IMP: Integrative Multi-species Prediction

Homo sapiens

40 genes annotated in human

negative regulation of immune response

Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of immune response"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of immune response" (in gray)

Name	Description	Probability	Func Analog Organism
C1S	complement component 1, s subcomponent	0.884	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.879
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.854	Human
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.827
CD86	CD86 molecule	0.827
HLA-A	major histocompatibility complex, class I, A	0.821
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.813	Human
HLA-C	major histocompatibility complex, class I, C	0.799	Human
HLA-G	major histocompatibility complex, class I, G	0.789	Human
IL4R	interleukin 4 receptor	0.786	Mouse
GHR	growth hormone receptor	0.726
B2M	beta-2-microglobulin	0.725
ALB	albumin	0.680
HLA-E	major histocompatibility complex, class I, E	0.677
CD80	CD80 molecule	0.664
CCL4	chemokine (C-C motif) ligand 4	0.649	Human
CD14	CD14 molecule	0.645
SMAD4	SMAD family member 4	0.641
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.613	Mouse
CCR1	chemokine (C-C motif) receptor 1	0.591	Mouse
C1R	complement component 1, r subcomponent	0.578	Human
CCR5	chemokine (C-C motif) receptor 5	0.562
NCOR2	nuclear receptor corepressor 2	0.522
COL1A2	collagen, type I, alpha 2	0.504	Human
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.500	Mouse
CXCL9	chemokine (C-X-C motif) ligand 9	0.491
IL2RG	interleukin 2 receptor, gamma	0.489
COL1A1	collagen, type I, alpha 1	0.487	Human
IL2RB	interleukin 2 receptor, beta	0.453
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.449
HLA-B	major histocompatibility complex, class I, B	0.440
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.425
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.411
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.399	Human
COL3A1	collagen, type III, alpha 1	0.384
THOC4	THO complex 4	0.376
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.303
TFF1	trefoil factor 1	0.283
PILRA	paired immunoglobin-like type 2 receptor alpha	0.279
CFH	complement factor H	0.276
SOCS3	suppressor of cytokine signaling 3	0.271
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.270	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.266
THOC5	THO complex 5	0.260
CCR7	chemokine (C-C motif) receptor 7	0.247
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.237
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.236
TAPBP	TAP binding protein (tapasin)	0.233
PML	promyelocytic leukemia	0.232
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.232
CCL22	chemokine (C-C motif) ligand 22	0.231	Human
C2	complement component 2	0.228
SIGLEC7	sialic acid binding Ig-like lectin 7	0.225
JAK2	Janus kinase 2	0.224
HLA-F	major histocompatibility complex, class I, F	0.220	Human
MED15	mediator complex subunit 15	0.217
TRAF1	TNF receptor-associated factor 1	0.209
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.205
ARRB1	arrestin, beta 1	0.204	Human
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.204
CCL8	chemokine (C-C motif) ligand 8	0.193	Human
HP	haptoglobin	0.186
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.185
IL10RA	interleukin 10 receptor, alpha	0.179
SP100	SP100 nuclear antigen	0.178
CCL5	chemokine (C-C motif) ligand 5	0.176	Human
IFNG	interferon, gamma	0.173
ATF2	activating transcription factor 2	0.164
MED10	mediator complex subunit 10	0.164
CXCL10	chemokine (C-X-C motif) ligand 10	0.162
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.161	Mouse Fly
SLAMF1	signaling lymphocytic activation molecule family member 1	0.160
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.159
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.159
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.154
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.151
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.151
APOC1	apolipoprotein C-I	0.144
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.143
IL10	interleukin 10	0.142
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.141
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.140
ENG	endoglin	0.138
HLA-DMB	major histocompatibility complex, class II, DM beta	0.136
