IMP: Integrative Multi-species Prediction

Homo sapiens

50 genes annotated in human

cellular response to reactive oxygen species

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to reactive oxygen species"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular response to reactive oxygen species" (in gray)

Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000
JUN	jun proto-oncogene	0.996
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.992	Human
DUSP1	dual specificity phosphatase 1	0.949
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.924
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.904	Human
MAPK14	mitogen-activated protein kinase 14	0.886	Fly
CRYBB2	crystallin, beta B2	0.829
ATF2	activating transcription factor 2	0.812
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.781	Rat
CRYAB	crystallin, alpha B	0.759
PRDX1	peroxiredoxin 1	0.708
KLF6	Kruppel-like factor 6	0.690	Rat
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.671	Human
CAV1	caveolin 1, caveolae protein, 22kDa	0.621
TTR	transthyretin	0.619
HBB	hemoglobin, beta	0.615
CRYAA	crystallin, alpha A	0.580
CREBBP	CREB binding protein	0.570
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.569	Human
HBA2	hemoglobin, alpha 2	0.547
ATF3	activating transcription factor 3	0.540	Human
BCL3	B-cell CLL/lymphoma 3	0.506
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.499
GAS6	growth arrest-specific 6	0.498
MPDZ	multiple PDZ domain protein	0.468
ARHGAP1	Rho GTPase activating protein 1	0.452
DAXX	death-domain associated protein	0.445
AR	androgen receptor	0.433
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.428
KEAP1	kelch-like ECH-associated protein 1	0.379
SOD1	superoxide dismutase 1, soluble	0.375
FHL2	four and a half LIM domains 2	0.333
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.314
ARRB1	arrestin, beta 1	0.314
MAPK1	mitogen-activated protein kinase 1	0.311	Fly
HBG2	hemoglobin, gamma G	0.296
JUNB	jun B proto-oncogene	0.288
PRDX4	peroxiredoxin 4	0.271	Human Worm
CRYBA2	crystallin, beta A2	0.252	Human
RUNX1	runt-related transcription factor 1	0.249
TXN	thioredoxin	0.244
PARK7	Parkinson disease (autosomal recessive, early onset) 7	0.239
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.237	Human
CRYBB1	crystallin, beta B1	0.228	Human
PLAU	plasminogen activator, urokinase	0.226	Human
ACACA	acetyl-CoA carboxylase alpha	0.224
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.217
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.203
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.189
EGFR	epidermal growth factor receptor	0.187
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.185
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.177
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.176
SOCS3	suppressor of cytokine signaling 3	0.175
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.171
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.167
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.163
GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)	0.158
PTK2	PTK2 protein tyrosine kinase 2	0.144
LZTS2	leucine zipper, putative tumor suppressor 2	0.136
MAPK8	mitogen-activated protein kinase 8	0.133	Mouse Fly
PLAUR	plasminogen activator, urokinase receptor	0.131
FTL	ferritin, light polypeptide	0.129
JUND	jun D proto-oncogene	0.126
MAP2K4	mitogen-activated protein kinase kinase 4	0.125
APLP2	amyloid beta (A4) precursor-like protein 2	0.123
PTN	pleiotrophin	0.122
PML	promyelocytic leukemia	0.117
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.115
MAPK3	mitogen-activated protein kinase 3	0.111	Fly
PGR	progesterone receptor	0.104
PDZD11	PDZ domain containing 11	0.103
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.103
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.096
C3	complement component 3	0.092
SQSTM1	sequestosome 1	0.092
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.088
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.088
LTBP2	latent transforming growth factor beta binding protein 2	0.087
MAP2K5	mitogen-activated protein kinase kinase 5	0.087
