IMP: Integrative Multi-species Prediction

Homo sapiens

37 genes annotated in human

cellular response to steroid hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to steroid hormone stimulus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular response to steroid hormone stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
ESR1	estrogen receptor 1	0.899
EGFR	epidermal growth factor receptor	0.839
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.701
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.672	Human
CREBBP	CREB binding protein	0.583
SMN1	survival of motor neuron 1, telomeric	0.494
SMAD4	SMAD family member 4	0.312
FSTL1	follistatin-like 1	0.296
PPARA	peroxisome proliferator-activated receptor alpha	0.296
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.285
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.223	Human
NRP1	neuropilin 1	0.192
BMPR1A	bone morphogenetic protein receptor, type IA	0.182
ARIH2	ariadne homolog 2 (Drosophila)	0.181
CDK11B	cyclin-dependent kinase 11B	0.177
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.176	Human
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.176
BMPR1B	bone morphogenetic protein receptor, type IB	0.173
S100A10	S100 calcium binding protein A10	0.171
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.140
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.140
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.137
RNF144B	ring finger protein 144B	0.136
APAF1	apoptotic peptidase activating factor 1	0.128
CAV1	caveolin 1, caveolae protein, 22kDa	0.120
NCOA1	nuclear receptor coactivator 1	0.118
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.116
BRCA1	breast cancer 1, early onset	0.115
PDCD6	programmed cell death 6	0.105
HDAC1	histone deacetylase 1	0.104
AR	androgen receptor	0.102
PLAU	plasminogen activator, urokinase	0.098
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.096
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.091
CUEDC2	CUE domain containing 2	0.087
KLHL24	kelch-like 24 (Drosophila)	0.086
PLAT	plasminogen activator, tissue	0.081	Rat
RUVBL1	RuvB-like 1 (E. coli)	0.078
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.078
NCOR2	nuclear receptor corepressor 2	0.077
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.077	Human
CBX1	chromobox homolog 1	0.072
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.067	Rat
RXRA	retinoid X receptor, alpha	0.065
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.064
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	0.058
ANXA1	annexin A1	0.057
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.056
TP53	tumor protein p53	0.053
ANXA2	annexin A2	0.053	Human
DUSP6	dual specificity phosphatase 6	0.052
JDP2	Jun dimerization protein 2	0.051
NMI	N-myc (and STAT) interactor	0.050
MED1	mediator complex subunit 1	0.048
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.047
TIMP2	TIMP metallopeptidase inhibitor 2	0.046
STAT5A	signal transducer and activator of transcription 5A	0.046
INSR	insulin receptor	0.042
NCOA2	nuclear receptor coactivator 2	0.042
IFNGR1	interferon gamma receptor 1	0.042
NCOA3	nuclear receptor coactivator 3	0.041
IL10RA	interleukin 10 receptor, alpha	0.041
IGF1R	insulin-like growth factor 1 receptor	0.039
ARNT	aryl hydrocarbon receptor nuclear translocator	0.038
EMP1	epithelial membrane protein 1	0.037
S100A11	S100 calcium binding protein A11	0.037
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.037	Human
CRHR1	corticotropin releasing hormone receptor 1	0.036
S100A6	S100 calcium binding protein A6	0.036
SOCS3	suppressor of cytokine signaling 3	0.034
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.033
PLAUR	plasminogen activator, urokinase receptor	0.033
THBS1	thrombospondin 1	0.033
SMAD9	SMAD family member 9	0.032
IQGAP1	IQ motif containing GTPase activating protein 1	0.032
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.032
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.032
FN1	fibronectin 1	0.031
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.031
FADD	Fas (TNFRSF6)-associated via death domain	0.030
FAM46A	family with sequence similarity 46, member A	0.030
RARA	retinoic acid receptor, alpha	0.029
ESR2	estrogen receptor 2 (ER beta)	0.029	Human Zebrafish Rat
EGR3	early growth response 3	0.029
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.029
ZFYVE9	zinc finger, FYVE domain containing 9	0.028
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.028
