IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

hindbrain development

The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hindbrain development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "hindbrain development" (in gray)

Name	Description	Probability	Func Analog Organism
EP300	E1A binding protein p300	0.999
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.999
JAG1	jagged 1	0.995
ESR1	estrogen receptor 1	0.993
EGFR	epidermal growth factor receptor	0.993
AR	androgen receptor	0.989
NCOA1	nuclear receptor coactivator 1	0.977
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.973
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.970
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.967
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.954
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.945
FGFR1	fibroblast growth factor receptor 1	0.932
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.908
SETD8	SET domain containing (lysine methyltransferase) 8	0.899
INADL	InaD-like (Drosophila)	0.897
HNF4A	hepatocyte nuclear factor 4, alpha	0.848
APC	adenomatous polyposis coli	0.831	Fly
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.828
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.811
PDZD11	PDZ domain containing 11	0.810
GSK3B	glycogen synthase kinase 3 beta	0.809
ATXN1	ataxin 1	0.802
PDX1	pancreatic and duodenal homeobox 1	0.784
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.782
SMAD3	SMAD family member 3	0.781
TAL1	T-cell acute lymphocytic leukemia 1	0.756	Human
MPDZ	multiple PDZ domain protein	0.737
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.732
TRRAP	transformation/transcription domain-associated protein	0.717
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	0.708
ARID1A	AT rich interactive domain 1A (SWI-like)	0.705
RPL18A	ribosomal protein L18a	0.703
TCF4	transcription factor 4	0.698
TP53	tumor protein p53	0.692	Mouse
BCOR	BCL6 corepressor	0.692
ASB2	ankyrin repeat and SOCS box containing 2	0.688
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.679
CHDH	choline dehydrogenase	0.667
QKI	quaking homolog, KH domain RNA binding (mouse)	0.656
RBPMS	RNA binding protein with multiple splicing	0.644
GATA2	GATA binding protein 2	0.642	Mouse
RUNX1	runt-related transcription factor 1	0.634
PBX1	pre-B-cell leukemia homeobox 1	0.611
EGR1	early growth response 1	0.605
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.596
NCOR1	nuclear receptor corepressor 1	0.582	Zebrafish
PTCH1	patched 1	0.581
GATA4	GATA binding protein 4	0.581
SNTG2	syntrophin, gamma 2	0.580
LMO4	LIM domain only 4	0.564
TESK1	testis-specific kinase 1	0.537
SH3KBP1	SH3-domain kinase binding protein 1	0.536
SOX1	SRY (sex determining region Y)-box 1	0.522
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.508
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.503
SOX11	SRY (sex determining region Y)-box 11	0.478
SIX6	SIX homeobox 6	0.467
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.467
SIRT1	sirtuin 1	0.450
GRB7	growth factor receptor-bound protein 7	0.449
SUFU	suppressor of fused homolog (Drosophila)	0.447
HTT	huntingtin	0.442
EGR3	early growth response 3	0.439
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.439
ONECUT1	one cut homeobox 1	0.423
ATN1	atrophin 1	0.419
MYOD1	myogenic differentiation 1	0.408
NEUROD1	neurogenic differentiation 1	0.383	Human Mouse Rat
PAX6	paired box 6	0.377	Zebrafish Rat
NRXN1	neurexin 1	0.376	Mouse
GLIS2	GLIS family zinc finger 2	0.375
TRIP6	thyroid hormone receptor interactor 6	0.373
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.366	Zebrafish
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.366
FOXA2	forkhead box A2	0.365	Mouse
HNF1A	HNF1 homeobox A	0.363
CREBBP	CREB binding protein	0.359
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.356	Mouse
FHL2	four and a half LIM domains 2	0.351
RAX	retina and anterior neural fold homeobox	0.344
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.341
SP1	Sp1 transcription factor	0.340
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.336
SESN2	sestrin 2	0.335
ERBB2IP	erbb2 interacting protein	0.326
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.323
