IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

organ formation

The process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

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Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "organ formation" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000	Mouse
NOTCH1	notch 1	1.000	Rat Fly
JAG1	jagged 1	1.000
FGFR1	fibroblast growth factor receptor 1	1.000	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.999	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.999
CSNK1E	casein kinase 1, epsilon	0.998
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.997	Fly
FHL2	four and a half LIM domains 2	0.992
SOX10	SRY (sex determining region Y)-box 10	0.992
FOXD3	forkhead box D3	0.985
FGF10	fibroblast growth factor 10	0.984
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.979	Fly
SUFU	suppressor of fused homolog (Drosophila)	0.965
SP1	Sp1 transcription factor	0.960
NKX2-1	NK2 homeobox 1	0.957
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.952
TBX5	T-box 5	0.904	Mouse
FGF8	fibroblast growth factor 8 (androgen-induced)	0.900
GATA4	GATA binding protein 4	0.896	Zebrafish
HOXD13	homeobox D13	0.877
EP300	E1A binding protein p300	0.874
MEOX2	mesenchyme homeobox 2	0.853
POU3F2	POU class 3 homeobox 2	0.844
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.844
WT1	Wilms tumor 1	0.841	Mouse
NCOA2	nuclear receptor coactivator 2	0.834
HDAC4	histone deacetylase 4	0.819
NOG	noggin	0.812	Mouse
FGF2	fibroblast growth factor 2 (basic)	0.806	Human Mouse
JAG2	jagged 2	0.784
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.780
TP73	tumor protein p73	0.778
MAML1	mastermind-like 1 (Drosophila)	0.776
TGFB3	transforming growth factor, beta 3	0.774
ITGB4	integrin, beta 4	0.774
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.745
PAX2	paired box 2	0.740	Mouse
PLCG1	phospholipase C, gamma 1	0.732
LHX3	LIM homeobox 3	0.720	Human
NOTCH3	notch 3	0.715	Fly
SIX6	SIX homeobox 6	0.714
SOX2	SRY (sex determining region Y)-box 2	0.700
SMAD1	SMAD family member 1	0.696
FGFR3	fibroblast growth factor receptor 3	0.695
ZNF512B	zinc finger protein 512B	0.691
FGF3	fibroblast growth factor 3	0.685	Human
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.677
LBX1	ladybird homeobox 1	0.669
CABLES1	Cdk5 and Abl enzyme substrate 1	0.668
MYOD1	myogenic differentiation 1	0.629
LMX1A	LIM homeobox transcription factor 1, alpha	0.620	Human
RAX	retina and anterior neural fold homeobox	0.608
OTP	orthopedia homeobox	0.607
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.602
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.578
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.577
HOXD9	homeobox D9	0.562
DLL1	delta-like 1 (Drosophila)	0.555
STK36	serine/threonine kinase 36	0.555
LHX1	LIM homeobox 1	0.553	Human
LRP6	low density lipoprotein receptor-related protein 6	0.544
FSTL1	follistatin-like 1	0.540
CDK11B	cyclin-dependent kinase 11B	0.520
TGFB1	transforming growth factor, beta 1	0.516
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.505
LHX5	LIM homeobox 5	0.503	Human
BMP7	bone morphogenetic protein 7	0.501	Mouse
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.493
FOXA2	forkhead box A2	0.487
HOXA10	homeobox A10	0.485
CTBP1	C-terminal binding protein 1	0.482	Fly
VAX2	ventral anterior homeobox 2	0.479
FGF7	fibroblast growth factor 7	0.473	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.464
FGF4	fibroblast growth factor 4	0.462	Human
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.456
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.451
PHOX2A	paired-like homeobox 2a	0.444
HOXB5	homeobox B5	0.440
SIX2	SIX homeobox 2	0.440
NEUROG3	neurogenin 3	0.440
NCOR2	nuclear receptor corepressor 2	0.438
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.435
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.433
CTNNBIP1	catenin, beta interacting protein 1	0.424
ALX3	ALX homeobox 3	0.421
ATXN1L	ataxin 1-like	0.419
TGIF1	TGFB-induced factor homeobox 1	0.416
CPE	carboxypeptidase E	0.408
TLX2	T-cell leukemia homeobox 2	0.406
