IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

dna templated transcription termination

The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna templated transcription termination"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "dna templated transcription termination" (in gray)

Name	Description	Probability	Func Analog Organism
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.582
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.146
TOP1	topoisomerase (DNA) I	0.117
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.115
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.087
CAV2	caveolin 2	0.082
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.081
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.079	Yeast
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.077
RBMX	RNA binding motif protein, X-linked	0.067
ASNS	asparagine synthetase (glutamine-hydrolyzing)	0.067
CAV1	caveolin 1, caveolae protein, 22kDa	0.058
AARS	alanyl-tRNA synthetase	0.058
YARS	tyrosyl-tRNA synthetase	0.054
MARS	methionyl-tRNA synthetase	0.047
CARS	cysteinyl-tRNA synthetase	0.047
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.046
YBX1	Y box binding protein 1	0.046
HAX1	HCLS1 associated protein X-1	0.046
RBM8A	RNA binding motif protein 8A	0.045
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.038
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.038
IARS	isoleucyl-tRNA synthetase	0.034
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	0.033
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.032
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.032
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.032
YTHDC1	YTH domain containing 1	0.031
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.030
RAD18	RAD18 homolog (S. cerevisiae)	0.029
AATF	apoptosis antagonizing transcription factor	0.028
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.028
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.028
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.028
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.027
SARS	seryl-tRNA synthetase	0.027
AEBP2	AE binding protein 2	0.026
SRSF2	serine/arginine-rich splicing factor 2	0.026
SRPK2	SRSF protein kinase 2	0.026
MED13	mediator complex subunit 13	0.025
RNF20	ring finger protein 20	0.023
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.023
SRSF3	serine/arginine-rich splicing factor 3	0.022	Worm
HABP4	hyaluronan binding protein 4	0.022
PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.022
NUP153	nucleoporin 153kDa	0.021
EHD2	EH-domain containing 2	0.020
NONO	non-POU domain containing, octamer-binding	0.020
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.020
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.020
RAD21	RAD21 homolog (S. pombe)	0.019
CELF1	CUGBP, Elav-like family member 1	0.019
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.019
TARS	threonyl-tRNA synthetase	0.018
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.018
EWSR1	Ewing sarcoma breakpoint region 1	0.018
RYBP	RING1 and YY1 binding protein	0.018
SFPQ	splicing factor proline/glutamine-rich	0.018
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.018
LMTK2	lemur tyrosine kinase 2	0.017
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.017
BANF1	barrier to autointegration factor 1	0.017
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.016
ERH	enhancer of rudimentary homolog (Drosophila)	0.016
FAM190B	family with sequence similarity 190, member B	0.016
SP3	Sp3 transcription factor	0.016
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.016
SRSF8	serine/arginine-rich splicing factor 8	0.016
RBM39	RNA binding motif protein 39	0.015
H3F3B	H3 histone, family 3B (H3.3B)	0.015
MAGED2	melanoma antigen family D, 2	0.015
YTHDF2	YTH domain family, member 2	0.015
WDR61	WD repeat domain 61	0.015
CHTOP	chromatin target of PRMT1	0.015
ZNF830	zinc finger protein 830	0.014
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.014
POLR2J2	polymerase (RNA) II (DNA directed) polypeptide J2	0.014
POLR2J	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	0.013	Yeast
CNBP	CCHC-type zinc finger, nucleic acid binding protein	0.013
DCC	deleted in colorectal carcinoma	0.013
SON	SON DNA binding protein	0.013
DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	0.013
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.012
FMR1	fragile X mental retardation 1	0.012
ARL15	ADP-ribosylation factor-like 15	0.012
DLC1	deleted in liver cancer 1	0.012
MAGEA11	melanoma antigen family A, 11	0.012
MED29	mediator complex subunit 29	0.012
ILF2	interleukin enhancer binding factor 2, 45kDa	0.012
PCBP2	poly(rC) binding protein 2	0.012
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.011
OSGEP	O-sialoglycoprotein endopeptidase	0.011
UBQLN2	ubiquilin 2	0.011
SCAF8	SR-related CTD-associated factor 8	0.011
FBXO11	F-box protein 11	0.011
MYL9	myosin, light chain 9, regulatory	0.011
SMNDC1	survival motor neuron domain containing 1	0.011
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.011
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.011
BCLAF1	BCL2-associated transcription factor 1	0.011
PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	0.011
RBM23	RNA binding motif protein 23	0.011
BTBD2	BTB (POZ) domain containing 2	0.011
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.011
SLC2A4RG	SLC2A4 regulator	0.011
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.011
TOP2B	topoisomerase (DNA) II beta 180kDa	0.011
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.010
H1FX	H1 histone family, member X	0.010
WDR82	WD repeat domain 82	0.010	Yeast
RDBP	RD RNA binding protein	0.010
LUC7L	LUC7-like (S. cerevisiae)	0.010
PUM1	pumilio homolog 1 (Drosophila)	0.010
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.010
CNN3	calponin 3, acidic	0.010
DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1	0.010
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.010
RBM22	RNA binding motif protein 22	0.010
F2R	coagulation factor II (thrombin) receptor	0.010
SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)	0.010