IMP: Integrative Multi-species Prediction

Homo sapiens

48 genes annotated in human

Multi-species View

positive regulation of protein localization to nucleus

GO:1900182

Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of protein localization to nucleus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of protein localization to nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD3	SMAD family member 3	0.989
SMAD7	SMAD family member 7	0.968	Human
SMAD4	SMAD family member 4	0.957	Human Mouse
SMAD2	SMAD family member 2	0.942	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.885	Human
EGFR	epidermal growth factor receptor	0.883
SH3KBP1	SH3-domain kinase binding protein 1	0.869
BMPR1A	bone morphogenetic protein receptor, type IA	0.841
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.806	Human
IQGAP1	IQ motif containing GTPase activating protein 1	0.719
GRB2	growth factor receptor-bound protein 2	0.711
IL8	interleukin 8	0.676
ESR1	estrogen receptor 1	0.630
FLNA	filamin A, alpha	0.584
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.555
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.487	Human
CCL4	chemokine (C-C motif) ligand 4	0.486	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.465
FAF1	Fas (TNFRSF6) associated factor 1	0.459
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.434	Human
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.422
CXCL3	chemokine (C-X-C motif) ligand 3	0.421
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.401
SH2D4A	SH2 domain containing 4A	0.394
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.386
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.381
CCR5	chemokine (C-C motif) receptor 5	0.374
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.361
NCOA1	nuclear receptor coactivator 1	0.347
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.342
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.331
IL1R1	interleukin 1 receptor, type I	0.329
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.306
FKBP1A	FK506 binding protein 1A, 12kDa	0.298
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.273
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.269
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.257
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.253
BMP2	bone morphogenetic protein 2	0.246	Human
SRPK2	SRSF protein kinase 2	0.240	Yeast
SOCS3	suppressor of cytokine signaling 3	0.233
MYH9	myosin, heavy chain 9, non-muscle	0.231
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.218
BMPR1B	bone morphogenetic protein receptor, type IB	0.211	Human
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.207
TGFB1	transforming growth factor, beta 1	0.206
CCL8	chemokine (C-C motif) ligand 8	0.203	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.200	Human
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.198
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.193
YAP1	Yes-associated protein 1	0.185
CXCL10	chemokine (C-X-C motif) ligand 10	0.183
IL6	interleukin 6 (interferon, beta 2)	0.179
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.178
RACGAP1	Rac GTPase activating protein 1	0.176
TGFBR1	transforming growth factor, beta receptor 1	0.175
FBXW11	F-box and WD repeat domain containing 11	0.173	Fly
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.172
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.165
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.162
PSEN1	presenilin 1	0.158
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.154
MYD88	myeloid differentiation primary response gene (88)	0.146
LMNA	lamin A/C	0.139
IGF1R	insulin-like growth factor 1 receptor	0.134
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.132
RNF31	ring finger protein 31	0.130
IDE	insulin-degrading enzyme	0.127
ZNF84	zinc finger protein 84	0.125
CDK8	cyclin-dependent kinase 8	0.124
BTRC	beta-transducin repeat containing	0.123	Fly
FSTL1	follistatin-like 1	0.119
KPNB1	karyopherin (importin) beta 1	0.118	Fly
CUL1	cullin 1	0.117
DSG2	desmoglein 2	0.115
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.112
RIPK2	receptor-interacting serine-threonine kinase 2	0.110
GDF5	growth differentiation factor 5	0.106	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.106
SYK	spleen tyrosine kinase	0.103
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.101
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.097
ANGPT1	angiopoietin 1	0.096
SNAI1	snail homolog 1 (Drosophila)	0.095
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.095
