLIM	ring finger protein, LIM domain interacting	0.010
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.010
BTG2	BTG family, member 2	0.010
ZBTB17	zinc finger and BTB domain containing 17	0.010
RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.010
TRIP12	thyroid hormone receptor interactor 12	0.010
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.010
SON	SON DNA binding protein	0.010
FCHO2	FCH domain only 2	0.010
DUSP3	dual specificity phosphatase 3	0.010