IMP: Integrative Multi-species Prediction

Homo sapiens

27 genes annotated in human

Multi-species View

regulation of sister chromatid segregation

GO:0033045

Any process that modulates the frequency, rate or extent of sister chromatid segregation.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of sister chromatid segregation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of sister chromatid segregation" (in gray)

Name	Description	Probability	Func Analog Organism
CDC27	cell division cycle 27 homolog (S. cerevisiae)	1.000
CDC20	cell division cycle 20 homolog (S. cerevisiae)	1.000	Yeast Worm Fly
ANAPC4	anaphase promoting complex subunit 4	1.000
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	1.000	Mouse Fly
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.990	Fly
ANAPC1	anaphase promoting complex subunit 1	0.987	Worm
ANAPC7	anaphase promoting complex subunit 7	0.982
ANAPC5	anaphase promoting complex subunit 5	0.964
CDK2	cyclin-dependent kinase 2	0.961
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.956
RB1	retinoblastoma 1	0.930
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.912
CCNB1	cyclin B1	0.889
CCNA2	cyclin A2	0.819
MDC1	mediator of DNA-damage checkpoint 1	0.646
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.574
ANAPC11	anaphase promoting complex subunit 11	0.516
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.445
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.376
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.331	Worm Fly
FBXO5	F-box protein 5	0.308
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.286
NBN	nibrin	0.236
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.228
CUL2	cullin 2	0.207	Worm
VHL	von Hippel-Lindau tumor suppressor	0.204
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.192	Fly
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.186
PTTG1	pituitary tumor-transforming 1	0.166
SKP2	S-phase kinase-associated protein 2 (p45)	0.155
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.130
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.116	Worm
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.110
ZW10	ZW10, kinetochore associated, homolog (Drosophila)	0.104
RBL1	retinoblastoma-like 1 (p107)	0.100	Human
POMP	proteasome maturation protein	0.100
CCNB2	cyclin B2	0.100
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.099
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.098
BRCA1	breast cancer 1, early onset	0.098
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.096
CDC7	cell division cycle 7 homolog (S. cerevisiae)	0.083
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.082
PTEN	phosphatase and tensin homolog	0.081
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.079
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.076
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.075
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.070
CEP55	centrosomal protein 55kDa	0.066
CBX5	chromobox homolog 5	0.064
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.063
CD44	CD44 molecule (Indian blood group)	0.063
SKA3	spindle and kinetochore associated complex subunit 3	0.061
RBBP8	retinoblastoma binding protein 8	0.060
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.060
BRCA2	breast cancer 2, early onset	0.059
C19orf39	chromosome 19 open reading frame 39	0.059
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.058
HERC2	hect domain and RLD 2	0.055
TP53BP1	tumor protein p53 binding protein 1	0.053
AXIN2	axin 2	0.050
CASC5	cancer susceptibility candidate 5	0.049
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.048
STAG1	stromal antigen 1	0.048
TBC1D10A	TBC1 domain family, member 10A	0.047
KPNB1	karyopherin (importin) beta 1	0.047
SKA1	spindle and kinetochore associated complex subunit 1	0.047
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	0.046
SMC3	structural maintenance of chromosomes 3	0.046
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.045
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.044
CDKN3	cyclin-dependent kinase inhibitor 3	0.043
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.042
TTK	TTK protein kinase	0.041	Yeast
ATMIN	ATM interactor	0.041
ZWINT	ZW10 interactor	0.040
ZNF367	zinc finger protein 367	0.039
AURKB	aurora kinase B	0.037
SKA2	spindle and kinetochore associated complex subunit 2	0.037
RBL2	retinoblastoma-like 2 (p130)	0.037	Human
NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.036
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.035
LRR1	leucine rich repeat protein 1	0.035
SMC6	structural maintenance of chromosomes 6	0.034
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.034
FXR2	fragile X mental retardation, autosomal homolog 2	0.033
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.032
GSK3B	glycogen synthase kinase 3 beta	0.032	Fly
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.032
CUL1	cullin 1	0.032
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.032
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.032
PLK4	polo-like kinase 4	0.032
PAXIP1	PAX interacting (with transcription-activation domain) protein 1	0.031
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.031
SPC24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.029
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.029
ANAPC16	anaphase promoting complex subunit 16	0.029
E2F1	E2F transcription factor 1	0.029
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.028
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.028
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.028
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.028
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.028	Worm
ERCC3	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	0.027
SIRT2	sirtuin 2	0.026
TRIP13	thyroid hormone receptor interactor 13	0.026
SGOL1	shugoshin-like 1 (S. pombe)	0.026
KIF18A	kinesin family member 18A	0.026
MAK	male germ cell-associated kinase	0.025
RIF1	RAP1 interacting factor homolog (yeast)	0.025
KDM4A	lysine (K)-specific demethylase 4A	0.025
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.024
COMMD1	copper metabolism (Murr1) domain containing 1	0.023
PLK1	polo-like kinase 1	0.023
ANAPC13	anaphase promoting complex subunit 13	0.023
CLSPN	claspin	0.023
CUL5	cullin 5	0.022
GPSM2	G-protein signaling modulator 2	0.022
AXIN1	axin 1	0.022
PPME1	protein phosphatase methylesterase 1	0.022
FANCI	Fanconi anemia, complementation group I	0.022