POU4F2	POU class 4 homeobox 2	0.323
RXRA	retinoid X receptor, alpha	0.321
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.320
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.319
TUBB2B	tubulin, beta 2B	0.319
RIN1	Ras and Rab interactor 1	0.318
BMP7	bone morphogenetic protein 7	0.311
RANBP9	RAN binding protein 9	0.311
APLP1	amyloid beta (A4) precursor-like protein 1	0.310
HOXD12	homeobox D12	0.309
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.306
SIX3	SIX homeobox 3	0.306
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.304
NDP	Norrie disease (pseudoglioma)	0.302
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.299
CDX2	caudal type homeobox 2	0.293
CUL5	cullin 5	0.287	Mouse
SMAD5	SMAD family member 5	0.279
ACACA	acetyl-CoA carboxylase alpha	0.278
HOXB5	homeobox B5	0.278
OTP	orthopedia homeobox	0.276
BMP2	bone morphogenetic protein 2	0.275
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.271
PAX7	paired box 7	0.270
CHD3	chromodomain helicase DNA binding protein 3	0.264
CALCA	calcitonin-related polypeptide alpha	0.264
MYO16	myosin XVI	0.263	Rat
WNT3A	wingless-type MMTV integration site family, member 3A	0.263
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.261	Zebrafish
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.258
PAX3	paired box 3	0.258
LPHN1	latrophilin 1	0.257
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.257
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.257
BCL2	B-cell CLL/lymphoma 2	0.255	Mouse
POU3F2	POU class 3 homeobox 2	0.251
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.249
HOXA5	homeobox A5	0.248
PAX2	paired box 2	0.247
LBX1	ladybird homeobox 1	0.246
NCOA3	nuclear receptor coactivator 3	0.243
HOXC8	homeobox C8	0.242
LHX3	LIM homeobox 3	0.240
ALX3	ALX homeobox 3	0.240
GBX2	gastrulation brain homeobox 2	0.238	Zebrafish Mouse
MEIS2	Meis homeobox 2	0.238
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.237
TLX2	T-cell leukemia homeobox 2	0.237
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.235
SSTR2	somatostatin receptor 2	0.235	Rat
SORBS3	sorbin and SH3 domain containing 3	0.234
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.234
NKX2-2	NK2 homeobox 2	0.233
MYT1	myelin transcription factor 1	0.232
YAP1	Yes-associated protein 1	0.231
POU4F1	POU class 4 homeobox 1	0.230	Mouse
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.229
FGFR2	fibroblast growth factor receptor 2	0.229
FEV	FEV (ETS oncogene family)	0.225
KCTD1	potassium channel tetramerisation domain containing 1	0.225
MCC	mutated in colorectal cancers	0.225
PXN	paxillin	0.225
HMGA2	high mobility group AT-hook 2	0.224
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.223
POU4F3	POU class 4 homeobox 3	0.222
HOXD13	homeobox D13	0.222
ATXN7	ataxin 7	0.222
SFRP1	secreted frizzled-related protein 1	0.221
CRELD2	cysteine-rich with EGF-like domains 2	0.220
DST	dystonin	0.220
SMAD4	SMAD family member 4	0.219
FERMT2	fermitin family member 2	0.218
HOXA10	homeobox A10	0.215
FZD8	frizzled homolog 8 (Drosophila)	0.215
FEZF2	FEZ family zinc finger 2	0.215
CSNK1E	casein kinase 1, epsilon	0.214
NEUROG1	neurogenin 1	0.213	Human Zebrafish
IARS	isoleucyl-tRNA synthetase	0.210
FOXD3	forkhead box D3	0.210
HIPK2	homeodomain interacting protein kinase 2	0.208
FOXG1	forkhead box G1	0.208
LHX1	LIM homeobox 1	0.206	Mouse
HOXB8	homeobox B8	0.205
HOXA4	homeobox A4	0.205
LPL	lipoprotein lipase	0.203
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.203
EMX1	empty spiracles homeobox 1	0.200
DLL1	delta-like 1 (Drosophila)	0.200
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.198	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.197
PTN	pleiotrophin	0.197
SRRM4	serine/arginine repetitive matrix 4	0.195
TLX1	T-cell leukemia homeobox 1	0.193
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.192
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.192
NEGR1	neuronal growth regulator 1	0.191
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.191	Mouse
FOXC1	forkhead box C1	0.189
FGF3	fibroblast growth factor 3	0.189
MYLK2	myosin light chain kinase 2	0.189
NKX6-1	NK6 homeobox 1	0.189
FOXB1	forkhead box B1	0.189
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.186
