IMP: Integrative Multi-species Prediction

Homo sapiens

48 genes annotated in human

Multi-species View

negative regulation of epithelial cell proliferation

GO:0050680

Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of epithelial cell proliferation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of epithelial cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
RARA	retinoic acid receptor, alpha	0.998
ESR1	estrogen receptor 1	0.996
TGFB1	transforming growth factor, beta 1	0.993
RXRA	retinoid X receptor, alpha	0.990	Human
CAV1	caveolin 1, caveolae protein, 22kDa	0.987	Mouse
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.963
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.961
TAL1	T-cell acute lymphocytic leukemia 1	0.929
EGFR	epidermal growth factor receptor	0.882
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.843
NCK2	NCK adaptor protein 2	0.830
NCOA1	nuclear receptor coactivator 1	0.811
NCOR2	nuclear receptor corepressor 2	0.793
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.752
CDK6	cyclin-dependent kinase 6	0.702
NCOA3	nuclear receptor coactivator 3	0.656
MED25	mediator complex subunit 25	0.652
RUNX1	runt-related transcription factor 1	0.567
CCND1	cyclin D1	0.562
GSK3B	glycogen synthase kinase 3 beta	0.558
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.520
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.491
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.482
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.431	Mouse
CCR5	chemokine (C-C motif) receptor 5	0.415	Human
FGF1	fibroblast growth factor 1 (acidic)	0.399
PAX3	paired box 3	0.391
FBXL12	F-box and leucine-rich repeat protein 12	0.391
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.370
IL2RB	interleukin 2 receptor, beta	0.351
SMAD2	SMAD family member 2	0.333
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.327
SMAD7	SMAD family member 7	0.310
CAV2	caveolin 2	0.307	Mouse
FSTL1	follistatin-like 1	0.304
AXIN1	axin 1	0.304
CCND3	cyclin D3	0.292
TCF4	transcription factor 4	0.275
MAGED1	melanoma antigen family D, 1	0.266
CDK4	cyclin-dependent kinase 4	0.263	Human
POU3F2	POU class 3 homeobox 2	0.263
POU5F1	POU class 5 homeobox 1	0.261
INSR	insulin receptor	0.250
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.247
S100B	S100 calcium binding protein B	0.239
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.237
KIF5B	kinesin family member 5B	0.228
JAK2	Janus kinase 2	0.219
YAP1	Yes-associated protein 1	0.216
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.209
HP	haptoglobin	0.208
STK3	serine/threonine kinase 3	0.207
HDAC4	histone deacetylase 4	0.206
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.204
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.200
TGFB3	transforming growth factor, beta 3	0.197
BTRC	beta-transducin repeat containing	0.187
LIN7C	lin-7 homolog C (C. elegans)	0.183
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.181
CCL5	chemokine (C-C motif) ligand 5	0.180
SDC2	syndecan 2	0.167
FBLN1	fibulin 1	0.166
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.163
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.156
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.154
COL3A1	collagen, type III, alpha 1	0.147
CREBBP	CREB binding protein	0.146
TIMP3	TIMP metallopeptidase inhibitor 3	0.145
NRP1	neuropilin 1	0.141
MAGED2	melanoma antigen family D, 2	0.140	Human
SMAD4	SMAD family member 4	0.136
PTEN	phosphatase and tensin homolog	0.136	Mouse
NCOR1	nuclear receptor corepressor 1	0.135
AR	androgen receptor	0.135	Mouse
TERF1	telomeric repeat binding factor (NIMA-interacting) 1	0.134
TERF2	telomeric repeat binding factor 2	0.134
TP53	tumor protein p53	0.134
IRF9	interferon regulatory factor 9	0.127
STAT5A	signal transducer and activator of transcription 5A	0.126	Human
FGFR2	fibroblast growth factor receptor 2	0.126	Rat
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.123
HIPK2	homeodomain interacting protein kinase 2	0.121
SMN1	survival of motor neuron 1, telomeric	0.121
ESRRG	estrogen-related receptor gamma	0.119
IRF4	interferon regulatory factor 4	0.118
ENG	endoglin	0.116
F2R	coagulation factor II (thrombin) receptor	0.113
BMPR1B	bone morphogenetic protein receptor, type IB	0.113
TGFBR1	transforming growth factor, beta receptor 1	0.112	Mouse
