IMP: Integrative Multi-species Prediction

Homo sapiens

48 genes annotated in human

pattern recognition receptor signaling pathway

Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pattern recognition receptor signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "pattern recognition receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.999
IRAK1	interleukin-1 receptor-associated kinase 1	0.999
MYD88	myeloid differentiation primary response gene (88)	0.999	Mouse
BIRC3	baculoviral IAP repeat containing 3	0.999
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.998	Human
TRAF6	TNF receptor-associated factor 6	0.996
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.992
IRAK2	interleukin-1 receptor-associated kinase 2	0.992	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.987
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.950	Mouse
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.911
FKBP4	FK506 binding protein 4, 59kDa	0.863
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.800
S100A16	S100 calcium binding protein A16	0.790	Human
IFIH1	interferon induced with helicase C domain 1	0.779	Human
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.771
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.768
TNIP2	TNFAIP3 interacting protein 2	0.727	Mouse
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.723	Human
S100A14	S100 calcium binding protein A14	0.706
S100A1	S100 calcium binding protein A1	0.674	Human
TRAF1	TNF receptor-associated factor 1	0.664
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.656
TLR2	toll-like receptor 2	0.646
SAMD9	sterile alpha motif domain containing 9	0.642
MAPK14	mitogen-activated protein kinase 14	0.633
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.620
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.568	Human
RXRA	retinoid X receptor, alpha	0.566
TLR4	toll-like receptor 4	0.559
IFI44	interferon-induced protein 44	0.535
BIRC2	baculoviral IAP repeat containing 2	0.517
S100B	S100 calcium binding protein B	0.503	Human
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.483
SP100	SP100 nuclear antigen	0.452
S100A6	S100 calcium binding protein A6	0.451
IRF7	interferon regulatory factor 7	0.440	Mouse
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.426	Human
PELI3	pellino homolog 3 (Drosophila)	0.407	Mouse
ARRB1	arrestin, beta 1	0.384
TRIM22	tripartite motif containing 22	0.339	Human
IFIT3	interferon-induced protein with tetratricopeptide repeats 3	0.339
RIPK2	receptor-interacting serine-threonine kinase 2	0.323
TLR1	toll-like receptor 1	0.322	Human
IRAK3	interleukin-1 receptor-associated kinase 3	0.322	Human Mouse
SAMD9L	sterile alpha motif domain containing 9-like	0.297
MAPK1	mitogen-activated protein kinase 1	0.290
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.284
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.282
MED15	mediator complex subunit 15	0.275
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.269
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.262
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.239
TMEM173	transmembrane protein 173	0.239
S100A9	S100 calcium binding protein A9	0.237
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.229
SP110	SP110 nuclear body protein	0.228
IRAK4	interleukin-1 receptor-associated kinase 4	0.218
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.213	Human
CCR1	chemokine (C-C motif) receptor 1	0.206
TRIM21	tripartite motif containing 21	0.206	Human
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.201
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.187
TRAF3	TNF receptor-associated factor 3	0.183	Mouse
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.180
CD80	CD80 molecule	0.176
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.176
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.170
NMI	N-myc (and STAT) interactor	0.157
TNIP1	TNFAIP3 interacting protein 1	0.153	Mouse
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.152	Human
TRIM38	tripartite motif containing 38	0.148	Human
PILRA	paired immunoglobin-like type 2 receptor alpha	0.145
SIGLEC7	sialic acid binding Ig-like lectin 7	0.142