HK3	hexokinase 3 (white cell)	0.125
CCL2	chemokine (C-C motif) ligand 2	0.125	Human
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.123
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.123
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.123
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.123
TGFB1	transforming growth factor, beta 1	0.120
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.119	Mouse
TGFB3	transforming growth factor, beta 3	0.117
DDR2	discoidin domain receptor tyrosine kinase 2	0.116
IL22RA1	interleukin 22 receptor, alpha 1	0.113
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.113
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.112
BTN3A3	butyrophilin, subfamily 3, member A3	0.111
CCL19	chemokine (C-C motif) ligand 19	0.110	Human
COL5A2	collagen, type V, alpha 2	0.109	Human
CCL7	chemokine (C-C motif) ligand 7	0.105	Human
CD163	CD163 molecule	0.105
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.104
ZC3H12A	zinc finger CCCH-type containing 12A	0.100
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.099
IRAK2	interleukin-1 receptor-associated kinase 2	0.098
IRF9	interferon regulatory factor 9	0.096
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.096	Human
IDE	insulin-degrading enzyme	0.096
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.096
APOA1	apolipoprotein A-I	0.091
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.088
C1QA	complement component 1, q subcomponent, A chain	0.088
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.085	Human
CCL13	chemokine (C-C motif) ligand 13	0.085	Human
TRIM39	tripartite motif containing 39	0.084	Human
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.082
TRIM5	tripartite motif containing 5	0.081	Human
TEK	TEK tyrosine kinase, endothelial	0.081
TNF	tumor necrosis factor	0.080
INSR	insulin receptor	0.080
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.079
TRIM25	tripartite motif containing 25	0.076
ICAM1	intercellular adhesion molecule 1	0.075
CUL2	cullin 2	0.075
IGSF6	immunoglobulin superfamily, member 6	0.075
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.074
BCL6	B-cell CLL/lymphoma 6	0.072	Mouse
IL1B	interleukin 1, beta	0.071
IRF2	interferon regulatory factor 2	0.070
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.069
COL4A1	collagen, type IV, alpha 1	0.067
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.066
HCP5	HLA complex P5	0.065
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.064
IL22RA2	interleukin 22 receptor, alpha 2	0.064
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.064
HIPK2	homeodomain interacting protein kinase 2	0.063
RALBP1	ralA binding protein 1	0.063
RARA	retinoic acid receptor, alpha	0.063
APOE	apolipoprotein E	0.062	Human
PTAFR	platelet-activating factor receptor	0.062
CYBB	cytochrome b-245, beta polypeptide	0.060
BTN3A1	butyrophilin, subfamily 3, member A1	0.060
VSIG4	V-set and immunoglobulin domain containing 4	0.058
IRF8	interferon regulatory factor 8	0.057
SLAMF8	SLAM family member 8	0.057
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.057
LCAT	lecithin-cholesterol acyltransferase	0.056
IL4	interleukin 4	0.056	Mouse
TRIM22	tripartite motif containing 22	0.056	Human
LOX	lysyl oxidase	0.055
GRB7	growth factor receptor-bound protein 7	0.054
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.054
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.054
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.054
HCK	hemopoietic cell kinase	0.053
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.053
CXCL13	chemokine (C-X-C motif) ligand 13	0.052
CXCL11	chemokine (C-X-C motif) ligand 11	0.052
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.051
DCN	decorin	0.050
C19orf50	chromosome 19 open reading frame 50	0.050
DERL1	Der1-like domain family, member 1	0.050
HNF4A	hepatocyte nuclear factor 4, alpha	0.049
FPR3	formyl peptide receptor 3	0.049
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.049
BIRC3	baculoviral IAP repeat containing 3	0.048
SMAD1	SMAD family member 1	0.047
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.046
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.046
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.046
CCR4	chemokine (C-C motif) receptor 4	0.045
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.045
