IMP: Integrative Multi-species Prediction

Homo sapiens

46 genes annotated in human

positive regulation of protein import into nucleus

Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of protein import into nucleus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of protein import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD2	SMAD family member 2	0.999	Human
SMAD3	SMAD family member 3	0.995
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.990	Human
EGFR	epidermal growth factor receptor	0.958
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.944	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.933
SMAD1	SMAD family member 1	0.914	Human
IL8	interleukin 8	0.912
IL1R1	interleukin 1 receptor, type I	0.865
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.811
SMAD7	SMAD family member 7	0.799	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.797	Human
KPNB1	karyopherin (importin) beta 1	0.792	Fly
ESR1	estrogen receptor 1	0.791
PSEN1	presenilin 1	0.747
CCL4	chemokine (C-C motif) ligand 4	0.715	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.714
CCR5	chemokine (C-C motif) receptor 5	0.695
TNF	tumor necrosis factor	0.675
BTRC	beta-transducin repeat containing	0.667	Fly
MYD88	myeloid differentiation primary response gene (88)	0.665
CUL1	cullin 1	0.655
BMP2	bone morphogenetic protein 2	0.654	Human
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.630
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.615
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.610
FLNA	filamin A, alpha	0.588
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.571
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.569
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.550
CXCL3	chemokine (C-X-C motif) ligand 3	0.549
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.545
IL1B	interleukin 1, beta	0.523
FKBP1A	FK506 binding protein 1A, 12kDa	0.483
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.464
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.459
YAP1	Yes-associated protein 1	0.441
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.439	Human
FLNB	filamin B, beta	0.430	Human
TGFBR1	transforming growth factor, beta receptor 1	0.423
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.422
NCOA1	nuclear receptor coactivator 1	0.403
BMPR1B	bone morphogenetic protein receptor, type IB	0.388	Human
WASL	Wiskott-Aldrich syndrome-like	0.384
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.381
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.375	Human
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.370
RNF31	ring finger protein 31	0.365
MAVS	mitochondrial antiviral signaling protein	0.362
IQGAP1	IQ motif containing GTPase activating protein 1	0.356
APP	amyloid beta (A4) precursor protein	0.308
SRPK2	SRSF protein kinase 2	0.307	Yeast
TGFB1	transforming growth factor, beta 1	0.306
CCL20	chemokine (C-C motif) ligand 20	0.295	Human
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.284
RACGAP1	Rac GTPase activating protein 1	0.278
APC	adenomatous polyposis coli	0.273
ANGPT2	angiopoietin 2	0.271
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.242
MYH9	myosin, heavy chain 9, non-muscle	0.235
CBX5	chromobox homolog 5	0.234
LAT	linker for activation of T cells	0.223
GSK3B	glycogen synthase kinase 3 beta	0.222
RXRA	retinoid X receptor, alpha	0.219
SKIL	SKI-like oncogene	0.216
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.213
IRF2	interferon regulatory factor 2	0.211
LRRK2	leucine-rich repeat kinase 2	0.204
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.204
SP1	Sp1 transcription factor	0.203
DSG2	desmoglein 2	0.202
TLR2	toll-like receptor 2	0.198
DSP	desmoplakin	0.194
HIPK3	homeodomain interacting protein kinase 3	0.194
CCL2	chemokine (C-C motif) ligand 2	0.191	Human
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.179
IL6	interleukin 6 (interferon, beta 2)	0.176
CREBBP	CREB binding protein	0.173
TRAF1	TNF receptor-associated factor 1	0.172
FOXD3	forkhead box D3	0.171
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.170
SH2D4A	SH2 domain containing 4A	0.162
ENG	endoglin	0.158
RARA	retinoic acid receptor, alpha	0.157
SNAI1	snail homolog 1 (Drosophila)	0.157
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.157
CCR1	chemokine (C-C motif) receptor 1	0.155
