IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

cell fate determination

A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell fate determination"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cell fate determination" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	1.000	Worm Fly
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	1.000	Worm Fly
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	1.000	Worm Fly
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1.000	Mouse Worm Fly
NOTCH1	notch 1	0.999	Fly
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.999	Worm Fly
POU3F2	POU class 3 homeobox 2	0.997	Human
CFLAR	CASP8 and FADD-like apoptosis regulator	0.996
JAG1	jagged 1	0.994
FGF1	fibroblast growth factor 1 (acidic)	0.993
SP1	Sp1 transcription factor	0.990
APC	adenomatous polyposis coli	0.990
SMAD4	SMAD family member 4	0.990
ATXN1	ataxin 1	0.989
MAPT	microtubule-associated protein tau	0.986
SFN	stratifin	0.983	Fly
TP53	tumor protein p53	0.979
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.968	Fly
FOXD3	forkhead box D3	0.961
PAX3	paired box 3	0.953
SMAD7	SMAD family member 7	0.952
HDAC4	histone deacetylase 4	0.948
RACGAP1	Rac GTPase activating protein 1	0.943	Fly
TAL1	T-cell acute lymphocytic leukemia 1	0.936
GSK3B	glycogen synthase kinase 3 beta	0.929
HIC1	hypermethylated in cancer 1	0.927
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.920
CDK2	cyclin-dependent kinase 2	0.920
PKP2	plakophilin 2	0.914
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.904	Worm Fly
CSNK1E	casein kinase 1, epsilon	0.897
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.891
NCOR1	nuclear receptor corepressor 1	0.880
FADD	Fas (TNFRSF6)-associated via death domain	0.879
POU5F1	POU class 5 homeobox 1	0.874
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.858
SMAD2	SMAD family member 2	0.850
SOX2	SRY (sex determining region Y)-box 2	0.838	Human
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.798
KIF23	kinesin family member 23	0.798	Fly
ECT2	epithelial cell transforming sequence 2 oncogene	0.773	Worm
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.770
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.770
ITGB4	integrin, beta 4	0.762
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.747
MBD3	methyl-CpG binding domain protein 3	0.745
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.739
FKBP1A	FK506 binding protein 1A, 12kDa	0.734
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.723
TCF4	transcription factor 4	0.696
KIF5B	kinesin family member 5B	0.682
RBPMS	RNA binding protein with multiple splicing	0.682
JUP	junction plakoglobin	0.665	Worm Fly
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.664
SPTBN1	spectrin, beta, non-erythrocytic 1	0.662
PRKCI	protein kinase C, iota	0.653
HIPK2	homeodomain interacting protein kinase 2	0.651
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.644
MTA2	metastasis associated 1 family, member 2	0.633
TGIF1	TGFB-induced factor homeobox 1	0.631
SOX1	SRY (sex determining region Y)-box 1	0.611	Human
FAM46A	family with sequence similarity 46, member A	0.606
SMAD9	SMAD family member 9	0.593
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.578
MARK2	MAP/microtubule affinity-regulating kinase 2	0.573	Worm
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.570
CDK11B	cyclin-dependent kinase 11B	0.567
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.566
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.564
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.563	Mouse
CXXC5	CXXC finger protein 5	0.562
PAX6	paired box 6	0.558	Mouse
SMAD3	SMAD family member 3	0.558
SOX11	SRY (sex determining region Y)-box 11	0.552	Human
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.550
LHX3	LIM homeobox 3	0.522	Human
ATF7IP	activating transcription factor 7 interacting protein	0.521
POU3F3	POU class 3 homeobox 3	0.506	Human
CBX5	chromobox homolog 5	0.502
SOX21	SRY (sex determining region Y)-box 21	0.499
HNF4A	hepatocyte nuclear factor 4, alpha	0.497
RAX	retina and anterior neural fold homeobox	0.488
HCFC1	host cell factor C1 (VP16-accessory protein)	0.483
NOTCH3	notch 3	0.478	Fly
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.467
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.466	Fly
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.457
MTA1	metastasis associated 1	0.457
OTP	orthopedia homeobox	0.456
AXIN1	axin 1	0.449
WT1	Wilms tumor 1	0.440
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.439
LMX1A	LIM homeobox transcription factor 1, alpha	0.438	Human
OLIG2	oligodendrocyte lineage transcription factor 2	0.431	Zebrafish