RXRA	retinoid X receptor, alpha	0.045
CTSS	cathepsin S	0.045
IGF2R	insulin-like growth factor 2 receptor	0.045
ADAMDEC1	ADAM-like, decysin 1	0.044
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.044
IL2RA	interleukin 2 receptor, alpha	0.044
CMKLR1	chemokine-like receptor 1	0.044
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.044
MED30	mediator complex subunit 30	0.044
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.043
C5AR1	complement component 5a receptor 1	0.043
UBD	ubiquitin D	0.043
PLEK	pleckstrin	0.042
SMAD2	SMAD family member 2	0.042
NLRP3	NLR family, pyrin domain containing 3	0.042	Human
FAS	Fas (TNF receptor superfamily, member 6)	0.042
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.042
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.041
COL6A1	collagen, type VI, alpha 1	0.041
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.041
IDO1	indoleamine 2,3-dioxygenase 1	0.041
TGFBR1	transforming growth factor, beta receptor 1	0.040
ALOX5	arachidonate 5-lipoxygenase	0.040
MICA	MHC class I polypeptide-related sequence A	0.040
COL5A1	collagen, type V, alpha 1	0.040	Human
CFI	complement factor I	0.039
IL18RAP	interleukin 18 receptor accessory protein	0.039
CD22	CD22 molecule	0.039
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.038	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.038
CCL11	chemokine (C-C motif) ligand 11	0.038	Human
SYK	spleen tyrosine kinase	0.038
ATF3	activating transcription factor 3	0.038
ARIH2	ariadne homolog 2 (Drosophila)	0.038
TNRC6B	trinucleotide repeat containing 6B	0.037
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.037
NRP1	neuropilin 1	0.037
IGFBP3	insulin-like growth factor binding protein 3	0.036
IL13	interleukin 13	0.036
ZNF473	zinc finger protein 473	0.036
CD69	CD69 molecule	0.036
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.036
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.035	Human
HDAC9	histone deacetylase 9	0.035
SLA	Src-like-adaptor	0.035
CH25H	cholesterol 25-hydroxylase	0.034
SOCS2	suppressor of cytokine signaling 2	0.034
ATF7IP	activating transcription factor 7 interacting protein	0.034
SIRPB1	signal-regulatory protein beta 1	0.034
CD40	CD40 molecule, TNF receptor superfamily member 5	0.033
TRIM21	tripartite motif containing 21	0.033	Human
NCOA3	nuclear receptor coactivator 3	0.033
AQP9	aquaporin 9	0.033
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.033
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.033
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.033
MED28	mediator complex subunit 28	0.031
C3AR1	complement component 3a receptor 1	0.031
FGL2	fibrinogen-like 2	0.031
THOC2	THO complex 2	0.031
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.031
NLRC5	NLR family, CARD domain containing 5	0.031
CD33	CD33 molecule	0.031
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.030
ATMIN	ATM interactor	0.030
TPP1	tripeptidyl peptidase I	0.030
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.030
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.030
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.030
SLC15A3	solute carrier family 15, member 3	0.030
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.029
CCL3	chemokine (C-C motif) ligand 3	0.029	Human
BTN3A2	butyrophilin, subfamily 3, member A2	0.029
CXCL2	chemokine (C-X-C motif) ligand 2	0.029
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.029
ZNF830	zinc finger protein 830	0.029
NEK6	NIMA (never in mitosis gene a)-related kinase 6	0.029
TRIM33	tripartite motif containing 33	0.029
TRIM26	tripartite motif containing 26	0.028
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.028
ADAM12	ADAM metallopeptidase domain 12	0.028
STAT5A	signal transducer and activator of transcription 5A	0.028	Fly
CSF1	colony stimulating factor 1 (macrophage)	0.028
CD40LG	CD40 ligand	0.027
RNF11	ring finger protein 11	0.027
APOC2	apolipoprotein C-II	0.027
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.027
TF	transferrin	0.027
POSTN	periostin, osteoblast specific factor	0.027
TRIM17	tripartite motif containing 17	0.027	Human
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.027
STAT2	signal transducer and activator of transcription 2, 113kDa	0.027
CD300A	CD300a molecule	0.026
ZNF263	zinc finger protein 263	0.026
OAZ1	ornithine decarboxylase antizyme 1	0.026
