IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

establishment of planar polarity

Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment of planar polarity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "establishment of planar polarity" (in gray)

Name	Description	Probability	Func Analog Organism
ARHGAP1	Rho GTPase activating protein 1	0.983
RHOA	ras homolog gene family, member A	0.959	Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.947
GDA	guanine deaminase	0.873
LRRK2	leucine-rich repeat kinase 2	0.650
TPBG	trophoblast glycoprotein	0.632
AFF4	AF4/FMR2 family, member 4	0.558
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.543
AFF1	AF4/FMR2 family, member 1	0.513
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.459
RIN1	Ras and Rab interactor 1	0.415
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.413
APC	adenomatous polyposis coli	0.389
PTN	pleiotrophin	0.366
KRT5	keratin 5	0.361
EGFR	epidermal growth factor receptor	0.356	Fly
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.336	Mouse Fly
CABLES1	Cdk5 and Abl enzyme substrate 1	0.315
TSG101	tumor susceptibility gene 101	0.276
PRKCZ	protein kinase C, zeta	0.271
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.257
SEC23A	Sec23 homolog A (S. cerevisiae)	0.253
INVS	inversin	0.248
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.229
JUP	junction plakoglobin	0.220
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.211
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.206
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.200
FZD1	frizzled homolog 1 (Drosophila)	0.186	Mouse
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.181
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.178
NCKAP1	NCK-associated protein 1	0.171
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.168
SMAD2	SMAD family member 2	0.162
SATB2	SATB homeobox 2	0.160
EZR	ezrin	0.154
AXIN1	axin 1	0.151
WNT3A	wingless-type MMTV integration site family, member 3A	0.149
SOX4	SRY (sex determining region Y)-box 4	0.149
SORBS3	sorbin and SH3 domain containing 3	0.147
MYO6	myosin VI	0.139
CSNK1E	casein kinase 1, epsilon	0.135	Fly
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.129
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.126
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.124
JAM2	junctional adhesion molecule 2	0.123
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.120
CEP164	centrosomal protein 164kDa	0.119
TTC30B	tetratricopeptide repeat domain 30B	0.119
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.116
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.115
PRKCI	protein kinase C, iota	0.113
MED29	mediator complex subunit 29	0.113
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.113
WNT5A	wingless-type MMTV integration site family, member 5A	0.111	Mouse Rat
TYRP1	tyrosinase-related protein 1	0.109
JUB	jub, ajuba homolog (Xenopus laevis)	0.107
LRP6	low density lipoprotein receptor-related protein 6	0.107
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.105
CSNK1D	casein kinase 1, delta	0.105	Fly
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.103
CAV1	caveolin 1, caveolae protein, 22kDa	0.101
MED24	mediator complex subunit 24	0.101
WT1	Wilms tumor 1	0.100
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.100
BCL6	B-cell CLL/lymphoma 6	0.098
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.098
CFL1	cofilin 1 (non-muscle)	0.096
TJP2	tight junction protein 2 (zona occludens 2)	0.096
CAPN1	calpain 1, (mu/I) large subunit	0.095
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.094	Fly
MAP2K6	mitogen-activated protein kinase kinase 6	0.092
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.092
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.090
PTPRF	protein tyrosine phosphatase, receptor type, F	0.089
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.089
GSK3B	glycogen synthase kinase 3 beta	0.088
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.087	Fly
SH3RF3	SH3 domain containing ring finger 3	0.086
BAK1	BCL2-antagonist/killer 1	0.085
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.084
TRIP6	thyroid hormone receptor interactor 6	0.083
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.082
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.081