TRIM25	tripartite motif containing 25	0.152
CTNND1	catenin (cadherin-associated protein), delta 1	0.147
TGFB3	transforming growth factor, beta 3	0.146	Mouse
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.139
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.138
ZFYVE9	zinc finger, FYVE domain containing 9	0.136
IDE	insulin-degrading enzyme	0.134
ICAM1	intercellular adhesion molecule 1	0.133
FSTL1	follistatin-like 1	0.133
NCOR1	nuclear receptor corepressor 1	0.132
GDF5	growth differentiation factor 5	0.129	Human
CCL8	chemokine (C-C motif) ligand 8	0.126	Human
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.124
BCL2A1	BCL2-related protein A1	0.123
CDK8	cyclin-dependent kinase 8	0.119
NOG	noggin	0.118
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.113
ANGPT1	angiopoietin 1	0.100
ZNF84	zinc finger protein 84	0.100
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.100
BAIAP2	BAI1-associated protein 2	0.094
CUL4A	cullin 4A	0.091
CXCL5	chemokine (C-X-C motif) ligand 5	0.091
IL1R2	interleukin 1 receptor, type II	0.087
SMAD4	SMAD family member 4	0.086	Human Mouse
CXCL11	chemokine (C-X-C motif) ligand 11	0.085
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.082
ACTN1	actinin, alpha 1	0.077
PLAUR	plasminogen activator, urokinase receptor	0.076
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.076	Rat
KIF23	kinesin family member 23	0.075	Fly
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.074
WDR48	WD repeat domain 48	0.074
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.074
CTNNBIP1	catenin, beta interacting protein 1	0.073
HOXA9	homeobox A9	0.072
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.072
WIPF1	WAS/WASL interacting protein family, member 1	0.069
LRP6	low density lipoprotein receptor-related protein 6	0.068	Human
NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	0.067
BMP4	bone morphogenetic protein 4	0.067
MBOAT7	membrane bound O-acyltransferase domain containing 7	0.065
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.064
BBS10	Bardet-Biedl syndrome 10	0.064
RIPK2	receptor-interacting serine-threonine kinase 2	0.063
TRADD	TNFRSF1A-associated via death domain	0.063
PRKG1	protein kinase, cGMP-dependent, type I	0.062
PRRC2C	proline-rich coiled-coil 2C	0.062
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.061	Rat
FAF1	Fas (TNFRSF6) associated factor 1	0.061
INHBA	inhibin, beta A	0.061
BIRC3	baculoviral IAP repeat containing 3	0.059
CTSS	cathepsin S	0.058
CCL3	chemokine (C-C motif) ligand 3	0.057	Human
DLG4	discs, large homolog 4 (Drosophila)	0.057
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.057	Human
TPM4	tropomyosin 4	0.056
ITGB4	integrin, beta 4	0.055
IFIH1	interferon induced with helicase C domain 1	0.055	Human
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.054
FZD1	frizzled homolog 1 (Drosophila)	0.054
ITGB1BP3	integrin beta 1 binding protein 3	0.054
ACTN4	actinin, alpha 4	0.053
IRAK1	interleukin-1 receptor-associated kinase 1	0.052
SOX2	SRY (sex determining region Y)-box 2	0.052
MED24	mediator complex subunit 24	0.051
CXCL9	chemokine (C-X-C motif) ligand 9	0.051
CCL22	chemokine (C-C motif) ligand 22	0.051	Human
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.051
NCF2	neutrophil cytosolic factor 2	0.051
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.050	Human
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.050
XIRP1	xin actin-binding repeat containing 1	0.050
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.050
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.049	Human
HDAC6	histone deacetylase 6	0.049
PDLIM7	PDZ and LIM domain 7 (enigma)	0.049
LY96	lymphocyte antigen 96	0.048
TMEM173	transmembrane protein 173	0.047
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.046
IGF1R	insulin-like growth factor 1 receptor	0.046
SOCS3	suppressor of cytokine signaling 3	0.046
SPRR2A	small proline-rich protein 2A	0.045
FAS	Fas (TNF receptor superfamily, member 6)	0.045
CCR7	chemokine (C-C motif) receptor 7	0.044
DCAF8	DDB1 and CUL4 associated factor 8	0.044
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.044
JUP	junction plakoglobin	0.043
CD83	CD83 molecule	0.043
ATF7IP	activating transcription factor 7 interacting protein	0.043
IL10	interleukin 10	0.042
VASP	vasodilator-stimulated phosphoprotein	0.042
