IMP: Integrative Multi-species Prediction

Homo sapiens

19 genes annotated in human

Multi-species View

regulation of epidermis development

GO:0045682

Any process that modulates the frequency, rate or extent of epidermis development.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of epidermis development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of epidermis development" (in gray)

Name	Description	Probability	Func Analog Organism
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.872
BMPR1A	bone morphogenetic protein receptor, type IA	0.622
AR	androgen receptor	0.591
CREBBP	CREB binding protein	0.581
HOXB5	homeobox B5	0.551	Human
NCOR2	nuclear receptor corepressor 2	0.499
ESR1	estrogen receptor 1	0.468
SFN	stratifin	0.452	Mouse
JAG1	jagged 1	0.444
NCOA1	nuclear receptor coactivator 1	0.440	Human
HOXA5	homeobox A5	0.401	Human
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.400
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.387
NCOR1	nuclear receptor corepressor 1	0.348
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.320
BBS10	Bardet-Biedl syndrome 10	0.319
HOXA10	homeobox A10	0.307
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.302
NOTCH3	notch 3	0.258
FSTL1	follistatin-like 1	0.254	Human
HOXA7	homeobox A7	0.227
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.210
PKP3	plakophilin 3	0.185
CTNND1	catenin (cadherin-associated protein), delta 1	0.182
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.137
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.128	Human
HOXB3	homeobox B3	0.125
HOXA11	homeobox A11	0.124
NCOA2	nuclear receptor coactivator 2	0.124	Human
ZNF746	zinc finger protein 746	0.120
JUP	junction plakoglobin	0.109
HOXB9	homeobox B9	0.108
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.103
RXRA	retinoid X receptor, alpha	0.100
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.087
HOXB6	homeobox B6	0.087	Human
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.086
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.085
KRT5	keratin 5	0.084
HOXA4	homeobox A4	0.084	Human
HIPK2	homeodomain interacting protein kinase 2	0.083
MSX1	msh homeobox 1	0.076
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.074
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.074
TGFB1	transforming growth factor, beta 1	0.068	Human
EPPK1	epiplakin 1	0.067
HOXC6	homeobox C6	0.065	Human
TRAF1	TNF receptor-associated factor 1	0.065
HOXC10	homeobox C10	0.063
NCOA3	nuclear receptor coactivator 3	0.063
HOXB7	homeobox B7	0.062	Human
NME1	non-metastatic cells 1, protein (NM23A) expressed in	0.060
NOTCH1	notch 1	0.057	Mouse
RND3	Rho family GTPase 3	0.057
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.056
HOXA2	homeobox A2	0.055
ZNF775	zinc finger protein 775	0.053
JUB	jub, ajuba homolog (Xenopus laevis)	0.051
WNT3A	wingless-type MMTV integration site family, member 3A	0.050
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.050
LAD1	ladinin 1	0.049
RUNX1	runt-related transcription factor 1	0.049
NME3	non-metastatic cells 3, protein expressed in	0.048	Human
HR	hairless homolog (mouse)	0.046
PSEN1	presenilin 1	0.045
WNT5A	wingless-type MMTV integration site family, member 5A	0.044
ZFYVE9	zinc finger, FYVE domain containing 9	0.043
HOXA6	homeobox A6	0.043	Human
DDIT3	DNA-damage-inducible transcript 3	0.043
BHLHE40	basic helix-loop-helix family, member e40	0.041
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.041
STMN2	stathmin-like 2	0.038
TJP1	tight junction protein 1 (zona occludens 1)	0.038
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.038
NDP	Norrie disease (pseudoglioma)	0.037
ESR2	estrogen receptor 2 (ER beta)	0.035
FOXO1	forkhead box O1	0.035
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.034
NFIL3	nuclear factor, interleukin 3 regulated	0.034
INHBA	inhibin, beta A	0.033
EP300	E1A binding protein p300	0.033
ENG	endoglin	0.032
NCOA6	nuclear receptor coactivator 6	0.032
NME4	non-metastatic cells 4, protein expressed in	0.031
EHF	ets homologous factor	0.031
ELF5	E74-like factor 5 (ets domain transcription factor)	0.030
SFRP1	secreted frizzled-related protein 1	0.030
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.029
TNK2	tyrosine kinase, non-receptor, 2	0.029
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.029
KRT6C	keratin 6C	0.029
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.028
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.028
CREB1	cAMP responsive element binding protein 1	0.028
HTT	huntingtin	0.028
SKIL	SKI-like oncogene	0.027
CABLES1	Cdk5 and Abl enzyme substrate 1	0.027
SATB2	SATB homeobox 2	0.027
TNS4	tensin 4	0.027
RBM39	RNA binding motif protein 39	0.026
RARA	retinoic acid receptor, alpha	0.025
HNF4A	hepatocyte nuclear factor 4, alpha	0.025
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.025
GJA1	gap junction protein, alpha 1, 43kDa	0.025
SMAD2	SMAD family member 2	0.025
HOXA3	homeobox A3	0.024
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.024
MAML1	mastermind-like 1 (Drosophila)	0.024
KIAA1033	KIAA1033	0.024
HOXA1	homeobox A1	0.023
GSK3B	glycogen synthase kinase 3 beta	0.023
