IMP: Integrative Multi-species Prediction

Homo sapiens

314 genes annotated in human

regulation of kinase activity

Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of kinase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
EGFR	epidermal growth factor receptor	1.000
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	1.000	Rat Fly
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	1.000	Human Rat Fly
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	1.000
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	1.000	Human Fly
GRB2	growth factor receptor-bound protein 2	1.000	Fly
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	1.000
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	1.000
RB1	retinoblastoma 1	1.000
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	1.000	Mouse Fly
FYN	FYN oncogene related to SRC, FGR, YES	1.000	Human Zebrafish Fly
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1.000
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.999
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.998
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.998
MAPK14	mitogen-activated protein kinase 14	0.998
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.998
JUN	jun proto-oncogene	0.998
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.996
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.996
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.996	Yeast Mouse
BCAR1	breast cancer anti-estrogen resistance 1	0.996
TRAF6	TNF receptor-associated factor 6	0.994
TP53	tumor protein p53	0.994	Fly
SH3KBP1	SH3-domain kinase binding protein 1	0.992
PLCG1	phospholipase C, gamma 1	0.991
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.991
MAPK8	mitogen-activated protein kinase 8	0.990	Fly
SNX9	sorting nexin 9	0.990
PRKCZ	protein kinase C, zeta	0.987	Human Rat
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.982
FGFR2	fibroblast growth factor receptor 2	0.976	Human Fly
UBC	ubiquitin C	0.976
FGFR1	fibroblast growth factor receptor 1	0.974
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.974	Fly
CCNE1	cyclin E1	0.973	Mouse Worm Fly
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.972	Rat
PTK2	PTK2 protein tyrosine kinase 2	0.971
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.969
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.969	Human Mouse
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.967
DUSP1	dual specificity phosphatase 1	0.961
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.960
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.957
GAB1	GRB2-associated binding protein 1	0.956	Mouse
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.953	Human Mouse
ARRB1	arrestin, beta 1	0.947
IGF1R	insulin-like growth factor 1 receptor	0.945
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.944
MAPK1	mitogen-activated protein kinase 1	0.942
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.937
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.936	Fly
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.931	Rat
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.928	Mouse
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.927
BBS10	Bardet-Biedl syndrome 10	0.924
CAV1	caveolin 1, caveolae protein, 22kDa	0.911	Mouse
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.908
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.905
MAP2K4	mitogen-activated protein kinase kinase 4	0.901	Human Zebrafish Rat Worm Fly
TNK2	tyrosine kinase, non-receptor, 2	0.891	Human
TSC2	tuberous sclerosis 2	0.884	Mouse Rat
ESR1	estrogen receptor 1	0.883
TRAF1	TNF receptor-associated factor 1	0.878	Human
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.875	Rat
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.875	Human
GRB7	growth factor receptor-bound protein 7	0.874
FGF1	fibroblast growth factor 1 (acidic)	0.874	Human
PDPK1	3-phosphoinositide dependent protein kinase-1	0.870
YAP1	Yes-associated protein 1	0.864	Human
LRRK2	leucine-rich repeat kinase 2	0.863
TOLLIP	toll interacting protein	0.863
GSK3B	glycogen synthase kinase 3 beta	0.861	Rat Fly
CDK2	cyclin-dependent kinase 2	0.854
ABI1	abl-interactor 1	0.853	Mouse Fly
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.850
IRAK2	interleukin-1 receptor-associated kinase 2	0.849	Human
BRCA1	breast cancer 1, early onset	0.844
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.843
SOCS1	suppressor of cytokine signaling 1	0.842	Human Mouse
CDK14	cyclin-dependent kinase 14	0.839
BIRC2	baculoviral IAP repeat containing 2	0.828
