IMP: Integrative Multi-species Prediction

Homo sapiens

35 genes annotated in human

positive regulation of translation

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of translation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of translation" (in gray)

Name	Description	Probability	Func Analog Organism
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.997
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.993
PABPC1	poly(A) binding protein, cytoplasmic 1	0.963
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.945
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.861	Fly
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.798
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.751
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.731
RBMX	RNA binding motif protein, X-linked	0.712
DAZ1	deleted in azoospermia 1	0.668
PBX1	pre-B-cell leukemia homeobox 1	0.659
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.658
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.651
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.602
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.588
RPS6	ribosomal protein S6	0.553
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.494
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.435	Fly
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.386
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.379	Human
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.379
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.347
MAPK3	mitogen-activated protein kinase 3	0.318	Rat
NCL	nucleolin	0.312
RBM8A	RNA binding motif protein 8A	0.311
EGFR	epidermal growth factor receptor	0.298	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.238	Human
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.235
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.207
GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.194
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.181
PAX3	paired box 3	0.180
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.178	Fly
SRSF3	serine/arginine-rich splicing factor 3	0.176
TRA2B	transformer 2 beta homolog (Drosophila)	0.176
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.176
TOB1	transducer of ERBB2, 1	0.151
BCL3	B-cell CLL/lymphoma 3	0.140
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.126
PCBP1	poly(rC) binding protein 1	0.125
RPS14	ribosomal protein S14	0.124
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.120
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.116
POU3F2	POU class 3 homeobox 2	0.115
RPS5	ribosomal protein S5	0.110
TNIP2	TNFAIP3 interacting protein 2	0.106
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.105
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.105
GSPT1	G1 to S phase transition 1	0.103	Yeast
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.102
PCBP2	poly(rC) binding protein 2	0.098
YBX1	Y box binding protein 1	0.097
USP9Y	ubiquitin specific peptidase 9, Y-linked	0.097
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.097	Human
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.095	Human
RPS28	ribosomal protein S28	0.089
TNRC6C	trinucleotide repeat containing 6C	0.089
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.086	Fly
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.083
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.082
MAPK14	mitogen-activated protein kinase 14	0.079
YY1	YY1 transcription factor	0.079
PAIP2	poly(A) binding protein interacting protein 2	0.076
RPS3	ribosomal protein S3	0.075
PTBP1	polypyrimidine tract binding protein 1	0.073
RPL11	ribosomal protein L11	0.072
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.072
RPL3	ribosomal protein L3	0.072
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.072
POU5F1	POU class 5 homeobox 1	0.068
RPS16	ribosomal protein S16	0.065
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.065
ILF3	interleukin enhancer binding factor 3, 90kDa	0.064
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.063
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.062
RPL28	ribosomal protein L28	0.061
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.060
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.059
SRSF2	serine/arginine-rich splicing factor 2	0.059
PTBP2	polypyrimidine tract binding protein 2	0.058
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.057
SNRPA	small nuclear ribonucleoprotein polypeptide A	0.056
DAZL	deleted in azoospermia-like	0.055
EEF2	eukaryotic translation elongation factor 2	0.055
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.055
MED25	mediator complex subunit 25	0.054
MAPT	microtubule-associated protein tau	0.053
TARDBP	TAR DNA binding protein	0.052
FBXO7	F-box protein 7	0.052
EEF2K	eukaryotic elongation factor-2 kinase	0.050
QKI	quaking homolog, KH domain RNA binding (mouse)	0.047	Human
SMS	spermine synthase	0.047
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.046
RSL1D1	ribosomal L1 domain containing 1	0.046
SYK	spleen tyrosine kinase	0.046
GAB2	GRB2-associated binding protein 2	0.045
IGF1R	insulin-like growth factor 1 receptor	0.044
DUSP1	dual specificity phosphatase 1	0.044
MAPK1	mitogen-activated protein kinase 1	0.044	Rat
RARA	retinoic acid receptor, alpha	0.043
EEF1A1	eukaryotic translation elongation factor 1 alpha 1	0.043