F11R	F11 receptor	0.111
PPP5C	protein phosphatase 5, catalytic subunit	0.108
EP300	E1A binding protein p300	0.108
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.107
CSNK1E	casein kinase 1, epsilon	0.107
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.106
PECAM1	platelet/endothelial cell adhesion molecule	0.103
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.102
CPE	carboxypeptidase E	0.098
SP1	Sp1 transcription factor	0.098
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.096
SKP1	S-phase kinase-associated protein 1	0.095
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.094
CALD1	caldesmon 1	0.092
LCAT	lecithin-cholesterol acyltransferase	0.090
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.089
JAK1	Janus kinase 1	0.087
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.087	Rat
PJA1	praja ring finger 1	0.087
CCNE1	cyclin E1	0.086
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.085
MEIS2	Meis homeobox 2	0.085
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.083
PTPRF	protein tyrosine phosphatase, receptor type, F	0.080	Human
CTGF	connective tissue growth factor	0.079
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.079	Mouse
AMOTL2	angiomotin like 2	0.078
CCL22	chemokine (C-C motif) ligand 22	0.078
HNF4A	hepatocyte nuclear factor 4, alpha	0.077	Human
MYLK2	myosin light chain kinase 2	0.076
STAG1	stromal antigen 1	0.076
APOC1	apolipoprotein C-I	0.075
STRADA	STE20-related kinase adaptor alpha	0.073
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.072
ADAM17	ADAM metallopeptidase domain 17	0.072
IL2RG	interleukin 2 receptor, gamma	0.071
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.070
LPXN	leupaxin	0.066
IL4R	interleukin 4 receptor	0.066
BMPR1A	bone morphogenetic protein receptor, type IA	0.065
CXCR6	chemokine (C-X-C motif) receptor 6	0.065	Human
FGFR1	fibroblast growth factor receptor 1	0.064
PARVA	parvin, alpha	0.063
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.062
FBXW11	F-box and WD repeat domain containing 11	0.062
ACVR1B	activin A receptor, type IB	0.062
HDAC7	histone deacetylase 7	0.062
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.062
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.062
PML	promyelocytic leukemia	0.061
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.060
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.058
MEF2A	myocyte enhancer factor 2A	0.058
GYPC	glycophorin C (Gerbich blood group)	0.058
A2M	alpha-2-macroglobulin	0.057
KRT8	keratin 8	0.056
FZD1	frizzled homolog 1 (Drosophila)	0.055
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.054
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.054
ILK	integrin-linked kinase	0.054
TTR	transthyretin	0.053
MEOX2	mesenchyme homeobox 2	0.053
PROX1	prospero homeobox 1	0.053
CTNND1	catenin (cadherin-associated protein), delta 1	0.053
IRS1	insulin receptor substrate 1	0.053
MYO6	myosin VI	0.052
EPRS	glutamyl-prolyl-tRNA synthetase	0.052
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.052
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.052
TSC1	tuberous sclerosis 1	0.051
LRP6	low density lipoprotein receptor-related protein 6	0.051	Mouse
FASLG	Fas ligand (TNF superfamily, member 6)	0.050
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.050
PPARG	peroxisome proliferator-activated receptor gamma	0.050	Human
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.050
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.050
PSEN1	presenilin 1	0.050
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.049
KIAA1377	KIAA1377	0.049
EDNRB	endothelin receptor type B	0.049
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.049
IGF1R	insulin-like growth factor 1 receptor	0.048
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.048
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.048
PRMT2	protein arginine methyltransferase 2	0.048
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.048
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.047
RARG	retinoic acid receptor, gamma	0.046
INADL	InaD-like (Drosophila)	0.046
BMP2	bone morphogenetic protein 2	0.046
WWTR1	WW domain containing transcription regulator 1	0.046
BRCA1	breast cancer 1, early onset	0.046
CCR2	chemokine (C-C motif) receptor 2	0.046	Human