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.828
AXL	AXL receptor tyrosine kinase	0.825	Human
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.820
SOS1	son of sevenless homolog 1 (Drosophila)	0.820
ZNF43	zinc finger protein 43	0.817
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.817	Mouse
SMAD3	SMAD family member 3	0.813
ATF3	activating transcription factor 3	0.810	Fly
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.809
STK11	serine/threonine kinase 11	0.803
C1QA	complement component 1, q subcomponent, A chain	0.798	Human
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.796
CCND1	cyclin D1	0.794
GRB10	growth factor receptor-bound protein 10	0.790
ADAM15	ADAM metallopeptidase domain 15	0.781	Human
SMAD7	SMAD family member 7	0.774
MYD88	myeloid differentiation primary response gene (88)	0.768
CYR61	cysteine-rich, angiogenic inducer, 61	0.764
NCK1	NCK adaptor protein 1	0.764
AXIN1	axin 1	0.763
RICTOR	RPTOR independent companion of MTOR, complex 2	0.760
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.757
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.755	Human
CSNK1E	casein kinase 1, epsilon	0.753
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.752
MAP2K1	mitogen-activated protein kinase kinase 1	0.752
PTEN	phosphatase and tensin homolog	0.740
TRAF2	TNF receptor-associated factor 2	0.738
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.734
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.732
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.730
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.728
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.726
PINK1	PTEN induced putative kinase 1	0.717
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.716
CCND3	cyclin D3	0.708
IRS1	insulin receptor substrate 1	0.701	Mouse Rat
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.700
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.698
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.695	Human Rat
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.689	Human
MUC1	mucin 1, cell surface associated	0.689
BMPR1A	bone morphogenetic protein receptor, type IA	0.682	Human
ZNF253	zinc finger protein 253	0.676
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.671
SMAD2	SMAD family member 2	0.670
JUNB	jun B proto-oncogene	0.669
IER2	immediate early response 2	0.668
CDK6	cyclin-dependent kinase 6	0.667
XIAP	X-linked inhibitor of apoptosis	0.667
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.665
NRP1	neuropilin 1	0.664
SPRY4	sprouty homolog 4 (Drosophila)	0.664	Human Mouse
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.663
IQGAP1	IQ motif containing GTPase activating protein 1	0.663
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.662
PRNP	prion protein	0.659
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.658
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.651
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.646
GHR	growth hormone receptor	0.641	Human Rat
VAV1	vav 1 guanine nucleotide exchange factor	0.638
RNF11	ring finger protein 11	0.637
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.626
CDK9	cyclin-dependent kinase 9	0.624
SQSTM1	sequestosome 1	0.620
DLG1	discs, large homolog 1 (Drosophila)	0.619	Mouse
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.618
ILK	integrin-linked kinase	0.610	Rat
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.609
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.608
PRKCI	protein kinase C, iota	0.608	Human
IL1R1	interleukin 1 receptor, type I	0.606
CDK4	cyclin-dependent kinase 4	0.596
SKP2	S-phase kinase-associated protein 2 (p45)	0.589
CCR5	chemokine (C-C motif) receptor 5	0.582
MAPT	microtubule-associated protein tau	0.580
FAS	Fas (TNF receptor superfamily, member 6)	0.574
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.571
SPRY2	sprouty homolog 2 (Drosophila)	0.562
SORBS3	sorbin and SH3 domain containing 3	0.561
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.561
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.559	Human
APP	amyloid beta (A4) precursor protein	0.556	Mouse
KLF6	Kruppel-like factor 6	0.554
MED28	mediator complex subunit 28	0.553
ZNF746	zinc finger protein 746	0.546
BIRC3	baculoviral IAP repeat containing 3	0.545
ADRB2	adrenergic, beta-2-, receptor, surface	0.542	Human
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.542	Mouse
CREBBP	CREB binding protein	0.541
TRAF5	TNF receptor-associated factor 5	0.541	Human
EGR1	early growth response 1	0.536	Worm
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.536	Worm
