IMP: Integrative Multi-species Prediction

Homo sapiens

39 genes annotated in human

neuron apoptotic process

Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neuron apoptotic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "neuron apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2	B-cell CLL/lymphoma 2	0.998
ESR1	estrogen receptor 1	0.996	Rat
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.944	Mouse Rat
EP300	E1A binding protein p300	0.925
EGFR	epidermal growth factor receptor	0.912	Human
CREBBP	CREB binding protein	0.898
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.888
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.882
VEGFA	vascular endothelial growth factor A	0.794	Human Mouse
BRCA1	breast cancer 1, early onset	0.780
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.758
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.754	Mouse
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.714
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.714
MAPK8	mitogen-activated protein kinase 8	0.710
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.679	Rat
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.661
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.639
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.629
BID	BH3 interacting domain death agonist	0.604
APP	amyloid beta (A4) precursor protein	0.591
BCL2L1	BCL2-like 1	0.569	Human Mouse
DLG4	discs, large homolog 4 (Drosophila)	0.558
FAS	Fas (TNF receptor superfamily, member 6)	0.515	Mouse
CAV1	caveolin 1, caveolae protein, 22kDa	0.499
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.472
BAD	BCL2-associated agonist of cell death	0.425
BAX	BCL2-associated X protein	0.415
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.344
XIAP	X-linked inhibitor of apoptosis	0.330	Mouse Rat
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.328
HSPA8	heat shock 70kDa protein 8	0.302
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.293
IL8	interleukin 8	0.275
SMAD3	SMAD family member 3	0.275
VHL	von Hippel-Lindau tumor suppressor	0.275
IGF1R	insulin-like growth factor 1 receptor	0.272
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.272
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.269
SOCS3	suppressor of cytokine signaling 3	0.260
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.257
LAT	linker for activation of T cells	0.251
RPL18A	ribosomal protein L18a	0.240
AR	androgen receptor	0.237
GRB2	growth factor receptor-bound protein 2	0.231
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.230
EPAS1	endothelial PAS domain protein 1	0.227	Human Zebrafish
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.224
PDZD11	PDZ domain containing 11	0.209
CCR5	chemokine (C-C motif) receptor 5	0.207
NBN	nibrin	0.201
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.200
HDAC4	histone deacetylase 4	0.192	Rat
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.188
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.183
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.174	Mouse Rat
TP53	tumor protein p53	0.171	Zebrafish Mouse
RPS6	ribosomal protein S6	0.159
HIPK2	homeodomain interacting protein kinase 2	0.159	Mouse
CFLAR	CASP8 and FADD-like apoptosis regulator	0.159
SP1	Sp1 transcription factor	0.153
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.151
CBX5	chromobox homolog 5	0.149
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.148
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.143
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.139
NRP1	neuropilin 1	0.138	Mouse
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.137
MAPT	microtubule-associated protein tau	0.135
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.130
CREB1	cAMP responsive element binding protein 1	0.124
RUNX1	runt-related transcription factor 1	0.119
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.118	Human
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.106
SFPQ	splicing factor proline/glutamine-rich	0.104	Human
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.103
TP53BP2	tumor protein p53 binding protein, 2	0.103
BECN1	beclin 1, autophagy related	0.101
EGLN1	egl nine homolog 1 (C. elegans)	0.097	Human
TGFB1	transforming growth factor, beta 1	0.093	Human
AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	0.091	Human
ZNF746	zinc finger protein 746	0.090
KAT2B	K(lysine) acetyltransferase 2B	0.089
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.087
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.084	Mouse
GAS6	growth arrest-specific 6	0.082
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.081
FKBP8	FK506 binding protein 8, 38kDa	0.081
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.075
