IMP: Integrative Multi-species Prediction

Homo sapiens

19 genes annotated in human

muscle tissue morphogenesis

The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.

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In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "muscle tissue morphogenesis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "muscle tissue morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
TRIM63	tripartite motif containing 63	0.999
TNNC1	troponin C type 1 (slow)	0.991
TNNI1	troponin I type 1 (skeletal, slow)	0.982	Human Mouse
TPM1	tropomyosin 1 (alpha)	0.896
TCAP	titin-cap (telethonin)	0.862
MYOZ1	myozenin 1	0.732
MYOD1	myogenic differentiation 1	0.684
DSP	desmoplakin	0.678	Mouse
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.657
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.640
ACTA1	actin, alpha 1, skeletal muscle	0.590
SMYD1	SET and MYND domain containing 1	0.585
RARA	retinoic acid receptor, alpha	0.491
TNNT2	troponin T type 2 (cardiac)	0.473
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.462
TTN	titin	0.453
ESR2	estrogen receptor 2 (ER beta)	0.435
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.422
TPM2	tropomyosin 2 (beta)	0.401	Human
FSTL1	follistatin-like 1	0.363
CKM	creatine kinase, muscle	0.357
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.323
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.309
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.298	Human
TBX5	T-box 5	0.296
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.260	Human
NOTCH1	notch 1	0.253	Mouse
TNNI2	troponin I type 2 (skeletal, fast)	0.250	Human
JAG1	jagged 1	0.244
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.234
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.230
PSEN1	presenilin 1	0.224
GSK3B	glycogen synthase kinase 3 beta	0.221
SMAD3	SMAD family member 3	0.214
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.214	Human
EP300	E1A binding protein p300	0.203
INADL	InaD-like (Drosophila)	0.202
ESR1	estrogen receptor 1	0.191
TNNT3	troponin T type 3 (skeletal, fast)	0.188	Human
JUP	junction plakoglobin	0.174
ACVR1B	activin A receptor, type IB	0.166
MYH9	myosin, heavy chain 9, non-muscle	0.165
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.165
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.160	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.153
ACTN2	actinin, alpha 2	0.127
DES	desmin	0.123
CREBBP	CREB binding protein	0.118
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.114
PDLIM7	PDZ and LIM domain 7 (enigma)	0.110
MYBPC2	myosin binding protein C, fast type	0.107
TCF4	transcription factor 4	0.102
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.097
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.097	Human
TAL1	T-cell acute lymphocytic leukemia 1	0.091	Human
COL4A1	collagen, type IV, alpha 1	0.084
NEB	nebulin	0.080
TAGLN2	transgelin 2	0.080
MYOZ2	myozenin 2	0.073
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.072	Human
COL1A2	collagen, type I, alpha 2	0.072
NOTCH3	notch 3	0.072
FGF1	fibroblast growth factor 1 (acidic)	0.069
SETD8	SET domain containing (lysine methyltransferase) 8	0.068
TNNT1	troponin T type 1 (skeletal, slow)	0.068	Human
FGF10	fibroblast growth factor 10	0.068
LDB3	LIM domain binding 3	0.067
CXXC5	CXXC finger protein 5	0.067
MYOG	myogenin (myogenic factor 4)	0.062
COL4A2	collagen, type IV, alpha 2	0.062
ACTN1	actinin, alpha 1	0.061
ACTN3	actinin, alpha 3	0.060
WNT3A	wingless-type MMTV integration site family, member 3A	0.059
MYBPC1	myosin binding protein C, slow type	0.059
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.059
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.057
CALD1	caldesmon 1	0.056
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.056	Mouse
HAP1	huntingtin-associated protein 1	0.056
KRT14	keratin 14	0.055
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.054
TNNC2	troponin C type 2 (fast)	0.051	Human
PKP2	plakophilin 2	0.051
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.051
PAX8	paired box 8	0.049
MAML1	mastermind-like 1 (Drosophila)	0.049
MYBPH	myosin binding protein H	0.047
COL5A2	collagen, type V, alpha 2	0.046
COL1A1	collagen, type I, alpha 1	0.044
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.042	Human
KRT18	keratin 18	0.039
GATA2	GATA binding protein 2	0.039
MARK3	MAP/microtubule affinity-regulating kinase 3	0.039
MYH4	myosin, heavy chain 4, skeletal muscle	0.038	Human
KRT8	keratin 8	0.038
CNN1	calponin 1, basic, smooth muscle	0.038
