Process View
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "intrinsic apoptotic signaling pathway"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 1.000 | Human | |
TP53 | tumor protein p53 | 1.000 | ||
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 1.000 | ||
BCL2 | B-cell CLL/lymphoma 2 | 1.000 | ||
HDAC1 | histone deacetylase 1 | 0.999 | Mouse | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.999 | ||
BRCA1 | breast cancer 1, early onset | 0.999 | ||
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.998 | Human | |
UBC | ubiquitin C | 0.996 | ||
RB1 | retinoblastoma 1 | 0.995 | ||
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.994 | Human | |
ESR1 | estrogen receptor 1 | 0.993 | ||
MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.990 | ||
TP53BP2 | tumor protein p53 binding protein, 2 | 0.989 | ||
BCL2L1 | BCL2-like 1 | 0.983 | ||
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.979 | ||
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.976 | Human | |
NBN | nibrin | 0.973 | Mouse | |
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.970 | ||
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.969 | ||
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.968 | Human | |
SQSTM1 | sequestosome 1 | 0.968 | ||
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.957 | ||
EGFR | epidermal growth factor receptor | 0.954 | ||
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.953 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.948 | Mouse | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.948 | Human | |
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.947 | Mouse | |
XIAP | X-linked inhibitor of apoptosis | 0.946 | ||
EP300 | E1A binding protein p300 | 0.945 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.937 | ||
FAS | Fas (TNF receptor superfamily, member 6) | 0.937 | Human | |
RBL1 | retinoblastoma-like 1 (p107) | 0.927 | Fly | |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.918 | ||
CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.918 | ||
ATM | ataxia telangiectasia mutated | 0.916 | Mouse | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.913 | ||
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.905 | Human Mouse | |
SFN | stratifin | 0.904 | ||
BTRC | beta-transducin repeat containing | 0.903 | ||
PML | promyelocytic leukemia | 0.900 | ||
H2AFX | H2A histone family, member X | 0.893 | ||
BAX | BCL2-associated X protein | 0.871 | ||
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.871 | ||
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.866 | ||
DAXX | death-domain associated protein | 0.865 | ||
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.858 | ||
FADD | Fas (TNFRSF6)-associated via death domain | 0.849 | ||
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.841 | ||
CDK2 | cyclin-dependent kinase 2 | 0.839 | ||
PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.835 | ||
BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.834 | ||
RPS27 | ribosomal protein S27 | 0.833 | Human | |
SFPQ | splicing factor proline/glutamine-rich | 0.828 | ||
BID | BH3 interacting domain death agonist | 0.821 | ||
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.816 | Mouse | |
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.815 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.813 | ||
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.801 | ||
RYBP | RING1 and YY1 binding protein | 0.795 | ||
RBBP8 | retinoblastoma binding protein 8 | 0.793 | ||
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.779 | Human | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.772 | ||
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.765 | Human | |
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.753 | ||
ANXA1 | annexin A1 | 0.743 | ||
S100A4 | S100 calcium binding protein A4 | 0.736 | Human | |
FANCD2 | Fanconi anemia, complementation group D2 | 0.726 | ||
LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.720 | Fly | |
HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.719 | Mouse | |
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.714 | ||
TGIF1 | TGFB-induced factor homeobox 1 | 0.708 | ||
HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.705 | ||
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.704 | ||
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.700 | ||
E2F3 | E2F transcription factor 3 | 0.698 | Human | |
BIRC2 | baculoviral IAP repeat containing 2 | 0.698 | ||
HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.697 | ||
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.695 | ||
IER3 | immediate early response 3 | 0.674 | Mouse | |
CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.671 | Zebrafish | |
TRAF2 | TNF receptor-associated factor 2 | 0.654 | ||
TRADD | TNFRSF1A-associated via death domain | 0.652 | ||
RAD50 | RAD50 homolog (S. cerevisiae) | 0.647 | ||
S100A9 | S100 calcium binding protein A9 | 0.626 | ||
RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.624 | ||
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.617 | ||
DHX9 | DEAH (Asp-Glu-Ala-His) box polypeptide 9 | 0.595 | ||
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.594 | Human Mouse | |