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.042
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.041
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.040
CH25H	cholesterol 25-hydroxylase	0.040
CYLD	cylindromatosis (turban tumor syndrome)	0.040
CXXC5	CXXC finger protein 5	0.039
CXCL10	chemokine (C-X-C motif) ligand 10	0.039
LBR	lamin B receptor	0.039
CFLAR	CASP8 and FADD-like apoptosis regulator	0.039
TRIM21	tripartite motif containing 21	0.039
FBXW11	F-box and WD repeat domain containing 11	0.039	Fly
CCR4	chemokine (C-C motif) receptor 4	0.039
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.038
ATM	ataxia telangiectasia mutated	0.038
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.038
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.038
IGF2R	insulin-like growth factor 2 receptor	0.037
GRB2	growth factor receptor-bound protein 2	0.037
EXOC5	exocyst complex component 5	0.037
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.036
CHN2	chimerin (chimaerin) 2	0.036
THBS1	thrombospondin 1	0.035
MAGEA2	melanoma antigen family A, 2	0.035
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.035
YY1	YY1 transcription factor	0.035
ACVR2B	activin A receptor, type IIB	0.034
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.034
SMAD6	SMAD family member 6	0.034	Human
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.034
LMNA	lamin A/C	0.034
ZMYND11	zinc finger, MYND-type containing 11	0.034
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.034
C20orf20	chromosome 20 open reading frame 20	0.034
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.034
DBN1	drebrin 1	0.034	Human
MSC	musculin	0.033
ZNF140	zinc finger protein 140	0.033	Human
CCL13	chemokine (C-C motif) ligand 13	0.033	Human
AATF	apoptosis antagonizing transcription factor	0.032
SOX11	SRY (sex determining region Y)-box 11	0.032
LMO4	LIM domain only 4	0.031
IL1A	interleukin 1, alpha	0.031	Human
CCR3	chemokine (C-C motif) receptor 3	0.031
ZNF420	zinc finger protein 420	0.031
NRP1	neuropilin 1	0.031
CCL1	chemokine (C-C motif) ligand 1	0.031	Human
SOCS1	suppressor of cytokine signaling 1	0.031
IL4R	interleukin 4 receptor	0.030
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.030
HMG20A	high mobility group 20A	0.030
FBXL15	F-box and leucine-rich repeat protein 15	0.029
DPP4	dipeptidyl-peptidase 4	0.029
NUP153	nucleoporin 153kDa	0.029
CARD11	caspase recruitment domain family, member 11	0.029
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.029
BAK1	BCL2-antagonist/killer 1	0.029
SSRP1	structure specific recognition protein 1	0.029
VCL	vinculin	0.029
FHL1	four and a half LIM domains 1	0.029
TCF4	transcription factor 4	0.028
CAPRIN2	caprin family member 2	0.028
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.028
FZD7	frizzled homolog 7 (Drosophila)	0.028
IRF4	interferon regulatory factor 4	0.028
AR	androgen receptor	0.028
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.028
USP15	ubiquitin specific peptidase 15	0.028
TLN1	talin 1	0.028
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.027
TRIM37	tripartite motif containing 37	0.027
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.027
CENPE	centromere protein E, 312kDa	0.027
TNPO1	transportin 1	0.027
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.027
CCL7	chemokine (C-C motif) ligand 7	0.027	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.027
FERMT2	fermitin family member 2	0.026
VAV2	vav 2 guanine nucleotide exchange factor	0.026
XPO1	exportin 1 (CRM1 homolog, yeast)	0.026
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.026
GLIS2	GLIS family zinc finger 2	0.026
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.026
RANBP9	RAN binding protein 9	0.026
RGS1	regulator of G-protein signaling 1	0.026
CUL3	cullin 3	0.026
PARP12	poly (ADP-ribose) polymerase family, member 12	0.025
WEE1	WEE1 homolog (S. pombe)	0.025
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.025
RAG1	recombination activating gene 1	0.025
ZNF260	zinc finger protein 260	0.025
ATN1	atrophin 1	0.025
PYDC2	pyrin domain containing 2	0.025
NRG1	neuregulin 1	0.025
PTK2	PTK2 protein tyrosine kinase 2	0.024
FZD8	frizzled homolog 8 (Drosophila)	0.024
DARC	Duffy blood group, chemokine receptor	0.024
IFNG	interferon, gamma	0.024
GHR	growth hormone receptor	0.024
