IMP: Integrative Multi-species Prediction

Homo sapiens

18 genes annotated in human

Multi-species View

metaphase plate congression

GO:0051310

The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "metaphase plate congression"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "metaphase plate congression" (in gray)

Name	Description	Probability	Func Analog Organism
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.799
CCNB1	cyclin B1	0.518
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.445
NUP107	nucleoporin 107kDa	0.344
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.296
INCENP	inner centromere protein antigens 135/155kDa	0.278
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.253
RACGAP1	Rac GTPase activating protein 1	0.207
CENPE	centromere protein E, 312kDa	0.201
RB1	retinoblastoma 1	0.198
AURKB	aurora kinase B	0.192
CCNA2	cyclin A2	0.163
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.147
PARP1	poly (ADP-ribose) polymerase 1	0.136
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.131	Fly
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.115
AHCTF1	AT hook containing transcription factor 1	0.114
NUP133	nucleoporin 133kDa	0.111
CENPF	centromere protein F, 350/400kDa (mitosin)	0.107
CDK2	cyclin-dependent kinase 2	0.104
CKAP5	cytoskeleton associated protein 5	0.101
KIF20A	kinesin family member 20A	0.094
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.087
CDK1	cyclin-dependent kinase 1	0.082
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.074
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.069
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.064
CBX5	chromobox homolog 5	0.063
ZWINT	ZW10 interactor	0.063
PRC1	protein regulator of cytokinesis 1	0.062
KIF23	kinesin family member 23	0.062
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.062
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.060
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.060
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.059
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.056
SGOL2	shugoshin-like 2 (S. pombe)	0.049
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.048
NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.044
BLM	Bloom syndrome, RecQ helicase-like	0.043
NOLC1	nucleolar and coiled-body phosphoprotein 1	0.043
LBR	lamin B receptor	0.040
BIRC5	baculoviral IAP repeat containing 5	0.039
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.039
MIS18BP1	MIS18 binding protein 1	0.037
C13orf34	chromosome 13 open reading frame 34	0.037
NUF2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.036
SGOL1	shugoshin-like 1 (S. pombe)	0.036
KIF1B	kinesin family member 1B	0.035
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.035
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.034
CCNE1	cyclin E1	0.033
FBXO5	F-box protein 5	0.033
OPA1	optic atrophy 1 (autosomal dominant)	0.033
CCNE2	cyclin E2	0.032
XPO1	exportin 1 (CRM1 homolog, yeast)	0.032
GPSM2	G-protein signaling modulator 2	0.031
BRCA1	breast cancer 1, early onset	0.031
NUP43	nucleoporin 43kDa	0.031
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.030
CEP55	centrosomal protein 55kDa	0.029
RBL1	retinoblastoma-like 1 (p107)	0.029	Human
CCNB2	cyclin B2	0.029	Human
KIF11	kinesin family member 11	0.028
PPP1R8	protein phosphatase 1, regulatory (inhibitor) subunit 8	0.027
PHAX	phosphorylated adaptor for RNA export	0.025
CASC5	cancer susceptibility candidate 5	0.025
NCAPG	non-SMC condensin I complex, subunit G	0.025
YTHDC2	YTH domain containing 2	0.024
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.023
MSH6	mutS homolog 6 (E. coli)	0.023
ECT2	epithelial cell transforming sequence 2 oncogene	0.022
NCAPH	non-SMC condensin I complex, subunit H	0.022
BRCA2	breast cancer 2, early onset	0.021
PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.020
E2F5	E2F transcription factor 5, p130-binding	0.020
KIF14	kinesin family member 14	0.020
C4orf43	chromosome 4 open reading frame 43	0.020
HDAC2	histone deacetylase 2	0.019
TFDP1	transcription factor Dp-1	0.019
SMC3	structural maintenance of chromosomes 3	0.019
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.018
STAG1	stromal antigen 1	0.018
DEPDC1	DEP domain containing 1	0.018
GAS2L3	growth arrest-specific 2 like 3	0.017
SMC1A	structural maintenance of chromosomes 1A	0.017
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.016
RAD21	RAD21 homolog (S. pombe)	0.016
MBD1	methyl-CpG binding domain protein 1	0.016
HJURP	Holliday junction recognition protein	0.016
SKA1	spindle and kinetochore associated complex subunit 1	0.016
NEIL3	nei endonuclease VIII-like 3 (E. coli)	0.016
RRP1B	ribosomal RNA processing 1 homolog B (S. cerevisiae)	0.016
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.016
AURKA	aurora kinase A	0.016
PAFAH1B2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	0.015
ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	0.015
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.015
CAND1	cullin-associated and neddylation-dissociated 1	0.015
KIF20B	kinesin family member 20B	0.015
RSL1D1	ribosomal L1 domain containing 1	0.014
MKI67	antigen identified by monoclonal antibody Ki-67	0.014
ANLN	anillin, actin binding protein	0.014
DSN1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.013
SMARCAD1	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	0.013
WRN	Werner syndrome, RecQ helicase-like	0.013
C1orf112	chromosome 1 open reading frame 112	0.013
NCAPG2	non-SMC condensin II complex, subunit G2	0.013
TOPBP1	topoisomerase (DNA) II binding protein 1	0.013
VCP	valosin containing protein	0.013	Yeast
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.013
CCND1	cyclin D1	0.013
AMFR	autocrine motility factor receptor	0.012
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.012
RBM12	RNA binding motif protein 12	0.012
CBX1	chromobox homolog 1	0.012
SPC25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.012
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.012
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.012
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.012
CKS2	CDC28 protein kinase regulatory subunit 2	0.011
APC	adenomatous polyposis coli	0.011
KIF4A	kinesin family member 4A	0.011
TOP1	topoisomerase (DNA) I	0.011
UBXN2A	UBX domain protein 2A	0.011
UBXN6	UBX domain protein 6	0.011
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.011
RBL2	retinoblastoma-like 2 (p130)	0.010	Human
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.010
NSL1	NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.010
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.010