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.086
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.086
IL6R	interleukin 6 receptor	0.085
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.083
IL4R	interleukin 4 receptor	0.081
CRYGC	crystallin, gamma C	0.080	Human
PLAT	plasminogen activator, tissue	0.078	Human
CTSD	cathepsin D	0.078
TSC22D4	TSC22 domain family, member 4	0.076
SMAD3	SMAD family member 3	0.075
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.075
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.074
CRYBB3	crystallin, beta B3	0.074	Human
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.073
MAPK10	mitogen-activated protein kinase 10	0.069	Fly
MAPT	microtubule-associated protein tau	0.068
NCOA6	nuclear receptor coactivator 6	0.066
NCOR2	nuclear receptor corepressor 2	0.065
LOXL1	lysyl oxidase-like 1	0.065
APOE	apolipoprotein E	0.065
LPXN	leupaxin	0.063	Human
HSPB1	heat shock 27kDa protein 1	0.063
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.063	Human
SMAD2	SMAD family member 2	0.063
ILK	integrin-linked kinase	0.060
MAP2K3	mitogen-activated protein kinase kinase 3	0.058
LIMS1	LIM and senescent cell antigen-like domains 1	0.058	Human
KLF4	Kruppel-like factor 4 (gut)	0.058	Rat
KAT2B	K(lysine) acetyltransferase 2B	0.057
ESR1	estrogen receptor 1	0.055
FOSL2	FOS-like antigen 2	0.054	Human
ITGA7	integrin, alpha 7	0.054
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.054
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.052
HDAC2	histone deacetylase 2	0.051
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.050
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.049
PTRF	polymerase I and transcript release factor	0.049
LOX	lysyl oxidase	0.049
PRDX2	peroxiredoxin 2	0.049
PHC2	polyhomeotic homolog 2 (Drosophila)	0.048
TP53	tumor protein p53	0.048
HP	haptoglobin	0.048
THBS1	thrombospondin 1	0.048	Mouse
CRYBA4	crystallin, beta A4	0.047	Human
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.047
IL1R1	interleukin 1 receptor, type I	0.047
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.047
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.047
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.046
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.045
EP300	E1A binding protein p300	0.044
ICAM1	intercellular adhesion molecule 1	0.044
BID	BH3 interacting domain death agonist	0.044
BIRC3	baculoviral IAP repeat containing 3	0.044
HOXA1	homeobox A1	0.044
ING2	inhibitor of growth family, member 2	0.043
NCK2	NCK adaptor protein 2	0.042
SPTBN1	spectrin, beta, non-erythrocytic 1	0.042
RHOB	ras homolog gene family, member B	0.041
VDAC1	voltage-dependent anion channel 1	0.041
PRDX6	peroxiredoxin 6	0.041	Rat
USP11	ubiquitin specific peptidase 11	0.040
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.040
GAB1	GRB2-associated binding protein 1	0.040
PARVA	parvin, alpha	0.040
HBE1	hemoglobin, epsilon 1	0.040
GSN	gelsolin	0.040
HBD	hemoglobin, delta	0.040
VCL	vinculin	0.039
HADH	hydroxyacyl-CoA dehydrogenase	0.039
IL8	interleukin 8	0.039
WRN	Werner syndrome, RecQ helicase-like	0.039
CRYBA1	crystallin, beta A1	0.038	Human
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.038
LCAT	lecithin-cholesterol acyltransferase	0.038
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.038	Rat
HSPB2	heat shock 27kDa protein 2	0.038
MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	0.037
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.037
PLXNB1	plexin B1	0.037
NCOA3	nuclear receptor coactivator 3	0.037
PRDX3	peroxiredoxin 3	0.036
PGK1	phosphoglycerate kinase 1	0.036
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.036
FBXO7	F-box protein 7	0.036
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.036
PRMT2	protein arginine methyltransferase 2	0.036
HNF4A	hepatocyte nuclear factor 4, alpha	0.036
NCOA2	nuclear receptor coactivator 2	0.036
TIMP3	TIMP metallopeptidase inhibitor 3	0.035
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.035
CXCL3	chemokine (C-X-C motif) ligand 3	0.034
APOC3	apolipoprotein C-III	0.034
MAP2K6	mitogen-activated protein kinase kinase 6	0.034
FCGRT	Fc fragment of IgG, receptor, transporter, alpha	0.033