PPP5C	protein phosphatase 5, catalytic subunit	0.028
NOG	noggin	0.028
TRADD	TNFRSF1A-associated via death domain	0.027
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.027
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.027
ENG	endoglin	0.027
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.027
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.027
HNF4A	hepatocyte nuclear factor 4, alpha	0.026
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.025
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.025
SOCS1	suppressor of cytokine signaling 1	0.025
PGF	placental growth factor	0.025
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.025
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.024
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.024
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.024
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.024
TGFB3	transforming growth factor, beta 3	0.024
XIAP	X-linked inhibitor of apoptosis	0.024
LAT	linker for activation of T cells	0.023
FOXO1	forkhead box O1	0.023
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.023
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.023
NRIP1	nuclear receptor interacting protein 1	0.023
SPDEF	SAM pointed domain containing ets transcription factor	0.022
SKIL	SKI-like oncogene	0.022
TCF4	transcription factor 4	0.022
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.022
SNAI1	snail homolog 1 (Drosophila)	0.022
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.022
C16orf53	chromosome 16 open reading frame 53	0.021
PRMT2	protein arginine methyltransferase 2	0.021
MPDZ	multiple PDZ domain protein	0.021
PML	promyelocytic leukemia	0.021
ACACA	acetyl-CoA carboxylase alpha	0.021
BAX	BCL2-associated X protein	0.021
TSC22D1	TSC22 domain family, member 1	0.021
EGR2	early growth response 2	0.020
SSR2	signal sequence receptor, beta (translocon-associated protein beta)	0.020
FKBP2	FK506 binding protein 2, 13kDa	0.020
EMP3	epithelial membrane protein 3	0.019
HIPK2	homeodomain interacting protein kinase 2	0.019
MYOD1	myogenic differentiation 1	0.019	Mouse
TK1	thymidine kinase 1, soluble	0.019
H3F3C	H3 histone, family 3C	0.019
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.019
NPC2	Niemann-Pick disease, type C2	0.019
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.019
PAX7	paired box 7	0.019
ARRDC3	arrestin domain containing 3	0.019
RPN2	ribophorin II	0.018
DDR2	discoidin domain receptor tyrosine kinase 2	0.018
GSN	gelsolin	0.018
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.018
GABARAP	GABA(A) receptor-associated protein	0.018
NCOA7	nuclear receptor coactivator 7	0.018
ANXA4	annexin A4	0.018	Human
ACTR6	ARP6 actin-related protein 6 homolog (yeast)	0.018
DMAP1	DNA methyltransferase 1 associated protein 1	0.018
CBX5	chromobox homolog 5	0.018
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.018	Human
LGALS3	lectin, galactoside-binding, soluble, 3	0.017
TTN	titin	0.017
SYK	spleen tyrosine kinase	0.017
SSTR2	somatostatin receptor 2	0.016	Rat
HDAC3	histone deacetylase 3	0.016
HIC1	hypermethylated in cancer 1	0.016
APP	amyloid beta (A4) precursor protein	0.016
MED25	mediator complex subunit 25	0.016
HRG	histidine-rich glycoprotein	0.016
LAS1L	LAS1-like (S. cerevisiae)	0.016
PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.016
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.016
KLF9	Kruppel-like factor 9	0.016
WWOX	WW domain containing oxidoreductase	0.016
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.015
TMSB10	thymosin beta 10	0.015
NOMO1	NODAL modulator 1	0.015
HMGN2	high mobility group nucleosomal binding domain 2	0.015
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.015	Human
MYOZ1	myozenin 1	0.015
VEZF1	vascular endothelial zinc finger 1	0.015
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.015
RET	ret proto-oncogene	0.015
TM4SF1	transmembrane 4 L six family member 1	0.015
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.015
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.014
TIMP3	TIMP metallopeptidase inhibitor 3	0.014
LGALS1	lectin, galactoside-binding, soluble, 1	0.014
GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.014
MYLK2	myosin light chain kinase 2	0.014
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.014
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.014
EP300	E1A binding protein p300	0.014
MAPK1	mitogen-activated protein kinase 1	0.014
CDK19	cyclin-dependent kinase 19	0.014
SEC61B	Sec61 beta subunit	0.014