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.024
CXCL13	chemokine (C-X-C motif) ligand 13	0.024
SMAD5	SMAD family member 5	0.024	Human
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.024
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.023
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.023
SOX21	SRY (sex determining region Y)-box 21	0.023
INSR	insulin receptor	0.023
WNT3A	wingless-type MMTV integration site family, member 3A	0.023
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.023
TRIP10	thyroid hormone receptor interactor 10	0.023
ITGB7	integrin, beta 7	0.023
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.023
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.023
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.023
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.022
TREM1	triggering receptor expressed on myeloid cells 1	0.022
ACVR1	activin A receptor, type I	0.022	Human
DLG2	discs, large homolog 2 (Drosophila)	0.022
IL21R	interleukin 21 receptor	0.022
CBX1	chromobox homolog 1	0.022
CDK12	cyclin-dependent kinase 12	0.022
UBXN7	UBX domain protein 7	0.022
GAB2	GRB2-associated binding protein 2	0.022
CKAP5	cytoskeleton associated protein 5	0.022
GPSM2	G-protein signaling modulator 2	0.022
CAND1	cullin-associated and neddylation-dissociated 1	0.022
NLRP3	NLR family, pyrin domain containing 3	0.022	Human
PIAS4	protein inhibitor of activated STAT, 4	0.022
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.022
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.022
HIPK1	homeodomain interacting protein kinase 1	0.021
ZNF585A	zinc finger protein 585A	0.021
CCNB1	cyclin B1	0.021
ESR2	estrogen receptor 2 (ER beta)	0.021
SPOP	speckle-type POZ protein	0.021
PSEN2	presenilin 2 (Alzheimer disease 4)	0.021
CRIPAK	cysteine-rich PAK1 inhibitor	0.021
C1orf93	chromosome 1 open reading frame 93	0.021
TGFB2	transforming growth factor, beta 2	0.021	Human
MEST	mesoderm specific transcript homolog (mouse)	0.021
TGFA	transforming growth factor, alpha	0.020
KIF4A	kinesin family member 4A	0.020
PLEK	pleckstrin	0.020
AQP9	aquaporin 9	0.020
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.020
TNRC6C	trinucleotide repeat containing 6C	0.020
C19orf2	chromosome 19 open reading frame 2	0.020
MYST2	MYST histone acetyltransferase 2	0.020
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.020
RGS16	regulator of G-protein signaling 16	0.020
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.020
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.020
CNN2	calponin 2	0.020
UBXN1	UBX domain protein 1	0.020
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.020
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.020
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.020
ZNF432	zinc finger protein 432	0.020
EBI3	Epstein-Barr virus induced 3	0.020
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.020
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.019
IL1F9	interleukin 1 family, member 9	0.019	Human
ZNF569	zinc finger protein 569	0.019
SFN	stratifin	0.019
SELE	selectin E	0.019
EIF5B	eukaryotic translation initiation factor 5B	0.019
DUSP23	dual specificity phosphatase 23	0.019
PID1	phosphotyrosine interaction domain containing 1	0.019
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.019
TFPI2	tissue factor pathway inhibitor 2	0.019
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.019
SALL2	sal-like 2 (Drosophila)	0.019
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.019
SCRIB	scribbled homolog (Drosophila)	0.019
HOXC8	homeobox C8	0.019
SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.018
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.018
MED13	mediator complex subunit 13	0.018
KYNU	kynureninase	0.018
CHERP	calcium homeostasis endoplasmic reticulum protein	0.018
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.018
MBL2	mannose-binding lectin (protein C) 2, soluble	0.018
DDB1	damage-specific DNA binding protein 1, 127kDa	0.018
MUC1	mucin 1, cell surface associated	0.018
EDAR	ectodysplasin A receptor	0.018
CCL19	chemokine (C-C motif) ligand 19	0.018
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.018
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.018
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.018
LASP1	LIM and SH3 protein 1	0.018
TRAF2	TNF receptor-associated factor 2	0.017