LHX2	LIM homeobox 2	0.186
NKX2-1	NK2 homeobox 1	0.186
PAX8	paired box 8	0.186
NFIA	nuclear factor I/A	0.185
TBR1	T-box, brain, 1	0.184
HYOU1	hypoxia up-regulated 1	0.183
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.182
ACTL6B	actin-like 6B	0.181
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.181
NCK2	NCK adaptor protein 2	0.180
NOTCH3	notch 3	0.178	Zebrafish
JAM2	junctional adhesion molecule 2	0.177
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.175
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.174
STRN3	striatin, calmodulin binding protein 3	0.174
ASB7	ankyrin repeat and SOCS box containing 7	0.174
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.174
HOXD9	homeobox D9	0.173
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.173
FBLN1	fibulin 1	0.172
PRKCZ	protein kinase C, zeta	0.170
CELF3	CUGBP, Elav-like family member 3	0.169
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.168
PYY	peptide YY	0.168
HDAC2	histone deacetylase 2	0.166
GRID2IP	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein	0.166
WNT6	wingless-type MMTV integration site family, member 6	0.166
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.165
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.164
HOXB9	homeobox B9	0.164
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.163
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.163
PTHLH	parathyroid hormone-like hormone	0.163
FOXA1	forkhead box A1	0.161
ZMYND11	zinc finger, MYND-type containing 11	0.160
MAPK4	mitogen-activated protein kinase 4	0.159
SOX21	SRY (sex determining region Y)-box 21	0.158
DCX	doublecortin	0.158
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.158
LMO1	LIM domain only 1 (rhombotin 1)	0.157
NLK	nemo-like kinase	0.154
LPXN	leupaxin	0.154
PLCG1	phospholipase C, gamma 1	0.154
BCAR1	breast cancer anti-estrogen resistance 1	0.154
MNX1	motor neuron and pancreas homeobox 1	0.153
OCLN	occludin	0.153
CABLES1	Cdk5 and Abl enzyme substrate 1	0.151
POU3F4	POU class 3 homeobox 4	0.151
USP22	ubiquitin specific peptidase 22	0.148
LSAMP	limbic system-associated membrane protein	0.148
TBX1	T-box 1	0.147
HOXA3	homeobox A3	0.147
SPTBN1	spectrin, beta, non-erythrocytic 1	0.147
CTGF	connective tissue growth factor	0.146
ZNF512B	zinc finger protein 512B	0.145
GARS	glycyl-tRNA synthetase	0.145
GRB10	growth factor receptor-bound protein 10	0.144
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.144
GFAP	glial fibrillary acidic protein	0.143
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.143
TADA2A	transcriptional adaptor 2A	0.143
HAND1	heart and neural crest derivatives expressed 1	0.142	Human
FZD7	frizzled homolog 7 (Drosophila)	0.142
DLG2	discs, large homolog 2 (Drosophila)	0.142
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.141
EN1	engrailed homeobox 1	0.140	Mouse
CAV1	caveolin 1, caveolae protein, 22kDa	0.140
HOXA6	homeobox A6	0.140
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.140
RNF38	ring finger protein 38	0.139
NOVA2	neuro-oncological ventral antigen 2	0.138
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.138
POU3F1	POU class 3 homeobox 1	0.136
MED25	mediator complex subunit 25	0.135
MEOX2	mesenchyme homeobox 2	0.135
SH3BP4	SH3-domain binding protein 4	0.135
LRRK2	leucine-rich repeat kinase 2	0.135
CBY1	chibby homolog 1 (Drosophila)	0.135
PITX2	paired-like homeodomain 2	0.135
ESPN	espin	0.133
HAP1	huntingtin-associated protein 1	0.133
SIM2	single-minded homolog 2 (Drosophila)	0.133
SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.133
NUMBL	numb homolog (Drosophila)-like	0.132
HOXA9	homeobox A9	0.132
ETV5	ets variant 5	0.132
PCGF2	polycomb group ring finger 2	0.130
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.130
COPB1	coatomer protein complex, subunit beta 1	0.130
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.128
PBRM1	polybromo 1	0.128
NCAM1	neural cell adhesion molecule 1	0.127
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.127
SST	somatostatin	0.127
ASNS	asparagine synthetase (glutamine-hydrolyzing)	0.127
CCKBR	cholecystokinin B receptor	0.126
MAST1	microtubule associated serine/threonine kinase 1	0.126
RBBP7	retinoblastoma binding protein 7	0.126