CAPN1	calpain 1, (mu/I) large subunit	0.045
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.045
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.045
MAPT	microtubule-associated protein tau	0.044
HR	hairless homolog (mouse)	0.044
RARS	arginyl-tRNA synthetase	0.044
CCDC6	coiled-coil domain containing 6	0.044
QARS	glutaminyl-tRNA synthetase	0.044
WNT2	wingless-type MMTV integration site family member 2	0.043
GRB10	growth factor receptor-bound protein 10	0.043
HTRA1	HtrA serine peptidase 1	0.043
GJA1	gap junction protein, alpha 1, 43kDa	0.043
APP	amyloid beta (A4) precursor protein	0.043
LIN7A	lin-7 homolog A (C. elegans)	0.043
SALL2	sal-like 2 (Drosophila)	0.043
FGF7	fibroblast growth factor 7	0.043
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.042
COL2A1	collagen, type II, alpha 1	0.042
IFNG	interferon, gamma	0.042
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.042
SFRP1	secreted frizzled-related protein 1	0.042
EGR1	early growth response 1	0.042
RB1	retinoblastoma 1	0.041	Mouse
TBX2	T-box 2	0.041
FOXO1	forkhead box O1	0.041
JUB	jub, ajuba homolog (Xenopus laevis)	0.041
PGR	progesterone receptor	0.041
GHR	growth hormone receptor	0.041
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.040	Human
TBX5	T-box 5	0.040
HIC1	hypermethylated in cancer 1	0.040
MYOD1	myogenic differentiation 1	0.040
COL5A1	collagen, type V, alpha 1	0.040
GLIS2	GLIS family zinc finger 2	0.039
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.039
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.039
CDH5	cadherin 5, type 2 (vascular endothelium)	0.039
FGF10	fibroblast growth factor 10	0.039
NCOA6	nuclear receptor coactivator 6	0.039
CXCL9	chemokine (C-X-C motif) ligand 9	0.038
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.038
THBS1	thrombospondin 1	0.038
SMAD6	SMAD family member 6	0.038
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.037
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.037
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.037
SFRP2	secreted frizzled-related protein 2	0.036
IGFBP5	insulin-like growth factor binding protein 5	0.036
EPS8	epidermal growth factor receptor pathway substrate 8	0.036
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.036
DCN	decorin	0.036
LRRK2	leucine-rich repeat kinase 2	0.036
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.036
SOX9	SRY (sex determining region Y)-box 9	0.036	Human Mouse
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.035
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.035
SPDEF	SAM pointed domain containing ets transcription factor	0.035
TTC35	tetratricopeptide repeat domain 35	0.035
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.035
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.035
CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.034
APC	adenomatous polyposis coli	0.034	Mouse
IL12RB2	interleukin 12 receptor, beta 2	0.034
TWIST1	twist homolog 1 (Drosophila)	0.034
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.034
FERMT2	fermitin family member 2	0.034
TGFB2	transforming growth factor, beta 2	0.034
MYLK	myosin light chain kinase	0.034
STAT2	signal transducer and activator of transcription 2, 113kDa	0.034	Human
CXCL12	chemokine (C-X-C motif) ligand 12	0.034
HES1	hairy and enhancer of split 1, (Drosophila)	0.034
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.034
FGF2	fibroblast growth factor 2 (basic)	0.033
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.033
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.033
FKBP1A	FK506 binding protein 1A, 12kDa	0.033
LAMB1	laminin, beta 1	0.033
NOG	noggin	0.033
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.032
NOTCH1	notch 1	0.032
PKP4	plakophilin 4	0.032
SLIT2	slit homolog 2 (Drosophila)	0.032
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.032
SMAD3	SMAD family member 3	0.032
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.032
TBX21	T-box 21	0.032
FOXC1	forkhead box C1	0.031
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.031
CLDN5	claudin 5	0.031
FOXF1	forkhead box F1	0.031
FN1	fibronectin 1	0.031
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.031
MED1	mediator complex subunit 1	0.031
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.031
CCNDBP1	cyclin D-type binding-protein 1	0.031