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.141
BTN3A3	butyrophilin, subfamily 3, member A3	0.140
CCR2	chemokine (C-C motif) receptor 2	0.136
NCOR2	nuclear receptor corepressor 2	0.135
PARP12	poly (ADP-ribose) polymerase family, member 12	0.131	Human
AGER	advanced glycosylation end product-specific receptor	0.130
TP53	tumor protein p53	0.130
CREBBP	CREB binding protein	0.123
TYMP	thymidine phosphorylase	0.122
GBP1	guanylate binding protein 1, interferon-inducible	0.122
CTSS	cathepsin S	0.121
S100A8	S100 calcium binding protein A8	0.120
NOD2	nucleotide-binding oligomerization domain containing 2	0.118
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.115
GBP3	guanylate binding protein 3	0.114
PTAFR	platelet-activating factor receptor	0.113	Mouse
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.106
TRIM5	tripartite motif containing 5	0.101
CRP	C-reactive protein, pentraxin-related	0.098
CYBB	cytochrome b-245, beta polypeptide	0.089
HSPB1	heat shock 27kDa protein 1	0.089
CAMP	cathelicidin antimicrobial peptide	0.084
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.084
ZNF263	zinc finger protein 263	0.083
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.082
IRF1	interferon regulatory factor 1	0.082	Mouse
IRF9	interferon regulatory factor 9	0.082
SMS	spermine synthase	0.081
IRF8	interferon regulatory factor 8	0.081
NLRC5	NLR family, CARD domain containing 5	0.080	Human
TNF	tumor necrosis factor	0.079
BTN3A1	butyrophilin, subfamily 3, member A1	0.078
VNN2	vanin 2	0.077
PIAS4	protein inhibitor of activated STAT, 4	0.074
TRIM17	tripartite motif containing 17	0.074	Human
HERC5	hect domain and RLD 5	0.074
IL15	interleukin 15	0.074
BCL3	B-cell CLL/lymphoma 3	0.072
CD14	CD14 molecule	0.072
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.072
S100A4	S100 calcium binding protein A4	0.071
TLR3	toll-like receptor 3	0.070
EPSTI1	epithelial stromal interaction 1 (breast)	0.070
TDRD7	tudor domain containing 7	0.069
CLEC7A	C-type lectin domain family 7, member A	0.068
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.066
HSF1	heat shock transcription factor 1	0.065
UBD	ubiquitin D	0.063
DTX3L	deltex 3-like (Drosophila)	0.061
BTN3A2	butyrophilin, subfamily 3, member A2	0.059
SIRPB1	signal-regulatory protein beta 1	0.059
CXCL11	chemokine (C-X-C motif) ligand 11	0.059
IL18RAP	interleukin 18 receptor accessory protein	0.058
OASL	2'-5'-oligoadenylate synthetase-like	0.057
IRF5	interferon regulatory factor 5	0.056
TREM1	triggering receptor expressed on myeloid cells 1	0.053
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.053
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.051
KLRC1	killer cell lectin-like receptor subfamily C, member 1	0.051	Human
MED25	mediator complex subunit 25	0.050
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.049
TRIM39	tripartite motif containing 39	0.048	Human
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.048
NCOA1	nuclear receptor coactivator 1	0.047
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.047
S100A12	S100 calcium binding protein A12	0.047	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.047
TFEC	transcription factor EC	0.047
HK3	hexokinase 3 (white cell)	0.046
AQP9	aquaporin 9	0.046
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.046	Human
HCST	hematopoietic cell signal transducer	0.045
TRAF2	TNF receptor-associated factor 2	0.045
ZC3H12A	zinc finger CCCH-type containing 12A	0.045
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.044
LY86	lymphocyte antigen 86	0.043
FPR1	formyl peptide receptor 1	0.043
LCN2	lipocalin 2	0.043
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.043
FCAR	Fc fragment of IgA, receptor for	0.043
CYTIP	cytohesin 1 interacting protein	0.042
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.042
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.042
DUSP1	dual specificity phosphatase 1	0.042
PARP9	poly (ADP-ribose) polymerase family, member 9	0.042
TRIM25	tripartite motif containing 25	0.041
FPR2	formyl peptide receptor 2	0.041
ZNF473	zinc finger protein 473	0.041
CD163	CD163 molecule	0.041
DUSP7	dual specificity phosphatase 7	0.040