AXIN1	axin 1	0.125
NCOR2	nuclear receptor corepressor 2	0.125
LMO2	LIM domain only 2 (rhombotin-like 1)	0.125
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.125
SOX2	SRY (sex determining region Y)-box 2	0.124
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.124
NUAK1	NUAK family, SNF1-like kinase, 1	0.124
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.124
HAND2	heart and neural crest derivatives expressed 2	0.124	Human
MYH10	myosin, heavy chain 10, non-muscle	0.123	Mouse
C1QL1	complement component 1, q subcomponent-like 1	0.123
ASB1	ankyrin repeat and SOCS box containing 1	0.122
MAPT	microtubule-associated protein tau	0.122
VAX2	ventral anterior homeobox 2	0.121
NPAS1	neuronal PAS domain protein 1	0.121
GABARAPL1	GABA(A) receptor-associated protein like 1	0.121
MAP2K1	mitogen-activated protein kinase kinase 1	0.121
NEUROG3	neurogenin 3	0.121	Human Zebrafish Rat
HES2	hairy and enhancer of split 2 (Drosophila)	0.121
SARS	seryl-tRNA synthetase	0.120
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.119
VHL	von Hippel-Lindau tumor suppressor	0.118
PARVA	parvin, alpha	0.117
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.117
MEIS1	Meis homeobox 1	0.117
STK36	serine/threonine kinase 36	0.117
GRM7	glutamate receptor, metabotropic 7	0.117
SSTR3	somatostatin receptor 3	0.116	Rat
FGF8	fibroblast growth factor 8 (androgen-induced)	0.116
DLL3	delta-like 3 (Drosophila)	0.115
MARS	methionyl-tRNA synthetase	0.115
MSX1	msh homeobox 1	0.115
ULK2	unc-51-like kinase 2 (C. elegans)	0.115
HNF1B	HNF1 homeobox B	0.115	Zebrafish Mouse
IGFBP3	insulin-like growth factor binding protein 3	0.115
FOXF2	forkhead box F2	0.114
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.114
IRX4	iroquois homeobox 4	0.114
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.114
NHLH2	nescient helix loop helix 2	0.114	Human
SFRP5	secreted frizzled-related protein 5	0.114
INSM1	insulinoma-associated 1	0.114
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.113
JAG2	jagged 2	0.113
RNF2	ring finger protein 2	0.112
TP73	tumor protein p73	0.112
GSC	goosecoid homeobox	0.112
OTX2	orthodenticle homeobox 2	0.112	Zebrafish Mouse
HOXB6	homeobox B6	0.112
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.112
COL2A1	collagen, type II, alpha 1	0.111
DLX2	distal-less homeobox 2	0.111
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.111
NRG2	neuregulin 2	0.110
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.110
EN2	engrailed homeobox 2	0.110	Mouse
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.109
FHOD3	formin homology 2 domain containing 3	0.109
IRS4	insulin receptor substrate 4	0.109
ZNF331	zinc finger protein 331	0.109
SOX4	SRY (sex determining region Y)-box 4	0.109
NGFR	nerve growth factor receptor	0.108
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.108
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.107
RET	ret proto-oncogene	0.107
NNAT	neuronatin	0.107
PTPRD	protein tyrosine phosphatase, receptor type, D	0.107
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.106
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.106
PROX1	prospero homeobox 1	0.106	Mouse
BRSK2	BR serine/threonine kinase 2	0.106
GRIN3B	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	0.105
WNT10A	wingless-type MMTV integration site family, member 10A	0.105
ACP5	acid phosphatase 5, tartrate resistant	0.105
ADCY8	adenylate cyclase 8 (brain)	0.105
HOXD3	homeobox D3	0.104
SMAD7	SMAD family member 7	0.104
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.104
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.104
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.104
GSC2	goosecoid homeobox 2	0.104
ARHGAP5	Rho GTPase activating protein 5	0.103
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.103
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.103
ZRANB1	zinc finger, RAN-binding domain containing 1	0.103
CADM4	cell adhesion molecule 4	0.103
NEUROD2	neurogenic differentiation 2	0.103	Human Mouse
PRPH	peripherin	0.102
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.102	Zebrafish Mouse
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.102
LIMS1	LIM and senescent cell antigen-like domains 1	0.102