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.405
SIM2	single-minded homolog 2 (Drosophila)	0.405
SOX1	SRY (sex determining region Y)-box 1	0.403
ALX4	ALX homeobox 4	0.398
HIC1	hypermethylated in cancer 1	0.393
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.386	Mouse Fly
FOXB1	forkhead box B1	0.386
SOX11	SRY (sex determining region Y)-box 11	0.382
NOVA2	neuro-oncological ventral antigen 2	0.379
NPAS1	neuronal PAS domain protein 1	0.378
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.376	Mouse Fly
LMX1B	LIM homeobox transcription factor 1, beta	0.363	Human
TBX1	T-box 1	0.363
BMP2	bone morphogenetic protein 2	0.356	Human
HES2	hairy and enhancer of split 2 (Drosophila)	0.356	Fly
PDX1	pancreatic and duodenal homeobox 1	0.354
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.353
PAX7	paired box 7	0.350
NKX6-1	NK6 homeobox 1	0.347
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.343
PAX8	paired box 8	0.339	Mouse
HOXD12	homeobox D12	0.339
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.337
HIPK2	homeodomain interacting protein kinase 2	0.333
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.332
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	0.329
WNT7A	wingless-type MMTV integration site family, member 7A	0.318
FOXN4	forkhead box N4	0.314
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.313
BHLHE23	basic helix-loop-helix family, member e23	0.313
HOXD10	homeobox D10	0.304
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.303
COL2A1	collagen, type II, alpha 1	0.299
POU3F3	POU class 3 homeobox 3	0.299
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.298
UTF1	undifferentiated embryonic cell transcription factor 1	0.296
SATB2	SATB homeobox 2	0.293
FHL1	four and a half LIM domains 1	0.291
DHH	desert hedgehog	0.288
DLX4	distal-less homeobox 4	0.285	Fly
FZD1	frizzled homolog 1 (Drosophila)	0.285
PLEC	plectin	0.284
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.282
HOXB9	homeobox B9	0.279
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.279
SFRP5	secreted frizzled-related protein 5	0.277
COL13A1	collagen, type XIII, alpha 1	0.276
IRX4	iroquois homeobox 4	0.273
ARNT	aryl hydrocarbon receptor nuclear translocator	0.272
EPAS1	endothelial PAS domain protein 1	0.267
VSX1	visual system homeobox 1	0.267
KLF4	Kruppel-like factor 4 (gut)	0.266
POU4F2	POU class 4 homeobox 2	0.266
SOX13	SRY (sex determining region Y)-box 13	0.264
FOXE3	forkhead box E3	0.264
HMGA1	high mobility group AT-hook 1	0.256
BMP4	bone morphogenetic protein 4	0.252
CREBBP	CREB binding protein	0.250
HOXB13	homeobox B13	0.250
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.250
PRDM8	PR domain containing 8	0.248
KRT5	keratin 5	0.247
MEF2A	myocyte enhancer factor 2A	0.247
PML	promyelocytic leukemia	0.246
PYY	peptide YY	0.245
DLX2	distal-less homeobox 2	0.244
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.242
NKX3-2	NK3 homeobox 2	0.241	Mouse
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.241
MDFI	MyoD family inhibitor	0.239
TGFB2	transforming growth factor, beta 2	0.236
SOX21	SRY (sex determining region Y)-box 21	0.228
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.227
WNT1	wingless-type MMTV integration site family, member 1	0.226	Fly
CRHR1	corticotropin releasing hormone receptor 1	0.221
PAX1	paired box 1	0.220
NEUROG1	neurogenin 1	0.219
HOXA11	homeobox A11	0.219	Mouse
VSX2	visual system homeobox 2	0.218
WNT3	wingless-type MMTV integration site family, member 3	0.217
MNX1	motor neuron and pancreas homeobox 1	0.217
POU4F1	POU class 4 homeobox 1	0.216
HOXD1	homeobox D1	0.212
CADM4	cell adhesion molecule 4	0.211
POU4F3	POU class 4 homeobox 3	0.211
HDAC9	histone deacetylase 9	0.209
ECEL1	endothelin converting enzyme-like 1	0.209
WDYHV1	WDYHV motif containing 1	0.206
SIX3	SIX homeobox 3	0.206
PAX3	paired box 3	0.203	Mouse
PITX1	paired-like homeodomain 1	0.203
PAX6	paired box 6	0.202
HAND2	heart and neural crest derivatives expressed 2	0.201	Mouse
KLF13	Kruppel-like factor 13	0.201
HOXA13	homeobox A13	0.200
HOXC8	homeobox C8	0.199
TAOK1	TAO kinase 1	0.198
NRIP1	nuclear receptor interacting protein 1	0.197