UBE3A | ubiquitin protein ligase E3A | 0.582 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 0.581 | ||
TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.577 | Human | |
GSK3B | glycogen synthase kinase 3 beta | 0.571 | ||
OPTN | optineurin | 0.557 | ||
ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.550 | Mouse | |
CREBBP | CREB binding protein | 0.546 | Human | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.536 | ||
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.535 | ||
SOCS1 | suppressor of cytokine signaling 1 | 0.534 | ||
RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.528 | ||
CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.527 | ||
RBBP4 | retinoblastoma binding protein 4 | 0.525 | ||
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.524 | ||
S100A6 | S100 calcium binding protein A6 | 0.520 | Human | |
S100A8 | S100 calcium binding protein A8 | 0.510 | ||
ANXA2 | annexin A2 | 0.491 | ||
NCOA3 | nuclear receptor coactivator 3 | 0.490 | ||
VIM | vimentin | 0.487 | ||
NCK1 | NCK adaptor protein 1 | 0.478 | ||
MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.477 | ||
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.475 | ||
IL8 | interleukin 8 | 0.470 | ||
TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.455 | ||
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.434 | ||
TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.426 | Fly | |
E2F6 | E2F transcription factor 6 | 0.424 | Human | |
BMI1 | BMI1 polycomb ring finger oncogene | 0.415 | ||
TRAF1 | TNF receptor-associated factor 1 | 0.404 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.401 | Human | |
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.399 | ||
FYN | FYN oncogene related to SRC, FGR, YES | 0.397 | Human | |
RBL2 | retinoblastoma-like 2 (p130) | 0.395 | Fly | |
YY1 | YY1 transcription factor | 0.392 | ||
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.388 | ||
LCK | lymphocyte-specific protein tyrosine kinase | 0.379 | ||
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.379 | ||
ZNF746 | zinc finger protein 746 | 0.376 | ||
RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.375 | Worm | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.370 | ||
FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.369 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.367 | ||
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.365 | ||
GRB2 | growth factor receptor-bound protein 2 | 0.360 | ||
GRB7 | growth factor receptor-bound protein 7 | 0.357 | ||
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.353 | ||
MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.352 | ||
GUCY2C | guanylate cyclase 2C (heat stable enterotoxin receptor) | 0.352 | ||
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.347 | ||
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.342 | ||
NLRC4 | NLR family, CARD domain containing 4 | 0.340 | ||
CDK6 | cyclin-dependent kinase 6 | 0.338 | ||
APAF1 | apoptotic peptidase activating factor 1 | 0.337 | ||
SYK | spleen tyrosine kinase | 0.330 | ||
PCNA | proliferating cell nuclear antigen | 0.324 | ||
REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.324 | ||
E2F4 | E2F transcription factor 4, p107/p130-binding | 0.321 | Human | |
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.319 | ||
TFDP1 | transcription factor Dp-1 | 0.319 | Fly | |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.317 | ||
PTEN | phosphatase and tensin homolog | 0.317 | ||
BCL3 | B-cell CLL/lymphoma 3 | 0.315 | ||
CCND1 | cyclin D1 | 0.310 | ||
ICAM1 | intercellular adhesion molecule 1 | 0.303 | ||
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.302 | ||
VCP | valosin containing protein | 0.300 | ||
SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.297 | ||
DERL1 | Der1-like domain family, member 1 | 0.297 | ||
S100A14 | S100 calcium binding protein A14 | 0.293 | ||
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.291 | ||
NAMPT | nicotinamide phosphoribosyltransferase | 0.288 | ||
LIN9 | lin-9 homolog (C. elegans) | 0.287 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.286 | ||
SNIP1 | Smad nuclear interacting protein 1 | 0.284 | ||
SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.284 | ||
EGR1 | early growth response 1 | 0.277 | ||
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.271 | Human | |
MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 0.270 | Mouse Worm | |
WBP4 | WW domain binding protein 4 (formin binding protein 21) | 0.266 | ||
BCAP31 | B-cell receptor-associated protein 31 | 0.261 | ||
SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.257 | ||
DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.255 | ||
HIC2 | hypermethylated in cancer 2 | 0.255 | Human | |
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.253 | ||
JUN | jun proto-oncogene | 0.253 | ||
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.252 | Human | |
KAT2B | K(lysine) acetyltransferase 2B | 0.251 | ||
CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.249 | ||
TOP1 | topoisomerase (DNA) I | 0.248 | ||
SKP2 | S-phase kinase-associated protein 2 (p45) | 0.246 | ||
RUNX1 | runt-related transcription factor 1 | 0.243 | ||
BAK1 | BCL2-antagonist/killer 1 | 0.242 | Human | |
GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.241 | ||
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.238 | ||
DDIT3 | DNA-damage-inducible transcript 3 | 0.237 | ||
PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.234 | ||
DDX5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 0.234 | ||
CASC5 | cancer susceptibility candidate 5 | 0.234 | ||
NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.233 | ||
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.229 | ||
FAM162A | family with sequence similarity 162, member A | 0.224 | ||
EFNA1 | ephrin-A1 | 0.222 | ||
MED1 | mediator complex subunit 1 | 0.222 | ||
MOBKL1B | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.220 | ||
BLNK | B-cell linker | 0.219 | ||
SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.218 | Mouse | |
LASS2 | LAG1 homolog, ceramide synthase 2 | 0.217 | ||
LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.216 | ||
SEPT2 | septin 2 | 0.215 | Human | |
PLK1 | polo-like kinase 1 | 0.214 | ||
HIC1 | hypermethylated in cancer 1 | 0.211 | ||
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.208 | ||
VEGFA | vascular endothelial growth factor A | 0.208 | ||
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.205 | ||
RPS18 | ribosomal protein S18 | 0.204 | ||
MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 0.203 | Mouse | |
S100A10 | S100 calcium binding protein A10 | 0.201 | Human | |
CCND3 | cyclin D3 | 0.201 | ||
PARP1 | poly (ADP-ribose) polymerase 1 | 0.201 | ||
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.200 | ||
CDK9 | cyclin-dependent kinase 9 | 0.197 | ||
BHLHE40 | basic helix-loop-helix family, member e40 | 0.196 | ||
PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.195 | ||
STX5 | syntaxin 5 | 0.194 | ||
PRDX2 | peroxiredoxin 2 | 0.192 | ||
YAP1 | Yes-associated protein 1 | 0.189 | ||
HUWE1 | HECT, UBA and WWE domain containing 1 | 0.188 | ||
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.188 | Mouse | |
HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.183 | ||
UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 0.180 | ||
HUS1 | HUS1 checkpoint homolog (S. pombe) | 0.180 | ||
E2F1 | E2F transcription factor 1 | 0.180 | ||
CDK4 | cyclin-dependent kinase 4 | 0.180 | ||
KEAP1 | kelch-like ECH-associated protein 1 | 0.179 | ||
MSH6 | mutS homolog 6 (E. coli) | 0.178 | Mouse | |
DAZAP2 | DAZ associated protein 2 | 0.177 | ||
BAD | BCL2-associated agonist of cell death | 0.177 | ||
NOTCH1 | notch 1 | 0.176 | ||
MAPK6 | mitogen-activated protein kinase 6 | 0.175 | ||
RBBP7 | retinoblastoma binding protein 7 | 0.174 | ||
LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.172 | ||
ERO1L | ERO1-like (S. cerevisiae) | 0.169 | Mouse | |
RAD18 | RAD18 homolog (S. cerevisiae) | 0.168 | ||
SNW1 | SNW domain containing 1 | 0.167 | ||
HCK | hemopoietic cell kinase | 0.165 | Human | |
BCL6 | B-cell CLL/lymphoma 6 | 0.165 | Zebrafish | |
MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.163 | ||
TNF | tumor necrosis factor | 0.163 | ||
UBQLN4 | ubiquilin 4 | 0.162 | Human | |
AHR | aryl hydrocarbon receptor | 0.160 | ||
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.160 | ||
RAD17 | RAD17 homolog (S. pombe) | 0.159 | ||
SPRR2A | small proline-rich protein 2A | 0.157 | ||
PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.157 | ||
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.156 | ||
TRIB3 | tribbles homolog 3 (Drosophila) | 0.153 | ||
RPL39 | ribosomal protein L39 | 0.152 | ||
PDIA3 | protein disulfide isomerase family A, member 3 | 0.150 | ||
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.148 | ||
SKP1 | S-phase kinase-associated protein 1 | 0.147 | ||
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.147 | ||
BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.145 | Human | |
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.145 | ||
RIN1 | Ras and Rab interactor 1 | 0.145 | ||
EZR | ezrin | 0.143 | ||
RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.143 | ||
TNIP2 | TNFAIP3 interacting protein 2 | 0.142 | ||
STRADA | STE20-related kinase adaptor alpha | 0.141 | ||
PDCD6IP | programmed cell death 6 interacting protein | 0.141 | ||
DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.139 | ||
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.139 | Human | |
ACTB | actin, beta | 0.139 | ||
CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.139 | ||
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.138 | ||
NONO | non-POU domain containing, octamer-binding | 0.137 | ||
SLC3A2 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 0.137 | ||
CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.134 | ||
GADD45B | growth arrest and DNA-damage-inducible, beta | 0.134 | ||
SEPT11 | septin 11 | 0.132 | ||
MAPK1 | mitogen-activated protein kinase 1 | 0.132 | ||
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.131 | ||
PDIA4 | protein disulfide isomerase family A, member 4 | 0.131 | ||
SRGN | serglycin | 0.131 | ||
CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.130 | Human | |
IRF1 | interferon regulatory factor 1 | 0.129 | ||
DAD1 | defender against cell death 1 | 0.128 | ||
HIPK2 | homeodomain interacting protein kinase 2 | 0.127 | Mouse | |
NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 0.127 | ||
HDAC6 | histone deacetylase 6 | 0.127 | ||
S100A2 | S100 calcium binding protein A2 | 0.127 | Human | |
BCR | breakpoint cluster region | 0.126 | ||
FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.125 | ||
COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.124 | ||
SP1 | Sp1 transcription factor | 0.124 | ||
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.122 | ||
MSH3 | mutS homolog 3 (E. coli) | 0.121 | ||
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.121 | ||
STK24 | serine/threonine kinase 24 | 0.121 | ||
PLSCR1 | phospholipid scramblase 1 | 0.119 | Mouse | |
PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.118 | ||
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.118 | ||
PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.116 | Human | |
UBASH3B | ubiquitin associated and SH3 domain containing B | 0.115 | ||
WWOX | WW domain containing oxidoreductase | 0.114 | ||
CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.112 | ||
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.112 | ||
EGLN1 | egl nine homolog 1 (C. elegans) | 0.111 | ||
S100B | S100 calcium binding protein B | 0.109 | Human | |
SP100 | SP100 nuclear antigen | 0.107 | ||
LZTS2 | leucine zipper, putative tumor suppressor 2 | 0.107 | ||
DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.106 | ||
MSN | moesin | 0.106 | ||
HSPA1L | heat shock 70kDa protein 1-like | 0.105 | ||
S100A11 | S100 calcium binding protein A11 | 0.105 | Human | |
NUF2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.104 | ||
CA12 | carbonic anhydrase XII | 0.104 | ||
ATF3 | activating transcription factor 3 | 0.104 | ||
PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.103 | ||
RNF5 | ring finger protein 5 | 0.103 | ||
MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.103 | ||
CANX | calnexin | 0.103 | ||
BIK | BCL2-interacting killer (apoptosis-inducing) | 0.103 | ||
RHOXF2 | Rhox homeobox family, member 2 | 0.103 | ||
MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.103 | ||
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.103 | Human | |
ATR | ataxia telangiectasia and Rad3 related | 0.102 | ||
EFNA5 | ephrin-A5 | 0.102 | ||
MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.102 | ||
KRT5 | keratin 5 | 0.102 | ||
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.101 | ||
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.101 | ||
HSPA8 | heat shock 70kDa protein 8 | 0.099 | ||
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.099 | ||
RAD21 | RAD21 homolog (S. pombe) | 0.098 | ||
PLAUR | plasminogen activator, urokinase receptor | 0.098 | ||
PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.097 | ||
EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.097 | ||
SEPT7 | septin 7 | 0.096 | Human | |
KIAA1524 | KIAA1524 | 0.096 | ||
SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.096 | Human | |
CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.095 | ||
CUL3 | cullin 3 | 0.094 | ||
HIPK1 | homeodomain interacting protein kinase 1 | 0.094 | Mouse | |
FASLG | Fas ligand (TNF superfamily, member 6) | 0.094 | ||
AHNAK | AHNAK nucleoprotein | 0.094 | ||
SMARCAD1 | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 | 0.093 | ||
UBQLN1 | ubiquilin 1 | 0.092 | ||
PTPRF | protein tyrosine phosphatase, receptor type, F | 0.092 | ||
AREG | amphiregulin | 0.091 | ||
POLH | polymerase (DNA directed), eta | 0.091 | ||
ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.090 | ||
SMCR7L | Smith-Magenis syndrome chromosome region, candidate 7-like | 0.089 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.088 | ||
FEM1B | fem-1 homolog b (C. elegans) | 0.088 | ||
PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.088 | Human | |
OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.087 | ||
SGOL2 | shugoshin-like 2 (S. pombe) | 0.087 | ||
CARD11 | caspase recruitment domain family, member 11 | 0.085 | ||
SON | SON DNA binding protein | 0.084 | ||
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.083 | ||
GCH1 | GTP cyclohydrolase 1 | 0.083 | ||
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.083 | ||
PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) | 0.083 | ||
FAM101B | family with sequence similarity 101, member B | 0.083 | ||
RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.082 | ||
VHL | von Hippel-Lindau tumor suppressor | 0.082 | ||
STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.082 | ||
TLR2 | toll-like receptor 2 | 0.081 | ||
ZNF512B | zinc finger protein 512B | 0.080 | ||
DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | 0.080 | Human | |
SNAI1 | snail homolog 1 (Drosophila) | 0.080 | ||
RPS10 | ribosomal protein S10 | 0.080 | ||
CSTA | cystatin A (stefin A) | 0.080 | ||
CAPRIN1 | cell cycle associated protein 1 | 0.080 | ||
SEPT6 | septin 6 | 0.080 | ||
SOCS3 | suppressor of cytokine signaling 3 | 0.079 | ||
TRIM27 | tripartite motif containing 27 | 0.079 | ||
RAD23B | RAD23 homolog B (S. cerevisiae) | 0.079 | ||
CUL2 | cullin 2 | 0.079 | ||
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.078 | ||
IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.078 | ||
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.078 | ||
