IMP: Integrative Multi-species Prediction

Homo sapiens

8 genes annotated in human

regulation of multicellular organism growth

Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of multicellular organism growth"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of multicellular organism growth" (in gray)

Name	Description	Probability	Func Analog Organism
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.953
TRIM28	tripartite motif containing 28	0.530
SMAD3	SMAD family member 3	0.528	Worm
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.464
SMAD2	SMAD family member 2	0.344	Worm
SKIL	SKI-like oncogene	0.325
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.313
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.310
NCOR1	nuclear receptor corepressor 1	0.294	Mouse
EP300	E1A binding protein p300	0.272
IRS1	insulin receptor substrate 1	0.248	Fly
CREBBP	CREB binding protein	0.242
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.235
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.223
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.218
SP1	Sp1 transcription factor	0.208
IGF1R	insulin-like growth factor 1 receptor	0.208	Worm Fly
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.175
FKBP1A	FK506 binding protein 1A, 12kDa	0.164
SMAD4	SMAD family member 4	0.158	Worm
ZFX	zinc finger protein, X-linked	0.153
STK3	serine/threonine kinase 3	0.151
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.149
AR	androgen receptor	0.144
INSR	insulin receptor	0.140	Worm Fly
CREB1	cAMP responsive element binding protein 1	0.126	Mouse
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.124
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.113
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.093	Fly
HTT	huntingtin	0.092
MBNL1	muscleblind-like (Drosophila)	0.089
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.080
BAD	BCL2-associated agonist of cell death	0.076
NBN	nibrin	0.076
MTA1	metastasis associated 1	0.068
TH1L	TH1-like (Drosophila)	0.065
GH1	growth hormone 1	0.063
RPL37A	ribosomal protein L37a	0.063
TUFM	Tu translation elongation factor, mitochondrial	0.062
SIRT1	sirtuin 1	0.058
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.057	Fly
EEF1A1	eukaryotic translation elongation factor 1 alpha 1	0.056
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.055
ESR1	estrogen receptor 1	0.054
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.051
NCOA6	nuclear receptor coactivator 6	0.049
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.049
VEZF1	vascular endothelial zinc finger 1	0.048
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.047
STK4	serine/threonine kinase 4	0.047
TXN	thioredoxin	0.042
RPL41	ribosomal protein L41	0.042
H2AFX	H2A histone family, member X	0.039
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.039	Worm
ADNP	activity-dependent neuroprotector homeobox	0.038
RPL27	ribosomal protein L27	0.038
PRDX1	peroxiredoxin 1	0.037	Worm
PIAS1	protein inhibitor of activated STAT, 1	0.033	Worm
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.033
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.032
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.032
PABPC1	poly(A) binding protein, cytoplasmic 1	0.031
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.031	Mouse
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.029
RPL7	ribosomal protein L7	0.029
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.027
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.027
HSPB1	heat shock 27kDa protein 1	0.027
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.026	Worm
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.026
ERBB2IP	erbb2 interacting protein	0.026
RAD21	RAD21 homolog (S. pombe)	0.026
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.026
EGFR	epidermal growth factor receptor	0.025
TRIO	triple functional domain (PTPRF interacting)	0.025	Worm
ARID1A	AT rich interactive domain 1A (SWI-like)	0.024
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.024
SMAD5	SMAD family member 5	0.024	Worm
USP9X	ubiquitin specific peptidase 9, X-linked	0.023
GRB10	growth factor receptor-bound protein 10	0.023
RPLP0	ribosomal protein, large, P0	0.023
XIAP	X-linked inhibitor of apoptosis	0.023
CDT1	chromatin licensing and DNA replication factor 1	0.022
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.022
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.021	Human
WAPAL	wings apart-like homolog (Drosophila)	0.021
PAX3	paired box 3	0.021
RBBP4	retinoblastoma binding protein 4	0.021
NCOA1	nuclear receptor coactivator 1	0.021
EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	0.021