FOXO3	forkhead box O3	0.033
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.032
S100B	S100 calcium binding protein B	0.032
APP	amyloid beta (A4) precursor protein	0.032
FOSL1	FOS-like antigen 1	0.031	Human
APOA1	apolipoprotein A-I	0.031	Human
RAB5B	RAB5B, member RAS oncogene family	0.031
TNIP2	TNFAIP3 interacting protein 2	0.031
RBPMS	RNA binding protein with multiple splicing	0.030
TIMP1	TIMP metallopeptidase inhibitor 1	0.030
CFHR1	complement factor H-related 1	0.030
CTSA	cathepsin A	0.030
FAS	Fas (TNF receptor superfamily, member 6)	0.030	Rat
CYR61	cysteine-rich, angiogenic inducer, 61	0.030
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.030
FOXO1	forkhead box O1	0.029	Mouse
ACTN1	actinin, alpha 1	0.029
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.029
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.029
FBN1	fibrillin 1	0.029
SMAD1	SMAD family member 1	0.028
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.028
BLNK	B-cell linker	0.028
TMEM173	transmembrane protein 173	0.028
GRPEL1	GrpE-like 1, mitochondrial (E. coli)	0.028
GAA	glucosidase, alpha; acid	0.027
RING1	ring finger protein 1	0.027
CNN1	calponin 1, basic, smooth muscle	0.027
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.027
IL4	interleukin 4	0.027
NOG	noggin	0.027
ZNF512B	zinc finger protein 512B	0.027
TPP1	tripeptidyl peptidase I	0.026
NCOA1	nuclear receptor coactivator 1	0.026
BCL6	B-cell CLL/lymphoma 6	0.026
DUSP3	dual specificity phosphatase 3	0.026
CTBP1	C-terminal binding protein 1	0.026
HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	0.025
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.025
HSPB8	heat shock 22kDa protein 8	0.025
DAD1	defender against cell death 1	0.025
ALAS2	aminolevulinate, delta-, synthase 2	0.025
TRAF1	TNF receptor-associated factor 1	0.025
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.025
TGIF1	TGFB-induced factor homeobox 1	0.025
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.025
CXCL2	chemokine (C-X-C motif) ligand 2	0.025
ADRBK1	adrenergic, beta, receptor kinase 1	0.025
SP100	SP100 nuclear antigen	0.025
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.024
TIMP2	TIMP metallopeptidase inhibitor 2	0.024
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.024
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.024
PDLIM7	PDZ and LIM domain 7 (enigma)	0.024
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.024	Rat
HBZ	hemoglobin, zeta	0.024	Human
HGFAC	HGF activator	0.024	Human
HSPA1B	heat shock 70kDa protein 1B	0.024
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.024
FTH1	ferritin, heavy polypeptide 1	0.024
PHF21A	PHD finger protein 21A	0.024
RNF19B	ring finger protein 19B	0.024
EPAS1	endothelial PAS domain protein 1	0.023
TPM4	tropomyosin 4	0.023	Human
SSTR3	somatostatin receptor 3	0.023
ORM1	orosomucoid 1	0.023
DAB2IP	DAB2 interacting protein	0.023
GADD45B	growth arrest and DNA-damage-inducible, beta	0.023
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.023
CPNE6	copine VI (neuronal)	0.023
CALCOCO1	calcium binding and coiled-coil domain 1	0.023
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.023
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.023
KLF2	Kruppel-like factor 2 (lung)	0.023	Rat
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.022
EMP1	epithelial membrane protein 1	0.022
EHHADH	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	0.022
KCTD17	potassium channel tetramerisation domain containing 17	0.022
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.022
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.022
CKS2	CDC28 protein kinase regulatory subunit 2	0.022
SP1	Sp1 transcription factor	0.022
ANXA1	annexin A1	0.022
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.022
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	0.022
PBK	PDZ binding kinase	0.022
TSC22D3	TSC22 domain family, member 3	0.022
CTSB	cathepsin B	0.021
KNG1	kininogen 1	0.021
DDIT3	DNA-damage-inducible transcript 3	0.021
GEM	GTP binding protein overexpressed in skeletal muscle	0.021
TPM1	tropomyosin 1 (alpha)	0.021