ANGPT2	angiopoietin 2	0.093
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.092
HIPK3	homeodomain interacting protein kinase 3	0.089
BAIAP2	BAI1-associated protein 2	0.089
UBXN1	UBX domain protein 1	0.089
CCR1	chemokine (C-C motif) receptor 1	0.088
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.087
TGFB3	transforming growth factor, beta 3	0.086	Mouse
VCP	valosin containing protein	0.084	Yeast
DPP4	dipeptidyl-peptidase 4	0.082
PLAUR	plasminogen activator, urokinase receptor	0.082
SFN	stratifin	0.079
FOXD3	forkhead box D3	0.079
ACTN4	actinin, alpha 4	0.078
FYN	FYN oncogene related to SRC, FGR, YES	0.077	Mouse
PBK	PDZ binding kinase	0.077
ACTN1	actinin, alpha 1	0.075
STAT1	signal transducer and activator of transcription 1, 91kDa	0.070
NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	0.070
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.068
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.067
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.067
WASL	Wiskott-Aldrich syndrome-like	0.066
FZD1	frizzled homolog 1 (Drosophila)	0.066
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.065
APP	amyloid beta (A4) precursor protein	0.064
CBX5	chromobox homolog 5	0.063
TNF	tumor necrosis factor	0.063
LRRK2	leucine-rich repeat kinase 2	0.063
MAVS	mitochondrial antiviral signaling protein	0.062
ICAM1	intercellular adhesion molecule 1	0.061
NOG	noggin	0.061
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.060
ZMYND11	zinc finger, MYND-type containing 11	0.060
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.058
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.058
SOX10	SRY (sex determining region Y)-box 10	0.054
CXCL5	chemokine (C-X-C motif) ligand 5	0.054
SKIL	SKI-like oncogene	0.053
SKA3	spindle and kinetochore associated complex subunit 3	0.053
SPRR2A	small proline-rich protein 2A	0.052
CCL2	chemokine (C-C motif) ligand 2	0.052	Human
HOXA9	homeobox A9	0.051
BTK	Bruton agammaglobulinemia tyrosine kinase	0.051
HMG20A	high mobility group 20A	0.051
BIRC3	baculoviral IAP repeat containing 3	0.050
SMAD1	SMAD family member 1	0.050	Human
BCL2A1	BCL2-related protein A1	0.049
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.049
LAT	linker for activation of T cells	0.049
IRF2	interferon regulatory factor 2	0.049
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.049
WIPF1	WAS/WASL interacting protein family, member 1	0.048
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.048
TRIM25	tripartite motif containing 25	0.048
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.048
JUP	junction plakoglobin	0.047
MBOAT7	membrane bound O-acyltransferase domain containing 7	0.047
TRIM21	tripartite motif containing 21	0.047
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.046
GRB7	growth factor receptor-bound protein 7	0.045
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.045
RXRA	retinoid X receptor, alpha	0.045
FLNB	filamin B, beta	0.045	Human
CCL13	chemokine (C-C motif) ligand 13	0.044	Human
CD83	CD83 molecule	0.044
PDLIM7	PDZ and LIM domain 7 (enigma)	0.044
INHBA	inhibin, beta A	0.043
NBN	nibrin	0.043
PAX3	paired box 3	0.043
CD2	CD2 molecule	0.043
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.043
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.042
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.042	Human
SOX2	SRY (sex determining region Y)-box 2	0.041
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.041
SH3BP2	SH3-domain binding protein 2	0.040
CRIPAK	cysteine-rich PAK1 inhibitor	0.039
CCL3	chemokine (C-C motif) ligand 3	0.039	Human
LY96	lymphocyte antigen 96	0.039
HCFC1	host cell factor C1 (VP16-accessory protein)	0.038
ITGB1BP3	integrin beta 1 binding protein 3	0.037
ITGB4	integrin, beta 4	0.037
TNPO1	transportin 1	0.037
SH3RF3	SH3 domain containing ring finger 3	0.036
TLR2	toll-like receptor 2	0.036
CYLD	cylindromatosis (turban tumor syndrome)	0.036
LBR	lamin B receptor	0.036
CCL7	chemokine (C-C motif) ligand 7	0.036	Human
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.035
BBS10	Bardet-Biedl syndrome 10	0.035
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.035
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.035
LRP6	low density lipoprotein receptor-related protein 6	0.035	Human
GSK3B	glycogen synthase kinase 3 beta	0.034
DSP	desmoplakin	0.034
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.034
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.034
VAV1	vav 1 guanine nucleotide exchange factor	0.034
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.033