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.080
SMAD1	SMAD family member 1	0.075
MAPT	microtubule-associated protein tau	0.075
ABI2	abl-interactor 2	0.073
WASF1	WAS protein family, member 1	0.072
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.071
CDH5	cadherin 5, type 2 (vascular endothelium)	0.069
HIPK3	homeodomain interacting protein kinase 3	0.067
SFN	stratifin	0.064
CDK6	cyclin-dependent kinase 6	0.063
CCNT1	cyclin T1	0.062
IQGAP1	IQ motif containing GTPase activating protein 1	0.060
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.059
ERBB2IP	erbb2 interacting protein	0.059
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.059
TGFBR1	transforming growth factor, beta receptor 1	0.057
UBE3A	ubiquitin protein ligase E3A	0.057
MUC1	mucin 1, cell surface associated	0.055
RDX	radixin	0.054
GRB7	growth factor receptor-bound protein 7	0.054
FZD8	frizzled homolog 8 (Drosophila)	0.054
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.053
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.053
BAHD1	bromo adjacent homology domain containing 1	0.053
ACTB	actin, beta	0.051
HDAC9	histone deacetylase 9	0.051
F11R	F11 receptor	0.050
SERINC1	serine incorporator 1	0.050
UBQLN2	ubiquilin 2	0.049
MAVS	mitochondrial antiviral signaling protein	0.049
YAP1	Yes-associated protein 1	0.048
USP21	ubiquitin specific peptidase 21	0.048
ANTXR2	anthrax toxin receptor 2	0.047
JAM3	junctional adhesion molecule 3	0.047
CDK19	cyclin-dependent kinase 19	0.047
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.046
DAAM1	dishevelled associated activator of morphogenesis 1	0.046
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.045
ZEB2	zinc finger E-box binding homeobox 2	0.044
MCC	mutated in colorectal cancers	0.044
ABI1	abl-interactor 1	0.044
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.044
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.044
CPSF1	cleavage and polyadenylation specific factor 1, 160kDa	0.044
PITX1	paired-like homeodomain 1	0.044
TIMP2	TIMP metallopeptidase inhibitor 2	0.044
BASP1	brain abundant, membrane attached signal protein 1	0.043
ZNF512B	zinc finger protein 512B	0.043
SH2D3A	SH2 domain containing 3A	0.043
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.043	Fly
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.042
BCAR1	breast cancer anti-estrogen resistance 1	0.042
C9orf100	chromosome 9 open reading frame 100	0.042
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.042	Fly
CD164	CD164 molecule, sialomucin	0.042
CHN2	chimerin (chimaerin) 2	0.042
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.042
APLP2	amyloid beta (A4) precursor-like protein 2	0.041
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.041
SFRP1	secreted frizzled-related protein 1	0.040	Mouse
FERMT2	fermitin family member 2	0.040
MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	0.040
FGFR1	fibroblast growth factor receptor 1	0.040
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.040
TGFBR3	transforming growth factor, beta receptor III	0.039
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.039
SDC4	syndecan 4	0.039
CDK9	cyclin-dependent kinase 9	0.038
ZNF408	zinc finger protein 408	0.038
KRT6C	keratin 6C	0.038
SMAD3	SMAD family member 3	0.037
SRI	sorcin	0.037
GJA1	gap junction protein, alpha 1, 43kDa	0.037
TMEM30A	transmembrane protein 30A	0.037
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.036
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.036
SEC24A	SEC24 family, member A (S. cerevisiae)	0.036
IFNGR1	interferon gamma receptor 1	0.036
STAT5B	signal transducer and activator of transcription 5B	0.035
TNS3	tensin 3	0.034
SASH1	SAM and SH3 domain containing 1	0.034
STAT2	signal transducer and activator of transcription 2, 113kDa	0.034
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.033
SYNJ2	synaptojanin 2	0.033
MYO1C	myosin IC	0.033
SETD7	SET domain containing (lysine methyltransferase) 7	0.033
MARK2	MAP/microtubule affinity-regulating kinase 2	0.033
DEDD	death effector domain containing	0.033
RAB5B	RAB5B, member RAS oncogene family	0.033
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.032
LAD1	ladinin 1	0.032
KAT2A	K(lysine) acetyltransferase 2A	0.032
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.032
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.032	Fly
