IMP: Integrative Multi-species Prediction

Homo sapiens

22 genes annotated in human

Multi-species View

cellular glucan metabolic process

GO:0006073

The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular glucan metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular glucan metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	1.000
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	1.000	Yeast
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.999	Yeast
IRS1	insulin receptor substrate 1	0.963
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.927
IRS2	insulin receptor substrate 2	0.870
GRB10	growth factor receptor-bound protein 10	0.868	Rat
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.840
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.751
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.722	Yeast
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.640	Human
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.585
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.567	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.547
IGF1R	insulin-like growth factor 1 receptor	0.509	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.475
CREBBP	CREB binding protein	0.452
AR	androgen receptor	0.440
PSEN1	presenilin 1	0.379
RXRA	retinoid X receptor, alpha	0.374
KAT2B	K(lysine) acetyltransferase 2B	0.372
GYS1	glycogen synthase 1 (muscle)	0.362
GSK3B	glycogen synthase kinase 3 beta	0.317
VCP	valosin containing protein	0.311
FHL2	four and a half LIM domains 2	0.309
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.267
NCOA1	nuclear receptor coactivator 1	0.254
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.249	Rat
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.235
DCAF7	DDB1 and CUL4 associated factor 7	0.220
NCF1	neutrophil cytosolic factor 1	0.213
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.182
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.176
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.165
BTRC	beta-transducin repeat containing	0.157
NCOA6	nuclear receptor coactivator 6	0.150
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.148
FBXW11	F-box and WD repeat domain containing 11	0.144
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.138
FOXO3	forkhead box O3	0.136	Fly
CREB1	cAMP responsive element binding protein 1	0.115
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.115	Human
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.106	Worm
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.105
NCOA2	nuclear receptor coactivator 2	0.100
RAB6A	RAB6A, member RAS oncogene family	0.099
HIPK2	homeodomain interacting protein kinase 2	0.097
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.094	Worm
JAK2	Janus kinase 2	0.094
SFN	stratifin	0.090	Yeast
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.089
RARA	retinoic acid receptor, alpha	0.088
EGFR	epidermal growth factor receptor	0.085
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.084
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.082
FOXO1	forkhead box O1	0.079	Fly
PICK1	protein interacting with PRKCA 1	0.078
PGK1	phosphoglycerate kinase 1	0.075
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.074
PRKCZ	protein kinase C, zeta	0.072	Human
CDCP1	CUB domain containing protein 1	0.071
OSBP	oxysterol binding protein	0.070
RUNX1	runt-related transcription factor 1	0.069
STAT5B	signal transducer and activator of transcription 5B	0.068
HR	hairless homolog (mouse)	0.068
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.068
HIC1	hypermethylated in cancer 1	0.067
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.065
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.064	Yeast
PRKCSH	protein kinase C substrate 80K-H	0.060
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.059
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.057
GYG1	glycogenin 1	0.057	Yeast
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.056
SRP9	signal recognition particle 9kDa	0.056
RAB8A	RAB8A, member RAS oncogene family	0.054
IL6R	interleukin 6 receptor	0.051
PRKCB	protein kinase C, beta	0.051
MAPT	microtubule-associated protein tau	0.049
SIRT1	sirtuin 1	0.049
GYG2	glycogenin 2	0.047	Yeast
IGF2R	insulin-like growth factor 2 receptor	0.045
LZTS2	leucine zipper, putative tumor suppressor 2	0.044
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.044
FAF1	Fas (TNFRSF6) associated factor 1	0.043
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.042	Rat
MED25	mediator complex subunit 25	0.042
CSNK2B	casein kinase 2, beta polypeptide	0.041
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.041
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.041
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.040
SMAD2	SMAD family member 2	0.039
SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.038
GCKR	glucokinase (hexokinase 4) regulator	0.038
SH2B1	SH2B adaptor protein 1	0.038
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.035
SRSF5	serine/arginine-rich splicing factor 5	0.035
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.035
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.033
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.033
UBXN2A	UBX domain protein 2A	0.033