NOXA1	NADPH oxidase activator 1	0.075
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.075
SMAD2	SMAD family member 2	0.075
STAT5A	signal transducer and activator of transcription 5A	0.074
PPP5C	protein phosphatase 5, catalytic subunit	0.073
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.072
AGAP5	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5	0.072	Human
ESRRG	estrogen-related receptor gamma	0.072
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.071	Mouse
PPARG	peroxisome proliferator-activated receptor gamma	0.071
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.069
APLF	aprataxin and PNKP like factor	0.069
SIRT1	sirtuin 1	0.069
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.068
SOS1	son of sevenless homolog 1 (Drosophila)	0.067
TEK	TEK tyrosine kinase, endothelial	0.067
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.065
PKM2	pyruvate kinase, muscle	0.065
NGF	nerve growth factor (beta polypeptide)	0.064	Mouse
CD177	CD177 molecule	0.064
LIG4	ligase IV, DNA, ATP-dependent	0.064	Mouse
LRIF1	ligand dependent nuclear receptor interacting factor 1	0.060
BAK1	BCL2-antagonist/killer 1	0.059	Human
SFN	stratifin	0.057
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.057
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.056
DCAF7	DDB1 and CUL4 associated factor 7	0.055
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.055
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.054
FYN	FYN oncogene related to SRC, FGR, YES	0.054	Rat
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.053
MEF2A	myocyte enhancer factor 2A	0.052
SMN1	survival of motor neuron 1, telomeric	0.052
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.052
CCL8	chemokine (C-C motif) ligand 8	0.050	Human
TRIB3	tribbles homolog 3 (Drosophila)	0.050
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.048
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.047
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.047	Rat
VDAC2	voltage-dependent anion channel 2	0.047
NCOA2	nuclear receptor coactivator 2	0.046
SOD1	superoxide dismutase 1, soluble	0.045
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.045
PXN	paxillin	0.045
PPID	peptidylprolyl isomerase D	0.045
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.044
FBXO7	F-box protein 7	0.044
CCNE1	cyclin E1	0.044
IRS1	insulin receptor substrate 1	0.043
DRD2	dopamine receptor D2	0.043
RPS5	ribosomal protein S5	0.043
BIRC3	baculoviral IAP repeat containing 3	0.042
IL1B	interleukin 1, beta	0.042
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.042
TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	0.042
FANCD2	Fanconi anemia, complementation group D2	0.041
LDLR	low density lipoprotein receptor	0.041
HDAC2	histone deacetylase 2	0.040
MAPK6	mitogen-activated protein kinase 6	0.040
EGR3	early growth response 3	0.040
ABI1	abl-interactor 1	0.040
ENG	endoglin	0.039
NCOA1	nuclear receptor coactivator 1	0.039
RPL7A	ribosomal protein L7a	0.039
DDIT3	DNA-damage-inducible transcript 3	0.038	Mouse
IDE	insulin-degrading enzyme	0.037
DCTN1	dynactin 1	0.037
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.037
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.037
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.037
EGR1	early growth response 1	0.036	Rat
CCL4	chemokine (C-C motif) ligand 4	0.036	Human
HSPH1	heat shock 105kDa/110kDa protein 1	0.036
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.036
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.035
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.035
BIRC2	baculoviral IAP repeat containing 2	0.035
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.035
CABLES1	Cdk5 and Abl enzyme substrate 1	0.035
IL6	interleukin 6 (interferon, beta 2)	0.034
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.034
FLNB	filamin B, beta	0.034
RPL6	ribosomal protein L6	0.034
SIAH1	seven in absentia homolog 1 (Drosophila)	0.034
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.034
WWOX	WW domain containing oxidoreductase	0.034
RPL17	ribosomal protein L17	0.033
ATN1	atrophin 1	0.033
FASLG	Fas ligand (TNF superfamily, member 6)	0.033
APAF1	apoptotic peptidase activating factor 1	0.033	Mouse
KRT5	keratin 5	0.033
HSPA1B	heat shock 70kDa protein 1B	0.033
RAD50	RAD50 homolog (S. cerevisiae)	0.032
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.032
RPS2	ribosomal protein S2	0.032
EGR2	early growth response 2	0.032
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.032
BCOR	BCL6 corepressor	0.031
JUN	jun proto-oncogene	0.031	Mouse Rat
CCL13	chemokine (C-C motif) ligand 13	0.031	Human
TRADD	TNFRSF1A-associated via death domain	0.031
LRRK2	leucine-rich repeat kinase 2	0.031
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.031
