IMP: Integrative Multi-species Prediction

Homo sapiens

16 genes annotated in human

Multi-species View

histone phosphorylation

GO:0016572

The modification of histones by addition of phosphate groups.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone phosphorylation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "histone phosphorylation" (in gray)

Name	Description	Probability	Func Analog Organism
MAPK1	mitogen-activated protein kinase 1	0.949	Human
MAPK14	mitogen-activated protein kinase 14	0.944
PRKCA	protein kinase C, alpha	0.829
INCENP	inner centromere protein antigens 135/155kDa	0.633
NCF1	neutrophil cytosolic factor 1	0.583
DDB1	damage-specific DNA binding protein 1, 127kDa	0.404
CDK2	cyclin-dependent kinase 2	0.331
BIRC5	baculoviral IAP repeat containing 5	0.288
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.283
ARHGAP10	Rho GTPase activating protein 10	0.230
WRN	Werner syndrome, RecQ helicase-like	0.165
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.161
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.155
MAPK3	mitogen-activated protein kinase 3	0.144
RB1	retinoblastoma 1	0.142
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.136
GSK3B	glycogen synthase kinase 3 beta	0.107
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.107
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.090
CREBBP	CREB binding protein	0.080
USP5	ubiquitin specific peptidase 5 (isopeptidase T)	0.079
PLK1	polo-like kinase 1	0.077
CDK1	cyclin-dependent kinase 1	0.075	Human Rat
HTT	huntingtin	0.070
ITSN1	intersectin 1 (SH3 domain protein)	0.068
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.062
MAP2K1	mitogen-activated protein kinase kinase 1	0.052
AURKB	aurora kinase B	0.051	Mouse Fly
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.047
SETD8	SET domain containing (lysine methyltransferase) 8	0.043
RICTOR	RPTOR independent companion of MTOR, complex 2	0.042
COASY	CoA synthase	0.041
RAD18	RAD18 homolog (S. cerevisiae)	0.039
NBN	nibrin	0.039
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.039
DUSP3	dual specificity phosphatase 3	0.039
H2AFX	H2A histone family, member X	0.038
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.038	Human
CCNA2	cyclin A2	0.037
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.036
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.036
DUSP1	dual specificity phosphatase 1	0.035
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.034
AURKA	aurora kinase A	0.034	Mouse
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.034
RBBP8	retinoblastoma binding protein 8	0.034
EGFR	epidermal growth factor receptor	0.031
XPO1	exportin 1 (CRM1 homolog, yeast)	0.029
CCNE1	cyclin E1	0.029
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.028
PRKCD	protein kinase C, delta	0.028
RCC1	regulator of chromosome condensation 1	0.025
SPG7	spastic paraplegia 7 (pure and complicated autosomal recessive)	0.025
UBR2	ubiquitin protein ligase E3 component n-recognin 2	0.024
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.024
MAPT	microtubule-associated protein tau	0.024
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.023
EP300	E1A binding protein p300	0.023
NCL	nucleolin	0.022
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.022
CCDC101	coiled-coil domain containing 101	0.022
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.022
ARHGAP26	Rho GTPase activating protein 26	0.021
CDT1	chromatin licensing and DNA replication factor 1	0.021
GATA2	GATA binding protein 2	0.021
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.020
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.020
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.020
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.020
RAD50	RAD50 homolog (S. cerevisiae)	0.020
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.019
SOCS3	suppressor of cytokine signaling 3	0.019
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.018
SPRR2D	small proline-rich protein 2D	0.018
PTPRR	protein tyrosine phosphatase, receptor type, R	0.018
MAPK8	mitogen-activated protein kinase 8	0.018
DUSP7	dual specificity phosphatase 7	0.018
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.018
ATF2	activating transcription factor 2	0.018
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.017
TAL1	T-cell acute lymphocytic leukemia 1	0.017	Human
SOCS1	suppressor of cytokine signaling 1	0.017
MAPK12	mitogen-activated protein kinase 12	0.017
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.017
PRKCE	protein kinase C, epsilon	0.016	Human
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.016
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.015
RUNX1	runt-related transcription factor 1	0.015
DGCR14	DiGeorge syndrome critical region gene 14	0.015
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.015
SETD7	SET domain containing (lysine methyltransferase) 7	0.015
PARP1	poly (ADP-ribose) polymerase 1	0.015
NCOA3	nuclear receptor coactivator 3	0.014
SPTBN4	spectrin, beta, non-erythrocytic 4	0.014
MBNL1	muscleblind-like (Drosophila)	0.014
FNIP1	folliculin interacting protein 1	0.014
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.014
PEA15	phosphoprotein enriched in astrocytes 15	0.014
CLIP1	CAP-GLY domain containing linker protein 1	0.014
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.013
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.013
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.013
SIRT1	sirtuin 1	0.013
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.013
DNM2	dynamin 2	0.013
RPL39	ribosomal protein L39	0.013
EEF2K	eukaryotic elongation factor-2 kinase	0.013
FAM193B	family with sequence similarity 193, member B	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
HDAC6	histone deacetylase 6	0.013
GAS2L3	growth arrest-specific 2 like 3	0.013
CSNK2B	casein kinase 2, beta polypeptide	0.013
NCF4	neutrophil cytosolic factor 4, 40kDa	0.013
HDAC1	histone deacetylase 1	0.013
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.012
CYBA	cytochrome b-245, alpha polypeptide	0.012
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.012
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.012
PICALM	phosphatidylinositol binding clathrin assembly protein	0.012
PLD1	phospholipase D1, phosphatidylcholine-specific	0.012
FANCD2	Fanconi anemia, complementation group D2	0.012
CDK9	cyclin-dependent kinase 9	0.012
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.011
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.011
RPL41	ribosomal protein L41	0.011
ZNF282	zinc finger protein 282	0.011
RNF19A	ring finger protein 19A	0.011
CREB1	cAMP responsive element binding protein 1	0.011
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.011
C19orf46	chromosome 19 open reading frame 46	0.011
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.011
LMO2	LIM domain only 2 (rhombotin-like 1)	0.011
TRIM9	tripartite motif containing 9	0.011
TP53BP2	tumor protein p53 binding protein, 2	0.011
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.010
CDK17	cyclin-dependent kinase 17	0.010
CHUK	conserved helix-loop-helix ubiquitous kinase	0.010
ZNF746	zinc finger protein 746	0.010
VASP	vasodilator-stimulated phosphoprotein	0.010
TSC22D1	TSC22 domain family, member 1	0.010
CABLES1	Cdk5 and Abl enzyme substrate 1	0.010