IMP: Integrative Multi-species Prediction

Homo sapiens

15 genes annotated in human

Multi-species View

histone demethylation

GO:0016577

The modification of histones by removal of methyl groups.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone demethylation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "histone demethylation" (in gray)

Name	Description	Probability	Func Analog Organism
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.744
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.566
BCOR	BCL6 corepressor	0.554
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.406
ZFX	zinc finger protein, X-linked	0.392
ZCCHC17	zinc finger, CCHC domain containing 17	0.318
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.269
ESR1	estrogen receptor 1	0.253
ZNF512B	zinc finger protein 512B	0.226
KDM5B	lysine (K)-specific demethylase 5B	0.208
HBP1	HMG-box transcription factor 1	0.178
USP9Y	ubiquitin specific peptidase 9, Y-linked	0.153
BRD4	bromodomain containing 4	0.131
CCNL1	cyclin L1	0.113
RCOR1	REST corepressor 1	0.112
ZNF148	zinc finger protein 148	0.108
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.108
MKRN1	makorin ring finger protein 1	0.104
KLHL24	kelch-like 24 (Drosophila)	0.100
CEP350	centrosomal protein 350kDa	0.097
CYorf15A	chromosome Y open reading frame 15A	0.096
ZNF217	zinc finger protein 217	0.089
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.087
RLF	rearranged L-myc fusion	0.085
UBR2	ubiquitin protein ligase E3 component n-recognin 2	0.078
HELZ	helicase with zinc finger	0.075
NCOA6	nuclear receptor coactivator 6	0.067
ZNF292	zinc finger protein 292	0.066
UBXN7	UBX domain protein 7	0.058
RXRA	retinoid X receptor, alpha	0.057
GPBP1L1	GC-rich promoter binding protein 1-like 1	0.056
MTA3	metastasis associated 1 family, member 3	0.055
HIST1H3B	histone cluster 1, H3b	0.051
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.050
ANKRD12	ankyrin repeat domain 12	0.050
ZFY	zinc finger protein, Y-linked	0.044
RPS4Y1	ribosomal protein S4, Y-linked 1	0.041
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.041
CHD8	chromodomain helicase DNA binding protein 8	0.040
AR	androgen receptor	0.038
MTA1	metastasis associated 1	0.037
SUV39H2	suppressor of variegation 3-9 homolog 2 (Drosophila)	0.036
HIST1H4F	histone cluster 1, H4f	0.036
CCNG2	cyclin G2	0.035
PUM1	pumilio homolog 1 (Drosophila)	0.035
RICTOR	RPTOR independent companion of MTOR, complex 2	0.035
CUX1	cut-like homeobox 1	0.034
KIAA1267	KIAA1267	0.033
RCOR3	REST corepressor 3	0.032
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.032
BRD1	bromodomain containing 1	0.031
PRMT6	protein arginine methyltransferase 6	0.031
NCOR1	nuclear receptor corepressor 1	0.030
SETD2	SET domain containing 2	0.030
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.030
CHD4	chromodomain helicase DNA binding protein 4	0.030
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.028
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.027
CLK4	CDC-like kinase 4	0.027
WDR48	WD repeat domain 48	0.027
PCGF1	polycomb group ring finger 1	0.027
PHF21A	PHD finger protein 21A	0.026
MTA2	metastasis associated 1 family, member 2	0.025
USP9X	ubiquitin specific peptidase 9, X-linked	0.024
UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked	0.024	Mouse
JUND	jun D proto-oncogene	0.023
RIOK3	RIO kinase 3 (yeast)	0.023
MED13L	mediator complex subunit 13-like	0.023
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.023
SMAD7	SMAD family member 7	0.021
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.021
ATAD2B	ATPase family, AAA domain containing 2B	0.021
SAMD3	sterile alpha motif domain containing 3	0.020
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.020
ULK1	unc-51-like kinase 1 (C. elegans)	0.020
KIAA0182	KIAA0182	0.020
NCOA2	nuclear receptor coactivator 2	0.018
KDM5D	lysine (K)-specific demethylase 5D	0.018
KDM3A	lysine (K)-specific demethylase 3A	0.018
JARID2	jumonji, AT rich interactive domain 2	0.018
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.018
KIAA0240	KIAA0240	0.018
MAML1	mastermind-like 1 (Drosophila)	0.017
WDR26	WD repeat domain 26	0.017
MXI1	MAX interactor 1	0.016
NCOR2	nuclear receptor corepressor 2	0.015
PELP1	proline, glutamate and leucine rich protein 1	0.015
KDM6B	lysine (K)-specific demethylase 6B	0.014
PHF1	PHD finger protein 1	0.014
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.014
SNAI1	snail homolog 1 (Drosophila)	0.014
FAM9A	family with sequence similarity 9, member A	0.014
KDM2A	lysine (K)-specific demethylase 2A	0.014
PPARD	peroxisome proliferator-activated receptor delta	0.013
CSRNP1	cysteine-serine-rich nuclear protein 1	0.013
RBBP5	retinoblastoma binding protein 5	0.013
BRD2	bromodomain containing 2	0.013
GOLGB1	golgin B1	0.012
BAZ2A	bromodomain adjacent to zinc finger domain, 2A	0.012
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.011
BCL6	B-cell CLL/lymphoma 6	0.011
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.011
C20orf111	chromosome 20 open reading frame 111	0.011
H3F3C	H3 histone, family 3C	0.011
LOXL4	lysyl oxidase-like 4	0.011
RSBN1	round spermatid basic protein 1	0.011
ANKZF1	ankyrin repeat and zinc finger domain containing 1	0.010
IER2	immediate early response 2	0.010
STX19	syntaxin 19	0.010
ZNF395	zinc finger protein 395	0.010
KIAA0430	KIAA0430	0.010
ARL15	ADP-ribosylation factor-like 15	0.010