IMP: Integrative Multi-species Prediction

Homo sapiens

18 genes annotated in human

mrna stabilization

Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mrna stabilization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "mrna stabilization" (in gray)

Name	Description	Probability	Func Analog Organism
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	1.000	Rat
MAPK14	mitogen-activated protein kinase 14	0.982
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.970
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.928
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.913
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.874
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.826	Mouse
TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	0.805
IRAK1	interleukin-1 receptor-associated kinase 1	0.784
PRMT1	protein arginine methyltransferase 1	0.739
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.661	Human
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.603
YBX1	Y box binding protein 1	0.485
MAPK1	mitogen-activated protein kinase 1	0.444
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.395
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.359
RB1	retinoblastoma 1	0.323
RBMX	RNA binding motif protein, X-linked	0.321
TOP1	topoisomerase (DNA) I	0.306
PTBP1	polypyrimidine tract binding protein 1	0.278
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.265
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.205
ILF3	interleukin enhancer binding factor 3, 90kDa	0.178
RBL2	retinoblastoma-like 2 (p130)	0.157
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.156
DUSP1	dual specificity phosphatase 1	0.155
MAPK6	mitogen-activated protein kinase 6	0.138
PABPC1	poly(A) binding protein, cytoplasmic 1	0.122
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.112
E2F2	E2F transcription factor 2	0.104	Human
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.102
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.101
HMGA2	high mobility group AT-hook 2	0.101
RBL1	retinoblastoma-like 1 (p107)	0.098
IRAK2	interleukin-1 receptor-associated kinase 2	0.097
HSF1	heat shock transcription factor 1	0.096
TFDP1	transcription factor Dp-1	0.087
CUX1	cut-like homeobox 1	0.085
E2F4	E2F transcription factor 4, p107/p130-binding	0.078	Human
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.075
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.075
QKI	quaking homolog, KH domain RNA binding (mouse)	0.068	Zebrafish
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.067
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.066
TLR4	toll-like receptor 4	0.063
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.061
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.058
RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))	0.058	Human
E2F1	E2F transcription factor 1	0.058
SFPQ	splicing factor proline/glutamine-rich	0.056
PURA	purine-rich element binding protein A	0.055
DAZL	deleted in azoospermia-like	0.055
FUS	fused in sarcoma	0.050
E2F3	E2F transcription factor 3	0.050	Human
NONO	non-POU domain containing, octamer-binding	0.047
MYD88	myeloid differentiation primary response gene (88)	0.046
SRSF1	serine/arginine-rich splicing factor 1	0.043
PHC2	polyhomeotic homolog 2 (Drosophila)	0.042
SF1	splicing factor 1	0.041
IRAK4	interleukin-1 receptor-associated kinase 4	0.041
PGF	placental growth factor	0.035
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.034
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.031
PUM2	pumilio homolog 2 (Drosophila)	0.030
SRSF9	serine/arginine-rich splicing factor 9	0.030
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.029
PTBP2	polypyrimidine tract binding protein 2	0.029
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.027
PCBP1	poly(rC) binding protein 1	0.027
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.027
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.025
CELF1	CUGBP, Elav-like family member 1	0.025
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.025
BTG2	BTG family, member 2	0.024
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.024
TRA2B	transformer 2 beta homolog (Drosophila)	0.024
AHR	aryl hydrocarbon receptor	0.023
SNIP1	Smad nuclear interacting protein 1	0.022
LIN9	lin-9 homolog (C. elegans)	0.021
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.021
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.021
CUL3	cullin 3	0.020
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.019
GSK3A	glycogen synthase kinase 3 alpha	0.019
AEBP2	AE binding protein 2	0.019
MAX	MYC associated factor X	0.018
MAP2K3	mitogen-activated protein kinase kinase 3	0.018
HDAC11	histone deacetylase 11	0.018
SAMHD1	SAM domain and HD domain 1	0.018
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.017
IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	0.017	Human
LIN54	lin-54 homolog (C. elegans)	0.017
FBXO33	F-box protein 33	0.017
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.016
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.016	Human
CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.016
LIMK1	LIM domain kinase 1	0.016
RBM4	RNA binding motif protein 4	0.015
BOLL	bol, boule-like (Drosophila)	0.015
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.015
MAPK11	mitogen-activated protein kinase 11	0.014
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.014	Human
SRSF5	serine/arginine-rich splicing factor 5	0.014
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.014
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.014
HMGA1	high mobility group AT-hook 1	0.013
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.013
EWSR1	Ewing sarcoma breakpoint region 1	0.013
AXIN1	axin 1	0.013	Human
MAPK3	mitogen-activated protein kinase 3	0.013
WDR83	WD repeat domain 83	0.013
HABP4	hyaluronan binding protein 4	0.012
BHLHE40	basic helix-loop-helix family, member e40	0.012
TP63	tumor protein p63	0.012
FOSL2	FOS-like antigen 2	0.012
MAST1	microtubule associated serine/threonine kinase 1	0.012
PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	0.012
DUSP7	dual specificity phosphatase 7	0.012
CDK6	cyclin-dependent kinase 6	0.011
CNBP	CCHC-type zinc finger, nucleic acid binding protein	0.011
CBX6	chromobox homolog 6	0.011
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.011
LMO3	LIM domain only 3 (rhombotin-like 2)	0.011
FRK	fyn-related kinase	0.011
NCOA6	nuclear receptor coactivator 6	0.010