TRIM43	tripartite motif containing 43	0.026
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.026
PPARA	peroxisome proliferator-activated receptor alpha	0.026	Human
FPR2	formyl peptide receptor 2	0.026
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.026
APOC3	apolipoprotein C-III	0.026
WISP1	WNT1 inducible signaling pathway protein 1	0.026
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.026
IL7R	interleukin 7 receptor	0.026	Mouse
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.025
TREM1	triggering receptor expressed on myeloid cells 1	0.025
IL21R	interleukin 21 receptor	0.025
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.025
IRF4	interferon regulatory factor 4	0.025
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.025
CPNE6	copine VI (neuronal)	0.025
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.024
AOAH	acyloxyacyl hydrolase (neutrophil)	0.024
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.024
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	0.024
CD48	CD48 molecule	0.024
APOL3	apolipoprotein L, 3	0.024
CLEC10A	C-type lectin domain family 10, member A	0.024
CYTIP	cytohesin 1 interacting protein	0.024
KRT81	keratin 81	0.024
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.024
NOD2	nucleotide-binding oligomerization domain containing 2	0.024	Human
IFI44	interferon-induced protein 44	0.023
DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.023
APOB	apolipoprotein B (including Ag(x) antigen)	0.023
CD209	CD209 molecule	0.023
MED1	mediator complex subunit 1	0.023
CLU	clusterin	0.023
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.023	Human
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.023	Rat
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.023
EBI3	Epstein-Barr virus induced 3	0.023
XAF1	XIAP associated factor 1	0.023
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.022
SIGLEC9	sialic acid binding Ig-like lectin 9	0.022
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.022	Mouse
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.022
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.022
A2M	alpha-2-macroglobulin	0.022
SMN1	survival of motor neuron 1, telomeric	0.022
CFB	complement factor B	0.022
VCAM1	vascular cell adhesion molecule 1	0.022
LGALS9	lectin, galactoside-binding, soluble, 9	0.022
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.022
PPAP2B	phosphatidic acid phosphatase type 2B	0.021	Fly
ITGB1BP1	integrin beta 1 binding protein 1	0.021
CDK8	cyclin-dependent kinase 8	0.021
SAA4	serum amyloid A4, constitutive	0.021
IL32	interleukin 32	0.021
TRADD	TNFRSF1A-associated via death domain	0.021
SH2D1B	SH2 domain containing 1B	0.021	Mouse
KDM6A	lysine (K)-specific demethylase 6A	0.021
LGALS1	lectin, galactoside-binding, soluble, 1	0.021
C8B	complement component 8, beta polypeptide	0.021
CD84	CD84 molecule	0.021
MXRA5	matrix-remodelling associated 5	0.021
PGR	progesterone receptor	0.021
CPN1	carboxypeptidase N, polypeptide 1	0.021
FCAR	Fc fragment of IgA, receptor for	0.021	Human
COL6A3	collagen, type VI, alpha 3	0.020
MRPL49	mitochondrial ribosomal protein L49	0.020
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.020
APCS	amyloid P component, serum	0.020
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.020
NNMT	nicotinamide N-methyltransferase	0.020
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.020
RIPK2	receptor-interacting serine-threonine kinase 2	0.020
APP	amyloid beta (A4) precursor protein	0.020
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.020
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.020
BATF	basic leucine zipper transcription factor, ATF-like	0.020
S100A12	S100 calcium binding protein A12	0.020
CCL20	chemokine (C-C motif) ligand 20	0.020	Human
IFI44L	interferon-induced protein 44-like	0.020
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.019
MASP2	mannan-binding lectin serine peptidase 2	0.019	Human
OLFML3	olfactomedin-like 3	0.019
UBASH3B	ubiquitin associated and SH3 domain containing B	0.019
FBN1	fibrillin 1	0.019
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.019
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.019
CD274	CD274 molecule	0.019
SFRP4	secreted frizzled-related protein 4	0.019
SH2D2A	SH2 domain containing 2A	0.019
IL19	interleukin 19	0.019	Human
TLR8	toll-like receptor 8	0.019