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.532	Fly
SFN	stratifin	0.519	Mouse
JUND	jun D proto-oncogene	0.512
PRDX4	peroxiredoxin 4	0.511	Human
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.510
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.501	Worm
TP73	tumor protein p73	0.499	Mouse Rat
STAT5A	signal transducer and activator of transcription 5A	0.483
IER3	immediate early response 3	0.482
NCOA3	nuclear receptor coactivator 3	0.480
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.478
BTRC	beta-transducin repeat containing	0.469
JAK2	Janus kinase 2	0.466	Mouse Rat
PTPRB	protein tyrosine phosphatase, receptor type, B	0.462	Human
DUSP5	dual specificity phosphatase 5	0.459	Human Rat
ZNF273	zinc finger protein 273	0.457	Human
CCL4	chemokine (C-C motif) ligand 4	0.455	Human
MAPK10	mitogen-activated protein kinase 10	0.454	Fly
RARA	retinoic acid receptor, alpha	0.452	Rat
PIAS4	protein inhibitor of activated STAT, 4	0.450
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.449	Human
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.448
CHUK	conserved helix-loop-helix ubiquitous kinase	0.447
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.447
NBN	nibrin	0.445
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.444
ABI2	abl-interactor 2	0.444	Fly
BTK	Bruton agammaglobulinemia tyrosine kinase	0.441	Human
SKP1	S-phase kinase-associated protein 1	0.436
CCNA2	cyclin A2	0.433	Fly
ENG	endoglin	0.431
SOCS3	suppressor of cytokine signaling 3	0.430	Human
ATF2	activating transcription factor 2	0.423
CSK	c-src tyrosine kinase	0.419	Rat
CCNB2	cyclin B2	0.416	Yeast Worm Fly
GAS7	growth arrest-specific 7	0.415
IDI1	isopentenyl-diphosphate delta isomerase 1	0.415
CD14	CD14 molecule	0.413
SPRR2A	small proline-rich protein 2A	0.410
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.407
BMP2	bone morphogenetic protein 2	0.406
EPOR	erythropoietin receptor	0.404
LAMP1	lysosomal-associated membrane protein 1	0.404
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.403
FKBP1A	FK506 binding protein 1A, 12kDa	0.402
HCK	hemopoietic cell kinase	0.401	Human Fly
ELP2	elongation protein 2 homolog (S. cerevisiae)	0.399
TXN	thioredoxin	0.398
ADAM19	ADAM metallopeptidase domain 19	0.398	Human
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.393
TNF	tumor necrosis factor	0.392
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.390
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.388
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.388	Human
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.387	Human
EGR3	early growth response 3	0.386	Worm
RIN1	Ras and Rab interactor 1	0.385
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.384
TEK	TEK tyrosine kinase, endothelial	0.383
PSG9	pregnancy specific beta-1-glycoprotein 9	0.383	Rat
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.382
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.382	Human
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.381
E2F1	E2F transcription factor 1	0.379
SETDB1	SET domain, bifurcated 1	0.379
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.376
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.374
SC4MOL	sterol-C4-methyl oxidase-like	0.374
VAV3	vav 3 guanine nucleotide exchange factor	0.374	Mouse
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.373
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.373	Mouse Rat Fly
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.372	Human Zebrafish Fly
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.371
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.370
SMN1	survival of motor neuron 1, telomeric	0.369
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.369
ANKRD28	ankyrin repeat domain 28	0.368
NCOA1	nuclear receptor coactivator 1	0.362
MAPK3	mitogen-activated protein kinase 3	0.361
BRCA2	breast cancer 2, early onset	0.360
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.360	Mouse Rat
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.360
DOCK7	dedicator of cytokinesis 7	0.358
RIPK2	receptor-interacting serine-threonine kinase 2	0.357	Human
EP300	E1A binding protein p300	0.357
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.357
ZNF675	zinc finger protein 675	0.356
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.354
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.354
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.353
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.347
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.347
DUSP23	dual specificity phosphatase 23	0.346