TRIM37	tripartite motif containing 37	0.033
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.032	Yeast
ACVR1	activin A receptor, type I	0.032	Human
PKP2	plakophilin 2	0.032
ZNF140	zinc finger protein 140	0.032	Human
CCR4	chemokine (C-C motif) receptor 4	0.031
ARRB1	arrestin, beta 1	0.031
TCF12	transcription factor 12	0.031
RANBP9	RAN binding protein 9	0.031
USP9X	ubiquitin specific peptidase 9, X-linked	0.031
SKP1	S-phase kinase-associated protein 1	0.030
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.030
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.030
PLEC	plectin	0.030
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.030
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.029
USP15	ubiquitin specific peptidase 15	0.029
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.029
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.029
MEOX2	mesenchyme homeobox 2	0.029
DLG4	discs, large homolog 4 (Drosophila)	0.029
POGZ	pogo transposable element with ZNF domain	0.029
APC	adenomatous polyposis coli	0.028
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.028
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.028
KPNA6	karyopherin alpha 6 (importin alpha 7)	0.028
CPNE6	copine VI (neuronal)	0.028
TRAF1	TNF receptor-associated factor 1	0.028
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.028
SLAMF7	SLAM family member 7	0.028
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.028
TICAM2	toll-like receptor adaptor molecule 2	0.027
IL1B	interleukin 1, beta	0.027
ZFYVE9	zinc finger, FYVE domain containing 9	0.027
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.027	Yeast
ZNF260	zinc finger protein 260	0.027
BLNK	B-cell linker	0.027
NSFL1C	NSFL1 (p97) cofactor (p47)	0.027
CXCL9	chemokine (C-X-C motif) ligand 9	0.026
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.026	Human
ACVR2B	activin A receptor, type IIB	0.026
RAG1	recombination activating gene 1	0.026
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.026
NCF2	neutrophil cytosolic factor 2	0.026
SELE	selectin E	0.026
MAGEA11	melanoma antigen family A, 11	0.026
PRKG1	protein kinase, cGMP-dependent, type I	0.026
MDC1	mediator of DNA-damage checkpoint 1	0.026
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.026
CH25H	cholesterol 25-hydroxylase	0.025
ENG	endoglin	0.025
LIMK1	LIM domain kinase 1	0.025
CCL1	chemokine (C-C motif) ligand 1	0.025	Human
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.025
CXCL13	chemokine (C-X-C motif) ligand 13	0.025
NUP153	nucleoporin 153kDa	0.025
CCL11	chemokine (C-C motif) ligand 11	0.025	Human
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.025
TLR1	toll-like receptor 1	0.025	Human
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.025
CAPRIN2	caprin family member 2	0.025
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.025
SKA2	spindle and kinetochore associated complex subunit 2	0.025
ZNF12	zinc finger protein 12	0.024
VCAM1	vascular cell adhesion molecule 1	0.024
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.024
TRIM43	tripartite motif containing 43	0.024
MSC	musculin	0.024
CSF1	colony stimulating factor 1 (macrophage)	0.024
TMEM173	transmembrane protein 173	0.023
IFNG	interferon, gamma	0.023
PARP12	poly (ADP-ribose) polymerase family, member 12	0.023
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.023
DBN1	drebrin 1	0.023	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.023
IL7R	interleukin 7 receptor	0.023
SORBS2	sorbin and SH3 domain containing 2	0.023
ZNF585A	zinc finger protein 585A	0.023
TRADD	TNFRSF1A-associated via death domain	0.023
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.023
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.023
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.023
SMAD6	SMAD family member 6	0.023	Human
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.022
EBI3	Epstein-Barr virus induced 3	0.022
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.022
ZNF623	zinc finger protein 623	0.022
CNN2	calponin 2	0.022
HDAC6	histone deacetylase 6	0.022
CCL20	chemokine (C-C motif) ligand 20	0.022	Human
WEE1	WEE1 homolog (S. pombe)	0.022
IL11	interleukin 11	0.022
XIAP	X-linked inhibitor of apoptosis	0.022
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.022
TRIM24	tripartite motif containing 24	0.022	Human
ATN1	atrophin 1	0.021
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.021
CREBBP	CREB binding protein	0.021
ZNF529	zinc finger protein 529	0.021
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.021
