IMP: Integrative Multi-species Prediction

Homo sapiens

22 genes annotated in human

Multi-species View

establishment of protein localization to mitochondrion

GO:0072655

The directed movement of a protein to a specific location in the mitochondrion.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment of protein localization to mitochondrion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "establishment of protein localization to mitochondrion" (in gray)

Name	Description	Probability	Func Analog Organism
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.998
HSPA1B	heat shock 70kDa protein 1B	0.998	Yeast
TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)	0.963	Yeast
BCL2	B-cell CLL/lymphoma 2	0.932
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.924
MARCH5	membrane-associated ring finger (C3HC4) 5	0.913
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.882	Yeast
BAX	BCL2-associated X protein	0.866	Mouse
TIMM10	translocase of inner mitochondrial membrane 10 homolog (yeast)	0.839
PPID	peptidylprolyl isomerase D	0.782
BCL2L1	BCL2-like 1	0.770
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.709	Human
HSPA1A	heat shock 70kDa protein 1A	0.576	Yeast
TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)	0.571	Yeast
BECN1	beclin 1, autophagy related	0.515
HSPA8	heat shock 70kDa protein 8	0.497	Yeast
NUB1	negative regulator of ubiquitin-like proteins 1	0.450
MAP2K4	mitogen-activated protein kinase kinase 4	0.448
BAD	BCL2-associated agonist of cell death	0.446
MAPK8	mitogen-activated protein kinase 8	0.411
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.356
TOMM70A	translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)	0.277
MRPL24	mitochondrial ribosomal protein L24	0.258
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.240
TP53BP2	tumor protein p53 binding protein, 2	0.223
PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)	0.219	Yeast
PINK1	PTEN induced putative kinase 1	0.218
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.215
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.214
STIP1	stress-induced-phosphoprotein 1	0.193
BAK1	BCL2-antagonist/killer 1	0.176
DNM1L	dynamin 1-like	0.161
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.156
RABGGTB	Rab geranylgeranyltransferase, beta subunit	0.148
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.144
MEOX2	mesenchyme homeobox 2	0.140
HUWE1	HECT, UBA and WWE domain containing 1	0.126
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.125
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.123
TCP1	t-complex 1	0.114
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.106
HSPH1	heat shock 105kDa/110kDa protein 1	0.105	Human
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.104
BAG3	BCL2-associated athanogene 3	0.104
TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)	0.098
RNF144B	ring finger protein 144B	0.097
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	0.096
PPP5C	protein phosphatase 5, catalytic subunit	0.095
SKA3	spindle and kinetochore associated complex subunit 3	0.093
BIK	BCL2-interacting killer (apoptosis-inducing)	0.093
TIMM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	0.087	Yeast
SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	0.086
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.085
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.080
MAGEH1	melanoma antigen family H, 1	0.077
KIAA0664	KIAA0664	0.077
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.077
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.076
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.075	Yeast
COQ3	coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	0.069
EIF5	eukaryotic translation initiation factor 5	0.068
CDK7	cyclin-dependent kinase 7	0.067
TOMM20	translocase of outer mitochondrial membrane 20 homolog (yeast)	0.065
MRPS12	mitochondrial ribosomal protein S12	0.063
TMED2	transmembrane emp24 domain trafficking protein 2	0.062
TIMM8A	translocase of inner mitochondrial membrane 8 homolog A (yeast)	0.059	Yeast
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.056
DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.053	Yeast
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.053
ETF1	eukaryotic translation termination factor 1	0.052
TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	0.051
NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	0.048
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.046
CIAPIN1	cytokine induced apoptosis inhibitor 1	0.046
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.045
NMD3	NMD3 homolog (S. cerevisiae)	0.045
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.045