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.032
FYN	FYN oncogene related to SRC, FGR, YES	0.032
ZMYND11	zinc finger, MYND-type containing 11	0.032
TRO	trophinin	0.031
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.031
PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.031
ADAM9	ADAM metallopeptidase domain 9	0.031
VAV2	vav 2 guanine nucleotide exchange factor	0.031
SSH1	slingshot homolog 1 (Drosophila)	0.031
ELL2	elongation factor, RNA polymerase II, 2	0.030
EAF1	ELL associated factor 1	0.030
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.030
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.030
JAK1	Janus kinase 1	0.030	Fly
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.030
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.030
SHROOM3	shroom family member 3	0.030
LRP2	low density lipoprotein receptor-related protein 2	0.030
IGSF21	immunoglobin superfamily, member 21	0.030
PDCD6IP	programmed cell death 6 interacting protein	0.030
UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	0.030
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.029
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.029
SEC24D	SEC24 family, member D (S. cerevisiae)	0.029
TNS4	tensin 4	0.029
RHOG	ras homolog gene family, member G (rho G)	0.029
HSF1	heat shock transcription factor 1	0.029
ZMYM3	zinc finger, MYM-type 3	0.029
LMNA	lamin A/C	0.029
NCKIPSD	NCK interacting protein with SH3 domain	0.029
NKD2	naked cuticle homolog 2 (Drosophila)	0.029
RTKN	rhotekin	0.029
PIAS3	protein inhibitor of activated STAT, 3	0.029
ADRB2	adrenergic, beta-2-, receptor, surface	0.029
TIFA	TRAF-interacting protein with forkhead-associated domain	0.028
GATAD2B	GATA zinc finger domain containing 2B	0.028
KIAA1522	KIAA1522	0.028
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.028
MTMR4	myotubularin related protein 4	0.028
TMEM123	transmembrane protein 123	0.028
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.028
SORBS2	sorbin and SH3 domain containing 2	0.028
KCTD12	potassium channel tetramerisation domain containing 12	0.028
PKP3	plakophilin 3	0.028
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.027
MSH5	mutS homolog 5 (E. coli)	0.027
ELL3	elongation factor RNA polymerase II-like 3	0.027
ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19	0.027
F2R	coagulation factor II (thrombin) receptor	0.027
ATXN1	ataxin 1	0.027
SH3KBP1	SH3-domain kinase binding protein 1	0.027
COL12A1	collagen, type XII, alpha 1	0.027
ELL	elongation factor RNA polymerase II	0.027
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.027
EDNRB	endothelin receptor type B	0.026
FAM176A	family with sequence similarity 176, member A	0.026
SIAH2	seven in absentia homolog 2 (Drosophila)	0.026
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.026
ZBTB8A	zinc finger and BTB domain containing 8A	0.026
MED14	mediator complex subunit 14	0.026
BRD4	bromodomain containing 4	0.026
BMP7	bone morphogenetic protein 7	0.026
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.026
MED26	mediator complex subunit 26	0.026
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.026	Fly
C16orf48	chromosome 16 open reading frame 48	0.026
HES1	hairy and enhancer of split 1, (Drosophila)	0.026
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.025
MSN	moesin	0.025
ADAM19	ADAM metallopeptidase domain 19	0.025
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.025
RGL1	ral guanine nucleotide dissociation stimulator-like 1	0.025
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.025
GPC4	glypican 4	0.025
CLDN7	claudin 7	0.025
CAV2	caveolin 2	0.025
CREBBP	CREB binding protein	0.025
DTX2	deltex homolog 2 (Drosophila)	0.025
ZFYVE9	zinc finger, FYVE domain containing 9	0.025
PEA15	phosphoprotein enriched in astrocytes 15	0.025
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.025
INADL	InaD-like (Drosophila)	0.024
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.024
BICD1	bicaudal D homolog 1 (Drosophila)	0.024
PNMA2	paraneoplastic antigen MA2	0.024
TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	0.024
C5orf55	chromosome 5 open reading frame 55	0.024
AMOTL1	angiomotin like 1	0.024
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.024
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.024