FOSL1 | FOS-like antigen 1 | 0.077 | ||
CDCA2 | cell division cycle associated 2 | 0.077 | ||
HMOX2 | heme oxygenase (decycling) 2 | 0.077 | ||
SIRT1 | sirtuin 1 | 0.076 | ||
RPA1 | replication protein A1, 70kDa | 0.076 | ||
BCL10 | B-cell CLL/lymphoma 10 | 0.075 | ||
SMCR7 | Smith-Magenis syndrome chromosome region, candidate 7 | 0.075 | ||
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.074 | ||
EGLN3 | egl nine homolog 3 (C. elegans) | 0.074 | ||
NMI | N-myc (and STAT) interactor | 0.074 | ||
HK2 | hexokinase 2 | 0.073 | ||
AMOT | angiomotin | 0.073 | ||
LMNA | lamin A/C | 0.073 | ||
IFNGR1 | interferon gamma receptor 1 | 0.073 | ||
PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.073 | ||
PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.072 | ||
NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.072 | ||
SESN2 | sestrin 2 | 0.072 | ||
IL1B | interleukin 1, beta | 0.072 | ||
HDAC2 | histone deacetylase 2 | 0.071 | Mouse | |
BABAM1 | BRISC and BRCA1 A complex member 1 | 0.071 | ||
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.070 | ||
TXNIP | thioredoxin interacting protein | 0.070 | ||
NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.069 | Human | |
STRN3 | striatin, calmodulin binding protein 3 | 0.069 | ||
BCL2L2 | BCL2-like 2 | 0.069 | Human | |
PLCG1 | phospholipase C, gamma 1 | 0.069 | ||
CD44 | CD44 molecule (Indian blood group) | 0.069 | ||
RFC1 | replication factor C (activator 1) 1, 145kDa | 0.068 | ||
MT1A | metallothionein 1A | 0.068 | ||
PRDX6 | peroxiredoxin 6 | 0.068 | ||
CUL1 | cullin 1 | 0.067 | ||
AURKB | aurora kinase B | 0.067 | ||
RPS12 | ribosomal protein S12 | 0.067 | ||
KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.067 | ||
CTBP1 | C-terminal binding protein 1 | 0.067 | ||
MAVS | mitochondrial antiviral signaling protein | 0.067 | ||
CLSPN | claspin | 0.065 | ||
HLTF | helicase-like transcription factor | 0.065 | ||
RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.065 | ||
BTG1 | B-cell translocation gene 1, anti-proliferative | 0.065 | ||
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.065 | ||
PPP6C | protein phosphatase 6, catalytic subunit | 0.065 | ||
DDX17 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 0.065 | Human | |
TBC1D17 | TBC1 domain family, member 17 | 0.065 | ||
PRDX1 | peroxiredoxin 1 | 0.064 | ||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.064 | ||
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.064 | ||
EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.064 | ||
PDCD10 | programmed cell death 10 | 0.064 | ||
USP11 | ubiquitin specific peptidase 11 | 0.063 | ||
BBC3 | BCL2 binding component 3 | 0.063 | ||
CTBP2 | C-terminal binding protein 2 | 0.063 | ||
FUS | fused in sarcoma | 0.063 | ||
KLF5 | Kruppel-like factor 5 (intestinal) | 0.063 | ||
DAB2IP | DAB2 interacting protein | 0.062 | Mouse | |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.062 | ||
MZT2A | mitotic spindle organizing protein 2A | 0.062 | ||
ATAD2 | ATPase family, AAA domain containing 2 | 0.062 | ||
ATF5 | activating transcription factor 5 | 0.062 | ||
ASB2 | ankyrin repeat and SOCS box containing 2 | 0.062 | ||
STK25 | serine/threonine kinase 25 | 0.062 | Human | |
EIF4E | eukaryotic translation initiation factor 4E | 0.062 | ||
HSPB1 | heat shock 27kDa protein 1 | 0.062 | Mouse | |
H2AFV | H2A histone family, member V | 0.062 | ||
SH3RF1 | SH3 domain containing ring finger 1 | 0.062 | ||
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.061 | ||
MEFV | Mediterranean fever | 0.061 | ||
AR | androgen receptor | 0.061 | ||
SPDEF | SAM pointed domain containing ets transcription factor | 0.061 | ||
SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.061 | ||
CYBA | cytochrome b-245, alpha polypeptide | 0.061 | ||
TBC1D10A | TBC1 domain family, member 10A | 0.061 | ||
PSEN1 | presenilin 1 | 0.061 | ||
FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.060 | Human | |
OPA1 | optic atrophy 1 (autosomal dominant) | 0.060 | ||
EIF1 | eukaryotic translation initiation factor 1 | 0.060 | ||
EGF | epidermal growth factor | 0.060 | ||
MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.060 | ||
LIN28B | lin-28 homolog B (C. elegans) | 0.060 | ||
VDAC1 | voltage-dependent anion channel 1 | 0.060 | ||
TUBA1A | tubulin, alpha 1a | 0.060 | ||
EED | embryonic ectoderm development | 0.059 | ||
BAG5 | BCL2-associated athanogene 5 | 0.059 | ||
LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.059 | ||
EXO1 | exonuclease 1 | 0.059 | ||
COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | 0.059 | ||
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.058 | ||
CHD1 | chromodomain helicase DNA binding protein 1 | 0.058 | ||
RANBP2 | RAN binding protein 2 | 0.058 | ||
SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.058 | ||
SPOP | speckle-type POZ protein | 0.057 | Mouse | |
SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.057 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.057 | ||
BLM | Bloom syndrome, RecQ helicase-like | 0.057 | ||
APP | amyloid beta (A4) precursor protein | 0.057 | ||
PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.056 | ||
FKBP8 | FK506 binding protein 8, 38kDa | 0.056 | ||
PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 0.056 | ||
C17orf79 | chromosome 17 open reading frame 79 | 0.056 | ||
FES | feline sarcoma oncogene | 0.056 | ||
TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.055 | ||
SMC2 | structural maintenance of chromosomes 2 | 0.055 | ||
RPL41 | ribosomal protein L41 | 0.055 | ||
UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.055 | ||
UPP1 | uridine phosphorylase 1 | 0.055 | ||
SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.055 | ||
E2F2 | E2F transcription factor 2 | 0.054 | Human Mouse | |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.054 | ||
ADM | adrenomedullin | 0.054 | ||
PCGF6 | polycomb group ring finger 6 | 0.054 | ||
MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.054 | ||
HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.054 | ||
HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.054 | ||
NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.053 | ||
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.053 | ||
ZBTB16 | zinc finger and BTB domain containing 16 | 0.053 | ||
PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.053 | ||
S100P | S100 calcium binding protein P | 0.053 | Human | |
ITK | IL2-inducible T-cell kinase | 0.053 | ||
PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 0.053 | ||
ETS1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.053 | ||
STK4 | serine/threonine kinase 4 | 0.053 | ||
TRAP1 | TNF receptor-associated protein 1 | 0.053 | ||
ARNT | aryl hydrocarbon receptor nuclear translocator | 0.053 | ||
FBXO33 | F-box protein 33 | 0.053 | ||
MARK4 | MAP/microtubule affinity-regulating kinase 4 | 0.052 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.052 | ||
IK | IK cytokine, down-regulator of HLA II | 0.052 | ||
MTA1 | metastasis associated 1 | 0.052 | ||
MYST1 | MYST histone acetyltransferase 1 | 0.052 | ||
CRYAB | crystallin, alpha B | 0.052 | ||
DCTN3 | dynactin 3 (p22) | 0.052 | ||
SETDB1 | SET domain, bifurcated 1 | 0.052 | ||
DIABLO | diablo, IAP-binding mitochondrial protein | 0.052 | ||
PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.052 | ||
TNS4 | tensin 4 | 0.051 | ||
SNX17 | sorting nexin 17 | 0.051 | ||
FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.051 | ||
CDK1 | cyclin-dependent kinase 1 | 0.051 | ||
TPR | translocated promoter region (to activated MET oncogene) | 0.051 | ||
PF4 | platelet factor 4 | 0.051 | ||
MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.051 | ||
USP2 | ubiquitin specific peptidase 2 | 0.051 | ||
NRG1 | neuregulin 1 | 0.051 | ||
CCNE1 | cyclin E1 | 0.050 | ||
CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.050 | ||
CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.050 | ||
RING1 | ring finger protein 1 | 0.050 | ||
PEA15 | phosphoprotein enriched in astrocytes 15 | 0.050 | ||
TMSB4X | thymosin beta 4, X-linked | 0.050 | ||
TMEM147 | transmembrane protein 147 | 0.050 | ||
FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.050 | ||
THRAP3 | thyroid hormone receptor associated protein 3 | 0.050 | ||
SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.050 | ||
VEZF1 | vascular endothelial zinc finger 1 | 0.049 | ||
SMC3 | structural maintenance of chromosomes 3 | 0.049 | ||
CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.049 | ||
NHP2 | NHP2 ribonucleoprotein homolog (yeast) | 0.049 | ||
EPAS1 | endothelial PAS domain protein 1 | 0.049 | Human | |
DBNDD2 | dysbindin (dystrobrevin binding protein 1) domain containing 2 | 0.049 | ||
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.049 | ||
TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.049 | Mouse | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.049 | ||
NCL | nucleolin | 0.049 | ||
PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.049 | ||
AMOTL1 | angiomotin like 1 | 0.049 | ||
BRCA2 | breast cancer 2, early onset | 0.049 | Mouse | |
JAK3 | Janus kinase 3 | 0.048 | ||
MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.048 | ||
CCL20 | chemokine (C-C motif) ligand 20 | 0.048 | ||
RRM1 | ribonucleotide reductase M1 | 0.048 | ||
CD320 | CD320 molecule | 0.048 | ||
BAG1 | BCL2-associated athanogene | 0.048 | ||
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.048 | ||
PURA | purine-rich element binding protein A | 0.047 | ||
BANP | BTG3 associated nuclear protein | 0.047 | ||
SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.047 | ||
ETF1 | eukaryotic translation termination factor 1 | 0.047 | ||
UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.047 | ||
ZFYVE1 | zinc finger, FYVE domain containing 1 | 0.047 | ||
GRB10 | growth factor receptor-bound protein 10 | 0.047 | ||
ISOC2 | isochorismatase domain containing 2 | 0.046 | ||
TIFA | TRAF-interacting protein with forkhead-associated domain | 0.046 | ||
MEF2C | myocyte enhancer factor 2C | 0.046 | ||
MKRN1 | makorin ring finger protein 1 | 0.046 | ||
ARIH2 | ariadne homolog 2 (Drosophila) | 0.046 | ||
CRIP1 | cysteine-rich protein 1 (intestinal) | 0.046 | ||
ESCO2 | establishment of cohesion 1 homolog 2 (S. cerevisiae) | 0.046 | ||
ANKRD32 | ankyrin repeat domain 32 | 0.046 | ||
ANLN | anillin, actin binding protein | 0.046 | ||
MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.046 | ||
SH3BP2 | SH3-domain binding protein 2 | 0.046 | ||
