IMP: Integrative Multi-species Prediction

Homo sapiens

4 genes annotated in human

Multi-species View

cd4 positive alpha beta t cell cytokine production

GO:0035743

Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cd4 positive alpha beta t cell cytokine production"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cd4 positive alpha beta t cell cytokine production" (in gray)

Name	Description	Probability	Func Analog Organism
NUMB	numb homolog (Drosophila)	1.000
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.894
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.887
IL4R	interleukin 4 receptor	0.866
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.843
ZNF71	zinc finger protein 71	0.741
CCDC115	coiled-coil domain containing 115	0.676
CPD	carboxypeptidase D	0.450
CD164	CD164 molecule, sialomucin	0.404
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.319
VHL	von Hippel-Lindau tumor suppressor	0.317
IFNA17	interferon, alpha 17	0.313
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.306
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.264
F11R	F11 receptor	0.190
IFNA4	interferon, alpha 4	0.170
TM9SF2	transmembrane 9 superfamily member 2	0.114
NMT2	N-myristoyltransferase 2	0.112
LBP	lipopolysaccharide binding protein	0.107
ADAM10	ADAM metallopeptidase domain 10	0.099
SNAP23	synaptosomal-associated protein, 23kDa	0.093
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.090
WWC1	WW and C2 domain containing 1	0.085
IFNA10	interferon, alpha 10	0.083	Human
CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.082
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.072
IFNA14	interferon, alpha 14	0.069
IL13RA1	interleukin 13 receptor, alpha 1	0.062
CYLC1	cylicin, basic protein of sperm head cytoskeleton 1	0.057
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.055
GYPB	glycophorin B (MNS blood group)	0.055
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.051
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.051
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.051
IFNA16	interferon, alpha 16	0.049	Human
SERINC1	serine incorporator 1	0.047
PICALM	phosphatidylinositol binding clathrin assembly protein	0.047
IFIT2	interferon-induced protein with tetratricopeptide repeats 2	0.046
IFNA21	interferon, alpha 21	0.045	Human
IFNB1	interferon, beta 1, fibroblast	0.045
IFNA2	interferon, alpha 2	0.041
OASL	2'-5'-oligoadenylate synthetase-like	0.041
IFNA13	interferon, alpha 13	0.041
IL2	interleukin 2	0.039
CXCL11	chemokine (C-X-C motif) ligand 11	0.038
IL9	interleukin 9	0.037
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.034
EPSTI1	epithelial stromal interaction 1 (breast)	0.033
C6orf10	chromosome 6 open reading frame 10	0.033
PRKCI	protein kinase C, iota	0.032
IAPP	islet amyloid polypeptide	0.032
SPO11	SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)	0.031
LECT2	leukocyte cell-derived chemotaxin 2	0.031
RAB1A	RAB1A, member RAS oncogene family	0.031
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.031
COLEC10	collectin sub-family member 10 (C-type lectin)	0.030
NMBR	neuromedin B receptor	0.030
KEAP1	kelch-like ECH-associated protein 1	0.029
SEMG2	semenogelin II	0.028
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	0.028
RRH	retinal pigment epithelium-derived rhodopsin homolog	0.027
SOCS1	suppressor of cytokine signaling 1	0.027
IL21	interleukin 21	0.026
AFM	afamin	0.026
TAS2R8	taste receptor, type 2, member 8	0.026
FGL1	fibrinogen-like 1	0.025
ANGPTL3	angiopoietin-like 3	0.025
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.024
IFNA5	interferon, alpha 5	0.024	Human
TRIM48	tripartite motif containing 48	0.023
IFNA8	interferon, alpha 8	0.023	Human
C4BPB	complement component 4 binding protein, beta	0.023
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.023
IFI44L	interferon-induced protein 44-like	0.023
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.023