WDR48	WD repeat domain 48	0.021
CHN2	chimerin (chimaerin) 2	0.021
TREM1	triggering receptor expressed on myeloid cells 1	0.021
IL1R2	interleukin 1 receptor, type II	0.021
SOX11	SRY (sex determining region Y)-box 11	0.021
IL10	interleukin 10	0.021
CCR7	chemokine (C-C motif) receptor 7	0.021
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.021
TIA1	TIA1 cytotoxic granule-associated RNA binding protein	0.021
UBXN2A	UBX domain protein 2A	0.021
NLRC4	NLR family, CARD domain containing 4	0.021
C1orf93	chromosome 1 open reading frame 93	0.020
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.020
TGFB2	transforming growth factor, beta 2	0.020	Human
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.020
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.020
RBM23	RNA binding motif protein 23	0.020
UBD	ubiquitin D	0.020
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.020	Fly
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.020
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.020
SRPK1	SRSF protein kinase 1	0.020	Yeast
MPRIP	myosin phosphatase Rho interacting protein	0.020
KIF4A	kinesin family member 4A	0.020
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.020
CENPE	centromere protein E, 312kDa	0.020
CXCL11	chemokine (C-X-C motif) ligand 11	0.020
ZNF638	zinc finger protein 638	0.020
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.020
PYDC2	pyrin domain containing 2	0.020
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.020
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.019
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.019
CMIP	c-Maf-inducing protein	0.019
DLG2	discs, large homolog 2 (Drosophila)	0.019
LMO4	LIM domain only 4	0.019
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.019
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.019
FZD8	frizzled homolog 8 (Drosophila)	0.019
WDYHV1	WDYHV motif containing 1	0.018
RHOXF2	Rhox homeobox family, member 2	0.018
IL1A	interleukin 1, alpha	0.018	Human
C20orf20	chromosome 20 open reading frame 20	0.018
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.018
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.018
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.018
TPM4	tropomyosin 4	0.018
IRS1	insulin receptor substrate 1	0.018
EVC2	Ellis van Creveld syndrome 2	0.018
PTK2	PTK2 protein tyrosine kinase 2	0.018
PIAS4	protein inhibitor of activated STAT, 4	0.018
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.018	Human
TRAF2	TNF receptor-associated factor 2	0.018
APOL3	apolipoprotein L, 3	0.018
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.018
RANBP2	RAN binding protein 2	0.018
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.018
DARC	Duffy blood group, chemokine receptor	0.018
VAV2	vav 2 guanine nucleotide exchange factor	0.017
SOX21	SRY (sex determining region Y)-box 21	0.017
INSR	insulin receptor	0.017
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	0.017
JAK2	Janus kinase 2	0.017	Rat
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.017
CHD4	chromodomain helicase DNA binding protein 4	0.017
SOD2	superoxide dismutase 2, mitochondrial	0.017
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.017
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.017
MED13	mediator complex subunit 13	0.017
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.017
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.017
IGF2R	insulin-like growth factor 2 receptor	0.017
IL21R	interleukin 21 receptor	0.017
EREG	epiregulin	0.017
DST	dystonin	0.017
TGFA	transforming growth factor, alpha	0.017
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.017
SCRIB	scribbled homolog (Drosophila)	0.017
BIRC2	baculoviral IAP repeat containing 2	0.017
COL2A1	collagen, type II, alpha 1	0.017
NRG1	neuregulin 1	0.017
CD14	CD14 molecule	0.017
MYST2	MYST histone acetyltransferase 2	0.017
PKN1	protein kinase N1	0.017
RAD50	RAD50 homolog (S. cerevisiae)	0.016
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.016
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.016
GJD2	gap junction protein, delta 2, 36kDa	0.016
TTC14	tetratricopeptide repeat domain 14	0.016
PPME1	protein phosphatase methylesterase 1	0.016
FBLIM1	filamin binding LIM protein 1	0.016	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.016
IL12RB2	interleukin 12 receptor, beta 2	0.016
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.016
ITGB7	integrin, beta 7	0.016
HOXC8	homeobox C8	0.016
GBP4	guanylate binding protein 4	0.016