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.023
ATF3	activating transcription factor 3	0.022
UBQLN4	ubiquilin 4	0.022
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.022
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.022
TGFBR1	transforming growth factor, beta receptor 1	0.022
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.022
YY1	YY1 transcription factor	0.021
HOXB2	homeobox B2	0.021
PDE4DIP	phosphodiesterase 4D interacting protein	0.021
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.021
WDYHV1	WDYHV motif containing 1	0.020
BMP2	bone morphogenetic protein 2	0.020	Human
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.020
SP1	Sp1 transcription factor	0.020
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.019
PGR	progesterone receptor	0.019
CDK19	cyclin-dependent kinase 19	0.019
GLIS2	GLIS family zinc finger 2	0.019
AXIN1	axin 1	0.019
SART1	squamous cell carcinoma antigen recognized by T cells	0.019
NOTCH2	notch 2	0.019
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.019
CSNK1E	casein kinase 1, epsilon	0.018
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.018
MEST	mesoderm specific transcript homolog (mouse)	0.018
HOXB8	homeobox B8	0.018	Human
HOXB4	homeobox B4	0.017	Human
OCLN	occludin	0.017
SREK1	splicing regulatory glutamine/lysine-rich protein 1	0.017
PTK2	PTK2 protein tyrosine kinase 2	0.017
FOXC1	forkhead box C1	0.016
NXF1	nuclear RNA export factor 1	0.016
HOXC11	homeobox C11	0.016
DSP	desmoplakin	0.016
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.016
SALL2	sal-like 2 (Drosophila)	0.016
HMGA1	high mobility group AT-hook 1	0.015
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.015
SH2D3A	SH2 domain containing 3A	0.015
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.015
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.015
GRIP1	glutamate receptor interacting protein 1	0.015
FOXF2	forkhead box F2	0.015
PKP2	plakophilin 2	0.015
COL5A1	collagen, type V, alpha 1	0.015
HOXC4	homeobox C4	0.015	Human
FAM110A	family with sequence similarity 110, member A	0.015
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.014	Mouse
SRRM1	serine/arginine repetitive matrix 1	0.014
HOXC9	homeobox C9	0.014
ATXN1L	ataxin 1-like	0.014
TAL1	T-cell acute lymphocytic leukemia 1	0.014
TSG101	tumor susceptibility gene 101	0.014
HOXA13	homeobox A13	0.014
FOXO3	forkhead box O3	0.014
EGR1	early growth response 1	0.014
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.013
DLL1	delta-like 1 (Drosophila)	0.013	Mouse
FZD8	frizzled homolog 8 (Drosophila)	0.013	Human
TRIM29	tripartite motif containing 29	0.013
TFCP2L1	transcription factor CP2-like 1	0.013
APP	amyloid beta (A4) precursor protein	0.013
ZMYND8	zinc finger, MYND-type containing 8	0.013
BTRC	beta-transducin repeat containing	0.013
TCF4	transcription factor 4	0.013
ESRP1	epithelial splicing regulatory protein 1	0.013
TRAF2	TNF receptor-associated factor 2	0.013
TWIST1	twist homolog 1 (Drosophila)	0.013
FBLN1	fibulin 1	0.012
PTN	pleiotrophin	0.012
GRHL2	grainyhead-like 2 (Drosophila)	0.012
ARHGAP1	Rho GTPase activating protein 1	0.012
PNRC2	proline-rich nuclear receptor coactivator 2	0.012
TGFA	transforming growth factor, alpha	0.012
YAP1	Yes-associated protein 1	0.012
EPHA2	EPH receptor A2	0.012
PIM1	pim-1 oncogene	0.012
NOG	noggin	0.012
HOXD3	homeobox D3	0.012
PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.012
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.012
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.012
SRSF7	serine/arginine-rich splicing factor 7	0.012
S1PR5	sphingosine-1-phosphate receptor 5	0.012
KRT8	keratin 8	0.011
IQGAP1	IQ motif containing GTPase activating protein 1	0.011
COL4A6	collagen, type IV, alpha 6	0.011
MAT2A	methionine adenosyltransferase II, alpha	0.011
C1orf106	chromosome 1 open reading frame 106	0.011
CGN	cingulin	0.011
CHERP	calcium homeostasis endoplasmic reticulum protein	0.011
KAT2B	K(lysine) acetyltransferase 2B	0.011
PARVA	parvin, alpha	0.011
HOXD10	homeobox D10	0.011
HOXC13	homeobox C13	0.011
IGFBP6	insulin-like growth factor binding protein 6	0.011
CCND1	cyclin D1	0.011
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	0.011
SNW1	SNW domain containing 1	0.011
PHLDA2	pleckstrin homology-like domain, family A, member 2	0.011
ST5	suppression of tumorigenicity 5	0.011
MED13	mediator complex subunit 13	0.011
KANK2	KN motif and ankyrin repeat domains 2	0.011
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.011
MCC	mutated in colorectal cancers	0.010
ESRRG	estrogen-related receptor gamma	0.010
BMP7	bone morphogenetic protein 7	0.010
GPR87	G protein-coupled receptor 87	0.010
NGF	nerve growth factor (beta polypeptide)	0.010
GATA2	GATA binding protein 2	0.010
KRT18	keratin 18	0.010
SOX9	SRY (sex determining region Y)-box 9	0.010
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.010
DSG3	desmoglein 3	0.010
HOXC8	homeobox C8	0.010	Human
MED10	mediator complex subunit 10	0.010
S100A2	S100 calcium binding protein A2	0.010
SHROOM3	shroom family member 3	0.010
TGFB2	transforming growth factor, beta 2	0.010