IGF1R	insulin-like growth factor 1 receptor	0.040
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.040
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.040
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.040
IGSF6	immunoglobulin superfamily, member 6	0.039
FAS	Fas (TNF receptor superfamily, member 6)	0.039
PTPRR	protein tyrosine phosphatase, receptor type, R	0.039
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.039
CLEC18C	C-type lectin domain family 18, member C	0.039
HCP5	HLA complex P5	0.039
USP2	ubiquitin specific peptidase 2	0.039
RTP4	receptor (chemosensory) transporter protein 4	0.039
CLEC4A	C-type lectin domain family 4, member A	0.038
TRIM26	tripartite motif containing 26	0.038
ESR1	estrogen receptor 1	0.036
MPO	myeloperoxidase	0.036
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.036
RIPK3	receptor-interacting serine-threonine kinase 3	0.036	Human
XAF1	XIAP associated factor 1	0.036
DDX60L	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like	0.036	Human
TRAF3IP2	TRAF3 interacting protein 2	0.036
CD40	CD40 molecule, TNF receptor superfamily member 5	0.035
PEA15	phosphoprotein enriched in astrocytes 15	0.035
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.035
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.035
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.035
C5AR1	complement component 5a receptor 1	0.035
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.035
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.035
TLR8	toll-like receptor 8	0.034	Human
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.034
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.033
IL1RAP	interleukin 1 receptor accessory protein	0.032
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.032
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.032
LTF	lactotransferrin	0.032
LRP1	low density lipoprotein receptor-related protein 1	0.032
TRAF5	TNF receptor-associated factor 5	0.032
AREG	amphiregulin	0.032
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.032
STAT2	signal transducer and activator of transcription 2, 113kDa	0.031
S100P	S100 calcium binding protein P	0.031	Human
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.031
GPR97	G protein-coupled receptor 97	0.031
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.031
STAP2	signal transducing adaptor family member 2	0.030
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.030
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.030
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.030
CYLD	cylindromatosis (turban tumor syndrome)	0.030
APOL3	apolipoprotein L, 3	0.030
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.030
SBF1	SET binding factor 1	0.029
MAPK3	mitogen-activated protein kinase 3	0.029
IL1B	interleukin 1, beta	0.029
LIMK1	LIM domain kinase 1	0.029
HSPA1L	heat shock 70kDa protein 1-like	0.029
IFI16	interferon, gamma-inducible protein 16	0.029
IRF2	interferon regulatory factor 2	0.028
MED1	mediator complex subunit 1	0.028
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.028
PRKCZ	protein kinase C, zeta	0.028
NLRP3	NLR family, pyrin domain containing 3	0.028	Human
CLEC5A	C-type lectin domain family 5, member A	0.028
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.028
TICAM1	toll-like receptor adaptor molecule 1	0.027	Mouse
GBP5	guanylate binding protein 5	0.027
APOL6	apolipoprotein L, 6	0.027
CD180	CD180 molecule	0.027	Human
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.027
MCOLN1	mucolipin 1	0.026
NELL2	NEL-like 2 (chicken)	0.026
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.026
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.026
CCL5	chemokine (C-C motif) ligand 5	0.026
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.026
C5orf56	chromosome 5 open reading frame 56	0.026
IL10	interleukin 10	0.026
KLHL24	kelch-like 24 (Drosophila)	0.026
IFI44L	interferon-induced protein 44-like	0.025
PHC2	polyhomeotic homolog 2 (Drosophila)	0.025
NLRC4	NLR family, CARD domain containing 4	0.025
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.025
RSAD2	radical S-adenosyl methionine domain containing 2	0.025	Mouse
IL1RN	interleukin 1 receptor antagonist	0.025
