IMP: Integrative Multi-species Prediction

Homo sapiens

13 genes annotated in human

meiotic cell cycle

Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "meiotic cell cycle"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "meiotic cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.962	Yeast Mouse Worm Fly
RPA1	replication protein A1, 70kDa	0.941	Yeast Mouse
BRCA1	breast cancer 1, early onset	0.930
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.863
TP53	tumor protein p53	0.653	Worm Fly
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.502
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.492
MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	0.429	Yeast
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.406
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.400	Yeast Mouse Fly
SKP1	S-phase kinase-associated protein 1	0.390	Worm
RAD21	RAD21 homolog (S. pombe)	0.385	Worm
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.374	Yeast Worm
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.337	Worm
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.336	Worm
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.326
SMC1A	structural maintenance of chromosomes 1A	0.303	Mouse
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.301
BLM	Bloom syndrome, RecQ helicase-like	0.298	Worm Fly
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.287	Worm
CDK2	cyclin-dependent kinase 2	0.283	Yeast
BRCA2	breast cancer 2, early onset	0.278	Mouse
SMC3	structural maintenance of chromosomes 3	0.274
SF1	splicing factor 1	0.229	Worm
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.226
RNPS1	RNA binding protein S1, serine-rich domain	0.223	Worm
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.217
CDK1	cyclin-dependent kinase 1	0.203	Yeast Worm Fly
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.193
SMC2	structural maintenance of chromosomes 2	0.185	Yeast Mouse
SRPK1	SRSF protein kinase 1	0.173	Worm Fly
CCNA2	cyclin A2	0.163
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.158
CCNE1	cyclin E1	0.154	Worm
CCNB1	cyclin B1	0.154	Yeast
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.151
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.150
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.140
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.135	Yeast Worm
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.132
MCM10	minichromosome maintenance complex component 10	0.130	Fly
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.130	Worm
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.121	Worm
SRSF1	serine/arginine-rich splicing factor 1	0.117
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.116
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.115	Worm
PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.113
SKP2	S-phase kinase-associated protein 2 (p45)	0.104
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.101	Worm
ATXN1	ataxin 1	0.100
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.097
NCAPH	non-SMC condensin I complex, subunit H	0.097
FBXO5	F-box protein 5	0.095	Mouse
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.095	Worm
PLK1	polo-like kinase 1	0.095	Yeast Rat Worm Fly
SNX6	sorting nexin 6	0.091
MSH6	mutS homolog 6 (E. coli)	0.090	Yeast
RB1	retinoblastoma 1	0.088
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.086
MCM6	minichromosome maintenance complex component 6	0.085
DAZ1	deleted in azoospermia 1	0.084	Human
PCNA	proliferating cell nuclear antigen	0.080
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.080
MSH5	mutS homolog 5 (E. coli)	0.078	Yeast Mouse Worm
CHERP	calcium homeostasis endoplasmic reticulum protein	0.077
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.074
RFC1	replication factor C (activator 1) 1, 145kDa	0.073
RBM10	RNA binding motif protein 10	0.070
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.070	Worm
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	0.069
CAND1	cullin-associated and neddylation-dissociated 1	0.069
WBP4	WW domain binding protein 4 (formin binding protein 21)	0.066
SNRPG	small nuclear ribonucleoprotein polypeptide G	0.065
NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.065
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.063
FLNA	filamin A, alpha	0.063	Worm
MCM3	minichromosome maintenance complex component 3	0.061
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.060
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.060
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.059
SNRPB2	small nuclear ribonucleoprotein polypeptide B	0.059	Worm
EXO1	exonuclease 1	0.059	Yeast
SNRPE	small nuclear ribonucleoprotein polypeptide E	0.058
SNW1	SNW domain containing 1	0.056
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.056
POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	0.056	Yeast
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.056
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.054
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.053
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.051
TCP1	t-complex 1	0.051
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.050
SF3B4	splicing factor 3b, subunit 4, 49kDa	0.050
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	0.048
PABPC1	poly(A) binding protein, cytoplasmic 1	0.048
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.048