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.021
CTGF	connective tissue growth factor	0.021
PGLYRP1	peptidoglycan recognition protein 1	0.021
CFD	complement factor D (adipsin)	0.020
VHL	von Hippel-Lindau tumor suppressor	0.020
EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	0.020
RGS2	regulator of G-protein signaling 2, 24kDa	0.020
FGFR1	fibroblast growth factor receptor 1	0.020
CAV2	caveolin 2	0.020
FGB	fibrinogen beta chain	0.020
PRKCA	protein kinase C, alpha	0.020
PDE4DIP	phosphodiesterase 4D interacting protein	0.020
PPARA	peroxisome proliferator-activated receptor alpha	0.020
CCND2	cyclin D2	0.020
ZNF426	zinc finger protein 426	0.020
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.020	Human
PRTN3	proteinase 3	0.020
LRDD	leucine-rich repeats and death domain containing	0.020
YY1	YY1 transcription factor	0.019
MYL9	myosin, light chain 9, regulatory	0.019
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.019
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.019
EED	embryonic ectoderm development	0.019
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.019
PRKCZ	protein kinase C, zeta	0.019
ADAMTSL4	ADAMTS-like 4	0.019
PLD3	phospholipase D family, member 3	0.019
F2	coagulation factor II (thrombin)	0.019
CTTN	cortactin	0.019
SS18	synovial sarcoma translocation, chromosome 18	0.019
ARID3A	AT rich interactive domain 3A (BRIGHT-like)	0.019
FASN	fatty acid synthase	0.019
FGA	fibrinogen alpha chain	0.019
GCGR	glucagon receptor	0.019
SNCAIP	synuclein, alpha interacting protein	0.019
BRCA1	breast cancer 1, early onset	0.018
PRDX5	peroxiredoxin 5	0.018
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.018
PHF1	PHD finger protein 1	0.018
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.018
LRP1	low density lipoprotein receptor-related protein 1	0.018
GYPB	glycophorin B (MNS blood group)	0.018
DDR1	discoidin domain receptor tyrosine kinase 1	0.018
GTF2I	general transcription factor IIi	0.018
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.018
KLF1	Kruppel-like factor 1 (erythroid)	0.018
NPC2	Niemann-Pick disease, type C2	0.018
BTG2	BTG family, member 2	0.018
VEGFC	vascular endothelial growth factor C	0.018
ELANE	elastase, neutrophil expressed	0.018
HMOX1	heme oxygenase (decycling) 1	0.018
GNS	glucosamine (N-acetyl)-6-sulfatase	0.018
SPHK1	sphingosine kinase 1	0.018	Rat
SYN1	synapsin I	0.017
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.017
AMBP	alpha-1-microglobulin/bikunin precursor	0.017
SOCS1	suppressor of cytokine signaling 1	0.017
CBX7	chromobox homolog 7	0.017
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.017
DUSP9	dual specificity phosphatase 9	0.017
FN1	fibronectin 1	0.017
CLU	clusterin	0.017
TNIP1	TNFAIP3 interacting protein 1	0.017
TALDO1	transaldolase 1	0.017
LAMB2	laminin, beta 2 (laminin S)	0.017
CUL7	cullin 7	0.017
COL5A1	collagen, type V, alpha 1	0.017
HDAC8	histone deacetylase 8	0.017
RB1	retinoblastoma 1	0.017
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.017
SYK	spleen tyrosine kinase	0.017
PEA15	phosphoprotein enriched in astrocytes 15	0.017
DUSP23	dual specificity phosphatase 23	0.017
GJC2	gap junction protein, gamma 2, 47kDa	0.017
LTF	lactotransferrin	0.017
TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	0.016
HDAC1	histone deacetylase 1	0.016
TXNIP	thioredoxin interacting protein	0.016
NQO1	NAD(P)H dehydrogenase, quinone 1	0.016	Rat
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.016
CD44	CD44 molecule (Indian blood group)	0.016
TCN2	transcobalamin II	0.016
ALDOB	aldolase B, fructose-bisphosphate	0.016
TRIO	triple functional domain (PTPRF interacting)	0.016
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.016
TBXA2R	thromboxane A2 receptor	0.016
MARCH2	membrane-associated ring finger (C3HC4) 2	0.016
DEFA4	defensin, alpha 4, corticostatin	0.016
THBD	thrombomodulin	0.016
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	0.016
BBS1	Bardet-Biedl syndrome 1	0.016
TRIP6	thyroid hormone receptor interactor 6	0.016
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.016
ACHE	acetylcholinesterase	0.016
OSMR	oncostatin M receptor	0.016