SRCIN1	SRC kinase signaling inhibitor 1	0.345
DCN	decorin	0.345
AKAP2	A kinase (PRKA) anchor protein 2	0.345
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.345
TGFB2	transforming growth factor, beta 2	0.343
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.340
ARHGAP1	Rho GTPase activating protein 1	0.339
DUSP6	dual specificity phosphatase 6	0.339
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.333	Mouse Fly
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.331
TFF1	trefoil factor 1	0.329
FAF1	Fas (TNFRSF6) associated factor 1	0.328
EGR2	early growth response 2	0.326
DLG4	discs, large homolog 4 (Drosophila)	0.326
LAT	linker for activation of T cells	0.325
WT1	Wilms tumor 1	0.325
CCND2	cyclin D2	0.324
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.323
GAB2	GRB2-associated binding protein 2	0.322
IL1B	interleukin 1, beta	0.322
BCL10	B-cell CLL/lymphoma 10	0.321
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.319
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.318
SCHIP1	schwannomin interacting protein 1	0.316
SOCS5	suppressor of cytokine signaling 5	0.313
SIRT1	sirtuin 1	0.312
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.312
KIF23	kinesin family member 23	0.310
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.310
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.308
TGFBR1	transforming growth factor, beta receptor 1	0.305
IRAK1	interleukin-1 receptor-associated kinase 1	0.303
FGF7	fibroblast growth factor 7	0.303	Human
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.302
HIPK2	homeodomain interacting protein kinase 2	0.301
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.301
NRG1	neuregulin 1	0.300
NLRC4	NLR family, CARD domain containing 4	0.299
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.299
NCAM1	neural cell adhesion molecule 1	0.297
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.295
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.295
C1QC	complement component 1, q subcomponent, C chain	0.294	Human
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.293
CD40	CD40 molecule, TNF receptor superfamily member 5	0.293
TNS4	tensin 4	0.292
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.292
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.292
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.290
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.290
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.290
MAP2K7	mitogen-activated protein kinase kinase 7	0.289
LRP6	low density lipoprotein receptor-related protein 6	0.289
RPS14	ribosomal protein S14	0.288
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.288
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.287
CCL19	chemokine (C-C motif) ligand 19	0.286
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.285	Human
DUSP7	dual specificity phosphatase 7	0.284
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.282	Human
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.282
BLNK	B-cell linker	0.282
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.281
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.280
RAB21	RAB21, member RAS oncogene family	0.279
LDLR	low density lipoprotein receptor	0.275
BAD	BCL2-associated agonist of cell death	0.274
TRAF3	TNF receptor-associated factor 3	0.273	Human
GADD45B	growth arrest and DNA-damage-inducible, beta	0.273
INSR	insulin receptor	0.273
WEE1	WEE1 homolog (S. pombe)	0.271	Fly
PML	promyelocytic leukemia	0.271
RAD50	RAD50 homolog (S. cerevisiae)	0.270
CKS2	CDC28 protein kinase regulatory subunit 2	0.269
DNM1	dynamin 1	0.269
CCL2	chemokine (C-C motif) ligand 2	0.268	Human
ZMYND11	zinc finger, MYND-type containing 11	0.268
PPP6C	protein phosphatase 6, catalytic subunit	0.267
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.267
STRN3	striatin, calmodulin binding protein 3	0.267
GMFB	glia maturation factor, beta	0.266
FSTL1	follistatin-like 1	0.266
SOD1	superoxide dismutase 1, soluble	0.266
ACHE	acetylcholinesterase	0.265
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.264
FBXW11	F-box and WD repeat domain containing 11	0.264
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.260
RHOA	ras homolog gene family, member A	0.259	Fly
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.257
ADAM17	ADAM metallopeptidase domain 17	0.257
A2M	alpha-2-macroglobulin	0.256
RPL23	ribosomal protein L23	0.255
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.253
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.250	Rat