PEX1	peroxisomal biogenesis factor 1	0.031
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.031
BGN	biglycan	0.030
STAT5B	signal transducer and activator of transcription 5B	0.030	Human
MARCKSL1	MARCKS-like 1	0.030
PTPRD	protein tyrosine phosphatase, receptor type, D	0.030	Human
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.030
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.030
DLC1	deleted in liver cancer 1	0.030
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.030
SLIT3	slit homolog 3 (Drosophila)	0.029
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.029
SOCS3	suppressor of cytokine signaling 3	0.029
LHFP	lipoma HMGIC fusion partner	0.029
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.029
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.029
GAS1	growth arrest-specific 1	0.029	Mouse
CDX2	caudal type homeobox 2	0.029
CD2	CD2 molecule	0.029
VEGFC	vascular endothelial growth factor C	0.029
RARB	retinoic acid receptor, beta	0.029
NRIP1	nuclear receptor interacting protein 1	0.028
GATA3	GATA binding protein 3	0.028
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.028
TXNRD1	thioredoxin reductase 1	0.028
JAG1	jagged 1	0.028
LMO2	LIM domain only 2 (rhombotin-like 1)	0.028
CD40LG	CD40 ligand	0.027
SH2B1	SH2B adaptor protein 1	0.027
FAS	Fas (TNF receptor superfamily, member 6)	0.027
FGFR3	fibroblast growth factor receptor 3	0.027	Mouse Rat
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.027
STRADB	STE20-related kinase adaptor beta	0.027
BLZF1	basic leucine zipper nuclear factor 1	0.027
EPAS1	endothelial PAS domain protein 1	0.026
KLF13	Kruppel-like factor 13	0.026
APIP	APAF1 interacting protein	0.026
CUL1	cullin 1	0.026
CRABP1	cellular retinoic acid binding protein 1	0.026
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.026
MGP	matrix Gla protein	0.026
TCF7	transcription factor 7 (T-cell specific, HMG-box)	0.026
SMAD5	SMAD family member 5	0.026
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.026
CXXC5	CXXC finger protein 5	0.026
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.026
ANGPTL2	angiopoietin-like 2	0.026
EFNB3	ephrin-B3	0.026
ELL	elongation factor RNA polymerase II	0.026
SLAMF7	SLAM family member 7	0.026
CD34	CD34 molecule	0.026
SNAI2	snail homolog 2 (Drosophila)	0.026
SOX17	SRY (sex determining region Y)-box 17	0.026	Human
WNT3A	wingless-type MMTV integration site family, member 3A	0.026
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.025
EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.025
SDPR	serum deprivation response	0.025
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.025
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.025	Human
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.025
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.025
VCAN	versican	0.025
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.025
GPM6B	glycoprotein M6B	0.025
SMAD1	SMAD family member 1	0.025
SOX4	SRY (sex determining region Y)-box 4	0.025	Human
MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	0.024
APOC3	apolipoprotein C-III	0.024
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.024
PMEPA1	prostate transmembrane protein, androgen induced 1	0.024
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.024
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.024
INHBB	inhibin, beta B	0.024
S1PR1	sphingosine-1-phosphate receptor 1	0.024
PRKCDBP	protein kinase C, delta binding protein	0.024
AEBP1	AE binding protein 1	0.024
ACD	adrenocortical dysplasia homolog (mouse)	0.024
SPOP	speckle-type POZ protein	0.024
BMP4	bone morphogenetic protein 4	0.024	Mouse
EDNRA	endothelin receptor type A	0.024
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.024
CDK2	cyclin-dependent kinase 2	0.024
COL18A1	collagen, type XVIII, alpha 1	0.024
TGFBR3	transforming growth factor, beta receptor III	0.024	Human Mouse
CDK8	cyclin-dependent kinase 8	0.024
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.024
ZFYVE9	zinc finger, FYVE domain containing 9	0.023
COL1A1	collagen, type I, alpha 1	0.023
LTK	leukocyte receptor tyrosine kinase	0.023
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.023
PDGFC	platelet derived growth factor C	0.023
ZFPM1	zinc finger protein, multitype 1	0.023
GEMIN6	gem (nuclear organelle) associated protein 6	0.023