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.016
MAPK8	mitogen-activated protein kinase 8	0.016
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.016
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.016
MYOZ1	myozenin 1	0.016
CXXC5	CXXC finger protein 5	0.016
WNT2	wingless-type MMTV integration site family member 2	0.016
CCL19	chemokine (C-C motif) ligand 19	0.015
THOC2	THO complex 2	0.015
GAB2	GRB2-associated binding protein 2	0.015
SOX7	SRY (sex determining region Y)-box 7	0.015
NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	0.015
FHL1	four and a half LIM domains 1	0.015
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.015
PKP3	plakophilin 3	0.015
TRIO	triple functional domain (PTPRF interacting)	0.015
MAPK14	mitogen-activated protein kinase 14	0.015	Mouse Worm
FANCD2	Fanconi anemia, complementation group D2	0.015
EDN1	endothelin 1	0.015
ZMYM4	zinc finger, MYM-type 4	0.015
TRIP10	thyroid hormone receptor interactor 10	0.015
C16orf74	chromosome 16 open reading frame 74	0.015
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.015
NME1-NME2	NME1-NME2 readthrough	0.015
CCL22	chemokine (C-C motif) ligand 22	0.015	Human
GLRX3	glutaredoxin 3	0.015
TNS4	tensin 4	0.015
FADD	Fas (TNFRSF6)-associated via death domain	0.015
KYNU	kynureninase	0.015
ZNF420	zinc finger protein 420	0.015
DNM2	dynamin 2	0.015
SOCS1	suppressor of cytokine signaling 1	0.015
SH3GL1	SH3-domain GRB2-like 1	0.015
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.015
SERTAD4	SERTA domain containing 4	0.014
RGS16	regulator of G-protein signaling 16	0.014
CEP55	centrosomal protein 55kDa	0.014
IRF4	interferon regulatory factor 4	0.014
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.014
MAPT	microtubule-associated protein tau	0.014
SH3RF1	SH3 domain containing ring finger 1	0.014
IL1F9	interleukin 1 family, member 9	0.014	Human
PDPN	podoplanin	0.014
TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	0.014
DUSP9	dual specificity phosphatase 9	0.014
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.014
SPRY4	sprouty homolog 4 (Drosophila)	0.014
ZC3H12A	zinc finger CCCH-type containing 12A	0.014
ZNF304	zinc finger protein 304	0.014
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.014
MED14	mediator complex subunit 14	0.014
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.014
GDNF	glial cell derived neurotrophic factor	0.014
CBX1	chromobox homolog 1	0.014
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.014
CKS2	CDC28 protein kinase regulatory subunit 2	0.014
S100A2	S100 calcium binding protein A2	0.014
SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.014
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.014
MKL2	MKL/myocardin-like 2	0.014
CCRL2	chemokine (C-C motif) receptor-like 2	0.014
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.014
SORBS3	sorbin and SH3 domain containing 3	0.014
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.014
PI3	peptidase inhibitor 3, skin-derived	0.014
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.014
PTPRE	protein tyrosine phosphatase, receptor type, E	0.014
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.014
E2F3	E2F transcription factor 3	0.014
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.014
FOXF1	forkhead box F1	0.014
MYO6	myosin VI	0.014
DBNL	drebrin-like	0.014	Human
POU3F3	POU class 3 homeobox 3	0.014	Human
POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	0.014
MAGEA2	melanoma antigen family A, 2	0.014
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.014
NCOA3	nuclear receptor coactivator 3	0.014
EPOR	erythropoietin receptor	0.014
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.014
LUC7L3	LUC7-like 3 (S. cerevisiae)	0.013
ECM1	extracellular matrix protein 1	0.013
TOP1	topoisomerase (DNA) I	0.013
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.013
GAB1	GRB2-associated binding protein 1	0.013
MYLK	myosin light chain kinase	0.013
SBF1	SET binding factor 1	0.013
PRRC2C	proline-rich coiled-coil 2C	0.013
EDAR	ectodysplasin A receptor	0.013
TNRC6A	trinucleotide repeat containing 6A	0.013
HM13	histocompatibility (minor) 13	0.013
RNF11	ring finger protein 11	0.013
FAS	Fas (TNF receptor superfamily, member 6)	0.013
EIF5B	eukaryotic translation initiation factor 5B	0.013
SOX1	SRY (sex determining region Y)-box 1	0.013
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.013
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.013
FBXL15	F-box and leucine-rich repeat protein 15	0.013
DOCK8	dedicator of cytokinesis 8	0.013
ARHGAP5	Rho GTPase activating protein 5	0.013
