IMP
Process View
negative regulation of pathway restricted smad protein phosphorylation
Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of pathway restricted smad protein phosphorylation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SMAD1 | SMAD family member 1 | 1.000 | Human | |
| SMAD2 | SMAD family member 2 | 0.999 | Human | |
| SMAD7 | SMAD family member 7 | 0.995 | ||
| SMAD3 | SMAD family member 3 | 0.992 | Human | |
| TGFB1 | transforming growth factor, beta 1 | 0.984 | ||
| SMAD5 | SMAD family member 5 | 0.960 | Human | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.957 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.952 | ||
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.679 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.597 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.549 | ||
| SMAD4 | SMAD family member 4 | 0.399 | Human | |
| SNRPE | small nuclear ribonucleoprotein polypeptide E | 0.359 | ||
| CXXC5 | CXXC finger protein 5 | 0.219 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.119 | ||
| SMAD6 | SMAD family member 6 | 0.097 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.087 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.078 | ||
| RHOA | ras homolog gene family, member A | 0.071 | ||
| SOX7 | SRY (sex determining region Y)-box 7 | 0.069 | ||
| MKL2 | MKL/myocardin-like 2 | 0.062 | ||
| BMP2 | bone morphogenetic protein 2 | 0.045 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.043 | ||
| RNF11 | ring finger protein 11 | 0.038 | ||
| VPS24 | vacuolar protein sorting 24 homolog (S. cerevisiae) | 0.037 | ||
| SMAD9 | SMAD family member 9 | 0.035 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.034 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.034 | ||
| FSTL1 | follistatin-like 1 | 0.030 | ||
| DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.029 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.028 | ||
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.025 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.024 | ||
| YAP1 | Yes-associated protein 1 | 0.023 | ||
| TFPI2 | tissue factor pathway inhibitor 2 | 0.020 | ||
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.019 | ||
| SKIL | SKI-like oncogene | 0.018 | ||
| GMEB1 | glucocorticoid modulatory element binding protein 1 | 0.017 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.017 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.017 | ||
| BMP7 | bone morphogenetic protein 7 | 0.016 | ||
| STAMBP | STAM binding protein | 0.016 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.016 | ||
| RNFT1 | ring finger protein, transmembrane 1 | 0.015 | ||
| AR | androgen receptor | 0.015 | ||
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.015 | ||
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.015 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.015 | ||
| ICK | intestinal cell (MAK-like) kinase | 0.014 | ||
| ING2 | inhibitor of growth family, member 2 | 0.013 | ||
| WDYHV1 | WDYHV motif containing 1 | 0.013 | ||
| RNF146 | ring finger protein 146 | 0.013 | ||
| NRP1 | neuropilin 1 | 0.012 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.012 | ||
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.011 | ||
| CHERP | calcium homeostasis endoplasmic reticulum protein | 0.011 | ||
| FLNB | filamin B, beta | 0.011 | ||
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 0.011 |