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.047
USP1	ubiquitin specific peptidase 1	0.046
TOPBP1	topoisomerase (DNA) II binding protein 1	0.046
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.046
GPKOW	G patch domain and KOW motifs	0.044
CNOT8	CCR4-NOT transcription complex, subunit 8	0.044	Worm
CTCF	CCCTC-binding factor (zinc finger protein)	0.043
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.043
RAD50	RAD50 homolog (S. cerevisiae)	0.043	Worm
LSM6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.042
SMAD2	SMAD family member 2	0.041	Worm
ERCC6L	excision repair cross-complementing rodent repair deficiency, complementation group 6-like	0.041
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.040
PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)	0.039
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.038
RBL1	retinoblastoma-like 1 (p107)	0.037
MCM7	minichromosome maintenance complex component 7	0.037
MCMBP	minichromosome maintenance complex binding protein	0.037
PRC1	protein regulator of cytokinesis 1	0.036
RPA3	replication protein A3, 14kDa	0.036
CDC45	cell division cycle 45 homolog (S. cerevisiae)	0.035
PLK4	polo-like kinase 4	0.034	Fly
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.033
RFC4	replication factor C (activator 1) 4, 37kDa	0.033
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.032	Yeast Worm
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.032
CKAP5	cytoskeleton associated protein 5	0.032	Worm Fly
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.032	Mouse
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.032
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.032
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.031
NBN	nibrin	0.031
WRN	Werner syndrome, RecQ helicase-like	0.031
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.031
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.031	Worm
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.031
SNRPA	small nuclear ribonucleoprotein polypeptide A	0.031	Worm
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.030
CUL1	cullin 1	0.030
MAPK1	mitogen-activated protein kinase 1	0.030	Worm
TCERG1	transcription elongation regulator 1	0.030	Worm
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.030	Yeast Mouse Worm
RFC3	replication factor C (activator 1) 3, 38kDa	0.030
SCHIP1	schwannomin interacting protein 1	0.029
RFC2	replication factor C (activator 1) 2, 40kDa	0.029
H2AFX	H2A histone family, member X	0.029
CLSPN	claspin	0.029
CENPF	centromere protein F, 350/400kDa (mitosin)	0.029
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.028
BARD1	BRCA1 associated RING domain 1	0.028
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.027
AURKA	aurora kinase A	0.027	Yeast Mouse Worm
NCAPG2	non-SMC condensin II complex, subunit G2	0.027
CBX3	chromobox homolog 3	0.027
CBX1	chromobox homolog 1	0.026
RAD51AP1	RAD51 associated protein 1	0.026
HSPB1	heat shock 27kDa protein 1	0.026
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.026	Fly
SRSF10	serine/arginine-rich splicing factor 10	0.026
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.026	Worm
POMP	proteasome maturation protein	0.026
DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	0.026	Worm
THOC4	THO complex 4	0.026
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.025	Worm
NIPBL	Nipped-B homolog (Drosophila)	0.025
PUF60	poly-U binding splicing factor 60KDa	0.025	Worm
RAD54B	RAD54 homolog B (S. cerevisiae)	0.025	Yeast
FOXM1	forkhead box M1	0.024
HAT1	histone acetyltransferase 1	0.024
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.023	Yeast Worm
KIAA1524	KIAA1524	0.023
CENPE	centromere protein E, 312kDa	0.022
SNRPA1	small nuclear ribonucleoprotein polypeptide A'	0.022
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.022
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.022
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.021
LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.021
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.021	Worm
CSNK2B	casein kinase 2, beta polypeptide	0.021
KIF23	kinesin family member 23	0.021	Worm Fly
SMC4	structural maintenance of chromosomes 4	0.020	Mouse
MCM2	minichromosome maintenance complex component 2	0.020
SMAD5	SMAD family member 5	0.020	Worm
POLQ	polymerase (DNA directed), theta	0.020
SART1	squamous cell carcinoma antigen recognized by T cells	0.020	Worm
DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.020	Worm
CREBBP	CREB binding protein	0.020
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.020
WWOX	WW domain containing oxidoreductase	0.020
FBXW11	F-box and WD repeat domain containing 11	0.019
MSH3	mutS homolog 3 (E. coli)	0.019	Yeast
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.019	Worm
MSH4	mutS homolog 4 (E. coli)	0.019	Yeast
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.019
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.019	Worm
CCT2	chaperonin containing TCP1, subunit 2 (beta)	0.019
TUBGCP3	tubulin, gamma complex associated protein 3	0.019	Fly
FEN1	flap structure-specific endonuclease 1	0.019
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.019
DAXX	death-domain associated protein	0.018
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.018	Worm Fly
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.018
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.018
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.018