DDR2	discoidin domain receptor tyrosine kinase 2	0.017
FHL3	four and a half LIM domains 3	0.017
EREG	epiregulin	0.017
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.017	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.017
TBX2	T-box 2	0.017
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.017
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.017
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.017
RNF11	ring finger protein 11	0.017
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.017
DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	0.017
MAPK8	mitogen-activated protein kinase 8	0.017
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.017
MTMR4	myotubularin related protein 4	0.017
ACP5	acid phosphatase 5, tartrate resistant	0.017
ECT2	epithelial cell transforming sequence 2 oncogene	0.017	Mouse
ZNF83	zinc finger protein 83	0.016
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.016
IL7R	interleukin 7 receptor	0.016
RBM12B	RNA binding motif protein 12B	0.016
CCL11	chemokine (C-C motif) ligand 11	0.016	Human
TCF12	transcription factor 12	0.016
MED14	mediator complex subunit 14	0.016
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.016
FBLIM1	filamin binding LIM protein 1	0.016	Human
SKP1	S-phase kinase-associated protein 1	0.016
NUP98	nucleoporin 98kDa	0.016
AXIN1	axin 1	0.016
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.016
ACVR1B	activin A receptor, type IB	0.016	Human
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.016
KAT5	K(lysine) acetyltransferase 5	0.016
KDM1A	lysine (K)-specific demethylase 1A	0.016
FOXF2	forkhead box F2	0.016
FPR3	formyl peptide receptor 3	0.016
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.016
PI3	peptidase inhibitor 3, skin-derived	0.015
CDK11B	cyclin-dependent kinase 11B	0.015
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.015
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.015
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.015
RTP4	receptor (chemosensory) transporter protein 4	0.015
MYO6	myosin VI	0.015
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.015
PTPRE	protein tyrosine phosphatase, receptor type, E	0.015
IPO7	importin 7	0.015
RHOC	ras homolog gene family, member C	0.015
STAT4	signal transducer and activator of transcription 4	0.015
BIRC6	baculoviral IAP repeat containing 6	0.015
IER3	immediate early response 3	0.015
NPAS3	neuronal PAS domain protein 3	0.015
SOX10	SRY (sex determining region Y)-box 10	0.015
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.015
STAP2	signal transducing adaptor family member 2	0.015
CCRL2	chemokine (C-C motif) receptor-like 2	0.015
IRF7	interferon regulatory factor 7	0.015
WDR26	WD repeat domain 26	0.015
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.015
RHOU	ras homolog gene family, member U	0.015
USP42	ubiquitin specific peptidase 42	0.015
ZNF304	zinc finger protein 304	0.014
ZNF12	zinc finger protein 12	0.014
STK36	serine/threonine kinase 36	0.014
SH3RF3	SH3 domain containing ring finger 3	0.014
DNM2	dynamin 2	0.014
NCOA3	nuclear receptor coactivator 3	0.014
PARP9	poly (ADP-ribose) polymerase family, member 9	0.014
PITX2	paired-like homeodomain 2	0.014
COL2A1	collagen, type II, alpha 1	0.014
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.014
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.014
POU3F3	POU class 3 homeobox 3	0.014	Human
C5AR1	complement component 5a receptor 1	0.014
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.014
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.014
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.014
FRZB	frizzled-related protein	0.014
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.014	Fly
MKL2	MKL/myocardin-like 2	0.014
GPR84	G protein-coupled receptor 84	0.014
ZNF567	zinc finger protein 567	0.014
PLAU	plasminogen activator, urokinase	0.014
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.014
BMP3	bone morphogenetic protein 3	0.014	Human
CSF1	colony stimulating factor 1 (macrophage)	0.014
PDPN	podoplanin	0.014
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.014
HIC1	hypermethylated in cancer 1	0.014
BTK	Bruton agammaglobulinemia tyrosine kinase	0.014
CCDC6	coiled-coil domain containing 6	0.013
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.013