ANXA4	annexin A4	0.022
TAS2R7	taste receptor, type 2, member 7	0.022
TAS2R16	taste receptor, type 2, member 16	0.022
RIOK3	RIO kinase 3 (yeast)	0.022
PDPK1	3-phosphoinositide dependent protein kinase-1	0.021
OR5P2	olfactory receptor, family 5, subfamily P, member 2	0.021
OR2B2	olfactory receptor, family 2, subfamily B, member 2	0.021
ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2	0.021
FSHR	follicle stimulating hormone receptor	0.021
CYLC2	cylicin, basic protein of sperm head cytoskeleton 2	0.020
GLYAT	glycine-N-acyltransferase	0.020
SERINC3	serine incorporator 3	0.020
CLDN17	claudin 17	0.020
OR7A10	olfactory receptor, family 7, subfamily A, member 10	0.020
IMPG1	interphotoreceptor matrix proteoglycan 1	0.020
GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	0.019
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.019
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.019
SCARB2	scavenger receptor class B, member 2	0.019
LRRK2	leucine-rich repeat kinase 2	0.019
SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.018
TSHB	thyroid stimulating hormone, beta	0.018
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.018
SETD7	SET domain containing (lysine methyltransferase) 7	0.018
PMP2	peripheral myelin protein 2	0.018
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.018
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.018
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.018
HTN3	histatin 3	0.018
OR52A1	olfactory receptor, family 52, subfamily A, member 1	0.018
GCG	glucagon	0.017
HTN1	histatin 1	0.017
PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.017
OR51B2	olfactory receptor, family 51, subfamily B, member 2	0.017
IFI27	interferon, alpha-inducible protein 27	0.017
CCR9	chemokine (C-C motif) receptor 9	0.017
LALBA	lactalbumin, alpha-	0.017
FGB	fibrinogen beta chain	0.017
FABP2	fatty acid binding protein 2, intestinal	0.017
SIRT6	sirtuin 6	0.017
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.017
TMEM59	transmembrane protein 59	0.017
PLSCR2	phospholipid scramblase 2	0.017
GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.016
APCS	amyloid P component, serum	0.016
ACSL1	acyl-CoA synthetase long-chain family member 1	0.016
OTC	ornithine carbamoyltransferase	0.016
TMEM212	transmembrane protein 212	0.016
HYAL4	hyaluronoglucosaminidase 4	0.016
F13B	coagulation factor XIII, B polypeptide	0.016
SI	sucrase-isomaltase (alpha-glucosidase)	0.016
OR10H3	olfactory receptor, family 10, subfamily H, member 3	0.016
FGA	fibrinogen alpha chain	0.016
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.016
HERC5	hect domain and RLD 5	0.016
REG1A	regenerating islet-derived 1 alpha	0.016
PDC	phosducin	0.016
AKAP4	A kinase (PRKA) anchor protein 4	0.016
CSN3	casein kappa	0.015
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.015
HRG	histidine-rich glycoprotein	0.015
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.015
C9	complement component 9	0.015
HSD3B2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.015
GDE1	glycerophosphodiester phosphodiesterase 1	0.015
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.015
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.015
CRISP1	cysteine-rich secretory protein 1	0.015
ZNF157	zinc finger protein 157	0.015
PDE6C	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.015
GPR22	G protein-coupled receptor 22	0.015
MBL2	mannose-binding lectin (protein C) 2, soluble	0.015
CXorf59	chromosome X open reading frame 59	0.015
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.015
STATH	statherin	0.015
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.015
HNF4G	hepatocyte nuclear factor 4, gamma	0.015
ANP32C	acidic (leucine-rich) nuclear phosphoprotein 32 family, member C	0.015
OR1D2	olfactory receptor, family 1, subfamily D, member 2	0.015
ADAM2	ADAM metallopeptidase domain 2	0.015