ANXA5	annexin A5	0.014	Human
THBS2	thrombospondin 2	0.014
SP1	Sp1 transcription factor	0.014
EPOR	erythropoietin receptor	0.013
CFLAR	CASP8 and FADD-like apoptosis regulator	0.013
CD34	CD34 molecule	0.013
GBP2	guanylate binding protein 2, interferon-inducible	0.013
AHR	aryl hydrocarbon receptor	0.013	Rat
APOD	apolipoprotein D	0.013
TRIM43	tripartite motif containing 43	0.013
ITGB5	integrin, beta 5	0.013
GRIP1	glutamate receptor interacting protein 1	0.013
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.013	Human
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.013
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.013
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.013	Zebrafish Mouse Rat
ADAMTSL4	ADAMTS-like 4	0.013
SMAD2	SMAD family member 2	0.013
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.013
DES	desmin	0.013
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.013
TRIM24	tripartite motif containing 24	0.013
FHL2	four and a half LIM domains 2	0.013
RNF31	ring finger protein 31	0.013
TRO	trophinin	0.012
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.012
NEB	nebulin	0.012
MED13L	mediator complex subunit 13-like	0.012
SFRP1	secreted frizzled-related protein 1	0.012
SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.012
GHR	growth hormone receptor	0.012
BCL2	B-cell CLL/lymphoma 2	0.012
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.012
ACTA1	actin, alpha 1, skeletal muscle	0.012
DLG2	discs, large homolog 2 (Drosophila)	0.012
FASLG	Fas ligand (TNF superfamily, member 6)	0.012
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.012
ADAM9	ADAM metallopeptidase domain 9	0.012
JAK2	Janus kinase 2	0.012	Mouse
POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	0.012
CD63	CD63 molecule	0.012
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.012
ORM1	orosomucoid 1	0.012
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.012
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.012
C20orf20	chromosome 20 open reading frame 20	0.012
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.012
MAGEA2	melanoma antigen family A, 2	0.012
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.012
TP73	tumor protein p73	0.012
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.012
BID	BH3 interacting domain death agonist	0.012
RARB	retinoic acid receptor, beta	0.012	Human
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.012
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.011
TFPI2	tissue factor pathway inhibitor 2	0.011
PIAS2	protein inhibitor of activated STAT, 2	0.011
MSX1	msh homeobox 1	0.011
FAM107A	family with sequence similarity 107, member A	0.011
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.011
CCND3	cyclin D3	0.011
NDRG1	N-myc downstream regulated 1	0.011
TAT	tyrosine aminotransferase	0.011
PRMT6	protein arginine methyltransferase 6	0.011
NMT2	N-myristoyltransferase 2	0.011
KCTD17	potassium channel tetramerisation domain containing 17	0.011
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.011
LBR	lamin B receptor	0.011
IGFBP5	insulin-like growth factor binding protein 5	0.011
FOXA1	forkhead box A1	0.011
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.011
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.011
NCOR1	nuclear receptor corepressor 1	0.011
PTHLH	parathyroid hormone-like hormone	0.011
WNT2	wingless-type MMTV integration site family member 2	0.011
SMAD7	SMAD family member 7	0.011
TIMP1	TIMP metallopeptidase inhibitor 1	0.011
ZMYND11	zinc finger, MYND-type containing 11	0.011
BCL6	B-cell CLL/lymphoma 6	0.011
SPRY2	sprouty homolog 2 (Drosophila)	0.010
GLIS2	GLIS family zinc finger 2	0.010
PRDX4	peroxiredoxin 4	0.010
DLG4	discs, large homolog 4 (Drosophila)	0.010
MAPK14	mitogen-activated protein kinase 14	0.010
TGFBR1	transforming growth factor, beta receptor 1	0.010
PNRC1	proline-rich nuclear receptor coactivator 1	0.010
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.010
BCAR1	breast cancer anti-estrogen resistance 1	0.010
PTPRB	protein tyrosine phosphatase, receptor type, B	0.010
BARD1	BRCA1 associated RING domain 1	0.010
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.010
ING3	inhibitor of growth family, member 3	0.010
DAD1	defender against cell death 1	0.010
MYOF	myoferlin	0.010
PSIP1	PC4 and SFRS1 interacting protein 1	0.010
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.010	Rat
ANKRD12	ankyrin repeat domain 12	0.010
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.010