IL4	interleukin 4	0.013
C3AR1	complement component 3a receptor 1	0.013
TFEC	transcription factor EC	0.013
WNT2	wingless-type MMTV integration site family member 2	0.013
CRHR2	corticotropin releasing hormone receptor 2	0.013
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.013
TLR6	toll-like receptor 6	0.013	Human
TRIL	TLR4 interactor with leucine-rich repeats	0.013
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.013	Fly
PBK	PDZ binding kinase	0.013
RBMS3	RNA binding motif, single stranded interacting protein 3	0.013
PFN1	profilin 1	0.013
DOCK8	dedicator of cytokinesis 8	0.013
GPR109B	G protein-coupled receptor 109B	0.013
BMP7	bone morphogenetic protein 7	0.013	Human
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.013
SGPL1	sphingosine-1-phosphate lyase 1	0.013
CSF3	colony stimulating factor 3 (granulocyte)	0.013
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.013
JAK3	Janus kinase 3	0.013
KIF18A	kinesin family member 18A	0.013
BZW2	basic leucine zipper and W2 domains 2	0.013
PDLIM4	PDZ and LIM domain 4	0.013
LAMP3	lysosomal-associated membrane protein 3	0.013
SET	SET nuclear oncogene	0.013
LHX1	LIM homeobox 1	0.013
CRP	C-reactive protein, pentraxin-related	0.013
NRP2	neuropilin 2	0.013
TLR3	toll-like receptor 3	0.013
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.013
PRKCD	protein kinase C, delta	0.013
STAT1	signal transducer and activator of transcription 1, 91kDa	0.013
EDN1	endothelin 1	0.013
TNS4	tensin 4	0.013
IL2RB	interleukin 2 receptor, beta	0.013
CENPF	centromere protein F, 350/400kDa (mitosin)	0.013
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.013
NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	0.012
GDNF	glial cell derived neurotrophic factor	0.012
FCAR	Fc fragment of IgA, receptor for	0.012
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.012
EEF2K	eukaryotic elongation factor-2 kinase	0.012
MYOZ1	myozenin 1	0.012
USP9X	ubiquitin specific peptidase 9, X-linked	0.012
HDGF	hepatoma-derived growth factor	0.012
IRAK2	interleukin-1 receptor-associated kinase 2	0.012
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.012
ZNF337	zinc finger protein 337	0.012
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.012
ZC3HC1	zinc finger, C3HC-type containing 1	0.012
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.012
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.012
DST	dystonin	0.012
CNN1	calponin 1, basic, smooth muscle	0.012
TRO	trophinin	0.012
CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	0.012
EYA2	eyes absent homolog 2 (Drosophila)	0.012
SOX7	SRY (sex determining region Y)-box 7	0.012
HERC5	hect domain and RLD 5	0.012
KIF5B	kinesin family member 5B	0.012
GJD2	gap junction protein, delta 2, 36kDa	0.012
ITGB8	integrin, beta 8	0.012
PRKD2	protein kinase D2	0.012
TTK	TTK protein kinase	0.012
HMGA1	high mobility group AT-hook 1	0.012
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.012
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.012
IL2RA	interleukin 2 receptor, alpha	0.012
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.012
IGFBP5	insulin-like growth factor binding protein 5	0.012
LRP12	low density lipoprotein receptor-related protein 12	0.012
IRF5	interferon regulatory factor 5	0.012
TOP1	topoisomerase (DNA) I	0.012
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.012
FZD2	frizzled homolog 2 (Drosophila)	0.012
CMA1	chymase 1, mast cell	0.012
IQGAP2	IQ motif containing GTPase activating protein 2	0.012
WWOX	WW domain containing oxidoreductase	0.012
KPNA6	karyopherin alpha 6 (importin alpha 7)	0.012
PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	0.012
SLAMF7	SLAM family member 7	0.012
HBEGF	heparin-binding EGF-like growth factor	0.012
CMIP	c-Maf-inducing protein	0.012
PTAFR	platelet-activating factor receptor	0.012
NLRC5	NLR family, CARD domain containing 5	0.012	Human
CCNA2	cyclin A2	0.012
STAT2	signal transducer and activator of transcription 2, 113kDa	0.012
SLIT2	slit homolog 2 (Drosophila)	0.012
CXCR5	chemokine (C-X-C motif) receptor 5	0.012
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.012
ZNF571	zinc finger protein 571	0.012
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.012	Rat
TG	thyroglobulin	0.012
VAV3	vav 3 guanine nucleotide exchange factor	0.012
MED25	mediator complex subunit 25	0.012