GPR65	G protein-coupled receptor 65	0.025
SECTM1	secreted and transmembrane 1	0.025
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.025
SASH3	SAM and SH3 domain containing 3	0.025
DUSP3	dual specificity phosphatase 3	0.025
RNF213	ring finger protein 213	0.025
SELL	selectin L	0.025
SIGLEC5	sialic acid binding Ig-like lectin 5	0.025
CARD11	caspase recruitment domain family, member 11	0.025
CTSG	cathepsin G	0.025
RARA	retinoic acid receptor, alpha	0.024	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.024
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.024
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.024
DEFA4	defensin, alpha 4, corticostatin	0.024
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.024
RNASE3	ribonuclease, RNase A family, 3	0.024
CD69	CD69 molecule	0.024
TRAF3IP3	TRAF3 interacting protein 3	0.024
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.024
SLFN12	schlafen family member 12	0.024
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.024
CLEC4E	C-type lectin domain family 4, member E	0.024
ZBP1	Z-DNA binding protein 1	0.024
GIMAP2	GTPase, IMAP family member 2	0.024
CD83	CD83 molecule	0.023
PI3	peptidase inhibitor 3, skin-derived	0.023
SPHK1	sphingosine kinase 1	0.023
PIM1	pim-1 oncogene	0.023
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.023
TLR6	toll-like receptor 6	0.023	Human
MARCH1	membrane-associated ring finger (C3HC4) 1	0.023
TARBP2	TAR (HIV-1) RNA binding protein 2	0.023
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.023
CCR5	chemokine (C-C motif) receptor 5	0.023
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.023
ANG	angiogenin, ribonuclease, RNase A family, 5	0.023
SIGLEC9	sialic acid binding Ig-like lectin 9	0.023
GPR171	G protein-coupled receptor 171	0.023
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.023
IFNG	interferon, gamma	0.023
IL15RA	interleukin 15 receptor, alpha	0.022
ARHGAP9	Rho GTPase activating protein 9	0.022
HP	haptoglobin	0.022
BST1	bone marrow stromal cell antigen 1	0.022
AIM2	absent in melanoma 2	0.022
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.022
C4BPA	complement component 4 binding protein, alpha	0.022
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.022
MPEG1	macrophage expressed 1	0.022
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.022
IL10RA	interleukin 10 receptor, alpha	0.022
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.022
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.022
STAT1	signal transducer and activator of transcription 1, 91kDa	0.021
ISG20	interferon stimulated exonuclease gene 20kDa	0.021
PRKD2	protein kinase D2	0.021
TLR5	toll-like receptor 5	0.021
CCDC50	coiled-coil domain containing 50	0.021
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.021
MSTO1	misato homolog 1 (Drosophila)	0.021
CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.021
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.021
CD48	CD48 molecule	0.021
LY96	lymphocyte antigen 96	0.021
TADA3	transcriptional adaptor 3	0.021
MR1	major histocompatibility complex, class I-related	0.021
USHBP1	Usher syndrome 1C binding protein 1	0.021
BTK	Bruton agammaglobulinemia tyrosine kinase	0.021
GBP2	guanylate binding protein 2, interferon-inducible	0.020
PDZK1IP1	PDZK1 interacting protein 1	0.020
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.020
HECTD1	HECT domain containing 1	0.020
TLR9	toll-like receptor 9	0.020
ARRB2	arrestin, beta 2	0.020	Mouse
CD28	CD28 molecule	0.020
SORBS3	sorbin and SH3 domain containing 3	0.020
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.020
AOAH	acyloxyacyl hydrolase (neutrophil)	0.020
RNF126	ring finger protein 126	0.020
MICA	MHC class I polypeptide-related sequence A	0.020
STX11	syntaxin 11	0.020
ELANE	elastase, neutrophil expressed	0.019
CTSO	cathepsin O	0.019
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	0.019
RGS18	regulator of G-protein signaling 18	0.019
MAP2K1	mitogen-activated protein kinase kinase 1	0.019
CCL20	chemokine (C-C motif) ligand 20	0.019
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.019
CCL4	chemokine (C-C motif) ligand 4	0.019
CUL1	cullin 1	0.019