HAND1	heart and neural crest derivatives expressed 1	0.197
AXIN1	axin 1	0.192
FOXL1	forkhead box L1	0.191
HOXC11	homeobox C11	0.191	Mouse
MSX1	msh homeobox 1	0.191
ESPN	espin	0.189
ZBTB8A	zinc finger and BTB domain containing 8A	0.188
TBX2	T-box 2	0.188
FHL3	four and a half LIM domains 3	0.187
BBS10	Bardet-Biedl syndrome 10	0.183
GSX2	GS homeobox 2	0.182
FOXG1	forkhead box G1	0.179
OLIG2	oligodendrocyte lineage transcription factor 2	0.179
HOXD11	homeobox D11	0.178	Mouse
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.177
FOXO1	forkhead box O1	0.177
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.177
BMPR1A	bone morphogenetic protein receptor, type IA	0.176	Mouse
NKX2-8	NK2 homeobox 8	0.176
HOXC5	homeobox C5	0.176
FOXA1	forkhead box A1	0.175
NKD2	naked cuticle homolog 2 (Drosophila)	0.174
PEX26	peroxisomal biogenesis factor 26	0.174
DMRT1	doublesex and mab-3 related transcription factor 1	0.172
ENG	endoglin	0.171
HMX3	H6 family homeobox 3	0.171
WNT10A	wingless-type MMTV integration site family, member 10A	0.169
SMAD7	SMAD family member 7	0.169
HOXC13	homeobox C13	0.169
CDX2	caudal type homeobox 2	0.167
NCOA6	nuclear receptor coactivator 6	0.167
ONECUT2	one cut homeobox 2	0.166
GBX2	gastrulation brain homeobox 2	0.166
DLL3	delta-like 3 (Drosophila)	0.162
GSC	goosecoid homeobox	0.161
NCOA7	nuclear receptor coactivator 7	0.161
TLX3	T-cell leukemia homeobox 3	0.161
CEP164	centrosomal protein 164kDa	0.158
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.157
INSRR	insulin receptor-related receptor	0.156
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.156
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.155
RAB11FIP3	RAB11 family interacting protein 3 (class II)	0.155	Fly
PITX3	paired-like homeodomain 3	0.153
DRD4	dopamine receptor D4	0.153
HCFC1	host cell factor C1 (VP16-accessory protein)	0.153
WNT6	wingless-type MMTV integration site family, member 6	0.153
EYA1	eyes absent homolog 1 (Drosophila)	0.153
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.150
EYA2	eyes absent homolog 2 (Drosophila)	0.149
HMGA2	high mobility group AT-hook 2	0.149
PGR	progesterone receptor	0.149
TCF4	transcription factor 4	0.148
PDGFC	platelet derived growth factor C	0.147
MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)	0.147
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.146
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.144
OTX2	orthodenticle homeobox 2	0.143
GDNF	glial cell derived neurotrophic factor	0.143	Mouse
FOXD2	forkhead box D2	0.142
GATA5	GATA binding protein 5	0.142
HOXB6	homeobox B6	0.141
MESP1	mesoderm posterior 1 homolog (mouse)	0.141	Mouse
MCC	mutated in colorectal cancers	0.138
THAP11	THAP domain containing 11	0.138
IL11	interleukin 11	0.137
EVX1	even-skipped homeobox 1	0.135
BARHL1	BarH-like homeobox 1	0.134	Fly
FZD8	frizzled homolog 8 (Drosophila)	0.133
HOXA4	homeobox A4	0.133
FOXF2	forkhead box F2	0.133
SOX18	SRY (sex determining region Y)-box 18	0.131
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.130
DIO3	deiodinase, iodothyronine, type III	0.129
HOXC10	homeobox C10	0.129
GDF7	growth differentiation factor 7	0.127
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.126
MYO10	myosin X	0.126
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.125
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.125
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.125
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.124
NKX6-2	NK6 homeobox 2	0.124
BNC1	basonuclin 1	0.124
NXPH4	neurexophilin 4	0.123
CALCA	calcitonin-related polypeptide alpha	0.122
CTPS2	CTP synthase II	0.122
AMN	amnionless homolog (mouse)	0.121
KLHL35	kelch-like 35 (Drosophila)	0.121
PTF1A	pancreas specific transcription factor, 1a	0.121
NEUROG2	neurogenin 2	0.121
GPR6	G protein-coupled receptor 6	0.121
ZEB1	zinc finger E-box binding homeobox 1	0.120
FRS2	fibroblast growth factor receptor substrate 2	0.118	Mouse
PRDM12	PR domain containing 12	0.118
HNF1B	HNF1 homeobox B	0.117
SCARF2	scavenger receptor class F, member 2	0.117
C1orf31	chromosome 1 open reading frame 31	0.117
HOXC12	homeobox C12	0.116