LAMP3	lysosomal-associated membrane protein 3	0.013
ZNF558	zinc finger protein 558	0.013	Human
HCP5	HLA complex P5	0.013
ITSN1	intersectin 1 (SH3 domain protein)	0.013
HDGF	hepatoma-derived growth factor	0.013
MBL2	mannose-binding lectin (protein C) 2, soluble	0.013
VCL	vinculin	0.013
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.013
MAP1S	microtubule-associated protein 1S	0.013
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.013
TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	0.013
ATP5J2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2	0.013
RBBP7	retinoblastoma binding protein 7	0.013
RARA	retinoic acid receptor, alpha	0.013
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.013
CCR3	chemokine (C-C motif) receptor 3	0.013
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.013
WNT3A	wingless-type MMTV integration site family, member 3A	0.013
TARBP2	TAR (HIV-1) RNA binding protein 2	0.013
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.013
DUSP23	dual specificity phosphatase 23	0.013
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.013
STK36	serine/threonine kinase 36	0.013
EPHA2	EPH receptor A2	0.013
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.012
FAM190B	family with sequence similarity 190, member B	0.012
TPP2	tripeptidyl peptidase II	0.012
GPSM2	G-protein signaling modulator 2	0.012
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.012
RBM12B	RNA binding motif protein 12B	0.012
IL15RA	interleukin 15 receptor, alpha	0.012
DTX3L	deltex 3-like (Drosophila)	0.012
IL18RAP	interleukin 18 receptor accessory protein	0.012
UBASH3B	ubiquitin associated and SH3 domain containing B	0.012
GLI1	GLI family zinc finger 1	0.012
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.012
CUL7	cullin 7	0.012
MSR1	macrophage scavenger receptor 1	0.012
ATM	ataxia telangiectasia mutated	0.012
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.012
ZNF432	zinc finger protein 432	0.012
NLK	nemo-like kinase	0.012
RNF181	ring finger protein 181	0.012
SH2D2A	SH2 domain containing 2A	0.012
MED24	mediator complex subunit 24	0.012
NRP2	neuropilin 2	0.012
CXCR6	chemokine (C-X-C motif) receptor 6	0.012
GTF3A	general transcription factor IIIA	0.012
TP53BP1	tumor protein p53 binding protein 1	0.012
ZNF571	zinc finger protein 571	0.012
AVEN	apoptosis, caspase activation inhibitor	0.012
PRKD2	protein kinase D2	0.012
GOLGA8B	golgin A8 family, member B	0.012
MGA	MAX gene associated	0.012
BRAP	BRCA1 associated protein	0.012
IGFBP4	insulin-like growth factor binding protein 4	0.012
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.012
PTPRF	protein tyrosine phosphatase, receptor type, F	0.012
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.012
PID1	phosphotyrosine interaction domain containing 1	0.012
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.012
PTAFR	platelet-activating factor receptor	0.012
CHERP	calcium homeostasis endoplasmic reticulum protein	0.012
RHOC	ras homolog gene family, member C	0.012
CTNNBIP1	catenin, beta interacting protein 1	0.012
FPR3	formyl peptide receptor 3	0.012
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.012
TERT	telomerase reverse transcriptase	0.012
RAI1	retinoic acid induced 1	0.012
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.012
SGPL1	sphingosine-1-phosphate lyase 1	0.012
PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.012
GHR	growth hormone receptor	0.012
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.012
IFIH1	interferon induced with helicase C domain 1	0.012	Human
ACVR1B	activin A receptor, type IB	0.012	Human
KRT14	keratin 14	0.012
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.012
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.012
SH2D1A	SH2 domain containing 1A	0.012
MAP7D1	MAP7 domain containing 1	0.012
S100A7	S100 calcium binding protein A7	0.012
RSF1	remodeling and spacing factor 1	0.012
USP37	ubiquitin specific peptidase 37	0.012
CSF3	colony stimulating factor 3 (granulocyte)	0.012
IRAK1	interleukin-1 receptor-associated kinase 1	0.012
TBX2	T-box 2	0.012
OBSL1	obscurin-like 1	0.012
GLIS2	GLIS family zinc finger 2	0.012
TRIM33	tripartite motif containing 33	0.012	Human
C5orf55	chromosome 5 open reading frame 55	0.011
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.011
NRP1	neuropilin 1	0.011
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.011
ASB2	ankyrin repeat and SOCS box containing 2	0.011
FERMT2	fermitin family member 2	0.011
C1orf63	chromosome 1 open reading frame 63	0.011