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.024
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.024
LAPTM4A	lysosomal protein transmembrane 4 alpha	0.024
MAPK14	mitogen-activated protein kinase 14	0.024
ACTG1	actin, gamma 1	0.024
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.024
FZD7	frizzled homolog 7 (Drosophila)	0.024
SIAH1	seven in absentia homolog 1 (Drosophila)	0.024
TPM1	tropomyosin 1 (alpha)	0.024
C1orf106	chromosome 1 open reading frame 106	0.023
MAP1B	microtubule-associated protein 1B	0.023
USP5	ubiquitin specific peptidase 5 (isopeptidase T)	0.023
DPYSL2	dihydropyrimidinase-like 2	0.023
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.023
SSBP3	single stranded DNA binding protein 3	0.023
ARHGAP21	Rho GTPase activating protein 21	0.023
CNN3	calponin 3, acidic	0.023
BAI1	brain-specific angiogenesis inhibitor 1	0.023
GLIS2	GLIS family zinc finger 2	0.023
WASF2	WAS protein family, member 2	0.023
TJP1	tight junction protein 1 (zona occludens 1)	0.023
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.023
FOXF1	forkhead box F1	0.023
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.023
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.023
NIN	ninein (GSK3B interacting protein)	0.023
FOXC1	forkhead box C1	0.023
HMGA1	high mobility group AT-hook 1	0.023
RBM11	RNA binding motif protein 11	0.023
TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.023
KIAA1644	KIAA1644	0.023
FER	fer (fps/fes related) tyrosine kinase	0.023
SOCS1	suppressor of cytokine signaling 1	0.023
PSAP	prosaposin	0.023
VANGL2	vang-like 2 (van gogh, Drosophila)	0.022	Mouse
LITAF	lipopolysaccharide-induced TNF factor	0.022
GTF2IRD1	GTF2I repeat domain containing 1	0.022
ITM2B	integral membrane protein 2B	0.022
FRK	fyn-related kinase	0.022
TRAF4	TNF receptor-associated factor 4	0.022
ST5	suppression of tumorigenicity 5	0.022
CTNND1	catenin (cadherin-associated protein), delta 1	0.022
CREB3	cAMP responsive element binding protein 3	0.022
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.022
STAT5A	signal transducer and activator of transcription 5A	0.022
LRP4	low density lipoprotein receptor-related protein 4	0.022
PRRC2B	proline-rich coiled-coil 2B	0.022
DOCK9	dedicator of cytokinesis 9	0.022
RANBP9	RAN binding protein 9	0.022
C5orf13	chromosome 5 open reading frame 13	0.022
SNAI2	snail homolog 2 (Drosophila)	0.022
LGR4	leucine-rich repeat containing G protein-coupled receptor 4	0.022
TWIST1	twist homolog 1 (Drosophila)	0.022
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.022
KDM5C	lysine (K)-specific demethylase 5C	0.022
RHPN2	rhophilin, Rho GTPase binding protein 2	0.022
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.022
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.022
GATA5	GATA binding protein 5	0.021
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.021
ZNF676	zinc finger protein 676	0.021
ARF3	ADP-ribosylation factor 3	0.021
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.021
NCK1	NCK adaptor protein 1	0.021
MED13	mediator complex subunit 13	0.021
SH3RF1	SH3 domain containing ring finger 1	0.021
TUBA1A	tubulin, alpha 1a	0.021
FOXQ1	forkhead box Q1	0.021
DPPA2	developmental pluripotency associated 2	0.021
PCDH7	protocadherin 7	0.021
USP11	ubiquitin specific peptidase 11	0.021
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.021
NEO1	neogenin 1	0.021
TPD52L1	tumor protein D52-like 1	0.021
FAM193A	family with sequence similarity 193, member A	0.021
DOK4	docking protein 4	0.021
RAD52	RAD52 homolog (S. cerevisiae)	0.021
FAS	Fas (TNF receptor superfamily, member 6)	0.021
MORC4	MORC family CW-type zinc finger 4	0.021
DBN1	drebrin 1	0.021
RAB1A	RAB1A, member RAS oncogene family	0.021
HSPB1	heat shock 27kDa protein 1	0.021
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.021
FZD10	frizzled homolog 10 (Drosophila)	0.021
SYT11	synaptotagmin XI	0.021
EID3	EP300 interacting inhibitor of differentiation 3	0.020
TAGLN2	transgelin 2	0.020
PBX1	pre-B-cell leukemia homeobox 1	0.020
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.020
AXIN2	axin 2	0.020
KLHL12	kelch-like 12 (Drosophila)	0.020
RAB14	RAB14, member RAS oncogene family	0.020
WIF1	WNT inhibitory factor 1	0.020
NES	nestin	0.020
PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	0.020