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.116
RIMS4	regulating synaptic membrane exocytosis 4	0.115
C1QL1	complement component 1, q subcomponent-like 1	0.115
PAX5	paired box 5	0.115
FEV	FEV (ETS oncogene family)	0.115
SSTR5	somatostatin receptor 5	0.114
HTR6	5-hydroxytryptamine (serotonin) receptor 6	0.113
HOXB3	homeobox B3	0.113
SMAD6	SMAD family member 6	0.113
GSC2	goosecoid homeobox 2	0.112
EMX1	empty spiracles homeobox 1	0.111
T	T, brachyury homolog (mouse)	0.111
PDIA3	protein disulfide isomerase family A, member 3	0.110
LRRK2	leucine-rich repeat kinase 2	0.110
GCM2	glial cells missing homolog 2 (Drosophila)	0.110
ZNF331	zinc finger protein 331	0.109
HOXC4	homeobox C4	0.109
GJD2	gap junction protein, delta 2, 36kDa	0.109
PITX2	paired-like homeodomain 2	0.108
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.108
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.108
CD9	CD9 molecule	0.108
KAT2B	K(lysine) acetyltransferase 2B	0.106
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.106
HOXB7	homeobox B7	0.104
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.104
HOXD3	homeobox D3	0.104
FOXF1	forkhead box F1	0.103
POU3F1	POU class 3 homeobox 1	0.103
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.103
EN2	engrailed homeobox 2	0.102
GLI3	GLI family zinc finger 3	0.102	Mouse Fly
CTBP2	C-terminal binding protein 2	0.101	Fly
YAP1	Yes-associated protein 1	0.101
DSG2	desmoglein 2	0.101
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.101
HOXA6	homeobox A6	0.101
FEZF2	FEZ family zinc finger 2	0.100
NOTCH2	notch 2	0.100	Fly
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.099
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.099
GJA3	gap junction protein, alpha 3, 46kDa	0.098
PSEN2	presenilin 2 (Alzheimer disease 4)	0.097
CALCR	calcitonin receptor	0.097
GGN	gametogenetin	0.096
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.096
SMO	smoothened homolog (Drosophila)	0.096
CRYBA2	crystallin, beta A2	0.096
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.096
HOXA5	homeobox A5	0.095
OTOP1	otopetrin 1	0.095
SPRY2	sprouty homolog 2 (Drosophila)	0.095
BARX1	BARX homeobox 1	0.095
FGFR4	fibroblast growth factor receptor 4	0.095	Mouse
PAX9	paired box 9	0.095
FAM110C	family with sequence similarity 110, member C	0.094
KCNK4	potassium channel, subfamily K, member 4	0.094
ASB7	ankyrin repeat and SOCS box containing 7	0.093
BAHD1	bromo adjacent homology domain containing 1	0.093
NOSTRIN	nitric oxide synthase trafficker	0.093
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.093
KCNT1	potassium channel, subfamily T, member 1	0.092
CRLF1	cytokine receptor-like factor 1	0.092
HOXB8	homeobox B8	0.091
NEUROD2	neurogenic differentiation 2	0.091
ISL1	ISL LIM homeobox 1	0.091
NBN	nibrin	0.091
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.090
DLX5	distal-less homeobox 5	0.090
EXOC3L2	exocyst complex component 3-like 2	0.090
PRDM13	PR domain containing 13	0.089
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.089
BARHL2	BarH-like homeobox 2	0.089	Fly
NTN1	netrin 1	0.089	Fly
POU3F4	POU class 3 homeobox 4	0.089
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.089
ASB2	ankyrin repeat and SOCS box containing 2	0.089
LCORL	ligand dependent nuclear receptor corepressor-like	0.088
TACR1	tachykinin receptor 1	0.088
CYP26C1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.088
ITGA7	integrin, alpha 7	0.088
FXYD3	FXYD domain containing ion transport regulator 3	0.088
INSM2	insulinoma-associated 2	0.087
PRRX1	paired related homeobox 1	0.087
EGFL7	EGF-like-domain, multiple 7	0.087
B4GALNT2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.086
OPRD1	opioid receptor, delta 1	0.086
TWIST1	twist homolog 1 (Drosophila)	0.086
DMRT3	doublesex and mab-3 related transcription factor 3	0.085
NRTN	neurturin	0.085
WNT11	wingless-type MMTV integration site family, member 11	0.085
EFNA2	ephrin-A2	0.085
FGF20	fibroblast growth factor 20	0.085	Human
POU2F3	POU class 2 homeobox 3	0.084
KRT6C	keratin 6C	0.084
INHBB	inhibin, beta B	0.084
GHSR	growth hormone secretagogue receptor	0.083