NNMT	nicotinamide N-methyltransferase	0.016
KLF5	Kruppel-like factor 5 (intestinal)	0.016
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.016
TRAF4	TNF receptor-associated factor 4	0.016
GAB2	GRB2-associated binding protein 2	0.016
SGK1	serum/glucocorticoid regulated kinase 1	0.016
MEX3C	mex-3 homolog C (C. elegans)	0.016
IGFALS	insulin-like growth factor binding protein, acid labile subunit	0.016
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.016
GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	0.016
LEPR	leptin receptor	0.016
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.016
PF4	platelet factor 4	0.016
SPP2	secreted phosphoprotein 2, 24kDa	0.015
CAMP	cathelicidin antimicrobial peptide	0.015
MAP1B	microtubule-associated protein 1B	0.015
MDH1	malate dehydrogenase 1, NAD (soluble)	0.015
SIRT2	sirtuin 2	0.015
ZC3H12A	zinc finger CCCH-type containing 12A	0.015
CHUK	conserved helix-loop-helix ubiquitous kinase	0.015
PCNA	proliferating cell nuclear antigen	0.015
MAPK15	mitogen-activated protein kinase 15	0.015
LRP6	low density lipoprotein receptor-related protein 6	0.015
PDIA6	protein disulfide isomerase family A, member 6	0.015
IGFBP6	insulin-like growth factor binding protein 6	0.015
SMAD7	SMAD family member 7	0.015
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.015
LMNA	lamin A/C	0.015
APOB	apolipoprotein B (including Ag(x) antigen)	0.015
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.015
C8B	complement component 8, beta polypeptide	0.015
CTSL1	cathepsin L1	0.015
APLF	aprataxin and PNKP like factor	0.015
C8A	complement component 8, alpha polypeptide	0.015
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.015
MEF2C	myocyte enhancer factor 2C	0.015
HBEGF	heparin-binding EGF-like growth factor	0.015
CNGB1	cyclic nucleotide gated channel beta 1	0.015
INHBA	inhibin, beta A	0.014
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.014
SAT1	spermidine/spermine N1-acetyltransferase 1	0.014
DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	0.014
F11	coagulation factor XI	0.014
CTSE	cathepsin E	0.014
PDK4	pyruvate dehydrogenase kinase, isozyme 4	0.014	Human
CD320	CD320 molecule	0.014
TBC1D17	TBC1 domain family, member 17	0.014
NBN	nibrin	0.014
SMTN	smoothelin	0.014
ZBTB16	zinc finger and BTB domain containing 16	0.014
HSPA1A	heat shock 70kDa protein 1A	0.014
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.014
ACSL1	acyl-CoA synthetase long-chain family member 1	0.014
SELENBP1	selenium binding protein 1	0.014
CTSF	cathepsin F	0.014
IGFBP3	insulin-like growth factor binding protein 3	0.014
CCL2	chemokine (C-C motif) ligand 2	0.014
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.014	Human
FAM107A	family with sequence similarity 107, member A	0.014
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.014
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.014
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.014
SLPI	secretory leukocyte peptidase inhibitor	0.014
ZBTB7B	zinc finger and BTB domain containing 7B	0.014
CLCF1	cardiotrophin-like cytokine factor 1	0.014
PGRMC1	progesterone receptor membrane component 1	0.014
SBNO2	strawberry notch homolog 2 (Drosophila)	0.014
LNX1	ligand of numb-protein X 1	0.014
COL4A2	collagen, type IV, alpha 2	0.014
CNN2	calponin 2	0.014
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.014
TPPP	tubulin polymerization promoting protein	0.014
GABARAP	GABA(A) receptor-associated protein	0.014
CBX8	chromobox homolog 8	0.014
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	0.014
ZYX	zyxin	0.014
COL8A1	collagen, type VIII, alpha 1	0.014
MEF2D	myocyte enhancer factor 2D	0.014
ELN	elastin	0.014
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.014
TXNRD1	thioredoxin reductase 1	0.014	Rat
DPYS	dihydropyrimidinase	0.014
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.014
AGXT	alanine-glyoxylate aminotransferase	0.013
HPR	haptoglobin-related protein	0.013
AZU1	azurocidin 1	0.013
SOS2	son of sevenless homolog 2 (Drosophila)	0.013
SFTPC	surfactant protein C	0.013
COL4A1	collagen, type IV, alpha 1	0.013
MGST1	microsomal glutathione S-transferase 1	0.013