SLAMF7	SLAM family member 7	0.019
GZMK	granzyme K (granzyme 3; tryptase II)	0.019
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.019
SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	0.019
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.019
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.019
YBX1	Y box binding protein 1	0.019
APOBEC3A	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	0.019
C19orf66	chromosome 19 open reading frame 66	0.019
ALOX5	arachidonate 5-lipoxygenase	0.019
KIAA1274	KIAA1274	0.019
MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	0.018
DOCK8	dedicator of cytokinesis 8	0.018
KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	0.018
MAP2K3	mitogen-activated protein kinase kinase 3	0.018
MAGEB18	melanoma antigen family B, 18	0.018
HLA-F	major histocompatibility complex, class I, F	0.018
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.018
TRIM34	tripartite motif containing 34	0.018
MLKL	mixed lineage kinase domain-like	0.018
FTH1	ferritin, heavy polypeptide 1	0.018
CD1C	CD1c molecule	0.018
CD160	CD160 molecule	0.018
RHAG	Rh-associated glycoprotein	0.018
PHF11	PHD finger protein 11	0.018
CDA	cytidine deaminase	0.018
DHRS9	dehydrogenase/reductase (SDR family) member 9	0.018
CFP	complement factor properdin	0.018
FFAR2	free fatty acid receptor 2	0.018
RYBP	RING1 and YY1 binding protein	0.018
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.018
FGL2	fibrinogen-like 2	0.018
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.018
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.018
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.017
MTPN	myotrophin	0.017
VNN1	vanin 1	0.017
RETN	resistin	0.017
TRAFD1	TRAF-type zinc finger domain containing 1	0.017
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.017
ICOS	inducible T-cell co-stimulator	0.017
S100A2	S100 calcium binding protein A2	0.017	Human
RXRG	retinoid X receptor, gamma	0.017
FOLR3	folate receptor 3 (gamma)	0.017
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.017
IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	0.017
NCOA3	nuclear receptor coactivator 3	0.017
ITGB5	integrin, beta 5	0.017
SLPI	secretory leukocyte peptidase inhibitor	0.017
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.017
MAPK11	mitogen-activated protein kinase 11	0.017
SPOP	speckle-type POZ protein	0.017
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.017
KRT23	keratin 23 (histone deacetylase inducible)	0.017
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.017
C1orf93	chromosome 1 open reading frame 93	0.017
PARP14	poly (ADP-ribose) polymerase family, member 14	0.016
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.016
CSDA	cold shock domain protein A	0.016
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.016
KLRF1	killer cell lectin-like receptor subfamily F, member 1	0.016
SREBF1	sterol regulatory element binding transcription factor 1	0.016
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.016
GPR183	G protein-coupled receptor 183	0.016
BTN2A2	butyrophilin, subfamily 2, member A2	0.016
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.016
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.016
ELF4	E74-like factor 4 (ets domain transcription factor)	0.016
SPATA24	spermatogenesis associated 24	0.016
GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.016
LAMB3	laminin, beta 3	0.016
MBP	myelin basic protein	0.016
TREML1	triggering receptor expressed on myeloid cells-like 1	0.016
PELI1	pellino homolog 1 (Drosophila)	0.016	Mouse
DEFA1B	defensin, alpha 1B	0.016
ORM1	orosomucoid 1	0.016
PPARA	peroxisome proliferator-activated receptor alpha	0.016
CD1D	CD1d molecule	0.016
S100A11	S100 calcium binding protein A11	0.016
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.016
UNC93B1	unc-93 homolog B1 (C. elegans)	0.016
PLEK	pleckstrin	0.015
MPRIP	myosin phosphatase Rho interacting protein	0.015
CRTAM	cytotoxic and regulatory T cell molecule	0.015
GPR18	G protein-coupled receptor 18	0.015	Human
ARG1	arginase, liver	0.015
ADAMDEC1	ADAM-like, decysin 1	0.015
KANK2	KN motif and ankyrin repeat domains 2	0.015
