IMP
Process View
thyroid hormone generation
The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "thyroid hormone generation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.997 | ||
| NKX2-1 | NK2 homeobox 1 | 0.664 | ||
| MEOX1 | mesenchyme homeobox 1 | 0.617 | ||
| MED10 | mediator complex subunit 10 | 0.535 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.257 | ||
| MED13 | mediator complex subunit 13 | 0.121 | ||
| ESR2 | estrogen receptor 2 (ER beta) | 0.117 | ||
| TBX5 | T-box 5 | 0.109 | ||
| PML | promyelocytic leukemia | 0.107 | ||
| DAXX | death-domain associated protein | 0.099 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.097 | ||
| MED29 | mediator complex subunit 29 | 0.077 | ||
| RUNX1 | runt-related transcription factor 1 | 0.075 | ||
| CDK8 | cyclin-dependent kinase 8 | 0.070 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.057 | Human | |
| KLF13 | Kruppel-like factor 13 | 0.051 | ||
| RARA | retinoic acid receptor, alpha | 0.048 | ||
| GATA2 | GATA binding protein 2 | 0.046 | Human | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.041 | ||
| SDC2 | syndecan 2 | 0.037 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.035 | ||
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 0.033 | ||
| TGS1 | trimethylguanosine synthase 1 | 0.032 | ||
| SP1 | Sp1 transcription factor | 0.031 | ||
| BBS1 | Bardet-Biedl syndrome 1 | 0.031 | ||
| PRRC2C | proline-rich coiled-coil 2C | 0.031 | ||
| WT1 | Wilms tumor 1 | 0.029 | ||
| CGB5 | chorionic gonadotropin, beta polypeptide 5 | 0.029 | ||
| S100A4 | S100 calcium binding protein A4 | 0.029 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.028 | ||
| CDK19 | cyclin-dependent kinase 19 | 0.026 | ||
| ZFPM1 | zinc finger protein, multitype 1 | 0.024 | ||
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.024 | ||
| FSHB | follicle stimulating hormone, beta polypeptide | 0.022 | ||
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 0.021 | ||
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.021 | ||
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.019 | ||
| TADA2A | transcriptional adaptor 2A | 0.019 | ||
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.019 | ||
| SFN | stratifin | 0.018 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.017 | ||
| TRRAP | transformation/transcription domain-associated protein | 0.017 | ||
| TBX1 | T-box 1 | 0.017 | ||
| TNPO1 | transportin 1 | 0.017 | ||
| RBBP5 | retinoblastoma binding protein 5 | 0.016 | ||
| HAND2 | heart and neural crest derivatives expressed 2 | 0.016 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.015 | ||
| MED14 | mediator complex subunit 14 | 0.015 | ||
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.015 | ||
| DHH | desert hedgehog | 0.015 | ||
| PAX2 | paired box 2 | 0.014 | Human | |
| PAX5 | paired box 5 | 0.014 | Human | |
| KLF1 | Kruppel-like factor 1 (erythroid) | 0.014 | ||
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.014 | ||
| MED24 | mediator complex subunit 24 | 0.014 | ||
| SIM2 | single-minded homolog 2 (Drosophila) | 0.014 | ||
| ALX4 | ALX homeobox 4 | 0.014 | ||
| KLHL35 | kelch-like 35 (Drosophila) | 0.013 | ||
| GOSR1 | golgi SNAP receptor complex member 1 | 0.013 | ||
| SFRP5 | secreted frizzled-related protein 5 | 0.013 | ||
| COL2A1 | collagen, type II, alpha 1 | 0.013 | ||
| HNF1B | HNF1 homeobox B | 0.012 | ||
| CYBRD1 | cytochrome b reductase 1 | 0.012 | ||
| RHAG | Rh-associated glycoprotein | 0.012 | ||
| RXRA | retinoid X receptor, alpha | 0.012 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.012 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.012 | ||
| SLC5A5 | solute carrier family 5 (sodium iodide symporter), member 5 | 0.012 | ||
| MED6 | mediator complex subunit 6 | 0.011 | ||
| HOXD13 | homeobox D13 | 0.011 | ||
| NKX2-8 | NK2 homeobox 8 | 0.011 | ||
| BHLHE23 | basic helix-loop-helix family, member e23 | 0.011 | ||
| FBXO45 | F-box protein 45 | 0.011 | ||
| HOXD1 | homeobox D1 | 0.011 | ||
| KCNJ5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.011 | ||
| GSTM4 | glutathione S-transferase mu 4 | 0.010 | ||
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.010 | ||
| LHX1 | LIM homeobox 1 | 0.010 | ||
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.010 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.010 | ||
| GATA4 | GATA binding protein 4 | 0.010 | Human | |
| ITM2B | integral membrane protein 2B | 0.010 |