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.101
CABP1	calcium binding protein 1	0.101
FOXO1	forkhead box O1	0.101
AMN	amnionless homolog (mouse)	0.101
HOXA11	homeobox A11	0.101
MADCAM1	mucosal vascular addressin cell adhesion molecule 1	0.100
GRIK3	glutamate receptor, ionotropic, kainate 3	0.100
ASB6	ankyrin repeat and SOCS box containing 6	0.100
PHOX2A	paired-like homeobox 2a	0.100	Zebrafish Mouse
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.100
SORCS3	sortilin-related VPS10 domain containing receptor 3	0.100
ZFPM1	zinc finger protein, multitype 1	0.100
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.099
MAP3K12	mitogen-activated protein kinase kinase kinase 12	0.099
HOXB4	homeobox B4	0.099
SKIL	SKI-like oncogene	0.099
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.098
FBXO3	F-box protein 3	0.098
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.098
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.098	Mouse
FOXE3	forkhead box E3	0.098
ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4	0.098
POU3F3	POU class 3 homeobox 3	0.097
PITX3	paired-like homeodomain 3	0.097
KDM6A	lysine (K)-specific demethylase 6A	0.097
NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	0.097
GRM1	glutamate receptor, metabotropic 1	0.097
FAF1	Fas (TNFRSF6) associated factor 1	0.097
CLASP2	cytoplasmic linker associated protein 2	0.096
NELL1	NEL-like 1 (chicken)	0.096
VSX2	visual system homeobox 2	0.096
LHX5	LIM homeobox 5	0.096	Mouse
RTKN	rhotekin	0.096
NRIP1	nuclear receptor interacting protein 1	0.095
HEMGN	hemogen	0.095
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.095
TSC2	tuberous sclerosis 2	0.095
GPR6	G protein-coupled receptor 6	0.095
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.095
INHBB	inhibin, beta B	0.095
HDAC4	histone deacetylase 4	0.095
SYN2	synapsin II	0.094
SOX10	SRY (sex determining region Y)-box 10	0.094
IGF1R	insulin-like growth factor 1 receptor	0.093
RASGEF1C	RasGEF domain family, member 1C	0.093
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.093
SOX9	SRY (sex determining region Y)-box 9	0.093
C14orf43	chromosome 14 open reading frame 43	0.093
SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.092
CHD5	chromodomain helicase DNA binding protein 5	0.092
FBXO30	F-box protein 30	0.092
RNF7	ring finger protein 7	0.092	Mouse
ARHGAP22	Rho GTPase activating protein 22	0.091
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.091
AHNAK	AHNAK nucleoprotein	0.091
PRDM12	PR domain containing 12	0.090
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	0.090
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.090
HOXC11	homeobox C11	0.090
NAV3	neuron navigator 3	0.090
PTK6	PTK6 protein tyrosine kinase 6	0.090
MESP1	mesoderm posterior 1 homolog (mouse)	0.090
PRKCI	protein kinase C, iota	0.089	Zebrafish
OLIG2	oligodendrocyte lineage transcription factor 2	0.089	Zebrafish
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.089
ESRRB	estrogen-related receptor beta	0.089
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.089
MAP1B	microtubule-associated protein 1B	0.088
SNAI1	snail homolog 1 (Drosophila)	0.088
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.088
BMP4	bone morphogenetic protein 4	0.088
GFPT1	glutamine--fructose-6-phosphate transaminase 1	0.088
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.088
SIM1	single-minded homolog 1 (Drosophila)	0.087
VCL	vinculin	0.087
LRRN2	leucine rich repeat neuronal 2	0.087
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.087
EPHA4	EPH receptor A4	0.087
CDH5	cadherin 5, type 2 (vascular endothelium)	0.087
CBX8	chromobox homolog 8	0.087
HMX1	H6 family homeobox 1	0.087
NKX3-2	NK3 homeobox 2	0.087
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.086
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.086
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.085
EPHA3	EPH receptor A3	0.085
INA	internexin neuronal intermediate filament protein, alpha	0.085
JPH3	junctophilin 3	0.085
PTF1A	pancreas specific transcription factor, 1a	0.084
SPRY2	sprouty homolog 2 (Drosophila)	0.084
BBS10	Bardet-Biedl syndrome 10	0.084
LPPR1	lipid phosphate phosphatase-related protein type 1	0.083