NCAPG2	non-SMC condensin II complex, subunit G2	0.021
DCLRE1C	DNA cross-link repair 1C	0.021
SMC4	structural maintenance of chromosomes 4	0.021
USP9X	ubiquitin specific peptidase 9, X-linked	0.021
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.021
CENPE	centromere protein E, 312kDa	0.021
KIF2C	kinesin family member 2C	0.020
POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	0.020
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.020
MAD2L1BP	MAD2L1 binding protein	0.019
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.019
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.019
KIF11	kinesin family member 11	0.019
TFDP1	transcription factor Dp-1	0.019
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.019
ORC2	origin recognition complex, subunit 2	0.019
RAD51C	RAD51 homolog C (S. cerevisiae)	0.019
E2F5	E2F transcription factor 5, p130-binding	0.019
PRC1	protein regulator of cytokinesis 1	0.018
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.018
ORC3	origin recognition complex, subunit 3	0.018
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.018
MIS18BP1	MIS18 binding protein 1	0.018
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.018
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.018
HIST1H2BH	histone cluster 1, H2bh	0.018
ATAD2	ATPase family, AAA domain containing 2	0.018
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.018
HIST1H4A	histone cluster 1, H4a	0.018
RAD51L1	RAD51-like 1 (S. cerevisiae)	0.018
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.018
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.017
E2F4	E2F transcription factor 4, p107/p130-binding	0.017
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.017
TAGLN2	transgelin 2	0.017
CCND1	cyclin D1	0.017
KIF5B	kinesin family member 5B	0.017
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.017
CUL4A	cullin 4A	0.017
HIST2H2BE	histone cluster 2, H2be	0.017
WBP4	WW domain binding protein 4 (formin binding protein 21)	0.016
PXN	paxillin	0.016
PRRC2C	proline-rich coiled-coil 2C	0.016
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.016
SMAD2	SMAD family member 2	0.016
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.016
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.016
HIST1H3D	histone cluster 1, H3d	0.016
IGF1R	insulin-like growth factor 1 receptor	0.016
HIST1H2AC	histone cluster 1, H2ac	0.016
NEK1	NIMA (never in mitosis gene a)-related kinase 1	0.016
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.016
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.016
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.016
SCAF11	SR-related CTD-associated factor 11	0.016
ARIH2	ariadne homolog 2 (Drosophila)	0.015
USP44	ubiquitin specific peptidase 44	0.015
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.015
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.015
TOP3A	topoisomerase (DNA) III alpha	0.015
CENPF	centromere protein F, 350/400kDa (mitosin)	0.015
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.015
MYH9	myosin, heavy chain 9, non-muscle	0.015
RFWD2	ring finger and WD repeat domain 2	0.015
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.015
USP49	ubiquitin specific peptidase 49	0.015	Human
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.014
RAD21	RAD21 homolog (S. pombe)	0.014
PIM1	pim-1 oncogene	0.014
CDT1	chromatin licensing and DNA replication factor 1	0.014
FOXM1	forkhead box M1	0.014
SGOL2	shugoshin-like 2 (S. pombe)	0.014	Mouse
SERTAD4	SERTA domain containing 4	0.014
HIST1H1E	histone cluster 1, H1e	0.014
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.014
HIST1H1B	histone cluster 1, H1b	0.013
RAD51L3	RAD51-like 3 (S. cerevisiae)	0.013
CDC45	cell division cycle 45 homolog (S. cerevisiae)	0.013
HIST1H2BD	histone cluster 1, H2bd	0.013
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.013
BLM	Bloom syndrome, RecQ helicase-like	0.013
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.013
KIF14	kinesin family member 14	0.013
ADAM17	ADAM metallopeptidase domain 17	0.013
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.013
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.013
DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	0.013
HIST1H4D	histone cluster 1, H4d	0.012
ECT2	epithelial cell transforming sequence 2 oncogene	0.012
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.012
HIST1H3G	histone cluster 1, H3g	0.012
KIAA1279	KIAA1279	0.012
STIL	SCL/TAL1 interrupting locus	0.012
L3MBTL1	l(3)mbt-like 1 (Drosophila)	0.012
NRD1	nardilysin (N-arginine dibasic convertase)	0.012
TPP2	tripeptidyl peptidase II	0.012
MPHOSPH9	M-phase phosphoprotein 9	0.012
MAPK1	mitogen-activated protein kinase 1	0.012
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.012
APC	adenomatous polyposis coli	0.012
C18orf21	chromosome 18 open reading frame 21	0.011
CCDC99	coiled-coil domain containing 99	0.011
EML4	echinoderm microtubule associated protein like 4	0.011
KDM5C	lysine (K)-specific demethylase 5C	0.011
MYO1C	myosin IC	0.011
INCENP	inner centromere protein antigens 135/155kDa	0.011
CUL3	cullin 3	0.011
TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	0.011
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.011
UBASH3B	ubiquitin associated and SH3 domain containing B	0.011
MASTL	microtubule associated serine/threonine kinase-like	0.011
CEP152	centrosomal protein 152kDa	0.011
BRPF1	bromodomain and PHD finger containing, 1	0.011
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.011
HIST1H1C	histone cluster 1, H1c	0.011
CKS2	CDC28 protein kinase regulatory subunit 2	0.011
HIST1H2AM	histone cluster 1, H2am	0.011
ANLN	anillin, actin binding protein	0.011
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.011
PPP4C	protein phosphatase 4, catalytic subunit	0.011
GTSE1	G-2 and S-phase expressed 1	0.011
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.010
EIF4E	eukaryotic translation initiation factor 4E	0.010
HIST1H2AE	histone cluster 1, H2ae	0.010
H2AFX	H2A histone family, member X	0.010
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.010
DCLRE1B	DNA cross-link repair 1B	0.010
PRAME	preferentially expressed antigen in melanoma	0.010
CEP110	centrosomal protein 110kDa	0.010
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.010
PHF20	PHD finger protein 20	0.010
ZSWIM7	zinc finger, SWIM-type containing 7	0.010
EML2	echinoderm microtubule associated protein like 2	0.010
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.010