MRPL35	mitochondrial ribosomal protein L35	0.044
NUDC	nuclear distribution gene C homolog (A. nidulans)	0.043
SS18	synovial sarcoma translocation, chromosome 18	0.043
AMBRA1	autophagy/beclin-1 regulator 1	0.043
XPO7	exportin 7	0.042
BZW1	basic leucine zipper and W2 domains 1	0.040
TMX2	thioredoxin-related transmembrane protein 2	0.040
NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit	0.040
SERTAD4	SERTA domain containing 4	0.038
GHITM	growth hormone inducible transmembrane protein	0.036
CANX	calnexin	0.035
BCAP31	B-cell receptor-associated protein 31	0.035
SLC25A46	solute carrier family 25, member 46	0.035
SUGT1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	0.034
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.034
PEX19	peroxisomal biogenesis factor 19	0.033
KIF5B	kinesin family member 5B	0.033
YAF2	YY1 associated factor 2	0.033
TIMM23	translocase of inner mitochondrial membrane 23 homolog (yeast) and translocase of inner mitochondrial membrane 23 homolog (yeast)	0.033	Yeast
TBK1	TANK-binding kinase 1	0.031
CCNG1	cyclin G1	0.030
DCTN6	dynactin 6	0.030
EPRS	glutamyl-prolyl-tRNA synthetase	0.030
RNMTL1	RNA methyltransferase like 1	0.030
BAG2	BCL2-associated athanogene 2	0.028
METTL1	methyltransferase like 1	0.028
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.027
RSL24D1	ribosomal L24 domain containing 1	0.027
KIAA1279	KIAA1279	0.026
HCCS	holocytochrome c synthase	0.026
DNAJC19	DnaJ (Hsp40) homolog, subfamily C, member 19	0.026	Yeast
AZIN1	antizyme inhibitor 1	0.025
NDUFB11	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa	0.025
NOP16	NOP16 nucleolar protein homolog (yeast)	0.023
THAP4	THAP domain containing 4	0.023
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.022
JUN	jun proto-oncogene	0.022
TUSC2	tumor suppressor candidate 2	0.022
CHCHD8	coiled-coil-helix-coiled-coil-helix domain containing 8	0.021
TXN2	thioredoxin 2	0.021
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.021
MRPS7	mitochondrial ribosomal protein S7	0.021
BAG1	BCL2-associated athanogene	0.021
NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	0.021
TIMM50	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	0.021
RAB5B	RAB5B, member RAS oncogene family	0.020
MCAT	malonyl CoA:ACP acyltransferase (mitochondrial)	0.020
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.020
VDAC1	voltage-dependent anion channel 1	0.020
ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	0.020
USE1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	0.020
PRDX5	peroxiredoxin 5	0.020
RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	0.020
TOMM7	translocase of outer mitochondrial membrane 7 homolog (yeast)	0.020
SUPV3L1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.020
EIF2A	eukaryotic translation initiation factor 2A, 65kDa	0.019
FKBP4	FK506 binding protein 4, 59kDa	0.019
TUBA1A	tubulin, alpha 1a	0.019
RAB4A	RAB4A, member RAS oncogene family	0.019
NOP14	NOP14 nucleolar protein homolog (yeast)	0.019
TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.019
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.019
CDK9	cyclin-dependent kinase 9	0.019
USP30	ubiquitin specific peptidase 30	0.018
SIRT3	sirtuin 3	0.018
STRAP	serine/threonine kinase receptor associated protein	0.018
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.018
FIS1	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	0.018
CNBP	CCHC-type zinc finger, nucleic acid binding protein	0.018
ERAL1	Era G-protein-like 1 (E. coli)	0.018
LANCL1	LanC lantibiotic synthetase component C-like 1 (bacterial)	0.017
PGRMC1	progesterone receptor membrane component 1	0.017
MAP2K6	mitogen-activated protein kinase kinase 6	0.017
CCDC56	coiled-coil domain containing 56	0.017
FYTTD1	forty-two-three domain containing 1	0.017
TRIP12	thyroid hormone receptor interactor 12	0.017
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.017
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.017
C12orf62	chromosome 12 open reading frame 62	0.017
CCDC117	coiled-coil domain containing 117	0.016
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.016
NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4	0.016
SLC5A6	solute carrier family 5 (sodium-dependent vitamin transporter), member 6	0.016
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.016
GFM1	G elongation factor, mitochondrial 1	0.016
CDV3	CDV3 homolog (mouse)	0.016
NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	0.016
EI24	etoposide induced 2.4 mRNA	0.016
SPAG7	sperm associated antigen 7	0.016
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.015
GRSF1	G-rich RNA sequence binding factor 1	0.015
ARMC6	armadillo repeat containing 6	0.015