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.019
CD300C	CD300c molecule	0.019	Human
TTR	transthyretin	0.019
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.019
WIPF1	WAS/WASL interacting protein family, member 1	0.019
IFITM1	interferon induced transmembrane protein 1 (9-27)	0.019
IL17RA	interleukin 17 receptor A	0.019
MAPK14	mitogen-activated protein kinase 14	0.019	Fly
CCR3	chemokine (C-C motif) receptor 3	0.018
NLRC4	NLR family, CARD domain containing 4	0.018
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.018
JAK1	Janus kinase 1	0.018
CYTH4	cytohesin 4	0.018
CLEC7A	C-type lectin domain family 7, member A	0.018
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.018
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.018
TRIM8	tripartite motif containing 8	0.018
APOA2	apolipoprotein A-II	0.018
C8A	complement component 8, alpha polypeptide	0.018
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.018	Human
CAPN1	calpain 1, (mu/I) large subunit	0.018
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.018
TRIM34	tripartite motif containing 34	0.018
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.018
ZMYND11	zinc finger, MYND-type containing 11	0.018
DUSP9	dual specificity phosphatase 9	0.018
ASGR2	asialoglycoprotein receptor 2	0.018
SDS	serine dehydratase	0.018
MED8	mediator complex subunit 8	0.018
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.018
CXCR6	chemokine (C-X-C motif) receptor 6	0.017
STAT4	signal transducer and activator of transcription 4	0.017
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.017
EPOR	erythropoietin receptor	0.017
ELK1	ELK1, member of ETS oncogene family	0.017
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.017
NCOR1	nuclear receptor corepressor 1	0.017
CTSK	cathepsin K	0.017
PECAM1	platelet/endothelial cell adhesion molecule	0.017
RGS1	regulator of G-protein signaling 1	0.017
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.017
RBM8A	RNA binding motif protein 8A	0.017
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.017
SLAMF7	SLAM family member 7	0.017
LAMP3	lysosomal-associated membrane protein 3	0.017
CHD9	chromodomain helicase DNA binding protein 9	0.017
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.017
ITGA1	integrin, alpha 1	0.017
AHR	aryl hydrocarbon receptor	0.017
FNDC1	fibronectin type III domain containing 1	0.017
CCL23	chemokine (C-C motif) ligand 23	0.016	Human
TRAF3IP3	TRAF3 interacting protein 3	0.016
IL18BP	interleukin 18 binding protein	0.016
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.016
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.016
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.016
NRP2	neuropilin 2	0.016
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.016
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.016
JAK3	Janus kinase 3	0.016	Mouse
PCDH9	protocadherin 9	0.016
SP110	SP110 nuclear body protein	0.016
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.016
IL1RN	interleukin 1 receptor antagonist	0.016
C19orf66	chromosome 19 open reading frame 66	0.016
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.016
HDAC5	histone deacetylase 5	0.016
STAT5B	signal transducer and activator of transcription 5B	0.016	Fly
NUP214	nucleoporin 214kDa	0.016
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.016
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.016
CD37	CD37 molecule	0.016
COMMD1	copper metabolism (Murr1) domain containing 1	0.016
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.016
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.016
MARCO	macrophage receptor with collagenous structure	0.015
MYO1F	myosin IF	0.015
PXDN	peroxidasin homolog (Drosophila)	0.015
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.015
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.015
TMEM173	transmembrane protein 173	0.015
HELZ	helicase with zinc finger	0.015
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.015
CD72	CD72 molecule	0.015
MKRN3	makorin ring finger protein 3	0.015
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.015
TP53BP1	tumor protein p53 binding protein 1	0.015
RPL11	ribosomal protein L11	0.015
CP	ceruloplasmin (ferroxidase)	0.015
IL8	interleukin 8	0.015
RGL1	ral guanine nucleotide dissociation stimulator-like 1	0.015
KNG1	kininogen 1	0.015