RPL27A	ribosomal protein L27a	0.020
IKBKAP	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	0.020
ADAM10	ADAM metallopeptidase domain 10	0.020
RPL34	ribosomal protein L34	0.020
CLASP1	cytoplasmic linker associated protein 1	0.019
CBX3	chromobox homolog 3	0.019	Worm
GHR	growth hormone receptor	0.019
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.018
ILF3	interleukin enhancer binding factor 3, 90kDa	0.018
ERO1L	ERO1-like (S. cerevisiae)	0.018
CBX5	chromobox homolog 5	0.018	Worm
CALCA	calcitonin-related polypeptide alpha	0.018
FAF1	Fas (TNFRSF6) associated factor 1	0.017
RXRA	retinoid X receptor, alpha	0.017
SUB1	SUB1 homolog (S. cerevisiae)	0.017
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	0.017
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.017
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.017
PIAS2	protein inhibitor of activated STAT, 2	0.017	Worm
ENO1	enolase 1, (alpha)	0.016	Worm
ICT1	immature colon carcinoma transcript 1	0.016
ZMYM2	zinc finger, MYM-type 2	0.016
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.016
STAG2	stromal antigen 2	0.016
MED27	mediator complex subunit 27	0.016
CHD8	chromodomain helicase DNA binding protein 8	0.016
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.016
TRIM33	tripartite motif containing 33	0.016
MAGEA2	melanoma antigen family A, 2	0.016
APC	adenomatous polyposis coli	0.016
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.015
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.015
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.015
ATF2	activating transcription factor 2	0.015
TDG	thymine-DNA glycosylase	0.015
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.015
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.015
ORC1	origin recognition complex, subunit 1	0.015	Zebrafish
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.015
BOP1	block of proliferation 1	0.015
MTDH	metadherin	0.014
SMAD7	SMAD family member 7	0.014
SNIP1	Smad nuclear interacting protein 1	0.014
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.014
EIF4B	eukaryotic translation initiation factor 4B	0.014
ATXN1	ataxin 1	0.014
PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.014
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.014
AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	0.014
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.013
NCOA2	nuclear receptor coactivator 2	0.013
RICTOR	RPTOR independent companion of MTOR, complex 2	0.013
ADORA2A	adenosine A2a receptor	0.013
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	0.013
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.013
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.013
TNRC6A	trinucleotide repeat containing 6A	0.013
FLNB	filamin B, beta	0.013
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.012
WAC	WW domain containing adaptor with coiled-coil	0.012
ZMYND11	zinc finger, MYND-type containing 11	0.012
BCL2L1	BCL2-like 1	0.012
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.012
PCM1	pericentriolar material 1	0.012
CUL3	cullin 3	0.012
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012	Fly
PUM2	pumilio homolog 2 (Drosophila)	0.012
ZNF148	zinc finger protein 148	0.012
CNPY2	canopy 2 homolog (zebrafish)	0.012
FGF10	fibroblast growth factor 10	0.012
EBNA1BP2	EBNA1 binding protein 2	0.012
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.012
EVL	Enah/Vasp-like	0.012
NUP93	nucleoporin 93kDa	0.012
ELP3	elongation protein 3 homolog (S. cerevisiae)	0.011
CNOT3	CCR4-NOT transcription complex, subunit 3	0.011
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.011	Worm
SOX10	SRY (sex determining region Y)-box 10	0.011
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.011
PEX14	peroxisomal biogenesis factor 14	0.011
TKT	transketolase	0.011
MRPL12	mitochondrial ribosomal protein L12	0.011
STAG1	stromal antigen 1	0.011
CRH	corticotropin releasing hormone	0.011
HDAC3	histone deacetylase 3	0.011	Mouse
PDIA4	protein disulfide isomerase family A, member 4	0.011	Worm
NAV1	neuron navigator 1	0.011	Worm
POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	0.011
PBRM1	polybromo 1	0.011
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.011
SMAD1	SMAD family member 1	0.010	Worm
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.010
MAP2K1	mitogen-activated protein kinase kinase 1	0.010
CNOT1	CCR4-NOT transcription complex, subunit 1	0.010
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.010
RPL24	ribosomal protein L24	0.010
MBD1	methyl-CpG binding domain protein 1	0.010
ACACA	acetyl-CoA carboxylase alpha	0.010
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.010