WNT1	wingless-type MMTV integration site family, member 1	0.249	Human
ACVR1B	activin A receptor, type IB	0.249	Human
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.249	Human
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.247
PDGFC	platelet derived growth factor C	0.246	Mouse
FANCD2	Fanconi anemia, complementation group D2	0.246
CLTC	clathrin, heavy chain (Hc)	0.245
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.244	Rat
CDK1	cyclin-dependent kinase 1	0.243	Worm
SORBS1	sorbin and SH3 domain containing 1	0.243
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.242
ERRFI1	ERBB receptor feedback inhibitor 1	0.241
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.241
RET	ret proto-oncogene	0.240
PTK6	PTK6 protein tyrosine kinase 6	0.239
SH3RF1	SH3 domain containing ring finger 1	0.239
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.238
TGFB3	transforming growth factor, beta 3	0.238	Rat
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.238
WASL	Wiskott-Aldrich syndrome-like	0.235
AMOTL2	angiomotin like 2	0.234
JAG1	jagged 1	0.234
OXSR1	oxidative-stress responsive 1	0.234
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.233
CUL2	cullin 2	0.233
SPTBN1	spectrin, beta, non-erythrocytic 1	0.232
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.231	Fly
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.231
TSC22D1	TSC22 domain family, member 1	0.230
IL6	interleukin 6 (interferon, beta 2)	0.230
SFRP1	secreted frizzled-related protein 1	0.230	Mouse
TM4SF1	transmembrane 4 L six family member 1	0.229
CD28	CD28 molecule	0.228
PRDX1	peroxiredoxin 1	0.228	Human
IGFBP3	insulin-like growth factor binding protein 3	0.228
DDIT3	DNA-damage-inducible transcript 3	0.227
BCR	breakpoint cluster region	0.226
MAPK9	mitogen-activated protein kinase 9	0.225	Fly
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.223	Mouse
SPRED1	sprouty-related, EVH1 domain containing 1	0.223	Mouse
CCL8	chemokine (C-C motif) ligand 8	0.223	Human
ITK	IL2-inducible T-cell kinase	0.223
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.223
ZNF91	zinc finger protein 91	0.222
PDCD6IP	programmed cell death 6 interacting protein	0.222
ZNF708	zinc finger protein 708	0.222	Human
MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	0.221
CACYBP	calcyclin binding protein	0.221
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.220
CEP170	centrosomal protein 170kDa	0.220
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.219
TLR2	toll-like receptor 2	0.218
HBEGF	heparin-binding EGF-like growth factor	0.217
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.216	Fly
RPL10	ribosomal protein L10	0.216
LIMK1	LIM domain kinase 1	0.215
SEPT7	septin 7	0.215
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.213	Human
CUL1	cullin 1	0.212
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.212
TGFA	transforming growth factor, alpha	0.212
WNT3A	wingless-type MMTV integration site family, member 3A	0.211	Human Mouse
MPDZ	multiple PDZ domain protein	0.210
RBBP8	retinoblastoma binding protein 8	0.208
NUMBL	numb homolog (Drosophila)-like	0.206
CAPG	capping protein (actin filament), gelsolin-like	0.206
THBS2	thrombospondin 2	0.206	Human
CALCA	calcitonin-related polypeptide alpha	0.206
SYK	spleen tyrosine kinase	0.205	Mouse
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.205	Human
FZD1	frizzled homolog 1 (Drosophila)	0.204	Human
IK	IK cytokine, down-regulator of HLA II	0.204
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.204
FGF4	fibroblast growth factor 4	0.204	Human
RFWD2	ring finger and WD repeat domain 2	0.204
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.203
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.202	Human
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.201	Human
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.201
JAK3	Janus kinase 3	0.201
SMAD1	SMAD family member 1	0.199
FOXM1	forkhead box M1	0.199
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.199
PRKCG	protein kinase C, gamma	0.199	Human
TTR	transthyretin	0.198
FEM1B	fem-1 homolog b (C. elegans)	0.198
NCOR2	nuclear receptor corepressor 2	0.198
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.197
BMI1	BMI1 polycomb ring finger oncogene	0.197
PGR	progesterone receptor	0.195
FZD7	frizzled homolog 7 (Drosophila)	0.195	Human
ACVR1	activin A receptor, type I	0.194	Human
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.194	Mouse Rat
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.194
GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1	0.193
AMOTL1	angiomotin like 1	0.193