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.015
GPR109B	G protein-coupled receptor 109B	0.015
MAP2K4	mitogen-activated protein kinase kinase 4	0.015
TAGAP	T-cell activation RhoGTPase activating protein	0.015
HERC6	hect domain and RLD 6	0.015
KIF1C	kinesin family member 1C	0.015
LAMC2	laminin, gamma 2	0.015
EMR2	egf-like module containing, mucin-like, hormone receptor-like 2	0.015
PRF1	perforin 1 (pore forming protein)	0.015
ASGR2	asialoglycoprotein receptor 2	0.015
TXN	thioredoxin	0.015
ARIH2	ariadne homolog 2 (Drosophila)	0.015
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.015
MKRN3	makorin ring finger protein 3	0.015
CXCR6	chemokine (C-X-C motif) receptor 6	0.015
SARM1	sterile alpha and TIR motif containing 1	0.015
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.015
APOBR	apolipoprotein B receptor	0.015
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.014
CCL8	chemokine (C-C motif) ligand 8	0.014
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.014
LAMP3	lysosomal-associated membrane protein 3	0.014
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.014
STK4	serine/threonine kinase 4	0.014
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.014
SLC15A3	solute carrier family 15, member 3	0.014
TICAM2	toll-like receptor adaptor molecule 2	0.014
KLRC3	killer cell lectin-like receptor subfamily C, member 3	0.014	Human
C1orf38	chromosome 1 open reading frame 38	0.014
RXRB	retinoid X receptor, beta	0.014
RNF19B	ring finger protein 19B	0.014
PTPRA	protein tyrosine phosphatase, receptor type, A	0.014
ADAP2	ArfGAP with dual PH domains 2	0.014
CD177	CD177 molecule	0.014
ACY3	aspartoacylase (aminocyclase) 3	0.014
TRIM14	tripartite motif containing 14	0.014
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.014
TOLLIP	toll interacting protein	0.014
TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	0.014
CLC	Charcot-Leyden crystal protein	0.014
PDIA3	protein disulfide isomerase family A, member 3	0.014
TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough	0.014
SLAMF6	SLAM family member 6	0.014
GYPE	glycophorin E (MNS blood group)	0.014
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.014
GPR84	G protein-coupled receptor 84	0.014
LY75	lymphocyte antigen 75	0.014
TLR7	toll-like receptor 7	0.014	Human Mouse Rat
IDO1	indoleamine 2,3-dioxygenase 1	0.014
CLEC4D	C-type lectin domain family 4, member D	0.014
GBP4	guanylate binding protein 4	0.014
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.014
RHBDF2	rhomboid 5 homolog 2 (Drosophila)	0.013
C17orf62	chromosome 17 open reading frame 62	0.013
SGK1	serum/glucocorticoid regulated kinase 1	0.013
MSR1	macrophage scavenger receptor 1	0.013
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.013
BIN2	bridging integrator 2	0.013
TRIM35	tripartite motif containing 35	0.013
ACSL5	acyl-CoA synthetase long-chain family member 5	0.013
IL8	interleukin 8	0.013
TDGF1	teratocarcinoma-derived growth factor 1	0.013
ICAM1	intercellular adhesion molecule 1	0.013
OLFML3	olfactomedin-like 3	0.013
GAB2	GRB2-associated binding protein 2	0.013
DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.013
PROCR	protein C receptor, endothelial	0.013
CLEC2D	C-type lectin domain family 2, member D	0.013
DPEP2	dipeptidase 2	0.013
CP	ceruloplasmin (ferroxidase)	0.013
UBTD1	ubiquitin domain containing 1	0.013
CD33	CD33 molecule	0.013
AMICA1	adhesion molecule, interacts with CXADR antigen 1	0.013
MYO1D	myosin ID	0.013
S100A7	S100 calcium binding protein A7	0.013
LRRC25	leucine rich repeat containing 25	0.013
PLB1	phospholipase B1	0.013
HECTD3	HECT domain containing 3	0.013
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.013	Human
PF4	platelet factor 4	0.013
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.013
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.013
UBA7	ubiquitin-like modifier activating enzyme 7	0.013
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.013
FAM129A	family with sequence similarity 129, member A	0.013
OSM	oncostatin M	0.013
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.013
EVI2B	ecotropic viral integration site 2B	0.013
PRKCA	protein kinase C, alpha	0.013
CD300C	CD300c molecule	0.013