SH2B2	SH2B adaptor protein 2	0.011
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.011
ZNF354A	zinc finger protein 354A	0.011	Human
CLDN1	claudin 1	0.011
SLFN12	schlafen family member 12	0.011
PPP4C	protein phosphatase 4, catalytic subunit	0.011
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.011	Fly
HERC5	hect domain and RLD 5	0.011
ZBED5	zinc finger, BED-type containing 5	0.011
LHX1	LIM homeobox 1	0.011
OTP	orthopedia homeobox	0.011
ADAMDEC1	ADAM-like, decysin 1	0.011
FN1	fibronectin 1	0.011
CARD11	caspase recruitment domain family, member 11	0.011
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.011
JAK3	Janus kinase 3	0.011
NLRP3	NLR family, pyrin domain containing 3	0.011	Human
NKX3-1	NK3 homeobox 1	0.011
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.011	Rat
BATF	basic leucine zipper transcription factor, ATF-like	0.011
ZNF180	zinc finger protein 180	0.011
HCK	hemopoietic cell kinase	0.011
CLEC7A	C-type lectin domain family 7, member A	0.011
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.011
BMP3	bone morphogenetic protein 3	0.011	Human
ZNF567	zinc finger protein 567	0.011
EYA2	eyes absent homolog 2 (Drosophila)	0.011
ZNF266	zinc finger protein 266	0.011
ZFP112	zinc finger protein 112 homolog (mouse)	0.011
VAV3	vav 3 guanine nucleotide exchange factor	0.011
UBXN7	UBX domain protein 7	0.011
TSC1	tuberous sclerosis 1	0.011
ZNF224	zinc finger protein 224	0.011
VNN1	vanin 1	0.011
ARHGAP9	Rho GTPase activating protein 9	0.011
PLXDC1	plexin domain containing 1	0.011
KRT1	keratin 1	0.011
HIC1	hypermethylated in cancer 1	0.011
CHD6	chromodomain helicase DNA binding protein 6	0.011
OLIG2	oligodendrocyte lineage transcription factor 2	0.011
FURIN	furin (paired basic amino acid cleaving enzyme)	0.011
CCL17	chemokine (C-C motif) ligand 17	0.011	Human
OSM	oncostatin M	0.011
SMS	spermine synthase	0.011
ACVR2A	activin A receptor, type IIA	0.011
C5AR1	complement component 5a receptor 1	0.011
ZMYM2	zinc finger, MYM-type 2	0.011
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.011
LDHB	lactate dehydrogenase B	0.011
IRF5	interferon regulatory factor 5	0.011
SOD3	superoxide dismutase 3, extracellular	0.011
SYNJ2	synaptojanin 2	0.011
PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	0.011
KIF21A	kinesin family member 21A	0.011
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.011
TFEC	transcription factor EC	0.011
OSBPL11	oxysterol binding protein-like 11	0.011
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.011
CSK	c-src tyrosine kinase	0.011
THBS1	thrombospondin 1	0.011
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.011
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.011
ZC3HC1	zinc finger, C3HC-type containing 1	0.011
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.010
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.010
SOX5	SRY (sex determining region Y)-box 5	0.010
EGR2	early growth response 2	0.010
FNBP1	formin binding protein 1	0.010
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.010
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.010
ACACA	acetyl-CoA carboxylase alpha	0.010
PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.010
FRZB	frizzled-related protein	0.010
IL19	interleukin 19	0.010
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.010
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.010
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.010
ADAM15	ADAM metallopeptidase domain 15	0.010
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.010
DUOX2	dual oxidase 2	0.010
IFI44	interferon-induced protein 44	0.010
ZNF569	zinc finger protein 569	0.010
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.010
LUC7L	LUC7-like (S. cerevisiae)	0.010
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.010
FRMD5	FERM domain containing 5	0.010
IL2RB	interleukin 2 receptor, beta	0.010
ZNF83	zinc finger protein 83	0.010
RB1	retinoblastoma 1	0.010
BAK1	BCL2-antagonist/killer 1	0.010
KRT2	keratin 2	0.010
PRKCA	protein kinase C, alpha	0.010
BNC1	basonuclin 1	0.010
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.010
FHOD1	formin homology 2 domain containing 1	0.010
ART4	ADP-ribosyltransferase 4 (Dombrock blood group)	0.010
XCL2	chemokine (C motif) ligand 2	0.010	Human
ZNF350	zinc finger protein 350	0.010
GPR84	G protein-coupled receptor 84	0.010
C19orf2	chromosome 19 open reading frame 2	0.010
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.010
CCDC6	coiled-coil domain containing 6	0.010
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.010