C5orf13	chromosome 5 open reading frame 13	0.023
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.023
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.023	Human
INHBA	inhibin, beta A	0.023
HAP1	huntingtin-associated protein 1	0.023
SOCS1	suppressor of cytokine signaling 1	0.023
HIPK3	homeodomain interacting protein kinase 3	0.023
SKIL	SKI-like oncogene	0.023
WT1	Wilms tumor 1	0.022
SPTBN1	spectrin, beta, non-erythrocytic 1	0.022
WDR83	WD repeat domain 83	0.022
GATA2	GATA binding protein 2	0.022	Human
ACVR2B	activin A receptor, type IIB	0.022
SGSM2	small G protein signaling modulator 2	0.022
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.022
NCOA2	nuclear receptor coactivator 2	0.022
RBL1	retinoblastoma-like 1 (p107)	0.022
SYT11	synaptotagmin XI	0.022
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.022
ARHGAP5	Rho GTPase activating protein 5	0.022
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.022
EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	0.022
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.022
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.022
KDM1A	lysine (K)-specific demethylase 1A	0.022
MECOM	MDS1 and EVI1 complex locus	0.021
CTBP1	C-terminal binding protein 1	0.021
GDF6	growth differentiation factor 6	0.021	Human
SOX18	SRY (sex determining region Y)-box 18	0.021	Human
APOD	apolipoprotein D	0.021
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.021
CCL3	chemokine (C-C motif) ligand 3	0.021
IL21R	interleukin 21 receptor	0.021
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.021
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.021
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.021
SFRP4	secreted frizzled-related protein 4	0.021
HDAC9	histone deacetylase 9	0.021
FZD7	frizzled homolog 7 (Drosophila)	0.021
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.021
CAPN6	calpain 6	0.021
TBX1	T-box 1	0.020
E2F1	E2F transcription factor 1	0.020
ERBB2IP	erbb2 interacting protein	0.020
NFIB	nuclear factor I/B	0.020	Mouse
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.020
TRIL	TLR4 interactor with leucine-rich repeats	0.020
STAP2	signal transducing adaptor family member 2	0.020
CCL4	chemokine (C-C motif) ligand 4	0.020
C16orf53	chromosome 16 open reading frame 53	0.020
PRPH	peripherin	0.020
CCR7	chemokine (C-C motif) receptor 7	0.020	Human
ZBTB16	zinc finger and BTB domain containing 16	0.020
RASL12	RAS-like, family 12	0.020
MYH11	myosin, heavy chain 11, smooth muscle	0.020
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.020
FHL2	four and a half LIM domains 2	0.020
PEX13	peroxisomal biogenesis factor 13	0.020
CHD3	chromodomain helicase DNA binding protein 3	0.020
HDAC3	histone deacetylase 3	0.020
JUP	junction plakoglobin	0.020
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.020
RAI14	retinoic acid induced 14	0.020
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.020
DDR1	discoidin domain receptor tyrosine kinase 1	0.020
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.020
PPAP2B	phosphatidic acid phosphatase type 2B	0.019
PPARA	peroxisome proliferator-activated receptor alpha	0.019	Human
GORAB	golgin, RAB6-interacting	0.019
HAND2	heart and neural crest derivatives expressed 2	0.019
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.019
MTA2	metastasis associated 1 family, member 2	0.019
USP8	ubiquitin specific peptidase 8	0.019
MSX1	msh homeobox 1	0.019
IRS2	insulin receptor substrate 2	0.019
NFYA	nuclear transcription factor Y, alpha	0.019
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.019
SPON1	spondin 1, extracellular matrix protein	0.019
RXRB	retinoid X receptor, beta	0.019	Human
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.019
RXRG	retinoid X receptor, gamma	0.019	Human
VPS25	vacuolar protein sorting 25 homolog (S. cerevisiae)	0.019	Fly
SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	0.019
CCR8	chemokine (C-C motif) receptor 8	0.019	Human
DAXX	death-domain associated protein	0.019
CDK11B	cyclin-dependent kinase 11B	0.019
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.019
EMCN	endomucin	0.019
FBXW2	F-box and WD repeat domain containing 2	0.019
IL4	interleukin 4	0.019
FGF18	fibroblast growth factor 18	0.019
PER1	period homolog 1 (Drosophila)	0.019
TF	transferrin	0.019