THY1	Thy-1 cell surface antigen	0.015
INHBA	inhibin, beta A	0.015
MAVS	mitochondrial antiviral signaling protein	0.015
HLA-DQB2	major histocompatibility complex, class II, DQ beta 2	0.015
FGA	fibrinogen alpha chain	0.015
HAMP	hepcidin antimicrobial peptide	0.015
CD164	CD164 molecule, sialomucin	0.015
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.014
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.014
SELE	selectin E	0.014
MAT1A	methionine adenosyltransferase I, alpha	0.014
MBL2	mannose-binding lectin (protein C) 2, soluble	0.014
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.014
TFEC	transcription factor EC	0.014
PLTP	phospholipid transfer protein	0.014
OLFML2B	olfactomedin-like 2B	0.014
SOD2	superoxide dismutase 2, mitochondrial	0.014
CLIC2	chloride intracellular channel 2	0.014
BGN	biglycan	0.014
ANGPT2	angiopoietin 2	0.014
RFWD2	ring finger and WD repeat domain 2	0.014
SMAD3	SMAD family member 3	0.014
ICOS	inducible T-cell co-stimulator	0.014
IL7	interleukin 7	0.014
GPR65	G protein-coupled receptor 65	0.014
OSMR	oncostatin M receptor	0.014
IL13RA1	interleukin 13 receptor, alpha 1	0.014
FOSL1	FOS-like antigen 1	0.014
IFNB1	interferon, beta 1, fibroblast	0.014
CHCHD2	coiled-coil-helix-coiled-coil-helix domain containing 2	0.014
ARRB2	arrestin, beta 2	0.014
ZNF593	zinc finger protein 593	0.014
CCL1	chemokine (C-C motif) ligand 1	0.014	Human
HR	hairless homolog (mouse)	0.014
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.014
RAD50	RAD50 homolog (S. cerevisiae)	0.014
COL11A1	collagen, type XI, alpha 1	0.014	Human
BATF2	basic leucine zipper transcription factor, ATF-like 2	0.014
LAPTM5	lysosomal protein transmembrane 5	0.014
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.014
TRIM52	tripartite motif containing 52	0.014
PRKCA	protein kinase C, alpha	0.013
DAXX	death-domain associated protein	0.013
GSN	gelsolin	0.013
PKLR	pyruvate kinase, liver and RBC	0.013
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.013
CD1D	CD1d molecule	0.013
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.013
CHIT1	chitinase 1 (chitotriosidase)	0.013
SELL	selectin L	0.013
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.013
C4BPB	complement component 4 binding protein, beta	0.013
PHF11	PHD finger protein 11	0.013
CD4	CD4 molecule	0.013
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.013
PGCP	plasma glutamate carboxypeptidase	0.013
TMEM140	transmembrane protein 140	0.013
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.013
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.013
IL24	interleukin 24	0.013	Human
EVI2A	ecotropic viral integration site 2A	0.013
LYZ	lysozyme	0.013	Fly
IFNGR1	interferon gamma receptor 1	0.013
ANG	angiogenin, ribonuclease, RNase A family, 5	0.013
LECT2	leukocyte cell-derived chemotaxin 2	0.013
GBP2	guanylate binding protein 2, interferon-inducible	0.013
TRIM41	tripartite motif containing 41	0.013	Human
TRIM31	tripartite motif containing 31	0.013	Human
FSTL1	follistatin-like 1	0.013
STK10	serine/threonine kinase 10	0.013
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.013
RNASE6	ribonuclease, RNase A family, k6	0.013
POMP	proteasome maturation protein	0.013
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.013
CD83	CD83 molecule	0.013
GBP5	guanylate binding protein 5	0.013
CD1C	CD1c molecule	0.013
CLEC5A	C-type lectin domain family 5, member A	0.013
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.012
AMBP	alpha-1-microglobulin/bikunin precursor	0.012
CYLD	cylindromatosis (turban tumor syndrome)	0.012
GPR84	G protein-coupled receptor 84	0.012
LBP	lipopolysaccharide binding protein	0.012
BLNK	B-cell linker	0.012
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.012	Human
CCBP2	chemokine binding protein 2	0.012
TARBP2	TAR (HIV-1) RNA binding protein 2	0.012
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.012
BTK	Bruton agammaglobulinemia tyrosine kinase	0.012
COL10A1	collagen, type X, alpha 1	0.012
GNAS	GNAS complex locus	0.012
MSR1	macrophage scavenger receptor 1	0.012
IGFBP5	insulin-like growth factor binding protein 5	0.012
TRAF2	TNF receptor-associated factor 2	0.012
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.012
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.012
HDAC10	histone deacetylase 10	0.012
TGFBR3	transforming growth factor, beta receptor III	0.012