MYST2	MYST histone acetyltransferase 2	0.020
CAPRIN2	caprin family member 2	0.020
LIMK2	LIM domain kinase 2	0.020	Fly
FAM110C	family with sequence similarity 110, member C	0.020
CPNE3	copine III	0.020
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.020
SHB	Src homology 2 domain containing adaptor protein B	0.020
DAPK1	death-associated protein kinase 1	0.020
FAM198B	family with sequence similarity 198, member B	0.020
EDNRA	endothelin receptor type A	0.020
PMP22	peripheral myelin protein 22	0.020
PRKCDBP	protein kinase C, delta binding protein	0.020
NRG1	neuregulin 1	0.020
MARK1	MAP/microtubule affinity-regulating kinase 1	0.020
RBP1	retinol binding protein 1, cellular	0.020
RADIL	Ras association and DIL domains	0.020
TP73	tumor protein p73	0.020
RPAP1	RNA polymerase II associated protein 1	0.020
GNS	glucosamine (N-acetyl)-6-sulfatase	0.020
TLN2	talin 2	0.020
SOS1	son of sevenless homolog 1 (Drosophila)	0.020
MATN2	matrilin 2	0.020
OGDHL	oxoglutarate dehydrogenase-like	0.020
TMEM98	transmembrane protein 98	0.020
GIGYF2	GRB10 interacting GYF protein 2	0.019
TRAM2	translocation associated membrane protein 2	0.019
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.019
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.019
NPTN	neuroplastin	0.019
NPEPPS	aminopeptidase puromycin sensitive	0.019
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.019
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.019
ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5	0.019
GNE	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	0.019
MAP4	microtubule-associated protein 4	0.019
DST	dystonin	0.019
FZD6	frizzled homolog 6 (Drosophila)	0.019	Mouse
FZD2	frizzled homolog 2 (Drosophila)	0.019
NOTCH1	notch 1	0.019
PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha	0.019
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.019
JAK2	Janus kinase 2	0.019	Fly
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.019
AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.019
ITSN2	intersectin 2	0.019
GPM6B	glycoprotein M6B	0.019
PFN1	profilin 1	0.019
KIAA1033	KIAA1033	0.019
FGD1	FYVE, RhoGEF and PH domain containing 1	0.019
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.019
RND3	Rho family GTPase 3	0.019
MSH4	mutS homolog 4 (E. coli)	0.019
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.019
TBC1D14	TBC1 domain family, member 14	0.019
COLEC12	collectin sub-family member 12	0.019
MBD5	methyl-CpG binding domain protein 5	0.019
AMOTL2	angiomotin like 2	0.019
DFNA5	deafness, autosomal dominant 5	0.019
ERRFI1	ERBB receptor feedback inhibitor 1	0.019
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.019
NFIB	nuclear factor I/B	0.019
FBRSL1	fibrosin-like 1	0.018
RIN2	Ras and Rab interactor 2	0.018
PHF10	PHD finger protein 10	0.018
DOCK8	dedicator of cytokinesis 8	0.018
MNX1	motor neuron and pancreas homeobox 1	0.018
SALL1	sal-like 1 (Drosophila)	0.018
SUSD4	sushi domain containing 4	0.018
RBP4	retinol binding protein 4, plasma	0.018
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.018
DDI1	DNA-damage inducible 1 homolog 1 (S. cerevisiae)	0.018
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.018
RNF139	ring finger protein 139	0.018
SIPA1L3	signal-induced proliferation-associated 1 like 3	0.018
TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	0.018
USH1C	Usher syndrome 1C (autosomal recessive, severe)	0.018
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.018
VCL	vinculin	0.018
COL4A6	collagen, type IV, alpha 6	0.018
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.018
WNT5B	wingless-type MMTV integration site family, member 5B	0.018
PERP	PERP, TP53 apoptosis effector	0.018
LPHN3	latrophilin 3	0.018
GAS1	growth arrest-specific 1	0.018
RAP1B	RAP1B, member of RAS oncogene family	0.018	Fly
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.018
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.018
DOCK1	dedicator of cytokinesis 1	0.018
BRD3	bromodomain containing 3	0.018
PID1	phosphotyrosine interaction domain containing 1	0.018
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.018
CAPNS1	calpain, small subunit 1	0.018
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.018
CC2D1A	coiled-coil and C2 domain containing 1A	0.018
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.018