IGFBP7	insulin-like growth factor binding protein 7	0.019
TCF21	transcription factor 21	0.019
APOA2	apolipoprotein A-II	0.018
ZMYND11	zinc finger, MYND-type containing 11	0.018
RUNX2	runt-related transcription factor 2	0.018
TMEM47	transmembrane protein 47	0.018
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.018
MTA3	metastasis associated 1 family, member 3	0.018
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.018
IL11	interleukin 11	0.018
SOX2	SRY (sex determining region Y)-box 2	0.018
PLG	plasminogen	0.018
SRPX	sushi-repeat containing protein, X-linked	0.018
TRO	trophinin	0.018	Human
FGA	fibrinogen alpha chain	0.018
PCGF2	polycomb group ring finger 2	0.018
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.018
PALM	paralemmin	0.018
CCR4	chemokine (C-C motif) receptor 4	0.018	Human
ZFPM2	zinc finger protein, multitype 2	0.018
GATA5	GATA binding protein 5	0.018	Human
KANK3	KN motif and ankyrin repeat domains 3	0.018
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.018
CTTN	cortactin	0.018
ITIH5	inter-alpha (globulin) inhibitor H5	0.018
EDN3	endothelin 3	0.018
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.018
CLEC7A	C-type lectin domain family 7, member A	0.018
COL4A1	collagen, type IV, alpha 1	0.018
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.018
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.018
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.018
CTNNBIP1	catenin, beta interacting protein 1	0.018
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.018
DLK1	delta-like 1 homolog (Drosophila)	0.018
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.018
IL10	interleukin 10	0.018
ARHGAP29	Rho GTPase activating protein 29	0.017
FZD8	frizzled homolog 8 (Drosophila)	0.017
THRAP3	thyroid hormone receptor associated protein 3	0.017
CNTNAP2	contactin associated protein-like 2	0.017
NMI	N-myc (and STAT) interactor	0.017
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.017
PLK2	polo-like kinase 2	0.017
RBP4	retinol binding protein 4, plasma	0.017
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.017
DST	dystonin	0.017
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.017
RGS5	regulator of G-protein signaling 5	0.017
PRKCA	protein kinase C, alpha	0.017
SOX11	SRY (sex determining region Y)-box 11	0.017	Human
CADM4	cell adhesion molecule 4	0.017
GUCY1A3	guanylate cyclase 1, soluble, alpha 3	0.017
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.017
FOXA1	forkhead box A1	0.017
PRRX1	paired related homeobox 1	0.017
SHPRH	SNF2 histone linker PHD RING helicase	0.017
POSTN	periostin, osteoblast specific factor	0.017
MDK	midkine (neurite growth-promoting factor 2)	0.017
SOX1	SRY (sex determining region Y)-box 1	0.017	Human
STK4	serine/threonine kinase 4	0.017
CCL2	chemokine (C-C motif) ligand 2	0.017
FAM110C	family with sequence similarity 110, member C	0.017
GPC3	glypican 3	0.017
TNFRSF25	tumor necrosis factor receptor superfamily, member 25	0.017
PCDH7	protocadherin 7	0.017
CXCL13	chemokine (C-X-C motif) ligand 13	0.017
COL8A1	collagen, type VIII, alpha 1	0.017
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.017
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.017
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.017
GIMAP4	GTPase, IMAP family member 4	0.017
CD86	CD86 molecule	0.017
BCL6	B-cell CLL/lymphoma 6	0.017
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.017
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.017
ZMYND8	zinc finger, MYND-type containing 8	0.017
MAVS	mitochondrial antiviral signaling protein	0.017
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.017
FZD2	frizzled homolog 2 (Drosophila)	0.016
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.016
NBN	nibrin	0.016
DLG3	discs, large homolog 3 (Drosophila)	0.016
LTBP4	latent transforming growth factor beta binding protein 4	0.016
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.016
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.016
TP73	tumor protein p73	0.016
PDE10A	phosphodiesterase 10A	0.016
IL2RA	interleukin 2 receptor, alpha	0.016
CLDN4	claudin 4	0.016
PTPRG	protein tyrosine phosphatase, receptor type, G	0.016
CDK19	cyclin-dependent kinase 19	0.016
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.016
