IMP
Process View
dendritic spine morphogenesis
The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dendritic spine morphogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| ACTG1 | actin, gamma 1 | 0.986 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.775 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.723 | ||
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.590 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.428 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.420 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.393 | ||
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.305 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.224 | ||
| KCNA1 | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 0.206 | ||
| TMSB4X | thymosin beta 4, X-linked | 0.202 | ||
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.201 | ||
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.192 | ||
| ACTB | actin, beta | 0.177 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.175 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.174 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.162 | ||
| SPRR2A | small proline-rich protein 2A | 0.131 | ||
| TUBA1A | tubulin, alpha 1a | 0.123 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.120 | ||
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.111 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.106 | ||
| KCNA4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.101 | ||
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 | 0.097 | ||
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 0.092 | ||
| MAPT | microtubule-associated protein tau | 0.090 | ||
| BAIAP2 | BAI1-associated protein 2 | 0.090 | ||
| BAI1 | brain-specific angiogenesis inhibitor 1 | 0.080 | ||
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | 0.078 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.076 | ||
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.069 | ||
| NLGN1 | neuroligin 1 | 0.068 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.066 | ||
| SENP1 | SUMO1/sentrin specific peptidase 1 | 0.064 | Fly | |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.063 | ||
| CDK5 | cyclin-dependent kinase 5 | 0.060 | Mouse | |
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.057 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.056 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.055 | ||
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.053 | ||
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.052 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.051 | ||
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.050 | ||
| BAI2 | brain-specific angiogenesis inhibitor 2 | 0.049 | ||
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | 0.049 | ||
| TUBA1C | tubulin, alpha 1c | 0.048 | ||
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.046 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.045 | ||
| SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.044 | ||
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.044 | Mouse | |
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.042 | ||
| TUBA1B | tubulin, alpha 1b | 0.041 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.041 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.038 | ||
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.038 | ||
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.038 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.037 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.037 | ||
| PFDN1 | prefoldin subunit 1 | 0.034 | ||
| RAB5B | RAB5B, member RAS oncogene family | 0.034 | ||
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.034 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.032 | ||
| CFL2 | cofilin 2 (muscle) | 0.032 | Human | |
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.031 | ||
| LIMK1 | LIM domain kinase 1 | 0.030 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.030 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.029 | ||
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.029 | ||
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.028 | ||
| ACLY | ATP citrate lyase | 0.028 | ||
| DLG2 | discs, large homolog 2 (Drosophila) | 0.027 | ||
| MAP1B | microtubule-associated protein 1B | 0.027 | ||
| AGPS | alkylglycerone phosphate synthase | 0.026 | ||
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.025 | ||
| DNM1L | dynamin 1-like | 0.025 | ||
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.025 | ||
| ASNA1 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 0.024 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.024 | ||
| BMI1 | BMI1 polycomb ring finger oncogene | 0.024 | ||
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.024 | ||
| NRXN1 | neurexin 1 | 0.024 | ||
| ALAS1 | aminolevulinate, delta-, synthase 1 | 0.023 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.023 | ||
| TRIP10 | thyroid hormone receptor interactor 10 | 0.023 | ||
| DAPK1 | death-associated protein kinase 1 | 0.023 | ||
| DSTN | destrin (actin depolymerizing factor) | 0.022 | Human | |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.022 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.022 | ||
| DCTN3 | dynactin 3 (p22) | 0.022 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.022 | ||
| EPHB2 | EPH receptor B2 | 0.021 | Mouse | |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.021 | ||
| H2AFY | H2A histone family, member Y | 0.021 | ||
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.021 | ||
| VIM | vimentin | 0.021 | ||
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.021 | ||
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.020 | ||
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 0.020 | ||
| OCRL | oculocerebrorenal syndrome of Lowe | 0.020 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.020 | ||
| ARRB2 | arrestin, beta 2 | 0.020 | ||
| AATK | apoptosis-associated tyrosine kinase | 0.019 | ||
| PLD1 | phospholipase D1, phosphatidylcholine-specific | 0.019 | ||
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.019 | ||
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta | 0.019 | ||
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.018 | ||
| CHGB | chromogranin B (secretogranin 1) | 0.018 | ||
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | 0.018 | ||
| C4orf43 | chromosome 4 open reading frame 43 | 0.018 | ||
| RHOA | ras homolog gene family, member A | 0.018 | ||