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.083
GLI3	GLI family zinc finger 3	0.083
HOXB1	homeobox B1	0.083	Zebrafish Mouse
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.083
FOXL1	forkhead box L1	0.083
ISL1	ISL LIM homeobox 1	0.082
TACR3	tachykinin receptor 3	0.082
AFF2	AF4/FMR2 family, member 2	0.082
KIAA1377	KIAA1377	0.082
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.082
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.082
CDK5	cyclin-dependent kinase 5	0.081	Mouse
PRDM13	PR domain containing 13	0.081
BIRC6	baculoviral IAP repeat containing 6	0.081
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.081
GJD2	gap junction protein, delta 2, 36kDa	0.081
TBX5	T-box 5	0.080
IHH	Indian hedgehog	0.080
ADARB2	adenosine deaminase, RNA-specific, B2	0.080
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.080
WNT10B	wingless-type MMTV integration site family, member 10B	0.080
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.080
AATK	apoptosis-associated tyrosine kinase	0.080
BHLHE23	basic helix-loop-helix family, member e23	0.080
HCRTR1	hypocretin (orexin) receptor 1	0.080
TP53BP1	tumor protein p53 binding protein 1	0.080
AMELX	amelogenin, X-linked	0.079
PCDH9	protocadherin 9	0.079
TLX3	T-cell leukemia homeobox 3	0.079
CCND1	cyclin D1	0.079
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.079
NEUROG2	neurogenin 2	0.079	Human
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.079	Zebrafish
TMEM59L	transmembrane protein 59-like	0.079
TIGD3	tigger transposable element derived 3	0.079
FAM123A	family with sequence similarity 123A	0.079
GLI2	GLI family zinc finger 2	0.079	Mouse
SHOX2	short stature homeobox 2	0.078
GIGYF2	GRB10 interacting GYF protein 2	0.078
FZD10	frizzled homolog 10 (Drosophila)	0.078
SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.078
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.078
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.078
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.078
WNT11	wingless-type MMTV integration site family, member 11	0.078
LMX1B	LIM homeobox transcription factor 1, beta	0.078	Zebrafish Mouse
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.078	Zebrafish
PGR	progesterone receptor	0.077
HOXB3	homeobox B3	0.077	Mouse
CNTFR	ciliary neurotrophic factor receptor	0.077
AMOTL2	angiomotin like 2	0.077
PCDH8	protocadherin 8	0.077
CALB2	calbindin 2	0.077
BSN	bassoon (presynaptic cytomatrix protein)	0.077
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.076
CBX4	chromobox homolog 4	0.076
RANBP2	RAN binding protein 2	0.076
MARK4	MAP/microtubule affinity-regulating kinase 4	0.076
SLC32A1	solute carrier family 32 (GABA vesicular transporter), member 1	0.076
DIO3	deiodinase, iodothyronine, type III	0.076
ITGA6	integrin, alpha 6	0.076
ASB12	ankyrin repeat and SOCS box containing 12	0.075
BNC1	basonuclin 1	0.075
F11R	F11 receptor	0.075
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.075
BAI1	brain-specific angiogenesis inhibitor 1	0.075
THBS1	thrombospondin 1	0.075
DLX4	distal-less homeobox 4	0.075
GGN	gametogenetin	0.075
FGF17	fibroblast growth factor 17	0.075
GPRIN2	G protein regulated inducer of neurite outgrowth 2	0.075
MMD2	monocyte to macrophage differentiation-associated 2	0.075
GLP1R	glucagon-like peptide 1 receptor	0.075
DAB1	disabled homolog 1 (Drosophila)	0.075	Mouse
TM9SF1	transmembrane 9 superfamily member 1	0.074
TBX2	T-box 2	0.074
FOXF1	forkhead box F1	0.074
HOXA2	homeobox A2	0.074	Mouse
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.074
COL4A6	collagen, type IV, alpha 6	0.074
PDIA6	protein disulfide isomerase family A, member 6	0.074
FGF5	fibroblast growth factor 5	0.074
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.074
NOS1	nitric oxide synthase 1 (neuronal)	0.074
BARHL1	BarH-like homeobox 1	0.073
WNT7A	wingless-type MMTV integration site family, member 7A	0.073
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.073
PCDHA2	protocadherin alpha 2	0.073
RLIM	ring finger protein, LIM domain interacting	0.073
HOXB13	homeobox B13	0.073
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.073
SOX3	SRY (sex determining region Y)-box 3	0.073
GPR161	G protein-coupled receptor 161	0.073
CA10	carbonic anhydrase X	0.073