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.012
PTMA	prothymosin, alpha	0.012
EIF4A1	eukaryotic translation initiation factor 4A1	0.012
BCL10	B-cell CLL/lymphoma 10	0.012
VENTX	VENT homeobox homolog (Xenopus laevis)	0.012
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.012
ALPL	alkaline phosphatase, liver/bone/kidney	0.012
CD226	CD226 molecule	0.012
PPA1	pyrophosphatase (inorganic) 1	0.012
FLT3	fms-related tyrosine kinase 3	0.012
PARP8	poly (ADP-ribose) polymerase family, member 8	0.012
IL24	interleukin 24	0.012
HIST2H2AB	histone cluster 2, H2ab	0.012
CMTM2	CKLF-like MARVEL transmembrane domain containing 2	0.012
CXCR2	chemokine (C-X-C motif) receptor 2	0.012
USP15	ubiquitin specific peptidase 15	0.012
HOXB7	homeobox B7	0.012
CRABP2	cellular retinoic acid binding protein 2	0.012
TOM1	target of myb1 (chicken)	0.012
TRIM32	tripartite motif containing 32	0.012
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.012
CD84	CD84 molecule	0.012
SIGLEC12	sialic acid binding Ig-like lectin 12	0.012
GORAB	golgin, RAB6-interacting	0.012
TRIM52	tripartite motif containing 52	0.012
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.012
MARCO	macrophage receptor with collagenous structure	0.012
SPRR2A	small proline-rich protein 2A	0.012
RIPK4	receptor-interacting serine-threonine kinase 4	0.012	Human
ALAS2	aminolevulinate, delta-, synthase 2	0.012
ZNRF3	zinc and ring finger 3	0.012
IPCEF1	interaction protein for cytohesin exchange factors 1	0.012
SIGLEC10	sialic acid binding Ig-like lectin 10	0.012
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.012
LY6D	lymphocyte antigen 6 complex, locus D	0.012
HPSE	heparanase	0.012
JMY	junction mediating and regulatory protein, p53 cofactor	0.012
NOD1	nucleotide-binding oligomerization domain containing 1	0.012
SLC25A28	solute carrier family 25, member 28	0.012
CARD6	caspase recruitment domain family, member 6	0.012
PLCD4	phospholipase C, delta 4	0.012
XDH	xanthine dehydrogenase	0.012
EDF1	endothelial differentiation-related factor 1	0.012
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.012
RGL4	ral guanine nucleotide dissociation stimulator-like 4	0.012
PADI2	peptidyl arginine deiminase, type II	0.012
JAG2	jagged 2	0.012
RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	0.012
HAVCR2	hepatitis A virus cellular receptor 2	0.012
CD300A	CD300a molecule	0.012
USP26	ubiquitin specific peptidase 26	0.012
STX5	syntaxin 5	0.012
XIAP	X-linked inhibitor of apoptosis	0.012
KLRC4	killer cell lectin-like receptor subfamily C, member 4	0.012	Human
CD86	CD86 molecule	0.012	Mouse
BPI	bactericidal/permeability-increasing protein	0.012	Human
DENND3	DENN/MADD domain containing 3	0.012
DUSP16	dual specificity phosphatase 16	0.012
CCR6	chemokine (C-C motif) receptor 6	0.012
C17orf60	chromosome 17 open reading frame 60	0.012
CD300LF	CD300 molecule-like family member f	0.012
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.012
RNF5	ring finger protein 5	0.012
PRSS22	protease, serine, 22	0.011
PDZD4	PDZ domain containing 4	0.011
CD101	CD101 molecule	0.011
ADORA3	adenosine A3 receptor	0.011
DENND2D	DENN/MADD domain containing 2D	0.011
KLF5	Kruppel-like factor 5 (intestinal)	0.011
STRN	striatin, calmodulin binding protein	0.011
ETV7	ets variant 7	0.011
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.011
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.011
PDE4D	phosphodiesterase 4D, cAMP-specific	0.011
MNDA	myeloid cell nuclear differentiation antigen	0.011
KRT1	keratin 1	0.011
GIMAP4	GTPase, IMAP family member 4	0.011
CDCP1	CUB domain containing protein 1	0.011
CXCR1	chemokine (C-X-C motif) receptor 1	0.011
PGLYRP1	peptidoglycan recognition protein 1	0.011
PDK4	pyruvate dehydrogenase kinase, isozyme 4	0.011
CIDEA	cell death-inducing DFFA-like effector a	0.011
JAK2	Janus kinase 2	0.011
IL1R2	interleukin 1 receptor, type II	0.011
SORBS2	sorbin and SH3 domain containing 2	0.011
ANXA1	annexin A1	0.011
APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.011
S100A3	S100 calcium binding protein A3	0.011	Human
TREML2	triggering receptor expressed on myeloid cells-like 2	0.011
KRT17	keratin 17	0.011
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.011