FBXL12	F-box and leucine-rich repeat protein 12	0.193
SNIP1	Smad nuclear interacting protein 1	0.192
TGFB1	transforming growth factor, beta 1	0.192
ATF5	activating transcription factor 5	0.190
TANK	TRAF family member-associated NFKB activator	0.190
BAG3	BCL2-associated athanogene 3	0.190
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.188
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.187
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.187
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.187
ELP4	elongation protein 4 homolog (S. cerevisiae)	0.187
TRADD	TNFRSF1A-associated via death domain	0.187
TNS3	tensin 3	0.186
LARP7	La ribonucleoprotein domain family, member 7	0.186
ELK1	ELK1, member of ETS oncogene family	0.185
CXCR4	chemokine (C-X-C motif) receptor 4	0.185
EFNA5	ephrin-A5	0.184
TICAM2	toll-like receptor adaptor molecule 2	0.184
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.184
DPYSL4	dihydropyrimidinase-like 4	0.184
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.184
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.183
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.183
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.183
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.183
HDAC1	histone deacetylase 1	0.182
ZNF430	zinc finger protein 430	0.182	Human
MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3	0.182
CCL14	chemokine (C-C motif) ligand 14	0.182	Human
MTA1	metastasis associated 1	0.181
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.181
PDGFA	platelet-derived growth factor alpha polypeptide	0.181
WIPF1	WAS/WASL interacting protein family, member 1	0.180
CCNE2	cyclin E2	0.180	Mouse Worm Fly
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.179
DOCK1	dedicator of cytokinesis 1	0.177
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.177
CBX1	chromobox homolog 1	0.177
EPHA2	EPH receptor A2	0.177	Human
CFLAR	CASP8 and FADD-like apoptosis regulator	0.177
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.176
HP	haptoglobin	0.176
PROX1	prospero homeobox 1	0.176
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.176
VEGFA	vascular endothelial growth factor A	0.175
IRF4	interferon regulatory factor 4	0.174
ZNF254	zinc finger protein 254	0.174	Human
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.174
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.173	Rat
TLR4	toll-like receptor 4	0.173	Human Mouse
ZNF85	zinc finger protein 85	0.173	Human
PSG5	pregnancy specific beta-1-glycoprotein 5	0.173	Rat
RGS1	regulator of G-protein signaling 1	0.172
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.172
SP110	SP110 nuclear body protein	0.171
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.171
CTGF	connective tissue growth factor	0.171	Human
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.171
CSH2	chorionic somatomammotropin hormone 2	0.170	Human
MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)	0.170
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.170	Human
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.169
ARF6	ADP-ribosylation factor 6	0.169
YY1	YY1 transcription factor	0.169
COL2A1	collagen, type II, alpha 1	0.169
FLNA	filamin A, alpha	0.169
PDE4DIP	phosphodiesterase 4D interacting protein	0.169
VAV2	vav 2 guanine nucleotide exchange factor	0.168	Mouse
MYOD1	myogenic differentiation 1	0.167
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.167
FGF18	fibroblast growth factor 18	0.167
FGA	fibrinogen alpha chain	0.167
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.167
COL14A1	collagen, type XIV, alpha 1	0.167
SH3GL3	SH3-domain GRB2-like 3	0.166
CXCL12	chemokine (C-X-C motif) ligand 12	0.166
PRKCD	protein kinase C, delta	0.166
BMP4	bone morphogenetic protein 4	0.166
TP53BP2	tumor protein p53 binding protein, 2	0.166	Fly
PICK1	protein interacting with PRKCA 1	0.165
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.165
SORT1	sortilin 1	0.165
GAS6	growth arrest-specific 6	0.164
SIAH1	seven in absentia homolog 1 (Drosophila)	0.163
EPHB2	EPH receptor B2	0.163	Human
TSPAN4	tetraspanin 4	0.162
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.162
ATP4B	ATPase, H+/K+ exchanging, beta polypeptide	0.162
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.162	Human
GH2	growth hormone 2	0.162	Human
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.162
RAP1A	RAP1A, member of RAS oncogene family	0.162	Rat
CYTIP	cytohesin 1 interacting protein	0.161
ELP3	elongation protein 3 homolog (S. cerevisiae)	0.160
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.160