RFWD2 | ring finger and WD repeat domain 2 | 0.046 | ||
RAD54B | RAD54 homolog B (S. cerevisiae) | 0.045 | ||
NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.045 | ||
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | 0.045 | ||
PRKCE | protein kinase C, epsilon | 0.045 | ||
CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.045 | ||
MEN1 | multiple endocrine neoplasia I | 0.045 | ||
HSPB8 | heat shock 22kDa protein 8 | 0.045 | ||
ZFAND5 | zinc finger, AN1-type domain 5 | 0.045 | ||
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.045 | ||
MYOD1 | myogenic differentiation 1 | 0.045 | ||
PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.044 | ||
PHB | prohibitin | 0.044 | ||
KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.044 | ||
DOK4 | docking protein 4 | 0.044 | ||
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.044 | ||
CCDC6 | coiled-coil domain containing 6 | 0.044 | ||
PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.044 | ||
HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.044 | ||
PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.044 | ||
WDR6 | WD repeat domain 6 | 0.044 | ||
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.044 | ||
RPLP1 | ribosomal protein, large, P1 | 0.044 | ||
SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.044 | ||
EPOR | erythropoietin receptor | 0.044 | ||
VAV2 | vav 2 guanine nucleotide exchange factor | 0.043 | ||
MSH5 | mutS homolog 5 (E. coli) | 0.043 | ||
ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.043 | ||
EPHA8 | EPH receptor A8 | 0.043 | Human | |
COMMD4 | COMM domain containing 4 | 0.043 | ||
MRPS24 | mitochondrial ribosomal protein S24 | 0.043 | ||
S100A1 | S100 calcium binding protein A1 | 0.043 | Human | |
NCOR2 | nuclear receptor corepressor 2 | 0.043 | ||
IL1R1 | interleukin 1 receptor, type I | 0.043 | ||
GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.043 | ||
PRDX4 | peroxiredoxin 4 | 0.043 | ||
LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.043 | ||
WRN | Werner syndrome, RecQ helicase-like | 0.042 | ||
DPP4 | dipeptidyl-peptidase 4 | 0.042 | ||
PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.042 | ||
SATB2 | SATB homeobox 2 | 0.042 | ||
PPHLN1 | periphilin 1 | 0.042 | ||
NDUFB11 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa | 0.042 | ||
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.042 | ||
SPRY2 | sprouty homolog 2 (Drosophila) | 0.042 | ||
SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.042 | ||
PTPLAD1 | protein tyrosine phosphatase-like A domain containing 1 | 0.042 | ||
KYNU | kynureninase | 0.042 | ||
FAM190B | family with sequence similarity 190, member B | 0.041 | ||
DCAF7 | DDB1 and CUL4 associated factor 7 | 0.041 | ||
MAGEH1 | melanoma antigen family H, 1 | 0.041 | ||
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 0.041 | ||
MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.041 | ||
SGOL1 | shugoshin-like 1 (S. pombe) | 0.041 | ||
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.041 | ||
TUBB | tubulin, beta | 0.041 | ||
COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.041 | ||
RAB21 | RAB21, member RAS oncogene family | 0.041 | ||
BCL2A1 | BCL2-related protein A1 | 0.041 | Human | |
RPS14 | ribosomal protein S14 | 0.041 | ||
APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.041 | ||
DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.040 | Human | |
TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.040 | ||
RPS15 | ribosomal protein S15 | 0.040 | ||
UBL5 | ubiquitin-like 5 | 0.040 | ||
NFIL3 | nuclear factor, interleukin 3 regulated | 0.040 | ||
PCDH9 | protocadherin 9 | 0.040 | ||
CD59 | CD59 molecule, complement regulatory protein | 0.040 | ||
RXRB | retinoid X receptor, beta | 0.040 | ||
MIS18BP1 | MIS18 binding protein 1 | 0.040 | ||
SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.040 | ||
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.039 | ||
TMSB10 | thymosin beta 10 | 0.039 | ||
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 | 0.039 | ||
FAM40B | family with sequence similarity 40, member B | 0.039 | ||
NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | 0.039 | ||
TDGF1 | teratocarcinoma-derived growth factor 1 | 0.039 | ||
PRKCB | protein kinase C, beta | 0.039 | ||
PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.039 | ||
IL6 | interleukin 6 (interferon, beta 2) | 0.039 | ||
BARD1 | BRCA1 associated RING domain 1 | 0.039 | ||
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.039 | ||
MAX | MYC associated factor X | 0.039 | ||
HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.039 | ||
INHBA | inhibin, beta A | 0.039 | ||
TGFA | transforming growth factor, alpha | 0.039 | ||
MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.039 | ||
CAND1 | cullin-associated and neddylation-dissociated 1 | 0.039 | ||
CAV2 | caveolin 2 | 0.038 | Human | |
ROMO1 | reactive oxygen species modulator 1 | 0.038 | ||
RARA | retinoic acid receptor, alpha | 0.038 | ||
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.038 | ||
UBXN4 | UBX domain protein 4 | 0.038 | ||
EIF2C2 | eukaryotic translation initiation factor 2C, 2 | 0.038 | ||
MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.038 | ||