ECEL1	endothelin converting enzyme-like 1	0.073
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.073
MEF2C	myocyte enhancer factor 2C	0.073
NOV	nephroblastoma overexpressed gene	0.073
DMXL1	Dmx-like 1	0.073
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.073
CDK6	cyclin-dependent kinase 6	0.073
PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide	0.072
PRRX2	paired related homeobox 2	0.072
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.072
NAP1L5	nucleosome assembly protein 1-like 5	0.072
IRX5	iroquois homeobox 5	0.072
RELN	reelin	0.072
PRKCA	protein kinase C, alpha	0.072
GATA6	GATA binding protein 6	0.072
CBX2	chromobox homolog 2	0.072
BCL2L1	BCL2-like 1	0.071
NPAS4	neuronal PAS domain protein 4	0.071
ALX1	ALX homeobox 1	0.071
TBC1D14	TBC1 domain family, member 14	0.071
CBX7	chromobox homolog 7	0.071
PDZD2	PDZ domain containing 2	0.071
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.071
STAT5A	signal transducer and activator of transcription 5A	0.071
CELF4	CUGBP, Elav-like family member 4	0.071
HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	0.071
PRDM8	PR domain containing 8	0.071
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.071
USP45	ubiquitin specific peptidase 45	0.071
SLC17A6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.070
KCNC2	potassium voltage-gated channel, Shaw-related subfamily, member 2	0.070
PSMG2	proteasome (prosome, macropain) assembly chaperone 2	0.070
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.070
INSM2	insulinoma-associated 2	0.070
ALX4	ALX homeobox 4	0.070
DCC	deleted in colorectal carcinoma	0.070
BRAP	BRCA1 associated protein	0.070
SGSM2	small G protein signaling modulator 2	0.070
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.070
RIPPLY2	ripply2 homolog (zebrafish)	0.070
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.070
ESR2	estrogen receptor 2 (ER beta)	0.070	Rat
GDF7	growth differentiation factor 7	0.070
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.069
HOXC12	homeobox C12	0.069
NOL4	nucleolar protein 4	0.069
OLIG3	oligodendrocyte transcription factor 3	0.069
PHF17	PHD finger protein 17	0.069
SEZ6L	seizure related 6 homolog (mouse)-like	0.069	Mouse
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.069
AJAP1	adherens junctions associated protein 1	0.069
KIF1A	kinesin family member 1A	0.068
ALAS1	aminolevulinate, delta-, synthase 1	0.068
PKNOX2	PBX/knotted 1 homeobox 2	0.068
ARX	aristaless related homeobox	0.068
ZNF536	zinc finger protein 536	0.068
SEC24A	SEC24 family, member A (S. cerevisiae)	0.068
RBMS3	RNA binding motif, single stranded interacting protein 3	0.068
KCNK3	potassium channel, subfamily K, member 3	0.068
MSI1	musashi homolog 1 (Drosophila)	0.068
FLNB	filamin B, beta	0.068
NHLH1	nescient helix loop helix 1	0.068	Human
GAP43	growth associated protein 43	0.068
HOXD11	homeobox D11	0.068
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.068
PDE10A	phosphodiesterase 10A	0.068
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.068	Mouse
TNS4	tensin 4	0.068
SLIT2	slit homolog 2 (Drosophila)	0.067
SETDB1	SET domain, bifurcated 1	0.067
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.067
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.067
FOXL2	forkhead box L2	0.067
WDFY3	WD repeat and FYVE domain containing 3	0.067
SIX2	SIX homeobox 2	0.067
PSAT1	phosphoserine aminotransferase 1	0.067
FGF4	fibroblast growth factor 4	0.067
HES7	hairy and enhancer of split 7 (Drosophila)	0.066
MUC1	mucin 1, cell surface associated	0.066
EYA1	eyes absent homolog 1 (Drosophila)	0.066
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.066
VAV2	vav 2 guanine nucleotide exchange factor	0.066
PSD	pleckstrin and Sec7 domain containing	0.066
DLG5	discs, large homolog 5 (Drosophila)	0.066
JAM3	junctional adhesion molecule 3	0.066
ZMYND8	zinc finger, MYND-type containing 8	0.066
DPYSL5	dihydropyrimidinase-like 5	0.066
MAPRE3	microtubule-associated protein, RP/EB family, member 3	0.066
PCDH17	protocadherin 17	0.066
TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.065
DBN1	drebrin 1	0.065
HOXD10	homeobox D10	0.065
AQP5	aquaporin 5	0.065
COL11A1	collagen, type XI, alpha 1	0.065