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.012
CD1B	CD1b molecule	0.012
CCR2	chemokine (C-C motif) receptor 2	0.012	Mouse
GLT8D2	glycosyltransferase 8 domain containing 2	0.012
ACVR1	activin A receptor, type I	0.012	Fly
TUBGCP4	tubulin, gamma complex associated protein 4	0.012
VNN2	vanin 2	0.012
MAPK15	mitogen-activated protein kinase 15	0.012
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.012
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.012
GPNMB	glycoprotein (transmembrane) nmb	0.012
DUSP7	dual specificity phosphatase 7	0.012
S100A5	S100 calcium binding protein A5	0.012
TNFRSF8	tumor necrosis factor receptor superfamily, member 8	0.012
IL1F5	interleukin 1 family, member 5 (delta)	0.012
RNF113A	ring finger protein 113A	0.011
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.011
DPT	dermatopontin	0.011
IL9	interleukin 9	0.011
BIRC2	baculoviral IAP repeat containing 2	0.011
CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	0.011
S100A6	S100 calcium binding protein A6	0.011
IL18R1	interleukin 18 receptor 1	0.011
TRIM4	tripartite motif containing 4	0.011	Human
CXCR2	chemokine (C-X-C motif) receptor 2	0.011
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.011	Mouse
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.011
INSL4	insulin-like 4 (placenta)	0.011
CTSO	cathepsin O	0.011
COL14A1	collagen, type XIV, alpha 1	0.011
DCLRE1C	DNA cross-link repair 1C	0.011
BIN2	bridging integrator 2	0.011
ADAP2	ArfGAP with dual PH domains 2	0.011
ASCC2	activating signal cointegrator 1 complex subunit 2	0.011
UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1	0.011
C1QB	complement component 1, q subcomponent, B chain	0.011
MAPK10	mitogen-activated protein kinase 10	0.011
PDCD1LG2	programmed cell death 1 ligand 2	0.011
IL1A	interleukin 1, alpha	0.011
SAA1	serum amyloid A1	0.011
UROD	uroporphyrinogen decarboxylase	0.011
NXF3	nuclear RNA export factor 3	0.011
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.011
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.011
GGT5	gamma-glutamyltransferase 5	0.011
C1orf38	chromosome 1 open reading frame 38	0.011
ZNRD1	zinc ribbon domain containing 1	0.011
EVI2B	ecotropic viral integration site 2B	0.011
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.011
TRIM27	tripartite motif containing 27	0.011
GPR35	G protein-coupled receptor 35	0.011
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.011
HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2	0.011
LST1	leukocyte specific transcript 1	0.011
C1QC	complement component 1, q subcomponent, C chain	0.011
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.011
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.011
PHIP	pleckstrin homology domain interacting protein	0.011
SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	0.011	Mouse
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.011
CCR9	chemokine (C-C motif) receptor 9	0.011
FMO1	flavin containing monooxygenase 1	0.011
PLA1A	phospholipase A1 member A	0.011
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.011
DEFB4A	defensin, beta 4A	0.010
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.010
NFYC	nuclear transcription factor Y, gamma	0.010
LRP10	low density lipoprotein receptor-related protein 10	0.010
CXCL5	chemokine (C-X-C motif) ligand 5	0.010
AFM	afamin	0.010
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.010
APOBR	apolipoprotein B receptor	0.010
ITK	IL2-inducible T-cell kinase	0.010
RNASE3	ribonuclease, RNase A family, 3	0.010
SLC22A14	solute carrier family 22, member 14	0.010
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.010
TYK2	tyrosine kinase 2	0.010
SCARF1	scavenger receptor class F, member 1	0.010
SAA2	serum amyloid A2	0.010
MED29	mediator complex subunit 29	0.010
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.010
LOXL4	lysyl oxidase-like 4	0.010
RGS12	regulator of G-protein signaling 12	0.010
SASH3	SAM and SH3 domain containing 3	0.010
IL3RA	interleukin 3 receptor, alpha (low affinity)	0.010
PIGR	polymeric immunoglobulin receptor	0.010	Human
DAB2IP	DAB2 interacting protein	0.010
CCL17	chemokine (C-C motif) ligand 17	0.010	Human
CAV1	caveolin 1, caveolae protein, 22kDa	0.010
CSF3	colony stimulating factor 3 (granulocyte)	0.010
NUAK1	NUAK family, SNF1-like kinase, 1	0.010
HDAC7	histone deacetylase 7	0.010