AXIN1	axin 1	0.033
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.032
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.031
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.030
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.028
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.027
CCND3	cyclin D3	0.026
EPOR	erythropoietin receptor	0.024
ACACA	acetyl-CoA carboxylase alpha	0.024
HDAC4	histone deacetylase 4	0.024
SESN2	sestrin 2	0.024
PDPK1	3-phosphoinositide dependent protein kinase-1	0.023
GLTPD1	glycolipid transfer protein domain containing 1	0.023
GHR	growth hormone receptor	0.022
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.022
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.022
APC	adenomatous polyposis coli	0.022
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.022
YAP1	Yes-associated protein 1	0.022
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.021	Yeast
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.021
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.021
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.020
FKBP4	FK506 binding protein 4, 59kDa	0.020
PPID	peptidylprolyl isomerase D	0.020
HDAC3	histone deacetylase 3	0.020
CSK	c-src tyrosine kinase	0.020
BCKDK	branched chain ketoacid dehydrogenase kinase	0.020
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.020
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.020
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.019
GYS2	glycogen synthase 2 (liver)	0.019
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.019
LRRK2	leucine-rich repeat kinase 2	0.019
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.018
FRS2	fibroblast growth factor receptor substrate 2	0.018
ATXN3	ataxin 3	0.018
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.018
INPPL1	inositol polyphosphate phosphatase-like 1	0.018
HMOX2	heme oxygenase (decycling) 2	0.018
CUX1	cut-like homeobox 1	0.018
LAT	linker for activation of T cells	0.018
TNIK	TRAF2 and NCK interacting kinase	0.017
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.016
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.016
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.016
KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.016
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.016
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.016
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.016
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.016
FYN	FYN oncogene related to SRC, FGR, YES	0.016
CLN3	ceroid-lipofuscinosis, neuronal 3	0.015
STAT2	signal transducer and activator of transcription 2, 113kDa	0.015
GRB14	growth factor receptor-bound protein 14	0.015
TRIM9	tripartite motif containing 9	0.015
CALR	calreticulin	0.015
CCND1	cyclin D1	0.015
NUCB1	nucleobindin 1	0.014
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.014
RPN2	ribophorin II	0.014
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.014
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.014
CNTF	ciliary neurotrophic factor	0.014
LDLR	low density lipoprotein receptor	0.014
NCOA3	nuclear receptor coactivator 3	0.014
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.014
SMAD7	SMAD family member 7	0.013
RPTOR	regulatory associated protein of MTOR, complex 1	0.013
PPP5C	protein phosphatase 5, catalytic subunit	0.013
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.013
CCL14	chemokine (C-C motif) ligand 14	0.013
GAB1	GRB2-associated binding protein 1	0.013
ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	0.013
CAV1	caveolin 1, caveolae protein, 22kDa	0.013
CYBA	cytochrome b-245, alpha polypeptide	0.013
RAB5A	RAB5A, member RAS oncogene family	0.013
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.013
HYOU1	hypoxia up-regulated 1	0.013
EP300	E1A binding protein p300	0.013
IGFBP3	insulin-like growth factor binding protein 3	0.013
ALDOA	aldolase A, fructose-bisphosphate	0.012
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.012
COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.012
GPI	glucose-6-phosphate isomerase	0.012
SLC35A3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	0.012
AXIN2	axin 2	0.012
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.012
PILRA	paired immunoglobin-like type 2 receptor alpha	0.012
PHKB	phosphorylase kinase, beta	0.011
TEF	thyrotrophic embryonic factor	0.011
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.011
CCDC115	coiled-coil domain containing 115	0.011
CTNNBIP1	catenin, beta interacting protein 1	0.011
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.011
NMT2	N-myristoyltransferase 2	0.011
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.011
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.011
ISOC1	isochorismatase domain containing 1	0.011
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.011
DCTN1	dynactin 1	0.011
PKM2	pyruvate kinase, muscle	0.011
MARK3	MAP/microtubule affinity-regulating kinase 3	0.010
S100A2	S100 calcium binding protein A2	0.010
TF	transferrin	0.010
TCF4	transcription factor 4	0.010
CLTC	clathrin, heavy chain (Hc)	0.010
STX16	syntaxin 16	0.010
PIM1	pim-1 oncogene	0.010	Yeast
AQP7	aquaporin 7	0.010
PRKCA	protein kinase C, alpha	0.010
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.010