SLCO1B1	solute carrier organic anion transporter family, member 1B1	0.015
ANXA10	annexin A10	0.015
CCDC54	coiled-coil domain containing 54	0.015
LIPF	lipase, gastric	0.015
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.015
AOC2	amine oxidase, copper containing 2 (retina-specific)	0.015
SEMG1	semenogelin I	0.015
FGG	fibrinogen gamma chain	0.015
ARG1	arginase, liver	0.015
S100G	S100 calcium binding protein G	0.014
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.014
AMELY	amelogenin, Y-linked	0.014
CTNNA3	catenin (cadherin-associated protein), alpha 3	0.014
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.014
CA1	carbonic anhydrase I	0.014
F9	coagulation factor IX	0.014
POU1F1	POU class 1 homeobox 1	0.014
ASB4	ankyrin repeat and SOCS box containing 4	0.014
HIST1H3J	histone cluster 1, H3j	0.014
CFHR4	complement factor H-related 4	0.014
MS4A5	membrane-spanning 4-domains, subfamily A, member 5	0.014
GNS	glucosamine (N-acetyl)-6-sulfatase	0.014
CSNK2B	casein kinase 2, beta polypeptide	0.014
TMPRSS11B	transmembrane protease, serine 11B	0.014
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.014
AADAC	arylacetamide deacetylase (esterase)	0.014
ZNF81	zinc finger protein 81	0.014
SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10	0.014
PNLIP	pancreatic lipase	0.014
C1orf129	chromosome 1 open reading frame 129	0.013
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.013
HTR3B	5-hydroxytryptamine (serotonin) receptor 3B	0.013
PSG2	pregnancy specific beta-1-glycoprotein 2	0.013
BAD	BCL2-associated agonist of cell death	0.013
SLC22A13	solute carrier family 22 (organic anion transporter), member 13	0.013
LUZP4	leucine zipper protein 4	0.013
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.013
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	0.013
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.013
ODAM	odontogenic, ameloblast asssociated	0.013
IFIH1	interferon induced with helicase C domain 1	0.013
DPPA4	developmental pluripotency associated 4	0.013
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.013
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.013
UBXN4	UBX domain protein 4	0.013
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.013
PRODH2	proline dehydrogenase (oxidase) 2	0.013
CLEC1B	C-type lectin domain family 1, member B	0.013
SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2	0.013
ART4	ADP-ribosyltransferase 4 (Dombrock blood group)	0.013
PTH	parathyroid hormone	0.013
MAPK14	mitogen-activated protein kinase 14	0.013
CSN1S1	casein alpha s1	0.013
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.013
DEFB126	defensin, beta 126	0.013
DSPP	dentin sialophosphoprotein	0.012
GYPE	glycophorin E (MNS blood group)	0.012
CAT	catalase	0.012
TM4SF20	transmembrane 4 L six family member 20	0.012
IL4	interleukin 4	0.012
PGRMC1	progesterone receptor membrane component 1	0.012
CDH9	cadherin 9, type 2 (T1-cadherin)	0.012
CSN2	casein beta	0.012
TRPC7	transient receptor potential cation channel, subfamily C, member 7	0.012
PARP4	poly (ADP-ribose) polymerase family, member 4	0.012
CLDN16	claudin 16	0.012
AFP	alpha-fetoprotein	0.012
OCLM	oculomedin	0.012
IFNA7	interferon, alpha 7	0.012	Human
RNFT1	ring finger protein, transmembrane 1	0.012
TAAR2	trace amine associated receptor 2	0.012
RGSL1	regulator of G-protein signaling like 1	0.012
SPRR2B	small proline-rich protein 2B	0.012
ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	0.012
KIR2DL4	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4	0.012
ADAM9	ADAM metallopeptidase domain 9	0.012
GNRHR	gonadotropin-releasing hormone receptor	0.012
MMP27	matrix metallopeptidase 27	0.012
AMELX	amelogenin, X-linked	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
IFNA6	interferon, alpha 6	0.012	Human
IFI44	interferon-induced protein 44	0.012
SAMD9L	sterile alpha motif domain containing 9-like	0.012
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.012