TADA3	transcriptional adaptor 3	0.065
FABP7	fatty acid binding protein 7, brain	0.065
FAM20C	family with sequence similarity 20, member C	0.065
CHGA	chromogranin A (parathyroid secretory protein 1)	0.065
SF1	splicing factor 1	0.065
PRKCG	protein kinase C, gamma	0.065
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.065
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.065
SIN3B	SIN3 homolog B, transcription regulator (yeast)	0.064
GPC4	glypican 4	0.064
CLTC	clathrin, heavy chain (Hc)	0.064
RORB	RAR-related orphan receptor B	0.064
KIAA1370	KIAA1370	0.064
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.064
PHOX2B	paired-like homeobox 2b	0.064	Mouse
RARG	retinoic acid receptor, gamma	0.064
NR2C1	nuclear receptor subfamily 2, group C, member 1	0.064
UNC5C	unc-5 homolog C (C. elegans)	0.064
BTRC	beta-transducin repeat containing	0.064
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.064
VAX1	ventral anterior homeobox 1	0.064
NCKAP1	NCK-associated protein 1	0.063
BHLHE22	basic helix-loop-helix family, member e22	0.063
HES1	hairy and enhancer of split 1, (Drosophila)	0.063	Mouse
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.063
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.063
GRM3	glutamate receptor, metabotropic 3	0.063
NPAS3	neuronal PAS domain protein 3	0.063
MED12	mediator complex subunit 12	0.063
GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.063
LAMA4	laminin, alpha 4	0.063
SMO	smoothened homolog (Drosophila)	0.063	Zebrafish
HAS2	hyaluronan synthase 2	0.063	Zebrafish
MED14	mediator complex subunit 14	0.063
RIMS4	regulating synaptic membrane exocytosis 4	0.063
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.063
DRD4	dopamine receptor D4	0.063
GHR	growth hormone receptor	0.062
KLF12	Kruppel-like factor 12	0.062
NYNRIN	NYN domain and retroviral integrase containing	0.062
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.062
CTBP1	C-terminal binding protein 1	0.062
TCF15	transcription factor 15 (basic helix-loop-helix)	0.062	Human
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.062
OSBP	oxysterol binding protein	0.062
NXPH1	neurexophilin 1	0.062
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.062
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.062
TF	transferrin	0.062
NUDCD1	NudC domain containing 1	0.062
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.062
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.062
GDF6	growth differentiation factor 6	0.062
SLITRK5	SLIT and NTRK-like family, member 5	0.061
CACNB4	calcium channel, voltage-dependent, beta 4 subunit	0.061
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.061
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.061
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.061
WSCD1	WSC domain containing 1	0.061
OTOP3	otopetrin 3	0.061
GSX2	GS homeobox 2	0.061	Mouse
NTF3	neurotrophin 3	0.061
RB1CC1	RB1-inducible coiled-coil 1	0.061
ASXL1	additional sex combs like 1 (Drosophila)	0.061
ZNF579	zinc finger protein 579	0.061
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.060
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.060
RPN1	ribophorin I	0.060
GPR88	G protein-coupled receptor 88	0.060
SRPR	signal recognition particle receptor (docking protein)	0.060
MAML1	mastermind-like 1 (Drosophila)	0.060
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.060
TGFB2	transforming growth factor, beta 2	0.060	Rat
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.060
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.060
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.059
QPRT	quinolinate phosphoribosyltransferase	0.059
OLIG1	oligodendrocyte transcription factor 1	0.059
HOXA7	homeobox A7	0.059
RIMBP2	RIMS binding protein 2	0.059
BMPR1A	bone morphogenetic protein receptor, type IA	0.059
SOCS5	suppressor of cytokine signaling 5	0.059
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.059
NRXN3	neurexin 3	0.059
SCRIB	scribbled homolog (Drosophila)	0.059	Mouse
EBF3	early B-cell factor 3	0.059
MAPK8	mitogen-activated protein kinase 8	0.059
VSX1	visual system homeobox 1	0.059
DSCAM	Down syndrome cell adhesion molecule	0.058
HOXD8	homeobox D8	0.058
T	T, brachyury homolog (mouse)	0.058