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.160	Mouse
ARRB2	arrestin, beta 2	0.160
IGF1	insulin-like growth factor 1 (somatomedin C)	0.159	Human
FOSL1	FOS-like antigen 1	0.159	Fly
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.159
TSC1	tuberous sclerosis 1	0.159	Mouse
TBXA2R	thromboxane A2 receptor	0.159
GH1	growth hormone 1	0.159
DARC	Duffy blood group, chemokine receptor	0.158
KDM6B	lysine (K)-specific demethylase 6B	0.158
EIF4E	eukaryotic translation initiation factor 4E	0.158
APLP1	amyloid beta (A4) precursor-like protein 1	0.158
FGF2	fibroblast growth factor 2 (basic)	0.157
ZNF680	zinc finger protein 680	0.157	Human
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.157
ZNF496	zinc finger protein 496	0.157
PLEK	pleckstrin	0.156
CDH5	cadherin 5, type 2 (vascular endothelium)	0.155
CCL11	chemokine (C-C motif) ligand 11	0.155	Human
BDNF	brain-derived neurotrophic factor	0.154	Human
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.154
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.154
CSRNP1	cysteine-serine-rich nuclear protein 1	0.154
CCNA1	cyclin A1	0.154	Fly
CREB1	cAMP responsive element binding protein 1	0.154
ZNF93	zinc finger protein 93	0.153
CCR1	chemokine (C-C motif) receptor 1	0.153
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.153	Human
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.153
RHOB	ras homolog gene family, member B	0.153
LMO2	LIM domain only 2 (rhombotin-like 1)	0.153
LIMD1	LIM domains containing 1	0.153
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.152
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.152
FGF8	fibroblast growth factor 8 (androgen-induced)	0.151
RHOU	ras homolog gene family, member U	0.150
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.150
SNAI1	snail homolog 1 (Drosophila)	0.150
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.150
GFER	growth factor, augmenter of liver regeneration	0.149
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.149
SH2D3A	SH2 domain containing 3A	0.149
PVRL3	poliovirus receptor-related 3	0.149
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.147
HNF4A	hepatocyte nuclear factor 4, alpha	0.147	Human Rat
RAB1A	RAB1A, member RAS oncogene family	0.147
TLN1	talin 1	0.147
AKAP1	A kinase (PRKA) anchor protein 1	0.147
DDR2	discoidin domain receptor tyrosine kinase 2	0.147
TRIB1	tribbles homolog 1 (Drosophila)	0.146
SH3GL2	SH3-domain GRB2-like 2	0.146
GDF9	growth differentiation factor 9	0.146
PRDM8	PR domain containing 8	0.145
BCL2	B-cell CLL/lymphoma 2	0.145
CCL13	chemokine (C-C motif) ligand 13	0.145	Human
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.145
PSG6	pregnancy specific beta-1-glycoprotein 6	0.144	Rat
NCK2	NCK adaptor protein 2	0.144	Human
BCL3	B-cell CLL/lymphoma 3	0.143
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.143
C1QB	complement component 1, q subcomponent, B chain	0.142	Human
PEBP1	phosphatidylethanolamine binding protein 1	0.142
GBP3	guanylate binding protein 3	0.142
RALBP1	ralA binding protein 1	0.142
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.142
ACTL6B	actin-like 6B	0.142
PRKCB	protein kinase C, beta	0.142
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.141
NCF2	neutrophil cytosolic factor 2	0.141
KIF5B	kinesin family member 5B	0.141
MED21	mediator complex subunit 21	0.140
PRKCE	protein kinase C, epsilon	0.140
PSG4	pregnancy specific beta-1-glycoprotein 4	0.140
ZNF107	zinc finger protein 107	0.139
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.139	Rat
CXCL9	chemokine (C-X-C motif) ligand 9	0.138
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.138
CCNB1	cyclin B1	0.138	Yeast Worm Fly
UBASH3B	ubiquitin associated and SH3 domain containing B	0.137	Mouse
EZR	ezrin	0.137
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.137
CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	0.137
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.137	Mouse
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.137
PLEC	plectin	0.136
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.136	Human
SNX33	sorting nexin 33	0.136	Human
PBK	PDZ binding kinase	0.136
MAP2K3	mitogen-activated protein kinase kinase 3	0.135
PLK1	polo-like kinase 1	0.134
ZNF282	zinc finger protein 282	0.134
RUNX1	runt-related transcription factor 1	0.134
FGFR3	fibroblast growth factor receptor 3	0.133
DUSP4	dual specificity phosphatase 4	0.133	Human Rat
CDK17	cyclin-dependent kinase 17	0.133
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.133
MAP3K10	mitogen-activated protein kinase kinase kinase 10	0.132