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.012
MORC1	MORC family CW-type zinc finger 1	0.012
PRDM5	PR domain containing 5	0.012
OLAH	oleoyl-ACP hydrolase	0.012
ORM2	orosomucoid 2	0.012
RFPL1	ret finger protein-like 1	0.012
TAS2R9	taste receptor, type 2, member 9	0.012
GLRA3	glycine receptor, alpha 3	0.011
USP26	ubiquitin specific peptidase 26	0.011
MIA2	melanoma inhibitory activity 2	0.011
SPATA16	spermatogenesis associated 16	0.011
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.011
ZNF280A	zinc finger protein 280A	0.011
IL1F5	interleukin 1 family, member 5 (delta)	0.011
MTMR7	myotubularin related protein 7	0.011
ADAM21	ADAM metallopeptidase domain 21	0.011
KRTAP1-1	keratin associated protein 1-1	0.011
LHCGR	luteinizing hormone/choriogonadotropin receptor	0.011
CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22	0.011
CST1	cystatin SN	0.011
IFNA1	interferon, alpha 1	0.011	Human
BPY2	basic charge, Y-linked, 2	0.011
EDDM3A	epididymal protein 3A	0.011
EPYC	epiphycan	0.011
GYPA	glycophorin A (MNS blood group)	0.011
TAAR1	trace amine associated receptor 1	0.011
SPINK1	serine peptidase inhibitor, Kazal type 1	0.011
LRRC31	leucine rich repeat containing 31	0.011
KIF24	kinesin family member 24	0.011
MAT1A	methionine adenosyltransferase I, alpha	0.011
KERA	keratocan	0.011
LPAR4	lysophosphatidic acid receptor 4	0.011
HESX1	HESX homeobox 1	0.011
CCL1	chemokine (C-C motif) ligand 1	0.011
C11orf40	chromosome 11 open reading frame 40	0.011
CRYGB	crystallin, gamma B	0.011
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.011
ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.011
SPIC	Spi-C transcription factor (Spi-1/PU.1 related)	0.011
MMP20	matrix metallopeptidase 20	0.011
IL26	interleukin 26	0.011
RLN1	relaxin 1	0.011
MC4R	melanocortin 4 receptor	0.011
ALX1	ALX homeobox 1	0.011
SMR3A	submaxillary gland androgen regulated protein 3A	0.011
SLC25A21	solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21	0.011
PLA2G1B	phospholipase A2, group IB (pancreas)	0.011
IL17A	interleukin 17A	0.011
IMPG2	interphotoreceptor matrix proteoglycan 2	0.011
OR5I1	olfactory receptor, family 5, subfamily I, member 1	0.011
CXorf1	chromosome X open reading frame 1	0.011
CTAGE1	cutaneous T-cell lymphoma-associated antigen 1	0.011
HRH4	histamine receptor H4	0.010
SMR3B	submaxillary gland androgen regulated protein 3B	0.010
CCR8	chemokine (C-C motif) receptor 8	0.010
GPRC6A	G protein-coupled receptor, family C, group 6, member A	0.010
CPB2	carboxypeptidase B2 (plasma)	0.010
BAGE	B melanoma antigen	0.010
SLC25A31	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31	0.010
GPR45	G protein-coupled receptor 45	0.010
SNTG1	syntrophin, gamma 1	0.010
SCN11A	sodium channel, voltage-gated, type XI, alpha subunit	0.010
NEU3	sialidase 3 (membrane sialidase)	0.010
CXCR1	chemokine (C-X-C motif) receptor 1	0.010
SLC13A1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.010
WFDC8	WAP four-disulfide core domain 8	0.010
INSL4	insulin-like 4 (placenta)	0.010
PTTG2	pituitary tumor-transforming 2	0.010
KRTAP1-5	keratin associated protein 1-5	0.010
SSX3	synovial sarcoma, X breakpoint 3	0.010
SPAM1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	0.010
GLIPR1L1	GLI pathogenesis-related 1 like 1	0.010
OR7E24	olfactory receptor, family 7, subfamily E, member 24	0.010
VIP	vasoactive intestinal peptide	0.010
COL19A1	collagen, type XIX, alpha 1	0.010
NOX3	NADPH oxidase 3	0.010
SSX5	synovial sarcoma, X breakpoint 5	0.010
KRT25	keratin 25	0.010
KNG1	kininogen 1	0.010
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.010
PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.010
KRT12	keratin 12	0.010
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.010
PROL1	proline rich, lacrimal 1	0.010
CNTN6	contactin 6	0.010
OMG	oligodendrocyte myelin glycoprotein	0.010
APOC4	apolipoprotein C-IV	0.010
IL23R	interleukin 23 receptor	0.010