TRAF3	TNF receptor-associated factor 3	0.013
PROCR	protein C receptor, endothelial	0.013
SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	0.013
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.013
MASP2	mannan-binding lectin serine peptidase 2	0.013
LBP	lipopolysaccharide binding protein	0.013
NEU1	sialidase 1 (lysosomal sialidase)	0.013
TFR2	transferrin receptor 2	0.013
SEPT4	septin 4	0.013
S100A1	S100 calcium binding protein A1	0.013
FABP4	fatty acid binding protein 4, adipocyte	0.013
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.013
MXD1	MAX dimerization protein 1	0.013
UTRN	utrophin	0.013
PER1	period homolog 1 (Drosophila)	0.013
HPD	4-hydroxyphenylpyruvate dioxygenase	0.013
CFI	complement factor I	0.013
RBBP8	retinoblastoma binding protein 8	0.013
PLSCR4	phospholipid scramblase 4	0.013
KCTD3	potassium channel tetramerisation domain containing 3	0.013
MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2	0.013
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.013	Human
JDP2	Jun dimerization protein 2	0.013	Human
AHR	aryl hydrocarbon receptor	0.013
DCTN1	dynactin 1	0.013
RAD51AP1	RAD51 associated protein 1	0.013
FILIP1L	filamin A interacting protein 1-like	0.013
TAGLN	transgelin	0.013
CRP	C-reactive protein, pentraxin-related	0.013
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.013
CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	0.013
UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	0.013
RETN	resistin	0.013
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.013
ADAM19	ADAM metallopeptidase domain 19	0.013
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.013
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.013
ZNF358	zinc finger protein 358	0.013
GRN	granulin	0.013
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.013
VTN	vitronectin	0.013
FAM65A	family with sequence similarity 65, member A	0.012
CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.012
ACAN	aggrecan	0.012
DAPK1	death-associated protein kinase 1	0.012
GLRX	glutaredoxin (thioltransferase)	0.012
DLG1	discs, large homolog 1 (Drosophila)	0.012
RACGAP1	Rac GTPase activating protein 1	0.012
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.012
TIFA	TRAF-interacting protein with forkhead-associated domain	0.012
S100P	S100 calcium binding protein P	0.012
GPX3	glutathione peroxidase 3 (plasma)	0.012	Rat
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.012
PDZK1IP1	PDZK1 interacting protein 1	0.012
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.012
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.012
KLF7	Kruppel-like factor 7 (ubiquitous)	0.012
DMBT1	deleted in malignant brain tumors 1	0.012
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.012
LTBP1	latent transforming growth factor beta binding protein 1	0.012
MAP2K7	mitogen-activated protein kinase kinase 7	0.012
CA4	carbonic anhydrase IV	0.012
MAPK12	mitogen-activated protein kinase 12	0.012	Fly
APOC1	apolipoprotein C-I	0.012
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.012	Human
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.012
GSTO1	glutathione S-transferase omega 1	0.012
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.012
MAVS	mitochondrial antiviral signaling protein	0.012
GRK1	G protein-coupled receptor kinase 1	0.012
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.012
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.012
NCKAP1	NCK-associated protein 1	0.012
RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	0.012
PTPRN	protein tyrosine phosphatase, receptor type, N	0.012
CREB1	cAMP responsive element binding protein 1	0.012
CYLD	cylindromatosis (turban tumor syndrome)	0.012
IRS4	insulin receptor substrate 4	0.012
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.012
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.012
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.012
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.012
PRKD1	protein kinase D1	0.012
TPSD1	tryptase delta 1	0.012
PON3	paraoxonase 3	0.012
OBSL1	obscurin-like 1	0.012
ZBTB25	zinc finger and BTB domain containing 25	0.012