RPS18	ribosomal protein S18	0.043
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.042
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.041
RPL18	ribosomal protein L18	0.041
SRSF1	serine/arginine-rich splicing factor 1	0.039
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.039
GSK3B	glycogen synthase kinase 3 beta	0.039
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.038
SMAD7	SMAD family member 7	0.038
RPS23	ribosomal protein S23	0.038
PABPC3	poly(A) binding protein, cytoplasmic 3	0.037
MEIS2	Meis homeobox 2	0.037	Worm
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.035
ERH	enhancer of rudimentary homolog (Drosophila)	0.034
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.034
GLTSCR2	glioma tumor suppressor candidate region gene 2	0.033
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.032
ETF1	eukaryotic translation termination factor 1	0.032
SSRP1	structure specific recognition protein 1	0.032
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	0.032
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.032
RICTOR	RPTOR independent companion of MTOR, complex 2	0.031
ZFR	zinc finger RNA binding protein	0.031
COASY	CoA synthase	0.030
MEIS1	Meis homeobox 1	0.030	Worm
MATR3	matrin 3	0.030
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.030
THOC4	THO complex 4	0.030	Human
RPS19	ribosomal protein S19	0.029
EIF4A3	eukaryotic translation initiation factor 4A3	0.029
EIF1AX	eukaryotic translation initiation factor 1A, X-linked	0.029
KDM5D	lysine (K)-specific demethylase 5D	0.029
MAP2K1	mitogen-activated protein kinase kinase 1	0.028
UPF3A	UPF3 regulator of nonsense transcripts homolog A (yeast)	0.028
SFPQ	splicing factor proline/glutamine-rich	0.027
NCOA1	nuclear receptor coactivator 1	0.027
POLDIP3	polymerase (DNA-directed), delta interacting protein 3	0.027
CHUK	conserved helix-loop-helix ubiquitous kinase	0.027
SRSF9	serine/arginine-rich splicing factor 9	0.026
UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked	0.026
EEF1G	eukaryotic translation elongation factor 1 gamma	0.026
TSC2	tuberous sclerosis 2	0.026
LAT	linker for activation of T cells	0.026
RPL10	ribosomal protein L10	0.025
MPRIP	myosin phosphatase Rho interacting protein	0.024
EIF4A1	eukaryotic translation initiation factor 4A1	0.024
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.023
MARCKSL1	MARCKS-like 1	0.023
HDGF	hepatoma-derived growth factor	0.023
RPTOR	regulatory associated protein of MTOR, complex 1	0.023
PRMT1	protein arginine methyltransferase 1	0.023
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.022
RPL4	ribosomal protein L4	0.022
CELF1	CUGBP, Elav-like family member 1	0.022
C19orf46	chromosome 19 open reading frame 46	0.022
RPS10	ribosomal protein S10	0.022
NFIB	nuclear factor I/B	0.020
SRPK1	SRSF protein kinase 1	0.020
PDPK1	3-phosphoinositide dependent protein kinase-1	0.020
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.020
CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	0.020
RPL8	ribosomal protein L8	0.020
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.020	Human
SALL2	sal-like 2 (Drosophila)	0.020
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.020
CIRBP	cold inducible RNA binding protein	0.020
MEOX2	mesenchyme homeobox 2	0.020
FAU	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	0.020
FAM46A	family with sequence similarity 46, member A	0.019
NCBP2	nuclear cap binding protein subunit 2, 20kDa	0.019
HPS6	Hermansky-Pudlak syndrome 6	0.019
WT1	Wilms tumor 1	0.019
RPL12	ribosomal protein L12	0.019
MATK	megakaryocyte-associated tyrosine kinase	0.019
RBM3	RNA binding motif (RNP1, RRM) protein 3	0.019	Human Rat
FYN	FYN oncogene related to SRC, FGR, YES	0.019
RPS15	ribosomal protein S15	0.018
GAB1	GRB2-associated binding protein 1	0.018
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.018
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.018
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.018
FOXD3	forkhead box D3	0.018
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.018	Mouse
LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.017
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.017
ARRB2	arrestin, beta 2	0.017
C12orf62	chromosome 12 open reading frame 62	0.017
ILF2	interleukin enhancer binding factor 2, 45kDa	0.017
INO80	INO80 homolog (S. cerevisiae)	0.017
GSPT2	G1 to S phase transition 2	0.016	Yeast
DDR2	discoidin domain receptor tyrosine kinase 2	0.016
CUL5	cullin 5	0.016
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.016
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.016
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.016
RPL7A	ribosomal protein L7a	0.016
PPM1G	protein phosphatase, Mg2+/Mn2+ dependent, 1G	0.016
FZD5	frizzled homolog 5 (Drosophila)	0.016
MYL12B	myosin, light chain 12B, regulatory	0.016
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.016
KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	0.016	Human
MPP1	membrane protein, palmitoylated 1, 55kDa	0.016
NONO	non-POU domain containing, octamer-binding	0.016
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.016
NHP2	NHP2 ribonucleoprotein homolog (yeast)	0.016
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.016
TRO	trophinin	0.016
CREB1	cAMP responsive element binding protein 1	0.016
AXL	AXL receptor tyrosine kinase	0.015
PRKCZ	protein kinase C, zeta	0.015