NKD1	naked cuticle homolog 1 (Drosophila)	0.083
TLX1	T-cell leukemia homeobox 1	0.083	Mouse
PPARG	peroxisome proliferator-activated receptor gamma	0.083
DSP	desmoplakin	0.083
JPH3	junctophilin 3	0.083
SFRP1	secreted frizzled-related protein 1	0.082
PTH2	parathyroid hormone 2	0.082
EPHA8	EPH receptor A8	0.082
HES1	hairy and enhancer of split 1, (Drosophila)	0.082	Mouse
ALX1	ALX homeobox 1	0.082
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.081
APC2	adenomatosis polyposis coli 2	0.081
ARX	aristaless related homeobox	0.081
REM1	RAS (RAD and GEM)-like GTP-binding 1	0.081
SIRT1	sirtuin 1	0.080
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.080
DCUN1D5	DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)	0.080
ACVR1	activin A receptor, type I	0.080
DCX	doublecortin	0.080
FAM110A	family with sequence similarity 110, member A	0.080
HR	hairless homolog (mouse)	0.080
FOXB2	forkhead box B2	0.079
RARA	retinoic acid receptor, alpha	0.079
PECAM1	platelet/endothelial cell adhesion molecule	0.078
CBX2	chromobox homolog 2	0.078
LHX2	LIM homeobox 2	0.078	Human
BCL2L10	BCL2-like 10 (apoptosis facilitator)	0.078
SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)	0.078
PER1	period homolog 1 (Drosophila)	0.078
C1orf187	chromosome 1 open reading frame 187	0.077
SPTBN1	spectrin, beta, non-erythrocytic 1	0.077
MADCAM1	mucosal vascular addressin cell adhesion molecule 1	0.077
SHOX2	short stature homeobox 2	0.077
SHB	Src homology 2 domain containing adaptor protein B	0.077
PHOX2B	paired-like homeobox 2b	0.077
HNF1A	HNF1 homeobox A	0.077
TBX20	T-box 20	0.076
HOXD8	homeobox D8	0.076
FGF19	fibroblast growth factor 19	0.076
FGF18	fibroblast growth factor 18	0.076
SOX17	SRY (sex determining region Y)-box 17	0.076
HOXA2	homeobox A2	0.075
IRX5	iroquois homeobox 5	0.075
DMBX1	diencephalon/mesencephalon homeobox 1	0.075
GRIK3	glutamate receptor, ionotropic, kainate 3	0.075
AMELX	amelogenin, X-linked	0.075
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.075
UNC5A	unc-5 homolog A (C. elegans)	0.075	Fly
RSPO1	R-spondin homolog (Xenopus laevis)	0.075
OVOL1	ovo-like 1(Drosophila)	0.075
EN1	engrailed homeobox 1	0.074
NKPD1	NTPase, KAP family P-loop domain containing 1	0.074
NELL1	NEL-like 1 (chicken)	0.074
EMID2	EMI domain containing 2	0.074
SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.074
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.073
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.073
NRG2	neuregulin 2	0.073
RBBP8	retinoblastoma binding protein 8	0.073
FGF5	fibroblast growth factor 5	0.073	Human
COL4A6	collagen, type IV, alpha 6	0.073
AQP5	aquaporin 5	0.072
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.072
CARD10	caspase recruitment domain family, member 10	0.072
OTX1	orthodenticle homeobox 1	0.072
FZD10	frizzled homolog 10 (Drosophila)	0.072
KAL1	Kallmann syndrome 1 sequence	0.072
OLIG3	oligodendrocyte transcription factor 3	0.071
DLX3	distal-less homeobox 3	0.071
PDGFA	platelet-derived growth factor alpha polypeptide	0.071
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.071
HOXD4	homeobox D4	0.071
NKX2-2	NK2 homeobox 2	0.071
ASB1	ankyrin repeat and SOCS box containing 1	0.071
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.071
EFNB1	ephrin-B1	0.071
TIGD3	tigger transposable element derived 3	0.070
ZNF219	zinc finger protein 219	0.070
FIBCD1	fibrinogen C domain containing 1	0.070
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.070
TERT	telomerase reverse transcriptase	0.070
MMD2	monocyte to macrophage differentiation-associated 2	0.069
RFX2	regulatory factor X, 2 (influences HLA class II expression)	0.069
GALR1	galanin receptor 1	0.069
LHX9	LIM homeobox 9	0.069	Human
TRPM3	transient receptor potential cation channel, subfamily M, member 3	0.069
BBS1	Bardet-Biedl syndrome 1	0.069
WNT9B	wingless-type MMTV integration site family, member 9B	0.068
MSX2	msh homeobox 2	0.068
SORBS3	sorbin and SH3 domain containing 3	0.068
KCNK2	potassium channel, subfamily K, member 2	0.068
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.068
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.068