| RNF2 | ring finger protein 2 | 0.018 | ||
| CRIPT | cysteine-rich PDZ-binding protein | 0.018 | ||
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.018 | ||
| CABLES2 | Cdk5 and Abl enzyme substrate 2 | 0.017 | ||
| IDE | insulin-degrading enzyme | 0.017 | ||
| PFN1 | profilin 1 | 0.017 | ||
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.017 | ||
| USP11 | ubiquitin specific peptidase 11 | 0.017 | ||
| PALLD | palladin, cytoskeletal associated protein | 0.017 | ||
| DCTN1 | dynactin 1 | 0.016 | ||
| C8orf33 | chromosome 8 open reading frame 33 | 0.016 | ||
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.016 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.016 | ||
| C7orf25 | chromosome 7 open reading frame 25 | 0.016 | ||
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.016 | ||
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 | 0.016 | ||
| TMSB10 | thymosin beta 10 | 0.016 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.016 | ||
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.016 | ||
| SP100 | SP100 nuclear antigen | 0.016 | ||
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.015 | ||
| ARRB1 | arrestin, beta 1 | 0.015 | ||
| RAB35 | RAB35, member RAS oncogene family | 0.015 | ||
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.015 | ||
| EFS | embryonal Fyn-associated substrate | 0.015 | ||
| PLD2 | phospholipase D2 | 0.014 | ||
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 | 0.014 | ||
| HEMGN | hemogen | 0.014 | ||
| EID1 | EP300 interacting inhibitor of differentiation 1 | 0.014 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.014 | ||
| PTPLAD1 | protein tyrosine phosphatase-like A domain containing 1 | 0.014 | ||
| UNC119 | unc-119 homolog (C. elegans) | 0.014 | ||
| ARHGAP1 | Rho GTPase activating protein 1 | 0.014 | ||
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.014 | ||
| C1orf109 | chromosome 1 open reading frame 109 | 0.014 | ||
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 | 0.014 | Rat | |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 | 0.014 | ||
| TSEN2 | tRNA splicing endonuclease 2 homolog (S. cerevisiae) | 0.013 | ||
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.013 | ||
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.013 | ||
| DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 | 0.013 | ||
| SEPT2 | septin 2 | 0.013 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.013 | ||
| ARF5 | ADP-ribosylation factor 5 | 0.013 | ||
| CBX7 | chromobox homolog 7 | 0.013 | ||
| DCAF17 | DDB1 and CUL4 associated factor 17 | 0.013 | ||
| FBXO25 | F-box protein 25 | 0.013 | ||
| MARK1 | MAP/microtubule affinity-regulating kinase 1 | 0.013 | ||
| MBNL2 | muscleblind-like 2 (Drosophila) | 0.013 | ||
| DCTN4 | dynactin 4 (p62) | 0.013 | ||
| TJP1 | tight junction protein 1 (zona occludens 1) | 0.013 | ||
| ZNF235 | zinc finger protein 235 | 0.013 | ||
| ARF3 | ADP-ribosylation factor 3 | 0.013 | ||
| RARA | retinoic acid receptor, alpha | 0.013 | ||
| TRO | trophinin | 0.012 | ||
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.012 | ||
| SH3RF3 | SH3 domain containing ring finger 3 | 0.012 | ||
| XPO7 | exportin 7 | 0.012 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.012 | ||
| DLG3 | discs, large homolog 3 (Drosophila) | 0.012 | ||
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.012 | ||
| APP | amyloid beta (A4) precursor protein | 0.012 | ||
| CHN2 | chimerin (chimaerin) 2 | 0.012 | ||
| HSF2 | heat shock transcription factor 2 | 0.012 | ||
| SLC4A3 | solute carrier family 4, anion exchanger, member 3 | 0.012 | ||
| ESR1 | estrogen receptor 1 | 0.012 | ||
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.012 | ||
| MLL2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.012 | ||
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.012 | ||
| RBBP5 | retinoblastoma binding protein 5 | 0.012 | ||
| C18orf10 | chromosome 18 open reading frame 10 | 0.012 | ||
| DPP6 | dipeptidyl-peptidase 6 | 0.012 | ||
| TRAPPC1 | trafficking protein particle complex 1 | 0.012 | ||
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.012 | ||
| SETD1A | SET domain containing 1A | 0.012 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.012 | ||
| LAS1L | LAS1-like (S. cerevisiae) | 0.012 | ||
| BEGAIN | brain-enriched guanylate kinase-associated homolog (rat) | 0.011 | ||
| EZR | ezrin | 0.011 | ||
| RAB6B | RAB6B, member RAS oncogene family | 0.011 | ||
| KCNA5 | potassium voltage-gated channel, shaker-related subfamily, member 5 | 0.011 | ||
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.011 | ||
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 0.011 | ||
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.011 | ||
| RUNDC3A | RUN domain containing 3A | 0.011 | ||
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.011 | ||
| API5 | apoptosis inhibitor 5 | 0.011 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.011 | ||
| LPHN2 | latrophilin 2 | 0.011 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.011 | ||
| CDC42SE1 | CDC42 small effector 1 | 0.011 | ||
| FMNL2 | formin-like 2 | 0.011 | ||
| FRK | fyn-related kinase | 0.011 | ||
| DOCK3 | dedicator of cytokinesis 3 | 0.011 | ||
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | 0.011 | ||
| PHTF2 | putative homeodomain transcription factor 2 | 0.011 | ||
| SYP | synaptophysin | 0.011 | ||
| HPCAL4 | hippocalcin like 4 | 0.011 | ||
| MRPL44 | mitochondrial ribosomal protein L44 | 0.011 | ||
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.011 | ||
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 0.010 | ||
| CAMKV | CaM kinase-like vesicle-associated | 0.010 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.010 | ||
| CBX6 | chromobox homolog 6 | 0.010 | ||
| POLB | polymerase (DNA directed), beta | 0.010 | ||
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.010 | ||
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 0.010 | ||
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 | 0.010 | ||
| TUBB | tubulin, beta | 0.010 | ||
| NCKAP1 | NCK-associated protein 1 | 0.010 | ||
| KIAA0196 | KIAA0196 | 0.010 | ||
| PRSS23 | protease, serine, 23 | 0.010 | ||
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 0.010 | ||
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.010 | ||
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.010 | ||
| NUP188 | nucleoporin 188kDa | 0.010 | ||
| SCP2 | sterol carrier protein 2 | 0.010 | ||
| BCL2L1 | BCL2-like 1 | 0.010 |