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.018
INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	0.018
DLC1	deleted in liver cancer 1	0.018
WNT4	wingless-type MMTV integration site family, member 4	0.018
CGN	cingulin	0.018
PCSK5	proprotein convertase subtilisin/kexin type 5	0.018
GPR56	G protein-coupled receptor 56	0.018
LAMP1	lysosomal-associated membrane protein 1	0.018
GPR161	G protein-coupled receptor 161	0.018
PTK6	PTK6 protein tyrosine kinase 6	0.018
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.018
ACVR2B	activin A receptor, type IIB	0.018
HOXA9	homeobox A9	0.018
WWTR1	WW domain containing transcription regulator 1	0.018
SH3BP2	SH3-domain binding protein 2	0.018
TMEM47	transmembrane protein 47	0.018
CUL7	cullin 7	0.018
MN1	meningioma (disrupted in balanced translocation) 1	0.017
RPRD2	regulation of nuclear pre-mRNA domain containing 2	0.017
KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	0.017
BCHE	butyrylcholinesterase	0.017
SEC31A	SEC31 homolog A (S. cerevisiae)	0.017
FNDC1	fibronectin type III domain containing 1	0.017
STK38	serine/threonine kinase 38	0.017
USP46	ubiquitin specific peptidase 46	0.017
TEAD3	TEA domain family member 3	0.017
RAPGEFL1	Rap guanine nucleotide exchange factor (GEF)-like 1	0.017
COL9A3	collagen, type IX, alpha 3	0.017
RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	0.017
SFRP2	secreted frizzled-related protein 2	0.017	Mouse
GYG2	glycogenin 2	0.017
OLFM1	olfactomedin 1	0.017
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.017
SNCAIP	synuclein, alpha interacting protein	0.017
FLNB	filamin B, beta	0.017
TXNRD1	thioredoxin reductase 1	0.017
HIAT1	hippocampus abundant transcript 1	0.017
ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	0.017
RUSC1	RUN and SH3 domain containing 1	0.017
ZNF165	zinc finger protein 165	0.017
MATK	megakaryocyte-associated tyrosine kinase	0.017
FAM110A	family with sequence similarity 110, member A	0.017
MEIS2	Meis homeobox 2	0.017
LAMA5	laminin, alpha 5	0.017
EYA2	eyes absent homolog 2 (Drosophila)	0.017
PEG10	paternally expressed 10	0.017
CADM1	cell adhesion molecule 1	0.017
ITIH5	inter-alpha (globulin) inhibitor H5	0.017
HES6	hairy and enhancer of split 6 (Drosophila)	0.017
DIAPH1	diaphanous homolog 1 (Drosophila)	0.017
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.017
PLS3	plastin 3	0.017
KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	0.017
WBP5	WW domain binding protein 5	0.017
PTPRG	protein tyrosine phosphatase, receptor type, G	0.017
DAZAP2	DAZ associated protein 2	0.017
TDGF1	teratocarcinoma-derived growth factor 1	0.017
CCDC88A	coiled-coil domain containing 88A	0.017
TAGLN	transgelin	0.017
LAMA4	laminin, alpha 4	0.017
TRAM1	translocation associated membrane protein 1	0.017
DOK6	docking protein 6	0.017
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.017
FAM110B	family with sequence similarity 110, member B	0.017
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.017
TMEM9B	TMEM9 domain family, member B	0.017
IL13RA1	interleukin 13 receptor, alpha 1	0.016
PTGFRN	prostaglandin F2 receptor negative regulator	0.016
WHSC2	Wolf-Hirschhorn syndrome candidate 2	0.016
SBK1	SH3-binding domain kinase 1	0.016
PDE8A	phosphodiesterase 8A	0.016
TBX3	T-box 3	0.016
PODXL	podocalyxin-like	0.016
FSTL1	follistatin-like 1	0.016
ETV4	ets variant 4	0.016
NGEF	neuronal guanine nucleotide exchange factor	0.016
MYO1B	myosin IB	0.016
ACTN1	actinin, alpha 1	0.016
TEAD2	TEA domain family member 2	0.016
ZNRF3	zinc and ring finger 3	0.016	Mouse
ARHGAP32	Rho GTPase activating protein 32	0.016
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.016
PIKFYVE	phosphoinositide kinase, FYVE finger containing	0.016
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.016
GSTT1	glutathione S-transferase theta 1	0.016
SOX9	SRY (sex determining region Y)-box 9	0.016
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.016
FAM46D	family with sequence similarity 46, member D	0.016
TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	0.016
ZBTB39	zinc finger and BTB domain containing 39	0.016
RGL2	ral guanine nucleotide dissociation stimulator-like 2	0.016
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.016
FBXO46	F-box protein 46	0.016
MED20	mediator complex subunit 20	0.016
SLIT2	slit homolog 2 (Drosophila)	0.016