TK1	thymidine kinase 1, soluble	0.018
CHUK	conserved helix-loop-helix ubiquitous kinase	0.018
CTNNBL1	catenin, beta like 1	0.018
RBBP8	retinoblastoma binding protein 8	0.018
STMN1	stathmin 1	0.018
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.018
LMNA	lamin A/C	0.017	Worm
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.017
SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	0.017
PPP4C	protein phosphatase 4, catalytic subunit	0.017	Yeast Worm
DYNLL1	dynein, light chain, LC8-type 1	0.017	Worm
SF3A3	splicing factor 3a, subunit 3, 60kDa	0.017	Worm
RBBP7	retinoblastoma binding protein 7	0.017
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.017
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.017
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.017
TRA2B	transformer 2 beta homolog (Drosophila)	0.016
DEPDC1	DEP domain containing 1	0.016
UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	0.016
BAG3	BCL2-associated athanogene 3	0.016
RBM39	RNA binding motif protein 39	0.016
MATR3	matrin 3	0.016
TACC3	transforming, acidic coiled-coil containing protein 3	0.015
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.015	Mouse
BUD13	BUD13 homolog (S. cerevisiae)	0.015
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.015
CCND3	cyclin D3	0.015
SRPK2	SRSF protein kinase 2	0.015	Worm Fly
STRN3	striatin, calmodulin binding protein 3	0.015
CCNB2	cyclin B2	0.015	Yeast
CAPRIN1	cell cycle associated protein 1	0.015
NKAP	NFKB activating protein	0.015
CCND1	cyclin D1	0.015
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.015
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.015	Worm
ISY1	ISY1 splicing factor homolog (S. cerevisiae)	0.014
CTTNBP2NL	CTTNBP2 N-terminal like	0.014
ECT2	epithelial cell transforming sequence 2 oncogene	0.014	Fly
DAZL	deleted in azoospermia-like	0.014	Human Mouse
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.014
CUL3	cullin 3	0.014
SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	0.014
NUP107	nucleoporin 107kDa	0.014
CKS2	CDC28 protein kinase regulatory subunit 2	0.014	Mouse Worm Fly
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.014
HLTF	helicase-like transcription factor	0.014
NAA38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.014
PALB2	partner and localizer of BRCA2	0.014
AURKB	aurora kinase B	0.013
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.013
GTSE1	G-2 and S-phase expressed 1	0.013
HIST1H3D	histone cluster 1, H3d	0.013
APC	adenomatous polyposis coli	0.013
POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	0.013
COPE	coatomer protein complex, subunit epsilon	0.013
HIST1H4B	histone cluster 1, H4b	0.013	Yeast
USP39	ubiquitin specific peptidase 39	0.013
SRSF3	serine/arginine-rich splicing factor 3	0.013
IPO7	importin 7	0.013
RAD1	RAD1 homolog (S. pombe)	0.013
PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.013	Worm
RFC5	replication factor C (activator 1) 5, 36.5kDa	0.013
DEK	DEK oncogene	0.013
MYL12B	myosin, light chain 12B, regulatory	0.013	Worm
MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	0.012	Yeast Zebrafish Mouse
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.012
STIL	SCL/TAL1 interrupting locus	0.012
NUP205	nucleoporin 205kDa	0.012
SF3B14	splicing factor 3B, 14 kDa subunit	0.012
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.012
CNOT6	CCR4-NOT transcription complex, subunit 6	0.012
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.012	Yeast Mouse Worm
DHX38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	0.012
RBM7	RNA binding motif protein 7	0.012
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.012
ADNP	activity-dependent neuroprotector homeobox	0.012
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.012
SAP30BP	SAP30 binding protein	0.012
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.012
HIST1H4A	histone cluster 1, H4a	0.012	Yeast
RHOA	ras homolog gene family, member A	0.012
CCDC6	coiled-coil domain containing 6	0.012
KIF18A	kinesin family member 18A	0.012	Fly
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.011	Yeast
DAZAP2	DAZ associated protein 2	0.011
PDCD10	programmed cell death 10	0.011
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.011
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.011
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.011
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.011
KIF4A	kinesin family member 4A	0.011	Fly
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.011	Worm Fly
AKT1S1	AKT1 substrate 1 (proline-rich)	0.011
CDKN3	cyclin-dependent kinase inhibitor 3	0.011
LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.011	Worm
SUB1	SUB1 homolog (S. cerevisiae)	0.011
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.011
RBM4	RNA binding motif protein 4	0.011
WDR83	WD repeat domain 83	0.011
NCOR1	nuclear receptor corepressor 1	0.011
HIST1H3B	histone cluster 1, H3b	0.011	Yeast
TUBB	tubulin, beta	0.010
MDC1	mediator of DNA-damage checkpoint 1	0.010
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.010
RAN	RAN, member RAS oncogene family	0.010
MARK2	MAP/microtubule affinity-regulating kinase 2	0.010
RANBP2	RAN binding protein 2	0.010
ETF1	eukaryotic translation termination factor 1	0.010
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.010
MED31	mediator complex subunit 31	0.010
HIST1H2AE	histone cluster 1, H2ae	0.010
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.010