TNFRSF17	tumor necrosis factor receptor superfamily, member 17	0.011
STAT4	signal transducer and activator of transcription 4	0.011
C19orf59	chromosome 19 open reading frame 59	0.011
PRKCD	protein kinase C, delta	0.011
ADRB2	adrenergic, beta-2-, receptor, surface	0.011
PTGES	prostaglandin E synthase	0.011
AZU1	azurocidin 1	0.011
RAB5C	RAB5C, member RAS oncogene family	0.011
CARD16	caspase recruitment domain family, member 16	0.011
PRKCDBP	protein kinase C, delta binding protein	0.011
KLHL6	kelch-like 6 (Drosophila)	0.011
F5	coagulation factor V (proaccelerin, labile factor)	0.011
PLBD1	phospholipase B domain containing 1	0.011
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.011
SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	0.011
CXCR4	chemokine (C-X-C motif) receptor 4	0.011
BEST1	bestrophin 1	0.011
HLA-C	major histocompatibility complex, class I, C	0.011
CMIP	c-Maf-inducing protein	0.011
CRYAB	crystallin, alpha B	0.011
STEAP4	STEAP family member 4	0.011
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.011
TLR10	toll-like receptor 10	0.011	Human
RUNDC3A	RUN domain containing 3A	0.011
ERAP2	endoplasmic reticulum aminopeptidase 2	0.011
IL32	interleukin 32	0.011
NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	0.011
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.011
GPR77	G protein-coupled receptor 77	0.011
PADI4	peptidyl arginine deiminase, type IV	0.011
SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	0.011
HLA-B	major histocompatibility complex, class I, B	0.011
CMKLR1	chemokine-like receptor 1	0.011
ANKS3	ankyrin repeat and sterile alpha motif domain containing 3	0.011
LRG1	leucine-rich alpha-2-glycoprotein 1	0.011
FABP4	fatty acid binding protein 4, adipocyte	0.011
GPBAR1	G protein-coupled bile acid receptor 1	0.011
ADAM8	ADAM metallopeptidase domain 8	0.011
AIM1	absent in melanoma 1	0.011
NINJ1	ninjurin 1	0.010
VIL1	villin 1	0.010
LSR	lipolysis stimulated lipoprotein receptor	0.010
MAP2K6	mitogen-activated protein kinase kinase 6	0.010
CCR3	chemokine (C-C motif) receptor 3	0.010
C15orf39	chromosome 15 open reading frame 39	0.010
CYSLTR1	cysteinyl leukotriene receptor 1	0.010
RHCG	Rh family, C glycoprotein	0.010
KLRG1	killer cell lectin-like receptor subfamily G, member 1	0.010	Human
SLC16A5	solute carrier family 16, member 5 (monocarboxylic acid transporter 6)	0.010
CXCL16	chemokine (C-X-C motif) ligand 16	0.010
DUSP9	dual specificity phosphatase 9	0.010
MGAM	maltase-glucoamylase (alpha-glucosidase)	0.010
RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	0.010
CD40LG	CD40 ligand	0.010
GOLGA2	golgin A2	0.010
EHD1	EH-domain containing 1	0.010
MBOAT7	membrane bound O-acyltransferase domain containing 7	0.010
ITPKC	inositol-trisphosphate 3-kinase C	0.010
CCL1	chemokine (C-C motif) ligand 1	0.010
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.010
CCR8	chemokine (C-C motif) receptor 8	0.010
HAL	histidine ammonia-lyase	0.010
TXK	TXK tyrosine kinase	0.010
PELI2	pellino homolog 2 (Drosophila)	0.010
LRMP	lymphoid-restricted membrane protein	0.010
DLG3	discs, large homolog 3 (Drosophila)	0.010
MPZL2	myelin protein zero-like 2	0.010
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.010
CCR7	chemokine (C-C motif) receptor 7	0.010
SP140L	SP140 nuclear body protein-like	0.010
MAGEF1	melanoma antigen family F, 1	0.010
GP9	glycoprotein IX (platelet)	0.010
IL2RB	interleukin 2 receptor, beta	0.010
PSTPIP2	proline-serine-threonine phosphatase interacting protein 2	0.010
TFEB	transcription factor EB	0.010
FKBP3	FK506 binding protein 3, 25kDa	0.010
SIRPA	signal-regulatory protein alpha	0.010
NCR1	natural cytotoxicity triggering receptor 1	0.010
LDHB	lactate dehydrogenase B	0.010
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.010
AIP	aryl hydrocarbon receptor interacting protein	0.010
MBL2	mannose-binding lectin (protein C) 2, soluble	0.010
CSTA	cystatin A (stefin A)	0.010
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.010
DOK3	docking protein 3	0.010
S100Z	S100 calcium binding protein Z	0.010	Human
OLFM4	olfactomedin 4	0.010
EFS	embryonal Fyn-associated substrate	0.010
SIRPB2	signal-regulatory protein beta 2	0.010