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.068
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.067
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.067
GLI2	GLI family zinc finger 2	0.067	Mouse Fly
PRRX2	paired related homeobox 2	0.067
IFI16	interferon, gamma-inducible protein 16	0.067
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.067
HAS2	hyaluronan synthase 2	0.067
GDF6	growth differentiation factor 6	0.067
HES7	hairy and enhancer of split 7 (Drosophila)	0.067	Fly
TGFBR3	transforming growth factor, beta receptor III	0.067
CD70	CD70 molecule	0.066
BMPR1B	bone morphogenetic protein receptor, type IB	0.066
ERAS	ES cell expressed Ras	0.066
RNF7	ring finger protein 7	0.066
ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4	0.066
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.066
PBX1	pre-B-cell leukemia homeobox 1	0.065
PROX1	prospero homeobox 1	0.065
KY	kyphoscoliosis peptidase	0.065
RBMXL2	RNA binding motif protein, X-linked-like 2	0.065
NGF	nerve growth factor (beta polypeptide)	0.065
RTN4RL2	reticulon 4 receptor-like 2	0.064
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.064
C8orf84	chromosome 8 open reading frame 84	0.064
FZD2	frizzled homolog 2 (Drosophila)	0.064
DLX1	distal-less homeobox 1	0.064	Fly
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.064
OCLN	occludin	0.064
C2orf55	chromosome 2 open reading frame 55	0.064
NOL4	nucleolar protein 4	0.064
NPAS4	neuronal PAS domain protein 4	0.064
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.063
SAMD11	sterile alpha motif domain containing 11	0.063
KRT34	keratin 34	0.063
HOXA7	homeobox A7	0.063
BNC2	basonuclin 2	0.063
OTOP2	otopetrin 2	0.063
PCDH17	protocadherin 17	0.063
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.062
AJAP1	adherens junctions associated protein 1	0.061
KLF14	Kruppel-like factor 14	0.061
C9orf96	chromosome 9 open reading frame 96	0.061
HES3	hairy and enhancer of split 3 (Drosophila)	0.061	Fly
PXN	paxillin	0.061
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.061
HMX2	H6 family homeobox 2	0.061
AFF2	AF4/FMR2 family, member 2	0.061
GPRIN1	G protein regulated inducer of neurite outgrowth 1	0.061
WNT10B	wingless-type MMTV integration site family, member 10B	0.060
CEP70	centrosomal protein 70kDa	0.060
HOXA3	homeobox A3	0.060	Mouse
SALL2	sal-like 2 (Drosophila)	0.060
WNT4	wingless-type MMTV integration site family, member 4	0.060
OCA2	oculocutaneous albinism II	0.060
KCNRG	potassium channel regulator	0.060
ISL2	ISL LIM homeobox 2	0.060	Human
ZFP28	zinc finger protein 28 homolog (mouse)	0.059
KRTAP4-12	keratin associated protein 4-12	0.059
MYST2	MYST histone acetyltransferase 2	0.058	Fly
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.058
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.058
FAM123C	family with sequence similarity 123C	0.058
EPHA5	EPH receptor A5	0.058
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.057
TRPM1	transient receptor potential cation channel, subfamily M, member 1	0.057
LHX4	LIM homeobox 4	0.057	Human
DDR1	discoidin domain receptor tyrosine kinase 1	0.057
C20orf24	chromosome 20 open reading frame 24	0.056
EPHA2	EPH receptor A2	0.056
BARX2	BARX homeobox 2	0.056
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.056
IGFBP5	insulin-like growth factor binding protein 5	0.056
SALL4	sal-like 4 (Drosophila)	0.056
RHO	rhodopsin	0.056
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.056
XIAP	X-linked inhibitor of apoptosis	0.056
CSNK1D	casein kinase 1, delta	0.056
CLDN4	claudin 4	0.056
HOXC6	homeobox C6	0.055
NKX2-4	NK2 homeobox 4	0.055
AANAT	aralkylamine N-acetyltransferase	0.055
TCF21	transcription factor 21	0.055
KLK4	kallikrein-related peptidase 4	0.055
E2F2	E2F transcription factor 2	0.055
BTBD2	BTB (POZ) domain containing 2	0.055
TBX3	T-box 3	0.055
SP5	Sp5 transcription factor	0.055
NGB	neuroglobin	0.054
KCNK9	potassium channel, subfamily K, member 9	0.054
PRDM14	PR domain containing 14	0.054
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.054	Zebrafish Fly
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.054