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.016
ITGB5	integrin, beta 5	0.016
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.016
RNASE6	ribonuclease, RNase A family, k6	0.016
IL5RA	interleukin 5 receptor, alpha	0.016
PTRF	polymerase I and transcript release factor	0.016
RAD50	RAD50 homolog (S. cerevisiae)	0.016
ITFG1	integrin alpha FG-GAP repeat containing 1	0.016
PMP22	peripheral myelin protein 22	0.016
CYBB	cytochrome b-245, beta polypeptide	0.016
LEF1	lymphoid enhancer-binding factor 1	0.016
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.016
CDX1	caudal type homeobox 1	0.016
PHLDB2	pleckstrin homology-like domain, family B, member 2	0.016
EPHA4	EPH receptor A4	0.016
DIO3	deiodinase, iodothyronine, type III	0.016
MUC1	mucin 1, cell surface associated	0.016
EPHB3	EPH receptor B3	0.016
COL6A1	collagen, type VI, alpha 1	0.016
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.016
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.016
SCP2	sterol carrier protein 2	0.016
SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	0.016
CCND2	cyclin D2	0.016
CXCR4	chemokine (C-X-C motif) receptor 4	0.016	Human
APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.016
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.016
PTCH1	patched 1	0.016
FAM46A	family with sequence similarity 46, member A	0.016
HRG	histidine-rich glycoprotein	0.016
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.016
HSPA1B	heat shock 70kDa protein 1B	0.016
FAM110A	family with sequence similarity 110, member A	0.016
CHMP6	chromatin modifying protein 6	0.016	Fly
SEPP1	selenoprotein P, plasma, 1	0.015
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.015
JPH3	junctophilin 3	0.015
CXCR3	chemokine (C-X-C motif) receptor 3	0.015
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.015
VWF	von Willebrand factor	0.015
BCL6B	B-cell CLL/lymphoma 6, member B	0.015
FAM101B	family with sequence similarity 101, member B	0.015
ALX4	ALX homeobox 4	0.015
DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	0.015
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.015
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.015
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.015
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.015
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.015
CCR9	chemokine (C-C motif) receptor 9	0.015	Human
LBP	lipopolysaccharide binding protein	0.015
KNG1	kininogen 1	0.015
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.015
TBXA2R	thromboxane A2 receptor	0.015
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.015
TPP1	tripeptidyl peptidase I	0.015
SHE	Src homology 2 domain containing E	0.015
TMEM173	transmembrane protein 173	0.015
IGF1	insulin-like growth factor 1 (somatomedin C)	0.015
UROD	uroporphyrinogen decarboxylase	0.015
DRD4	dopamine receptor D4	0.015
FOXG1	forkhead box G1	0.015
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.015
DPYSL3	dihydropyrimidinase-like 3	0.015
MN1	meningioma (disrupted in balanced translocation) 1	0.015
LAMA4	laminin, alpha 4	0.015
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.015
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.015
GEMIN7	gem (nuclear organelle) associated protein 7	0.015
CHD4	chromodomain helicase DNA binding protein 4	0.015
TCF15	transcription factor 15 (basic helix-loop-helix)	0.015
GPRC5B	G protein-coupled receptor, family C, group 5, member B	0.015
FLRT2	fibronectin leucine rich transmembrane protein 2	0.015
TCF12	transcription factor 12	0.015
HOXD12	homeobox D12	0.015
RGS1	regulator of G-protein signaling 1	0.015
BICD1	bicaudal D homolog 1 (Drosophila)	0.015
AQP5	aquaporin 5	0.015
IL9R	interleukin 9 receptor	0.015
NKX3-2	NK3 homeobox 2	0.015
GPR18	G protein-coupled receptor 18	0.015
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.015	Human
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.015
RYK	RYK receptor-like tyrosine kinase	0.015
ETV1	ets variant 1	0.015
LECT1	leukocyte cell derived chemotaxin 1	0.015
LAMC3	laminin, gamma 3	0.015
MMS22L	MMS22-like, DNA repair protein	0.015
RBP1	retinol binding protein 1, cellular	0.015
PRKCZ	protein kinase C, zeta	0.015
EPHA3	EPH receptor A3	0.014
TUFM	Tu translation elongation factor, mitochondrial	0.014
WFDC2	WAP four-disulfide core domain 2	0.014
TLN1	talin 1	0.014