PTPRR	protein tyrosine phosphatase, receptor type, R	0.132
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.132
TBC1D17	TBC1 domain family, member 17	0.132
ANXA7	annexin A7	0.132
TG	thyroglobulin	0.131
PGF	placental growth factor	0.131	Human
NLK	nemo-like kinase	0.130
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.130
CCNH	cyclin H	0.130	Yeast
IL1RAP	interleukin 1 receptor accessory protein	0.129
S100B	S100 calcium binding protein B	0.129
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.129
LTK	leukocyte receptor tyrosine kinase	0.129	Human Fly
IL1A	interleukin 1, alpha	0.128	Human
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.128
FLT4	fms-related tyrosine kinase 4	0.128	Human
MAGED2	melanoma antigen family D, 2	0.128
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.128
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.128
MKL1	megakaryoblastic leukemia (translocation) 1	0.128	Human
CD2	CD2 molecule	0.128
STRADA	STE20-related kinase adaptor alpha	0.128
ZNF263	zinc finger protein 263	0.127
HDAC6	histone deacetylase 6	0.127
CRY1	cryptochrome 1 (photolyase-like)	0.127
NPY2R	neuropeptide Y receptor Y2	0.127
MYO1C	myosin IC	0.127
LIMS1	LIM and senescent cell antigen-like domains 1	0.126
CCL22	chemokine (C-C motif) ligand 22	0.126	Human
RND3	Rho family GTPase 3	0.126
MED25	mediator complex subunit 25	0.126
DAB1	disabled homolog 1 (Drosophila)	0.125	Mouse
AKT1S1	AKT1 substrate 1 (proline-rich)	0.125
ZNF117	zinc finger protein 117	0.125	Human
MAPK6	mitogen-activated protein kinase 6	0.125
DOK4	docking protein 4	0.125
TOP1	topoisomerase (DNA) I	0.125
SOS2	son of sevenless homolog 2 (Drosophila)	0.124
CRMP1	collapsin response mediator protein 1	0.124
LTBP4	latent transforming growth factor beta binding protein 4	0.124
MDC1	mediator of DNA-damage checkpoint 1	0.124
DLG5	discs, large homolog 5 (Drosophila)	0.123
RTKN	rhotekin	0.123
MARK2	MAP/microtubule affinity-regulating kinase 2	0.123
AXIN2	axin 2	0.123	Human Rat
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.123
RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	0.123
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.122
E2F5	E2F transcription factor 5, p130-binding	0.122
CDCP1	CUB domain containing protein 1	0.122
XAB2	XPA binding protein 2	0.122
EFNB2	ephrin-B2	0.122
RARG	retinoic acid receptor, gamma	0.122
DAPK1	death-associated protein kinase 1	0.121
EPHA3	EPH receptor A3	0.121	Human
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.120
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.120
GPSM2	G-protein signaling modulator 2	0.120
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.120	Mouse
COL6A1	collagen, type VI, alpha 1	0.120
INHBA	inhibin, beta A	0.120
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.119
ZNF71	zinc finger protein 71	0.119
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.119
FIBP	fibroblast growth factor (acidic) intracellular binding protein	0.118
RGS16	regulator of G-protein signaling 16	0.118
ZBTB48	zinc finger and BTB domain containing 48	0.117
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.117
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.117
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.117
CAMKV	CaM kinase-like vesicle-associated	0.117	Human
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.117
NOTCH1	notch 1	0.117
IDE	insulin-degrading enzyme	0.116
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.116	Human
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.116
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.116
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.115
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.115
NOV	nephroblastoma overexpressed gene	0.115	Human
PRKCA	protein kinase C, alpha	0.115	Mouse
NRP2	neuropilin 2	0.115
AMOT	angiomotin	0.115
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.115
IGF2R	insulin-like growth factor 2 receptor	0.114
SRI	sorcin	0.114
IRS2	insulin receptor substrate 2	0.114	Mouse
GDNF	glial cell derived neurotrophic factor	0.114
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.114
APOC1	apolipoprotein C-I	0.114
CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.114	Human
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.114
HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	0.113
IRAK3	interleukin-1 receptor-associated kinase 3	0.113
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.113	Mouse
GCK	glucokinase (hexokinase 4)	0.113
NCF1	neutrophil cytosolic factor 1	0.113
FGF10	fibroblast growth factor 10	0.113
FGF5	fibroblast growth factor 5	0.113	Human