PTX3	pentraxin 3, long	0.012
DYNLL1	dynein, light chain, LC8-type 1	0.012
PGCP	plasma glutamate carboxypeptidase	0.012
PDIA2	protein disulfide isomerase family A, member 2	0.012
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.012
ALPI	alkaline phosphatase, intestinal	0.012
MAGEB18	melanoma antigen family B, 18	0.012
C13orf15	chromosome 13 open reading frame 15	0.012
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.012
GUCA2B	guanylate cyclase activator 2B (uroguanylin)	0.012
TAGLN2	transgelin 2	0.012
GCLM	glutamate-cysteine ligase, modifier subunit	0.012
SMAD4	SMAD family member 4	0.012
APCS	amyloid P component, serum	0.012
TUBB2A	tubulin, beta 2A	0.012
CBX6	chromobox homolog 6	0.012
PDE2A	phosphodiesterase 2A, cGMP-stimulated	0.012
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.012
POM121	POM121 membrane glycoprotein	0.012
MYOF	myoferlin	0.011
FLNC	filamin C, gamma	0.011
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.011
AFM	afamin	0.011
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.011
BABAM1	BRISC and BRCA1 A complex member 1	0.011
LIPC	lipase, hepatic	0.011
ACTA2	actin, alpha 2, smooth muscle, aorta	0.011
GNMT	glycine N-methyltransferase	0.011
PICK1	protein interacting with PRKCA 1	0.011
ALB	albumin	0.011
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.011
HRH1	histamine receptor H1	0.011
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.011
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.011
CP	ceruloplasmin (ferroxidase)	0.011
AMT	aminomethyltransferase	0.011
ESR2	estrogen receptor 2 (ER beta)	0.011
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.011
GCKR	glucokinase (hexokinase 4) regulator	0.011
PRODH2	proline dehydrogenase (oxidase) 2	0.011
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.011	Human
TGFB2	transforming growth factor, beta 2	0.011
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.011
TSPO	translocator protein (18kDa)	0.011
DUSP16	dual specificity phosphatase 16	0.011
S1PR1	sphingosine-1-phosphate receptor 1	0.011
PKN2	protein kinase N2	0.011
ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.011
COMMD1	copper metabolism (Murr1) domain containing 1	0.011
C1S	complement component 1, s subcomponent	0.011
SDPR	serum deprivation response	0.011
RNASEK	ribonuclease, RNase K	0.011
MYLK	myosin light chain kinase	0.011
CALD1	caldesmon 1	0.011
APOF	apolipoprotein F	0.011
MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	0.011
B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.011
APOA2	apolipoprotein A-II	0.011
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.011
PLG	plasminogen	0.011	Human
SFTPD	surfactant protein D	0.011
AHSP	alpha hemoglobin stabilizing protein	0.011
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.011
SGSH	N-sulfoglucosamine sulfohydrolase	0.011
PKLR	pyruvate kinase, liver and RBC	0.011
EDN1	endothelin 1	0.011
FST	follistatin	0.011
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.011
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.011
MT1A	metallothionein 1A	0.011
ARRB2	arrestin, beta 2	0.011
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.011
PLIN2	perilipin 2	0.011
GJB5	gap junction protein, beta 5, 31.1kDa	0.011
FTCD	formiminotransferase cyclodeaminase	0.011
NID1	nidogen 1	0.011
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.011
HBQ1	hemoglobin, theta 1	0.011	Human
LBH	limb bud and heart development homolog (mouse)	0.011
NCF1	neutrophil cytosolic factor 1	0.011
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
EPS8	epidermal growth factor receptor pathway substrate 8	0.011
IGFBP5	insulin-like growth factor binding protein 5	0.011
RBBP7	retinoblastoma binding protein 7	0.011
C20orf20	chromosome 20 open reading frame 20	0.011
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.011
RIPK2	receptor-interacting serine-threonine kinase 2	0.011
RHOA	ras homolog gene family, member A	0.011	Human
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.011
PLTP	phospholipid transfer protein	0.011
TRAF3IP2	TRAF3 interacting protein 2	0.011
DOHH	deoxyhypusine hydroxylase/monooxygenase	0.011