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.031
SH3RF1	SH3 domain containing ring finger 1	0.030
TCF4	transcription factor 4	0.030
TGFBR1	transforming growth factor, beta receptor 1	0.030
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.030
RGS2	regulator of G-protein signaling 2, 24kDa	0.030
GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.030
YY1	YY1 transcription factor	0.030
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.029	Human Mouse
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.029
RIN1	Ras and Rab interactor 1	0.029
METAP1	methionyl aminopeptidase 1	0.029
SKP1	S-phase kinase-associated protein 1	0.029
NAMPT	nicotinamide phosphoribosyltransferase	0.029
TNF	tumor necrosis factor	0.029
RPSA	ribosomal protein SA	0.028
CCL2	chemokine (C-C motif) ligand 2	0.028
CBX1	chromobox homolog 1	0.028
MAPK9	mitogen-activated protein kinase 9	0.028
S100B	S100 calcium binding protein B	0.027
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.027
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.027
PGK1	phosphoglycerate kinase 1	0.027
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.027
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.027
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.027	Mouse
PDGFC	platelet derived growth factor C	0.027
EIF1AX	eukaryotic translation initiation factor 1A, X-linked	0.026
MEF2C	myocyte enhancer factor 2C	0.026	Mouse
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.026
APLP1	amyloid beta (A4) precursor-like protein 1	0.026
BTG1	B-cell translocation gene 1, anti-proliferative	0.026
RPS16	ribosomal protein S16	0.026
PDE4DIP	phosphodiesterase 4D interacting protein	0.026
RGS1	regulator of G-protein signaling 1	0.026
RPL36	ribosomal protein L36	0.025
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.025
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.025	Mouse
CDK4	cyclin-dependent kinase 4	0.025
BCL6	B-cell CLL/lymphoma 6	0.025
PTEN	phosphatase and tensin homolog	0.025
BBC3	BCL2 binding component 3	0.025
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.025
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.025
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.025
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.024
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.024
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.024
DBP	D site of albumin promoter (albumin D-box) binding protein	0.024
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.024
PINK1	PTEN induced putative kinase 1	0.024
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.024
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.024	Rat
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.024
INCENP	inner centromere protein antigens 135/155kDa	0.024
RBBP4	retinoblastoma binding protein 4	0.023
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.023
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.023
BIK	BCL2-interacting killer (apoptosis-inducing)	0.023
FADD	Fas (TNFRSF6)-associated via death domain	0.023	Mouse
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.023
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.023
BAG1	BCL2-associated athanogene	0.023	Mouse
ATF2	activating transcription factor 2	0.023
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.022	Mouse
NTF4	neurotrophin 4	0.022
MSH6	mutS homolog 6 (E. coli)	0.022
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.022
SKA3	spindle and kinetochore associated complex subunit 3	0.022
NCF4	neutrophil cytosolic factor 4, 40kDa	0.022
HIPK3	homeodomain interacting protein kinase 3	0.022
NCF1	neutrophil cytosolic factor 1	0.022
IQGAP1	IQ motif containing GTPase activating protein 1	0.022
TCEAL5	transcription elongation factor A (SII)-like 5	0.021
CXCL9	chemokine (C-X-C motif) ligand 9	0.021
LTBP4	latent transforming growth factor beta binding protein 4	0.021
CDK6	cyclin-dependent kinase 6	0.021
RPL18	ribosomal protein L18	0.021
LRDD	leucine-rich repeats and death domain containing	0.021
RPL11	ribosomal protein L11	0.021
TUBB2B	tubulin, beta 2B	0.021
PGF	placental growth factor	0.021	Human
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.021
MYLK2	myosin light chain kinase 2	0.021
MATK	megakaryocyte-associated tyrosine kinase	0.021
JAK2	Janus kinase 2	0.020	Rat
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.020
ARHGAP1	Rho GTPase activating protein 1	0.020
XPO1	exportin 1 (CRM1 homolog, yeast)	0.020
CD83	CD83 molecule	0.020
CHD3	chromodomain helicase DNA binding protein 3	0.020
RPL7	ribosomal protein L7	0.020
GFI1B	growth factor independent 1B transcription repressor	0.020
RPL10A	ribosomal protein L10a	0.020
RHOG	ras homolog gene family, member G (rho G)	0.020
LPL	lipoprotein lipase	0.020
RPL21	ribosomal protein L21	0.020