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.011
BATF	basic leucine zipper transcription factor, ATF-like	0.011
DOCK1	dedicator of cytokinesis 1	0.011
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.011
ADAMDEC1	ADAM-like, decysin 1	0.011
RAI1	retinoic acid induced 1	0.011
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.011
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.011
CCL23	chemokine (C-C motif) ligand 23	0.011	Human
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.011
ADAM15	ADAM metallopeptidase domain 15	0.011
LY86	lymphocyte antigen 86	0.011
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	0.011
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.011
FADD	Fas (TNFRSF6)-associated via death domain	0.011
EVC2	Ellis van Creveld syndrome 2	0.011
IPO8	importin 8	0.011
TGFBR3	transforming growth factor, beta receptor III	0.011
TRIM22	tripartite motif containing 22	0.011
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	0.011
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.011
CCL17	chemokine (C-C motif) ligand 17	0.011	Human
ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	0.011
ADARB1	adenosine deaminase, RNA-specific, B1	0.011
PSME4	proteasome (prosome, macropain) activator subunit 4	0.011
NFYA	nuclear transcription factor Y, alpha	0.011
TARBP2	TAR (HIV-1) RNA binding protein 2	0.011
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.011
PTK6	PTK6 protein tyrosine kinase 6	0.011
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.011
VCAM1	vascular cell adhesion molecule 1	0.011
CCR9	chemokine (C-C motif) receptor 9	0.011
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.011
PKP3	plakophilin 3	0.011
MYLK	myosin light chain kinase	0.011
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.011
RC3H2	ring finger and CCCH-type domains 2	0.011
APOL6	apolipoprotein L, 6	0.011
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.011
PIWIL1	piwi-like 1 (Drosophila)	0.011
VNN2	vanin 2	0.011
SYNPO2	synaptopodin 2	0.011
IFI44	interferon-induced protein 44	0.011
IL2	interleukin 2	0.011
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.011
COL4A4	collagen, type IV, alpha 4	0.011
PTPRD	protein tyrosine phosphatase, receptor type, D	0.011
ZNF223	zinc finger protein 223	0.011
ACVR2A	activin A receptor, type IIA	0.011
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.011
FBXO30	F-box protein 30	0.011
SF3B14	splicing factor 3B, 14 kDa subunit	0.011
TPSD1	tryptase delta 1	0.011
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.011
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.011
CCL21	chemokine (C-C motif) ligand 21	0.011
HOXA1	homeobox A1	0.010
NKX3-1	NK3 homeobox 1	0.010
IGF2	insulin-like growth factor 2 (somatomedin A)	0.010	Human
ILK	integrin-linked kinase	0.010
WRN	Werner syndrome, RecQ helicase-like	0.010
BIRC2	baculoviral IAP repeat containing 2	0.010
IL11	interleukin 11	0.010
SH2B1	SH2B adaptor protein 1	0.010
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.010
ANGPT4	angiopoietin 4	0.010
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.010
NOV	nephroblastoma overexpressed gene	0.010
ZFPM2	zinc finger protein, multitype 2	0.010
ERBB2IP	erbb2 interacting protein	0.010
PTCH1	patched 1	0.010
LAPTM5	lysosomal protein transmembrane 5	0.010
XCL2	chemokine (C motif) ligand 2	0.010	Human
S100A7	S100 calcium binding protein A7	0.010
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.010
KIF21A	kinesin family member 21A	0.010
PAK7	p21 protein (Cdc42/Rac)-activated kinase 7	0.010
OTP	orthopedia homeobox	0.010
EGR2	early growth response 2	0.010
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.010
RNPS1	RNA binding protein S1, serine-rich domain	0.010
RGS2	regulator of G-protein signaling 2, 24kDa	0.010
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.010
ITK	IL2-inducible T-cell kinase	0.010
LGALS9	lectin, galactoside-binding, soluble, 9	0.010
BCAR1	breast cancer anti-estrogen resistance 1	0.010
POU4F1	POU class 4 homeobox 1	0.010	Human
KIAA1683	KIAA1683	0.010
PRC1	protein regulator of cytokinesis 1	0.010	Fly
HOXD12	homeobox D12	0.010
SCARF1	scavenger receptor class F, member 1	0.010
STAT5A	signal transducer and activator of transcription 5A	0.010
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.010
KRT1	keratin 1	0.010
UBD	ubiquitin D	0.010