SCUBE3	signal peptide, CUB domain, EGF-like 3	0.054
EFNB2	ephrin-B2	0.054
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.054
BMP8B	bone morphogenetic protein 8b	0.054
EBF3	early B-cell factor 3	0.054
BDNF	brain-derived neurotrophic factor	0.054
TRIL	TLR4 interactor with leucine-rich repeats	0.053
DLL4	delta-like 4 (Drosophila)	0.053
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.053
WNT2	wingless-type MMTV integration site family member 2	0.053
UNC5B	unc-5 homolog B (C. elegans)	0.053	Fly
ZAR1	zygote arrest 1	0.053
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.053
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.053
WNT5A	wingless-type MMTV integration site family, member 5A	0.053	Mouse
CHD3	chromodomain helicase DNA binding protein 3	0.053
TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.053
GCLM	glutamate-cysteine ligase, modifier subunit	0.053
NEUROD1	neurogenic differentiation 1	0.052
OTOP3	otopetrin 3	0.052
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.052
SALL1	sal-like 1 (Drosophila)	0.052
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.052
VSTM2B	V-set and transmembrane domain containing 2B	0.052
CCNK	cyclin K	0.052
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.052
BMP6	bone morphogenetic protein 6	0.052
HMX1	H6 family homeobox 1	0.052
CCDC140	coiled-coil domain containing 140	0.052
CHD5	chromodomain helicase DNA binding protein 5	0.052
UNCX	UNC homeobox	0.052
PRDM6	PR domain containing 6	0.052
L1TD1	LINE-1 type transposase domain containing 1	0.052
CTGF	connective tissue growth factor	0.052
HCRTR1	hypocretin (orexin) receptor 1	0.052
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.052
TAS1R1	taste receptor, type 1, member 1	0.052
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.051
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.051
INSM1	insulinoma-associated 1	0.051
VGLL2	vestigial like 2 (Drosophila)	0.051
RUNX2	runt-related transcription factor 2	0.051
HIGD1A	HIG1 hypoxia inducible domain family, member 1A	0.051
SOX14	SRY (sex determining region Y)-box 14	0.051
GPR50	G protein-coupled receptor 50	0.051
SIM1	single-minded homolog 1 (Drosophila)	0.051
ADRA1A	adrenergic, alpha-1A-, receptor	0.051
CDX1	caudal type homeobox 1	0.051
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.051
TTPA	tocopherol (alpha) transfer protein	0.051
CDX4	caudal type homeobox 4	0.051
ZFPM2	zinc finger protein, multitype 2	0.051
GALR2	galanin receptor 2	0.051
GJC2	gap junction protein, gamma 2, 47kDa	0.051
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.051
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.051
SHH	sonic hedgehog	0.050
LZTS1	leucine zipper, putative tumor suppressor 1	0.050
IRX2	iroquois homeobox 2	0.050
RBPJL	recombination signal binding protein for immunoglobulin kappa J region-like	0.050
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.050
CCND1	cyclin D1	0.050
C16orf48	chromosome 16 open reading frame 48	0.050
ADRB3	adrenergic, beta-3-, receptor	0.050
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.050
TLL1	tolloid-like 1	0.050
PRMT2	protein arginine methyltransferase 2	0.050
ZNF775	zinc finger protein 775	0.050
DPF1	D4, zinc and double PHD fingers family 1	0.050
ULBP1	UL16 binding protein 1	0.050
WNT5B	wingless-type MMTV integration site family, member 5B	0.050
APLN	apelin	0.049
MECOM	MDS1 and EVI1 complex locus	0.049
RET	ret proto-oncogene	0.049
GAS1	growth arrest-specific 1	0.049
TAL1	T-cell acute lymphocytic leukemia 1	0.049
FOXL2	forkhead box L2	0.049
CALR	calreticulin	0.049
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.049
CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.049
GNG13	guanine nucleotide binding protein (G protein), gamma 13	0.049
EPHA3	EPH receptor A3	0.049
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.049
C19orf26	chromosome 19 open reading frame 26	0.049
SOBP	sine oculis binding protein homolog (Drosophila)	0.048
KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.048
ADARB2	adenosine deaminase, RNA-specific, B2	0.048
NPAS3	neuronal PAS domain protein 3	0.048