SQSTM1	sequestosome 1	0.020
SKA2	spindle and kinetochore associated complex subunit 2	0.020
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.020
JAK1	Janus kinase 1	0.020
RPS3A	ribosomal protein S3A	0.019
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.019
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.019
INSR	insulin receptor	0.019
DPP4	dipeptidyl-peptidase 4	0.019
HDAC9	histone deacetylase 9	0.019
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.019
PFN1	profilin 1	0.019
WBP2	WW domain binding protein 2	0.019
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.019
EED	embryonic ectoderm development	0.019
NOTCH1	notch 1	0.019
GHR	growth hormone receptor	0.019
CBX3	chromobox homolog 3	0.018
EGLN3	egl nine homolog 3 (C. elegans)	0.018	Human
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.018
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.018
XRCC1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.018
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.018
CAV2	caveolin 2	0.018
COL2A1	collagen, type II, alpha 1	0.018
CUL1	cullin 1	0.018
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.018	Rat
SOCS2	suppressor of cytokine signaling 2	0.018
NMI	N-myc (and STAT) interactor	0.018
JAK3	Janus kinase 3	0.018
VCAM1	vascular cell adhesion molecule 1	0.018
RPLP2	ribosomal protein, large, P2	0.017
HNF4A	hepatocyte nuclear factor 4, alpha	0.017
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.017	Human
NCOR1	nuclear receptor corepressor 1	0.017
RABGGTB	Rab geranylgeranyltransferase, beta subunit	0.017
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.017	Mouse
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.017
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.017
RPL8	ribosomal protein L8	0.017
RNR2	l-rRNA	0.017
IFNGR1	interferon gamma receptor 1	0.017
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.017
PRMT2	protein arginine methyltransferase 2	0.017
FHL2	four and a half LIM domains 2	0.017
PTMA	prothymosin, alpha	0.017
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.017	Mouse
MTA1	metastasis associated 1	0.016
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	0.016
SPRR2A	small proline-rich protein 2A	0.016
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.016	Mouse
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.016
PPA1	pyrophosphatase (inorganic) 1	0.016
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.016	Human
ARNT	aryl hydrocarbon receptor nuclear translocator	0.016
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.016
BAG2	BCL2-associated athanogene 2	0.016
AURKB	aurora kinase B	0.016
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.016
BARD1	BRCA1 associated RING domain 1	0.016
MTA2	metastasis associated 1 family, member 2	0.016
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.016
TGFB3	transforming growth factor, beta 3	0.016	Mouse
HUWE1	HECT, UBA and WWE domain containing 1	0.016
SKP2	S-phase kinase-associated protein 2 (p45)	0.016
RET	ret proto-oncogene	0.016
THBS1	thrombospondin 1	0.015
SOCS5	suppressor of cytokine signaling 5	0.015
ICAM1	intercellular adhesion molecule 1	0.015
PSEN2	presenilin 2 (Alzheimer disease 4)	0.015
NGFR	nerve growth factor receptor	0.015	Rat
CXCL10	chemokine (C-X-C motif) ligand 10	0.015
KSR1	kinase suppressor of ras 1	0.015
PHGDH	phosphoglycerate dehydrogenase	0.015
VDAC1	voltage-dependent anion channel 1	0.015
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.015
FOXO1	forkhead box O1	0.015	Human
TGFBR3	transforming growth factor, beta receptor III	0.015
ATM	ataxia telangiectasia mutated	0.015	Mouse
GAB1	GRB2-associated binding protein 1	0.015
PRKCE	protein kinase C, epsilon	0.015
SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like	0.015
RPS14	ribosomal protein S14	0.015
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.015
RPS4X	ribosomal protein S4, X-linked	0.015
FUS	fused in sarcoma	0.015
PDCD2	programmed cell death 2	0.015
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.015
LDHA	lactate dehydrogenase A	0.015
CHERP	calcium homeostasis endoplasmic reticulum protein	0.015
NONO	non-POU domain containing, octamer-binding	0.015
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.015
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.015
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.014
CREBZF	CREB/ATF bZIP transcription factor	0.014
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.014
PML	promyelocytic leukemia	0.014
CXCL13	chemokine (C-X-C motif) ligand 13	0.014
PNRC1	proline-rich nuclear receptor coactivator 1	0.014
WASL	Wiskott-Aldrich syndrome-like	0.014
RPLP0	ribosomal protein, large, P0	0.014
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.014
ARRB1	arrestin, beta 1	0.014