RTCD1	RNA terminal phosphate cyclase domain 1	0.015
RPLP1	ribosomal protein, large, P1	0.015
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.015
SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	0.015
SRSF5	serine/arginine-rich splicing factor 5	0.015
DLG2	discs, large homolog 2 (Drosophila)	0.015
RPL13	ribosomal protein L13	0.015
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.015
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.014
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.014
ATXN2	ataxin 2	0.014
ARIH2	ariadne homolog 2 (Drosophila)	0.014
UFM1	ubiquitin-fold modifier 1	0.014
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.014
HMGN1	high mobility group nucleosome binding domain 1	0.014
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.014
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.014
ZNF746	zinc finger protein 746	0.014
AHCY	adenosylhomocysteinase	0.014
HOXA9	homeobox A9	0.014
PABPN1	poly(A) binding protein, nuclear 1	0.014
PRKCA	protein kinase C, alpha	0.014
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.014
RPS12	ribosomal protein S12	0.013
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.013
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.013	Human
UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.013
DCAF17	DDB1 and CUL4 associated factor 17	0.013
SOS1	son of sevenless homolog 1 (Drosophila)	0.013
MYH10	myosin, heavy chain 10, non-muscle	0.013
RPLP2	ribosomal protein, large, P2	0.013
RPS4Y1	ribosomal protein S4, Y-linked 1	0.013	Human
C10orf116	chromosome 10 open reading frame 116	0.013
RPL5	ribosomal protein L5	0.013
HMGA1	high mobility group AT-hook 1	0.013
SOX11	SRY (sex determining region Y)-box 11	0.013	Human
DLG4	discs, large homolog 4 (Drosophila)	0.013
BOLL	bol, boule-like (Drosophila)	0.013
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.013
PRKCQ	protein kinase C, theta	0.013
CNBP	CCHC-type zinc finger, nucleic acid binding protein	0.012	Yeast
CUL1	cullin 1	0.012
PML	promyelocytic leukemia	0.012
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.012
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.012
CREBBP	CREB binding protein	0.012
EIF4EBP3	eukaryotic translation initiation factor 4E binding protein 3	0.012
ZFY	zinc finger protein, Y-linked	0.012
TELO2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.012
RPA3	replication protein A3, 14kDa	0.012
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.012
INSR	insulin receptor	0.012
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.012
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.012
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.012
CYorf15A	chromosome Y open reading frame 15A	0.012
ALAS1	aminolevulinate, delta-, synthase 1	0.012
NDUFC2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa	0.012
FBXO33	F-box protein 33	0.012
TNIP1	TNFAIP3 interacting protein 1	0.011
MAST1	microtubule associated serine/threonine kinase 1	0.011
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.011
VAV3	vav 3 guanine nucleotide exchange factor	0.011
SH3BP2	SH3-domain binding protein 2	0.011
RPS2	ribosomal protein S2	0.011	Yeast
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.011
DUSP3	dual specificity phosphatase 3	0.011
HMGN2	high mobility group nucleosomal binding domain 2	0.011
RPL23	ribosomal protein L23	0.011
EP300	E1A binding protein p300	0.011
DUSP7	dual specificity phosphatase 7	0.011
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.011
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.011	Human
WWOX	WW domain containing oxidoreductase	0.011
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.011
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.011
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.011
TOP1	topoisomerase (DNA) I	0.011
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.011
POLR2F	polymerase (RNA) II (DNA directed) polypeptide F	0.011
SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	0.011
FOXG1	forkhead box G1	0.011
CMIP	c-Maf-inducing protein	0.011
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.011	Human
TGFB1	transforming growth factor, beta 1	0.011
NPM3	nucleophosmin/nucleoplasmin 3	0.011	Human
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.011
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.010
PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	0.010
C20orf20	chromosome 20 open reading frame 20	0.010
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.010
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.010
KHSRP	KH-type splicing regulatory protein	0.010
FGFR1	fibroblast growth factor receptor 1	0.010
EIF5	eukaryotic translation initiation factor 5	0.010
SOX5	SRY (sex determining region Y)-box 5	0.010
ZBTB7A	zinc finger and BTB domain containing 7A	0.010
ZMAT3	zinc finger, matrin-type 3	0.010
KIAA0930	KIAA0930	0.010
SURF1	surfeit 1	0.010
MRPL11	mitochondrial ribosomal protein L11	0.010
DHX34	DEAH (Asp-Glu-Ala-His) box polypeptide 34	0.010
RPS7	ribosomal protein S7	0.010
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.010
YAP1	Yes-associated protein 1	0.010
CNOT7	CCR4-NOT transcription complex, subunit 7	0.010
OPTN	optineurin	0.010
FASTKD2	FAST kinase domains 2	0.010
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.010	Fly
POLR2H	polymerase (RNA) II (DNA directed) polypeptide H	0.010