IMP4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)	0.015
CYCS	cytochrome c, somatic	0.015
ROMO1	reactive oxygen species modulator 1	0.015
FAM175B	family with sequence similarity 175, member B	0.015
RNF6	ring finger protein (C3H2C3 type) 6	0.015
DERL1	Der1-like domain family, member 1	0.015
HIGD2A	HIG1 hypoxia inducible domain family, member 2A	0.014
PMVK	phosphomevalonate kinase	0.014
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.014
CCNH	cyclin H	0.014
BCL2A1	BCL2-related protein A1	0.014
NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	0.014
TMEM186	transmembrane protein 186	0.014
GFPT1	glutamine--fructose-6-phosphate transaminase 1	0.014
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.014
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.014
PPIF	peptidylprolyl isomerase F	0.014
EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	0.014
EIF3J	eukaryotic translation initiation factor 3, subunit J	0.014
MRPL46	mitochondrial ribosomal protein L46	0.014
PTP4A1	protein tyrosine phosphatase type IVA, member 1	0.013
CCDC86	coiled-coil domain containing 86	0.013
PDHX	pyruvate dehydrogenase complex, component X	0.013
HARS	histidyl-tRNA synthetase	0.013
GBAS	glioblastoma amplified sequence	0.013
DHODH	dihydroorotate dehydrogenase	0.013
LRP6	low density lipoprotein receptor-related protein 6	0.013
KLHDC2	kelch domain containing 2	0.013
DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	0.013	Yeast
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.013
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.013
CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	0.013
NCKAP1	NCK-associated protein 1	0.013
MAPK1	mitogen-activated protein kinase 1	0.013
MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	0.013
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.012
PTS	6-pyruvoyltetrahydropterin synthase	0.012
CUL2	cullin 2	0.012
SLC39A6	solute carrier family 39 (zinc transporter), member 6	0.012
COG5	component of oligomeric golgi complex 5	0.012
GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1	0.012
SPNS1	spinster homolog 1 (Drosophila)	0.012
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.012
PDCD11	programmed cell death 11	0.012
LMAN1	lectin, mannose-binding, 1	0.012
DDT	D-dopachrome tautomerase	0.012
MAP1B	microtubule-associated protein 1B	0.012
NAF1	nuclear assembly factor 1 homolog (S. cerevisiae)	0.012
AICDA	activation-induced cytidine deaminase	0.012
DCTN3	dynactin 3 (p22)	0.012
BRP44	brain protein 44	0.012
DLAT	dihydrolipoamide S-acetyltransferase	0.012
ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	0.012
NPM3	nucleophosmin/nucleoplasmin 3	0.012
PPHLN1	periphilin 1	0.011
IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	0.011
RTCD1	RNA terminal phosphate cyclase domain 1	0.011
NOL6	nucleolar protein family 6 (RNA-associated)	0.011
SELT	selenoprotein T	0.011
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.011
NSFL1C	NSFL1 (p97) cofactor (p47)	0.011
NADSYN1	NAD synthetase 1	0.011
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.011
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.011
FASTKD5	FAST kinase domains 5	0.011
SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)	0.011
RNR2	l-rRNA	0.011
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.011
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.011
TSPYL4	TSPY-like 4	0.011
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.011
TSFM	Ts translation elongation factor, mitochondrial	0.011
C20orf30	chromosome 20 open reading frame 30	0.011
MRPL28	mitochondrial ribosomal protein L28	0.011
BCL2L2	BCL2-like 2	0.011
CLINT1	clathrin interactor 1	0.011
C20orf7	chromosome 20 open reading frame 7	0.011
GFM2	G elongation factor, mitochondrial 2	0.011
PNO1	partner of NOB1 homolog (S. cerevisiae)	0.011
PLEKHM1	pleckstrin homology domain containing, family M (with RUN domain) member 1	0.011
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.011
RAB5A	RAB5A, member RAS oncogene family	0.011
ATF2	activating transcription factor 2	0.011
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.011
ZFAND1	zinc finger, AN1-type domain 1	0.011
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.010
SENP2	SUMO1/sentrin/SMT3 specific peptidase 2	0.010
IER5	immediate early response 5	0.010
EXOC5	exocyst complex component 5	0.010
BCL2L12	BCL2-like 12 (proline rich)	0.010
RWDD4	RWD domain containing 4	0.010
MRPL32	mitochondrial ribosomal protein L32	0.010
COMMD1	copper metabolism (Murr1) domain containing 1	0.010
GTF2B	general transcription factor IIB	0.010
EIF5A	eukaryotic translation initiation factor 5A	0.010
FXC1	fracture callus 1 homolog (rat)	0.010
DPH2	DPH2 homolog (S. cerevisiae)	0.010