BNC2	basonuclin 2	0.016
BCL9	B-cell CLL/lymphoma 9	0.016
MSX2	msh homeobox 2	0.016
FOXL2	forkhead box L2	0.016
SYNGR3	synaptogyrin 3	0.016
GPS2	G protein pathway suppressor 2	0.016
CYTH3	cytohesin 3	0.016
PKN2	protein kinase N2	0.016
OCRL	oculocerebrorenal syndrome of Lowe	0.016
RAB9A	RAB9A, member RAS oncogene family	0.016
KCTD15	potassium channel tetramerisation domain containing 15	0.016
CCND1	cyclin D1	0.016
PTK7	PTK7 protein tyrosine kinase 7	0.016	Mouse
CDON	Cdon homolog (mouse)	0.016
TRPS1	trichorhinophalangeal syndrome I	0.016
MYADM	myeloid-associated differentiation marker	0.016
PRCP	prolylcarboxypeptidase (angiotensinase C)	0.016
COL2A1	collagen, type II, alpha 1	0.016
MID1	midline 1 (Opitz/BBB syndrome)	0.016
KIAA1683	KIAA1683	0.016
EFS	embryonal Fyn-associated substrate	0.016
MYH10	myosin, heavy chain 10, non-muscle	0.016
FAM92A1	family with sequence similarity 92, member A1	0.016
NXN	nucleoredoxin	0.016
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.016
WWC3	WWC family member 3	0.016
B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)	0.016
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.016
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.016
C1orf93	chromosome 1 open reading frame 93	0.016
USP43	ubiquitin specific peptidase 43	0.016
BAD	BCL2-associated agonist of cell death	0.016
VASH2	vasohibin 2	0.016
RBM4B	RNA binding motif protein 4B	0.016
PLD1	phospholipase D1, phosphatidylcholine-specific	0.016
EYA4	eyes absent homolog 4 (Drosophila)	0.016
FJX1	four jointed box 1 (Drosophila)	0.016
SYNGAP1	synaptic Ras GTPase activating protein 1	0.016
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.016
PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	0.016
QPCT	glutaminyl-peptide cyclotransferase	0.016
EXT1	exostosin 1	0.016
HMCN1	hemicentin 1	0.016
FAM105B	family with sequence similarity 105, member B	0.016
TAOK1	TAO kinase 1	0.016
PRICKLE1	prickle homolog 1 (Drosophila)	0.016	Fly
HOXA1	homeobox A1	0.016
FLRT2	fibronectin leucine rich transmembrane protein 2	0.016
IFT140	intraflagellar transport 140 homolog (Chlamydomonas)	0.016
MAGED1	melanoma antigen family D, 1	0.016
KIAA1543	KIAA1543	0.016
BEX1	brain expressed, X-linked 1	0.016
RAB5C	RAB5C, member RAS oncogene family	0.016
ZNF331	zinc finger protein 331	0.016
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	0.016
PICALM	phosphatidylinositol binding clathrin assembly protein	0.016
NUMA1	nuclear mitotic apparatus protein 1	0.016
ZBED1	zinc finger, BED-type containing 1	0.016
NRP1	neuropilin 1	0.016
APCDD1	adenomatosis polyposis coli down-regulated 1	0.016
PLAT	plasminogen activator, tissue	0.016
HHIP	hedgehog interacting protein	0.016
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.016
RIPK2	receptor-interacting serine-threonine kinase 2	0.016
RNF111	ring finger protein 111	0.015
NCKAP5	NCK-associated protein 5	0.015
TRDMT1	tRNA aspartic acid methyltransferase 1	0.015
H2AFY2	H2A histone family, member Y2	0.015
RANBP10	RAN binding protein 10	0.015
NINL	ninein-like	0.015
STOX2	storkhead box 2	0.015
FHL1	four and a half LIM domains 1	0.015
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.015
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.015
TTC30A	tetratricopeptide repeat domain 30A	0.015
MYO10	myosin X	0.015
TMEM39B	transmembrane protein 39B	0.015
ZNF142	zinc finger protein 142	0.015
SPTBN2	spectrin, beta, non-erythrocytic 2	0.015
HOXD8	homeobox D8	0.015
ZEB1	zinc finger E-box binding homeobox 1	0.015
CDS2	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	0.015
FZD5	frizzled homolog 5 (Drosophila)	0.015
ZFP28	zinc finger protein 28 homolog (mouse)	0.015
TNFRSF19	tumor necrosis factor receptor superfamily, member 19	0.015
PTCH1	patched 1	0.015
SPON1	spondin 1, extracellular matrix protein	0.015
SIPA1L1	signal-induced proliferation-associated 1 like 1	0.015
CRTAP	cartilage associated protein	0.015
ARL3	ADP-ribosylation factor-like 3	0.015
LIMCH1	LIM and calponin homology domains 1	0.015
RIPK4	receptor-interacting serine-threonine kinase 4	0.015
PCDH18	protocadherin 18	0.015
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.015
SOS2	son of sevenless homolog 2 (Drosophila)	0.015
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.015	Mouse
FOXD1	forkhead box D1	0.015
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	0.015