TRADD	TNFRSF1A-associated via death domain	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011
ACTG2	actin, gamma 2, smooth muscle, enteric	0.011
CCDC90B	coiled-coil domain containing 90B	0.011
TF	transferrin	0.011
LITAF	lipopolysaccharide-induced TNF factor	0.011
C4BPB	complement component 4 binding protein, beta	0.011
CD40	CD40 molecule, TNF receptor superfamily member 5	0.011
ALPL	alkaline phosphatase, liver/bone/kidney	0.011
MUC1	mucin 1, cell surface associated	0.011
FADD	Fas (TNFRSF6)-associated via death domain	0.011
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.011
CAT	catalase	0.011
C19orf50	chromosome 19 open reading frame 50	0.011
BHMT	betaine--homocysteine S-methyltransferase	0.011
ITGB6	integrin, beta 6	0.011
CD36	CD36 molecule (thrombospondin receptor)	0.011	Mouse
GNAS	GNAS complex locus	0.011
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.011
RIPK3	receptor-interacting serine-threonine kinase 3	0.011
IRS2	insulin receptor substrate 2	0.011
TOP1	topoisomerase (DNA) I	0.010
CABP1	calcium binding protein 1	0.010
TGFBI	transforming growth factor, beta-induced, 68kDa	0.010
KRT81	keratin 81	0.010
PPARG	peroxisome proliferator-activated receptor gamma	0.010
HAGH	hydroxyacylglutathione hydrolase	0.010
CD46	CD46 molecule, complement regulatory protein	0.010
INSR	insulin receptor	0.010
ADAM17	ADAM metallopeptidase domain 17	0.010
RAD52	RAD52 homolog (S. cerevisiae)	0.010
HRG	histidine-rich glycoprotein	0.010
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.010	Human
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.010
MEF2A	myocyte enhancer factor 2A	0.010
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.010
LAMP1	lysosomal-associated membrane protein 1	0.010
KEL	Kell blood group, metallo-endopeptidase	0.010
MITF	microphthalmia-associated transcription factor	0.010
BANP	BTG3 associated nuclear protein	0.010
MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3	0.010
LBX1	ladybird homeobox 1	0.010
CTSG	cathepsin G	0.010
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.010	Human
ADH6	alcohol dehydrogenase 6 (class V)	0.010
H2AFY	H2A histone family, member Y	0.010
ACTC1	actin, alpha, cardiac muscle 1	0.010
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.010
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.010
ARG1	arginase, liver	0.010	Rat
CHD3	chromodomain helicase DNA binding protein 3	0.010
PIGR	polymeric immunoglobulin receptor	0.010
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.010	Human
SEPP1	selenoprotein P, plasma, 1	0.010
FOXP1	forkhead box P1	0.010
OSBP2	oxysterol binding protein 2	0.010
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.010
GM2A	GM2 ganglioside activator	0.010
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.010
H3F3A	H3 histone, family 3A	0.010
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.010
FKBP5	FK506 binding protein 5	0.010
PIR	pirin (iron-binding nuclear protein)	0.010
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.010
JAG1	jagged 1	0.010
XPO7	exportin 7	0.010
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.010
RDH16	retinol dehydrogenase 16 (all-trans)	0.010
SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	0.010
GHRHR	growth hormone releasing hormone receptor	0.010
TREH	trehalase (brush-border membrane glycoprotein)	0.010
C6orf25	chromosome 6 open reading frame 25	0.010
ECI2	enoyl-CoA delta isomerase 2	0.010
PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	0.010
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.010
BMI1	BMI1 polycomb ring finger oncogene	0.010
WDR83	WD repeat domain 83	0.010
RHOG	ras homolog gene family, member G (rho G)	0.010
OMP	olfactory marker protein	0.010
TGFB1	transforming growth factor, beta 1	0.010
MYO1B	myosin IB	0.010
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.010
PLXNB3	plexin B3	0.010
GSTP1	glutathione S-transferase pi 1	0.010
OGFOD2	2-oxoglutarate and iron-dependent oxygenase domain containing 2	0.010
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.010
CCL20	chemokine (C-C motif) ligand 20	0.010
ZMYM3	zinc finger, MYM-type 3	0.010
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.010