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.014
SATB2	SATB homeobox 2	0.014
CXCL3	chemokine (C-X-C motif) ligand 3	0.014
EPHA3	EPH receptor A3	0.014
WARS	tryptophanyl-tRNA synthetase	0.014
ICA1	islet cell autoantigen 1, 69kDa	0.014
SYK	spleen tyrosine kinase	0.014
CCL3	chemokine (C-C motif) ligand 3	0.014	Human Mouse
SNCAIP	synuclein, alpha interacting protein	0.014
CDK2	cyclin-dependent kinase 2	0.014
MSH3	mutS homolog 3 (E. coli)	0.014
CCR7	chemokine (C-C motif) receptor 7	0.014
CHRD	chordin	0.014
BBS10	Bardet-Biedl syndrome 10	0.014
PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	0.014
CXCL2	chemokine (C-X-C motif) ligand 2	0.014
RAN	RAN, member RAS oncogene family	0.014
TGFB2	transforming growth factor, beta 2	0.014
SPTBN1	spectrin, beta, non-erythrocytic 1	0.014
STMN2	stathmin-like 2	0.014
NFIL3	nuclear factor, interleukin 3 regulated	0.014
GCH1	GTP cyclohydrolase 1	0.014
RPL28	ribosomal protein L28	0.014
BAI1	brain-specific angiogenesis inhibitor 1	0.014
CARD11	caspase recruitment domain family, member 11	0.014
KCTD1	potassium channel tetramerisation domain containing 1	0.014
GRID2IP	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein	0.014
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.014
CDK16	cyclin-dependent kinase 16	0.014
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.014
IPO5	importin 5	0.014
PKN1	protein kinase N1	0.014
CD320	CD320 molecule	0.014
PCDHA4	protocadherin alpha 4	0.013
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.013	Human
RPL3	ribosomal protein L3	0.013
IL32	interleukin 32	0.013
TCP1	t-complex 1	0.013
IL1R1	interleukin 1 receptor, type I	0.013
HMGA1	high mobility group AT-hook 1	0.013
PLD3	phospholipase D family, member 3	0.013
EXT1	exostosin 1	0.013
GTF2I	general transcription factor IIi	0.013
CCR1	chemokine (C-C motif) receptor 1	0.013
CASP8AP2	caspase 8 associated protein 2	0.013
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.013
RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1	0.013
ZNF146	zinc finger protein 146	0.013
MAP2K7	mitogen-activated protein kinase kinase 7	0.013	Rat
DIABLO	diablo, IAP-binding mitochondrial protein	0.013
RANBP2	RAN binding protein 2	0.013
IL7R	interleukin 7 receptor	0.013
RPL4	ribosomal protein L4	0.013
IFNG	interferon, gamma	0.013
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.013
MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	0.013
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.013
CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	0.013
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.013
SERTAD4	SERTA domain containing 4	0.013
STC1	stanniocalcin 1	0.013
MAP2K1	mitogen-activated protein kinase kinase 1	0.013
CMIP	c-Maf-inducing protein	0.013
ATMIN	ATM interactor	0.013
BACE1	beta-site APP-cleaving enzyme 1	0.013
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.013
BIN1	bridging integrator 1	0.013
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	0.012
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.012
UBE3A	ubiquitin protein ligase E3A	0.012
PTK2	PTK2 protein tyrosine kinase 2	0.012
IRS2	insulin receptor substrate 2	0.012
EIF3G	eukaryotic translation initiation factor 3, subunit G	0.012
PNRC2	proline-rich nuclear receptor coactivator 2	0.012
PDPK1	3-phosphoinositide dependent protein kinase-1	0.012
PDE4D	phosphodiesterase 4D, cAMP-specific	0.012
SALL2	sal-like 2 (Drosophila)	0.012
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.012
ATF5	activating transcription factor 5	0.012
CAPRIN1	cell cycle associated protein 1	0.012
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.012
WBP4	WW domain binding protein 4 (formin binding protein 21)	0.012
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.012
DDR2	discoidin domain receptor tyrosine kinase 2	0.012
CNOT8	CCR4-NOT transcription complex, subunit 8	0.012
NCOA6	nuclear receptor coactivator 6	0.012
SOCS1	suppressor of cytokine signaling 1	0.012
CCND1	cyclin D1	0.012
RHOC	ras homolog gene family, member C	0.012
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012	Mouse
PHB	prohibitin	0.012
CCL7	chemokine (C-C motif) ligand 7	0.012	Human
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.012
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.012
SNIP1	Smad nuclear interacting protein 1	0.012
PICK1	protein interacting with PRKCA 1	0.012
SH3BP4	SH3-domain binding protein 4	0.012
ESR2	estrogen receptor 2 (ER beta)	0.012	Rat
MAP3K10	mitogen-activated protein kinase kinase kinase 10	0.012
TRIB1	tribbles homolog 1 (Drosophila)	0.012
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.012
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.012
HMOX2	heme oxygenase (decycling) 2	0.012
FBXW7	F-box and WD repeat domain containing 7	0.012