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.014
ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	0.014
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.014
CLU	clusterin	0.014
RUNX3	runt-related transcription factor 3	0.014	Mouse
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.014
PROCR	protein C receptor, endothelial	0.014
LPAR1	lysophosphatidic acid receptor 1	0.014
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.014
HDAC5	histone deacetylase 5	0.014
VIL1	villin 1	0.014
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.014
NGFR	nerve growth factor receptor	0.014
SLMAP	sarcolemma associated protein	0.014
MFAP4	microfibrillar-associated protein 4	0.014
OLIG2	oligodendrocyte lineage transcription factor 2	0.014
OXA1L	oxidase (cytochrome c) assembly 1-like	0.014
ACVR1	activin A receptor, type I	0.014
INHA	inhibin, alpha	0.014
NRP2	neuropilin 2	0.014
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.014
OSMR	oncostatin M receptor	0.014
CD6	CD6 molecule	0.014
PITX2	paired-like homeodomain 2	0.014
NUAK1	NUAK family, SNF1-like kinase, 1	0.014
NEUROD1	neurogenic differentiation 1	0.014
NOS3	nitric oxide synthase 3 (endothelial cell)	0.014
WNT4	wingless-type MMTV integration site family, member 4	0.014
CD59	CD59 molecule, complement regulatory protein	0.014
APLNR	apelin receptor	0.014
NPAS2	neuronal PAS domain protein 2	0.014
FOXD3	forkhead box D3	0.014
PTH1R	parathyroid hormone 1 receptor	0.014
ITGB8	integrin, beta 8	0.014
CSNK1D	casein kinase 1, delta	0.014
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.014
THBS2	thrombospondin 2	0.014	Human
PCM1	pericentriolar material 1	0.014
YBX1	Y box binding protein 1	0.014
TNXB	tenascin XB	0.014
FOXF2	forkhead box F2	0.014
COL17A1	collagen, type XVII, alpha 1	0.014
F13A1	coagulation factor XIII, A1 polypeptide	0.014
PTK7	PTK7 protein tyrosine kinase 7	0.014
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.014
SELL	selectin L	0.014
ZCCHC24	zinc finger, CCHC domain containing 24	0.014
PSORS1C2	psoriasis susceptibility 1 candidate 2	0.014
FBXL7	F-box and leucine-rich repeat protein 7	0.014
TBX3	T-box 3	0.014
MED14	mediator complex subunit 14	0.014
FGB	fibrinogen beta chain	0.014
FLT4	fms-related tyrosine kinase 4	0.014
SEC16A	SEC16 homolog A (S. cerevisiae)	0.014
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.014
MMRN2	multimerin 2	0.014
PIBF1	progesterone immunomodulatory binding factor 1	0.014
AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	0.014
MTA1	metastasis associated 1	0.014
KANK2	KN motif and ankyrin repeat domains 2	0.014
HDC	histidine decarboxylase	0.014
PCDH17	protocadherin 17	0.014
CYBRD1	cytochrome b reductase 1	0.014
FBXO4	F-box protein 4	0.014
TRAP1	TNF receptor-associated protein 1	0.014
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.014
IL10RA	interleukin 10 receptor, alpha	0.013
POT1	protection of telomeres 1 homolog (S. pombe)	0.013
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.013
SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	0.013
CISH	cytokine inducible SH2-containing protein	0.013
RBL2	retinoblastoma-like 2 (p130)	0.013
HOXD9	homeobox D9	0.013
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.013
ANGPT1	angiopoietin 1	0.013
RHAG	Rh-associated glycoprotein	0.013
MYH10	myosin, heavy chain 10, non-muscle	0.013
PTHLH	parathyroid hormone-like hormone	0.013
SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	0.013
ALX3	ALX homeobox 3	0.013
MCAM	melanoma cell adhesion molecule	0.013
EFNB1	ephrin-B1	0.013
CRLF1	cytokine receptor-like factor 1	0.013
CCL19	chemokine (C-C motif) ligand 19	0.013
HGFAC	HGF activator	0.013
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.013
CP	ceruloplasmin (ferroxidase)	0.013
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.013
FBLN2	fibulin 2	0.013
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.013
GZMK	granzyme K (granzyme 3; tryptase II)	0.013
BMP7	bone morphogenetic protein 7	0.013	Human
EXT1	exostosin 1	0.013
MID1	midline 1 (Opitz/BBB syndrome)	0.013
PLTP	phospholipid transfer protein	0.013
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.013
GATAD1	GATA zinc finger domain containing 1	0.013
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.013
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.013