AVPR2	arginine vasopressin receptor 2	0.048
LMO1	LIM domain only 1 (rhombotin 1)	0.048
NXPH2	neurexophilin 2	0.048
PDE10A	phosphodiesterase 10A	0.048
F3	coagulation factor III (thromboplastin, tissue factor)	0.048
JMJD1C	jumonji domain containing 1C	0.048
SLIT2	slit homolog 2 (Drosophila)	0.048	Zebrafish Fly
CHAT	choline O-acetyltransferase	0.048
HOXB4	homeobox B4	0.047
SALL3	sal-like 3 (Drosophila)	0.047
ITGB1BP1	integrin beta 1 binding protein 1	0.047
ZNF408	zinc finger protein 408	0.047
LINGO3	leucine rich repeat and Ig domain containing 3	0.047
RFX4	regulatory factor X, 4 (influences HLA class II expression)	0.047
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.047
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.047
PRAC	prostate cancer susceptibility candidate	0.047
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.047
DUSP9	dual specificity phosphatase 9	0.047
MATN4	matrilin 4	0.047
ACAN	aggrecan	0.047
DBX1	developing brain homeobox 1	0.047
RGS9BP	regulator of G protein signaling 9 binding protein	0.047
APC	adenomatous polyposis coli	0.047
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.046
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.046
LY6H	lymphocyte antigen 6 complex, locus H	0.046
OAF	OAF homolog (Drosophila)	0.046
HELT	HES/HEY-like transcription factor	0.046
FOXJ1	forkhead box J1	0.046
FGD1	FYVE, RhoGEF and PH domain containing 1	0.046
MYLK2	myosin light chain kinase 2	0.046
CSMD2	CUB and Sushi multiple domains 2	0.046
TFAP2E	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)	0.046
ZNF503	zinc finger protein 503	0.046
NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	0.046
SIX5	SIX homeobox 5	0.046
NRP1	neuropilin 1	0.046
BTBD1	BTB (POZ) domain containing 1	0.046
LHX8	LIM homeobox 8	0.045	Human
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.045
VIP	vasoactive intestinal peptide	0.045
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.045
GYLTL1B	glycosyltransferase-like 1B	0.045
EMX2	empty spiracles homeobox 2	0.045
PGM5	phosphoglucomutase 5	0.045
MN1	meningioma (disrupted in balanced translocation) 1	0.045
MOS	v-mos Moloney murine sarcoma viral oncogene homolog	0.045
ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	0.045
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.045
GRM6	glutamate receptor, metabotropic 6	0.045
PTH	parathyroid hormone	0.045
LRIT1	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	0.045
KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.045
NOS1	nitric oxide synthase 1 (neuronal)	0.044
GPR124	G protein-coupled receptor 124	0.044
OMP	olfactory marker protein	0.044
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.044
FGF22	fibroblast growth factor 22	0.044	Human
HUNK	hormonally up-regulated Neu-associated kinase	0.044
PRKG1	protein kinase, cGMP-dependent, type I	0.044
MYL12B	myosin, light chain 12B, regulatory	0.044
CD63	CD63 molecule	0.044
FAM43B	family with sequence similarity 43, member B	0.044
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.044
NPPC	natriuretic peptide C	0.044
SMAD3	SMAD family member 3	0.044
KCNK15	potassium channel, subfamily K, member 15	0.044
PCDHB11	protocadherin beta 11	0.044
BTG2	BTG family, member 2	0.044
EPO	erythropoietin	0.044
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.044
GRP	gastrin-releasing peptide	0.044
NT5C1A	5'-nucleotidase, cytosolic IA	0.044
GAB2	GRB2-associated binding protein 2	0.044
PTHLH	parathyroid hormone-like hormone	0.044
LTK	leukocyte receptor tyrosine kinase	0.044
SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.044
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.044
CD34	CD34 molecule	0.043
CRH	corticotropin releasing hormone	0.043
SYT12	synaptotagmin XII	0.043
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.043
FBN2	fibrillin 2	0.043
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.043
GPR161	G protein-coupled receptor 161	0.043
RB1	retinoblastoma 1	0.043
DPYSL5	dihydropyrimidinase-like 5	0.043
BHLHE22	basic helix-loop-helix family, member e22	0.043
GFRA3	GDNF family receptor alpha 3	0.043
ONECUT1	one cut homeobox 1	0.043