PSAT1	phosphoserine aminotransferase 1	0.012
MAP1S	microtubule-associated protein 1S	0.012
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.012
RHOA	ras homolog gene family, member A	0.012	Mouse
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.012
APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.012
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.012
CDCA8	cell division cycle associated 8	0.012
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.012
H2AFX	H2A histone family, member X	0.012
IL12RB2	interleukin 12 receptor, beta 2	0.012
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.012
DEDD	death effector domain containing	0.012
SSX4	synovial sarcoma, X breakpoint 4	0.012
CDCP1	CUB domain containing protein 1	0.012
STIP1	stress-induced-phosphoprotein 1	0.012
GRIP1	glutamate receptor interacting protein 1	0.012
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.012
JAG2	jagged 2	0.011
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.011
MXI1	MAX interactor 1	0.011
LPHN1	latrophilin 1	0.011
NUB1	negative regulator of ubiquitin-like proteins 1	0.011
ACTB	actin, beta	0.011
FKBP5	FK506 binding protein 5	0.011
SNAI1	snail homolog 1 (Drosophila)	0.011
AMPH	amphiphysin	0.011
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.011
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.011
NHEJ1	nonhomologous end-joining factor 1	0.011
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.011
NMT2	N-myristoyltransferase 2	0.011
MAPK11	mitogen-activated protein kinase 11	0.011
CXCL11	chemokine (C-X-C motif) ligand 11	0.011
ARHGAP31	Rho GTPase activating protein 31	0.011
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.011
CABP1	calcium binding protein 1	0.011
MFN1	mitofusin 1	0.011
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.011
NAP1L1	nucleosome assembly protein 1-like 1	0.011
ATR	ataxia telangiectasia and Rad3 related	0.011
PKP4	plakophilin 4	0.011
VDAC3	voltage-dependent anion channel 3	0.011
TF	transferrin	0.011
EFNA5	ephrin-A5	0.011
EYA2	eyes absent homolog 2 (Drosophila)	0.011
MAX	MYC associated factor X	0.011	Rat
GRIN3B	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	0.011
APOE	apolipoprotein E	0.011
AMBRA1	autophagy/beclin-1 regulator 1	0.011	Mouse
ADORA1	adenosine A1 receptor	0.011
NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.011
DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	0.011
CSF1	colony stimulating factor 1 (macrophage)	0.011
ARHGAP22	Rho GTPase activating protein 22	0.011
CXCL5	chemokine (C-X-C motif) ligand 5	0.011
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.011
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.011	Mouse
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.011
MTA3	metastasis associated 1 family, member 3	0.011
KRT6C	keratin 6C	0.011
SIX3	SIX homeobox 3	0.011
BMI1	BMI1 polycomb ring finger oncogene	0.011
BCL2L2	BCL2-like 2	0.011	Human
GATAD2B	GATA zinc finger domain containing 2B	0.011
ASNS	asparagine synthetase (glutamine-hydrolyzing)	0.011
TTR	transthyretin	0.011
CSK	c-src tyrosine kinase	0.011
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	0.011	Mouse
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.011
SKA1	spindle and kinetochore associated complex subunit 1	0.011
C14orf43	chromosome 14 open reading frame 43	0.011
SESN2	sestrin 2	0.010
CTSL1	cathepsin L1	0.010
IL1A	interleukin 1, alpha	0.010
CHPF	chondroitin polymerizing factor	0.010
FGFR1	fibroblast growth factor receptor 1	0.010
RPL32	ribosomal protein L32	0.010
ZNF512B	zinc finger protein 512B	0.010
RPS13	ribosomal protein S13	0.010
ZBTB4	zinc finger and BTB domain containing 4	0.010
ATG9A	ATG9 autophagy related 9 homolog A (S. cerevisiae)	0.010
TNK2	tyrosine kinase, non-receptor, 2	0.010
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.010
RCN2	reticulocalbin 2, EF-hand calcium binding domain	0.010
NPAS1	neuronal PAS domain protein 1	0.010	Human
HLTF	helicase-like transcription factor	0.010
CH25H	cholesterol 25-hydroxylase	0.010
SIRPA	signal-regulatory protein alpha	0.010
MAP1A	microtubule-associated protein 1A	0.010
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.010
ING1	inhibitor of growth family, member 1	0.010
IL13	interleukin 13	0.010
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.010
TAF1C	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	0.010
DUSP23	dual specificity phosphatase 23	0.010
ARHGAP32	Rho GTPase activating protein 32	0.010
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.010
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.010
GAB2	GRB2-associated binding protein 2	0.010
ACHE	acetylcholinesterase	0.010
EMX1	empty spiracles homeobox 1	0.010
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.010
IL10	interleukin 10	0.010