STRADB | STE20-related kinase adaptor beta | 0.038 | ||
CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.038 | ||
NDUFA11 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 0.038 | ||
USP42 | ubiquitin specific peptidase 42 | 0.038 | ||
SPC24 | SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.038 | ||
DMPK | dystrophia myotonica-protein kinase | 0.038 | ||
S100A12 | S100 calcium binding protein A12 | 0.037 | Human | |
MAGEA2 | melanoma antigen family A, 2 | 0.037 | ||
RAD1 | RAD1 homolog (S. pombe) | 0.037 | Worm | |
HELLS | helicase, lymphoid-specific | 0.037 | Mouse | |
ARF6 | ADP-ribosylation factor 6 | 0.037 | ||
MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.037 | ||
MYST2 | MYST histone acetyltransferase 2 | 0.037 | ||
RPLP2 | ribosomal protein, large, P2 | 0.037 | ||
NEDD1 | neural precursor cell expressed, developmentally down-regulated 1 | 0.037 | ||
SAP18 | Sin3A-associated protein, 18kDa | 0.037 | ||
PPP1R15B | protein phosphatase 1, regulatory (inhibitor) subunit 15B | 0.037 | ||
LRDD | leucine-rich repeats and death domain containing | 0.037 | ||
YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.037 | Human | |
ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.037 | ||
LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.037 | ||
PRDX5 | peroxiredoxin 5 | 0.037 | ||
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.037 | ||
TCAP | titin-cap (telethonin) | 0.037 | ||
CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.037 | ||
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.036 | ||
PALB2 | partner and localizer of BRCA2 | 0.036 | ||
UXT | ubiquitously-expressed transcript | 0.036 | ||
ING2 | inhibitor of growth family, member 2 | 0.036 | ||
NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 0.036 | ||
PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.036 | ||
STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.036 | ||
JUB | jub, ajuba homolog (Xenopus laevis) | 0.036 | ||
HRK | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.036 | ||
PIAS1 | protein inhibitor of activated STAT, 1 | 0.036 | ||
GRPEL1 | GrpE-like 1, mitochondrial (E. coli) | 0.036 | ||
PEBP1 | phosphatidylethanolamine binding protein 1 | 0.036 | ||
TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.035 | ||
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.035 | ||
PTK2 | PTK2 protein tyrosine kinase 2 | 0.035 | ||
TCF19 | transcription factor 19 | 0.035 | ||
PRKCA | protein kinase C, alpha | 0.035 | Mouse | |
PI3 | peptidase inhibitor 3, skin-derived | 0.035 | ||
USP28 | ubiquitin specific peptidase 28 | 0.035 | ||
RB1CC1 | RB1-inducible coiled-coil 1 | 0.035 | ||
TUBB6 | tubulin, beta 6 | 0.035 | ||
TXN | thioredoxin | 0.035 | ||
C19orf53 | chromosome 19 open reading frame 53 | 0.035 | ||
PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.035 | ||
CBX4 | chromobox homolog 4 | 0.035 | ||
DBP | D site of albumin promoter (albumin D-box) binding protein | 0.035 | ||
NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.035 | ||
ALAS1 | aminolevulinate, delta-, synthase 1 | 0.035 | ||
PCGF3 | polycomb group ring finger 3 | 0.035 | ||
MDC1 | mediator of DNA-damage checkpoint 1 | 0.035 | ||
FOXM1 | forkhead box M1 | 0.035 | ||
IFI16 | interferon, gamma-inducible protein 16 | 0.035 | ||
PFKL | phosphofructokinase, liver | 0.035 | ||
PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.035 | ||
TUBA3C | tubulin, alpha 3c | 0.034 | ||
RIF1 | RAP1 interacting factor homolog (yeast) | 0.034 | ||
CD14 | CD14 molecule | 0.034 | ||
PRKCDBP | protein kinase C, delta binding protein | 0.034 | ||
LATS1 | LATS, large tumor suppressor, homolog 1 (Drosophila) | 0.034 | Fly | |
USP15 | ubiquitin specific peptidase 15 | 0.034 | ||
EPRS | glutamyl-prolyl-tRNA synthetase | 0.034 | ||
MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.034 | ||
HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.034 | ||
SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.034 | ||
CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.034 | ||
DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 0.034 | Human | |
ZWINT | ZW10 interactor | 0.034 | ||
NSL1 | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.034 | ||
GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.034 | ||
YRDC | yrdC domain containing (E. coli) | 0.034 | ||
USP25 | ubiquitin specific peptidase 25 | 0.034 | Human | |
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.033 | ||
MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.033 | ||
TTC3 | tetratricopeptide repeat domain 3 | 0.033 | ||
TSPYL4 | TSPY-like 4 | 0.033 | ||
C19orf70 | chromosome 19 open reading frame 70 | 0.033 | ||
NIT2 | nitrilase family, member 2 | 0.033 | ||
MNAT1 | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 0.033 | ||
FAM46A | family with sequence similarity 46, member A | 0.033 | ||
DICER1 | dicer 1, ribonuclease type III | 0.033 | ||
TBK1 | TANK-binding kinase 1 | 0.033 | Human | |
GLRX | glutaredoxin (thioltransferase) | 0.033 | ||
MARK1 | MAP/microtubule affinity-regulating kinase 1 | 0.033 | ||
HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | 0.033 | ||
RFC3 | replication factor C (activator 1) 3, 38kDa | 0.033 | ||
MLKL | mixed lineage kinase domain-like | 0.033 |