EPAS1	endothelial PAS domain protein 1	0.035
TAGLN	transgelin	0.035
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.034
FLNB	filamin B, beta	0.034
HIC1	hypermethylated in cancer 1	0.032
ACTC1	actin, alpha, cardiac muscle 1	0.030
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.029	Human
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.029
RPL3L	ribosomal protein L3-like	0.029
FLNA	filamin A, alpha	0.029
SMAD9	SMAD family member 9	0.028
SFN	stratifin	0.026
PTRF	polymerase I and transcript release factor	0.025
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.025	Human
PDX1	pancreatic and duodenal homeobox 1	0.025
LIN7C	lin-7 homolog C (C. elegans)	0.024
POU4F2	POU class 4 homeobox 2	0.023
RUNX1	runt-related transcription factor 1	0.023
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.022
FRMD5	FERM domain containing 5	0.022
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.022
NCOR2	nuclear receptor corepressor 2	0.022
MYL7	myosin, light chain 7, regulatory	0.021	Human
SMPX	small muscle protein, X-linked	0.021
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.020
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.020
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.020
SOX7	SRY (sex determining region Y)-box 7	0.020
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.019
CAV3	caveolin 3	0.018
NCOA1	nuclear receptor coactivator 1	0.018
RAPSN	receptor-associated protein of the synapse	0.018
HAND2	heart and neural crest derivatives expressed 2	0.018	Human
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.018
LAD1	ladinin 1	0.017
MED10	mediator complex subunit 10	0.017
DSC2	desmocollin 2	0.017
WNT5A	wingless-type MMTV integration site family, member 5A	0.017	Mouse
GATA4	GATA binding protein 4	0.017	Zebrafish
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.017
DSG2	desmoglein 2	0.017
LRRK2	leucine-rich repeat kinase 2	0.016
LAMB1	laminin, beta 1	0.016
EGLN3	egl nine homolog 3 (C. elegans)	0.016
TGFBR1	transforming growth factor, beta receptor 1	0.016
HIST2H3C	histone cluster 2, H3c	0.016
VCL	vinculin	0.016
AXIN1	axin 1	0.015
FGFR1	fibroblast growth factor receptor 1	0.015
CASQ2	calsequestrin 2 (cardiac muscle)	0.015
CDX2	caudal type homeobox 2	0.015
FZD1	frizzled homolog 1 (Drosophila)	0.015	Mouse
CNN2	calponin 2	0.015
ATXN1L	ataxin 1-like	0.015
COL6A3	collagen, type VI, alpha 3	0.015
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.015
RIPK3	receptor-interacting serine-threonine kinase 3	0.015
CYR61	cysteine-rich, angiogenic inducer, 61	0.015
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.014
CTGF	connective tissue growth factor	0.014
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.013
MYLK2	myosin light chain kinase 2	0.013
CAV2	caveolin 2	0.013
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.013
TBX1	T-box 1	0.013
PHOX2A	paired-like homeobox 2a	0.013
SMAD6	SMAD family member 6	0.013
POSTN	periostin, osteoblast specific factor	0.013
MED25	mediator complex subunit 25	0.013
HNF4A	hepatocyte nuclear factor 4, alpha	0.013
LOX	lysyl oxidase	0.013
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.013
SIX6	SIX homeobox 6	0.013
FOXA2	forkhead box A2	0.013
CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.012
LMO1	LIM domain only 1 (rhombotin 1)	0.012
SMAD2	SMAD family member 2	0.012
MYF5	myogenic factor 5	0.012	Mouse
PAX7	paired box 7	0.012	Mouse
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.012
FGF7	fibroblast growth factor 7	0.012
PALLD	palladin, cytoskeletal associated protein	0.012
YAP1	Yes-associated protein 1	0.012
LHX5	LIM homeobox 5	0.012
SOX11	SRY (sex determining region Y)-box 11	0.012
SRPK3	SRSF protein kinase 3	0.012
NPPB	natriuretic peptide B	0.012
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.012
AKAP6	A kinase (PRKA) anchor protein 6	0.011
PGAM2	phosphoglycerate mutase 2 (muscle)	0.011
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.011
MYPN	myopalladin	0.011
MYF6	myogenic factor 6 (herculin)	0.011	Mouse
HOXD12	homeobox D12	0.011
KRT5	keratin 5	0.011
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.011
ZFPM1	zinc finger protein, multitype 1	0.011	Human Mouse
CAPN3	calpain 3, (p94)	0.011
PKD2L1	polycystic kidney disease 2-like 1	0.011
SKIL	SKI-like oncogene	0.011
SYNPO2L	synaptopodin 2-like	0.011
NSFL1C	NSFL1 (p97) cofactor (p47)	0.011
NEUROG3	neurogenin 3	0.011	Human
PAX2	paired box 2	0.011
ATXN3	ataxin 3	0.011
MB	myoglobin	0.010
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.010	Human
PKP4	plakophilin 4	0.010	Human