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.015
PRKCA	protein kinase C, alpha	0.015
SETDB1	SET domain, bifurcated 1	0.015
DPYSL3	dihydropyrimidinase-like 3	0.015
INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	0.015
RHOB	ras homolog gene family, member B	0.015
ELK1	ELK1, member of ETS oncogene family	0.015
TSPYL5	TSPY-like 5	0.015
ACPP	acid phosphatase, prostate	0.015
PCDH10	protocadherin 10	0.015
GLI3	GLI family zinc finger 3	0.015
RAB23	RAB23, member RAS oncogene family	0.015
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.015
NOV	nephroblastoma overexpressed gene	0.015
SULF2	sulfatase 2	0.015
CD82	CD82 molecule	0.015
TUSC3	tumor suppressor candidate 3	0.015
GPC3	glypican 3	0.015
CDX2	caudal type homeobox 2	0.015
LEF1	lymphoid enhancer-binding factor 1	0.015
FLRT3	fibronectin leucine rich transmembrane protein 3	0.015
CD81	CD81 molecule	0.015
KIF5B	kinesin family member 5B	0.015
ARHGAP15	Rho GTPase activating protein 15	0.015
TMEM131	transmembrane protein 131	0.015
ZCCHC14	zinc finger, CCHC domain containing 14	0.015
TPST1	tyrosylprotein sulfotransferase 1	0.015
TRIO	triple functional domain (PTPRF interacting)	0.015
SOCS5	suppressor of cytokine signaling 5	0.015
C8orf84	chromosome 8 open reading frame 84	0.015
SH3GL2	SH3-domain GRB2-like 2	0.015
ZNF521	zinc finger protein 521	0.015
RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	0.015
TMED2	transmembrane emp24 domain trafficking protein 2	0.015
CLCN5	chloride channel 5	0.015
PLP1	proteolipid protein 1	0.015
RALGDS	ral guanine nucleotide dissociation stimulator	0.015
ZCCHC24	zinc finger, CCHC domain containing 24	0.015
MEN1	multiple endocrine neoplasia I	0.015
TSPAN5	tetraspanin 5	0.015
NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)	0.015
NFE2L3	nuclear factor (erythroid-derived 2)-like 3	0.015
LPAR1	lysophosphatidic acid receptor 1	0.015
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.015
CSRP2	cysteine and glycine-rich protein 2	0.015	Fly
B4GALT6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	0.015
AEBP1	AE binding protein 1	0.015
PRR12	proline rich 12	0.015
CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	0.015
LRRN1	leucine rich repeat neuronal 1	0.015
ACVR2A	activin A receptor, type IIA	0.015
JAG2	jagged 2	0.015
SMOC2	SPARC related modular calcium binding 2	0.015
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.015
NOTCH2	notch 2	0.015
LAMP2	lysosomal-associated membrane protein 2	0.015
GORASP1	golgi reassembly stacking protein 1, 65kDa	0.015
GLI2	GLI family zinc finger 2	0.015
FRZB	frizzled-related protein	0.015
DIXDC1	DIX domain containing 1	0.015
FLI1	Friend leukemia virus integration 1	0.015
C1orf198	chromosome 1 open reading frame 198	0.015
BRPF3	bromodomain and PHD finger containing, 3	0.015
FAM57A	family with sequence similarity 57, member A	0.015
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	0.015
TGFB1	transforming growth factor, beta 1	0.015
CTSL2	cathepsin L2	0.015
CREG1	cellular repressor of E1A-stimulated genes 1	0.015
TMEM22	transmembrane protein 22	0.015
MYOF	myoferlin	0.015
ARHGAP17	Rho GTPase activating protein 17	0.015
NPIP	nuclear pore complex interacting protein	0.015
TMEM44	transmembrane protein 44	0.015
KANK2	KN motif and ankyrin repeat domains 2	0.015
PNMAL1	PNMA-like 1	0.015
GREB1	growth regulation by estrogen in breast cancer 1	0.015
FBLN1	fibulin 1	0.015
PDPR	pyruvate dehydrogenase phosphatase regulatory subunit	0.015
LAMA3	laminin, alpha 3	0.015
DSC3	desmocollin 3	0.015
FAM83D	family with sequence similarity 83, member D	0.015
KIAA1549	KIAA1549	0.015
ABR	active BCR-related gene	0.015
ZBTB11	zinc finger and BTB domain containing 11	0.015
CASKIN2	CASK interacting protein 2	0.015
EHMT1	euchromatic histone-lysine N-methyltransferase 1	0.015
CYTH2	cytohesin 2	0.015
OAZ1	ornithine decarboxylase antizyme 1	0.015
TBX1	T-box 1	0.015
ITPKB	inositol-trisphosphate 3-kinase B	0.015
ZNF74	zinc finger protein 74	0.015
MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	0.015
ZNF496	zinc finger protein 496	0.015
ZNF250	zinc finger protein 250	0.015
BTRC	beta-transducin repeat containing	0.015
PHKA1	phosphorylase kinase, alpha 1 (muscle)	0.015
CPNE1	copine I	0.015
CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	0.015
SCRN1	secernin 1	0.015