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.422
STK11	serine/threonine kinase 11	0.420	Worm
SKIL	SKI-like oncogene	0.412
HTT	huntingtin	0.409
PIAS1	protein inhibitor of activated STAT, 1	0.407
BBS10	Bardet-Biedl syndrome 10	0.397
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.392
DAZAP2	DAZ associated protein 2	0.383
FOXA2	forkhead box A2	0.380
GMFB	glia maturation factor, beta	0.378
DLL1	delta-like 1 (Drosophila)	0.377
TNIK	TRAF2 and NCK interacting kinase	0.368
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.365
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.363
TBX2	T-box 2	0.359
PDX1	pancreatic and duodenal homeobox 1	0.357
LHX1	LIM homeobox 1	0.356	Human
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.356
EGR1	early growth response 1	0.354
CTNNBIP1	catenin, beta interacting protein 1	0.343
PIAS4	protein inhibitor of activated STAT, 4	0.338
SKP2	S-phase kinase-associated protein 2 (p45)	0.337
CDK1	cyclin-dependent kinase 1	0.336
GATA4	GATA binding protein 4	0.331	Fly
TBX5	T-box 5	0.331
ERBB2IP	erbb2 interacting protein	0.328
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.327
STRADB	STE20-related kinase adaptor beta	0.322
PAX2	paired box 2	0.319	Mouse
HDAC7	histone deacetylase 7	0.317
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.310
E2F1	E2F transcription factor 1	0.304
MSX1	msh homeobox 1	0.298
PAX7	paired box 7	0.298
SOX13	SRY (sex determining region Y)-box 13	0.297
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.291
FBLN1	fibulin 1	0.290
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.287
CADM4	cell adhesion molecule 4	0.286
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.284
CTBP1	C-terminal binding protein 1	0.283	Fly
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.282
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.281	Fly
MAML1	mastermind-like 1 (Drosophila)	0.279
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.277
INCENP	inner centromere protein antigens 135/155kDa	0.272
BCL2	B-cell CLL/lymphoma 2	0.271
JAG2	jagged 2	0.264
ZNF512B	zinc finger protein 512B	0.260
PML	promyelocytic leukemia	0.260
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.259
INHBB	inhibin, beta B	0.258
NOVA2	neuro-oncological ventral antigen 2	0.254
HOXD12	homeobox D12	0.252
RBBP8	retinoblastoma binding protein 8	0.252
GBX2	gastrulation brain homeobox 2	0.251
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.247	Fly
CDH5	cadherin 5, type 2 (vascular endothelium)	0.245
ARID1A	AT rich interactive domain 1A (SWI-like)	0.243
MYOD1	myogenic differentiation 1	0.243	Mouse
MARCKSL1	MARCKS-like 1	0.242
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.237
POU3F1	POU class 3 homeobox 1	0.232	Human
CUL2	cullin 2	0.230
CHD4	chromodomain helicase DNA binding protein 4	0.230	Worm
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.226
SIX3	SIX homeobox 3	0.215
GLIS2	GLIS family zinc finger 2	0.215
LAPTM5	lysosomal protein transmembrane 5	0.214
RAD54B	RAD54 homolog B (S. cerevisiae)	0.212
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.211
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	0.210
JAM2	junctional adhesion molecule 2	0.208
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.207
RB1	retinoblastoma 1	0.203
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.202
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.197
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.197	Fly
FGF8	fibroblast growth factor 8 (androgen-induced)	0.197
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.194
DLL3	delta-like 3 (Drosophila)	0.192
YAP1	Yes-associated protein 1	0.192
FOXG1	forkhead box G1	0.189	Mouse
C9orf100	chromosome 9 open reading frame 100	0.188
PRKD2	protein kinase D2	0.188
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.187
RHOXF2	Rhox homeobox family, member 2	0.187
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.185	Fly
ARF6	ADP-ribosylation factor 6	0.183
CCNE1	cyclin E1	0.182	Fly
NLK	nemo-like kinase	0.179	Worm
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.179
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.177
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.177
PRKCZ	protein kinase C, zeta	0.176
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.176
TP73	tumor protein p73	0.174
PUM1	pumilio homolog 1 (Drosophila)	0.174
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.173
CCND1	cyclin D1	0.172
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.172
SALL2	sal-like 2 (Drosophila)	0.172
MNX1	motor neuron and pancreas homeobox 1	0.168
ZMYND8	zinc finger, MYND-type containing 8	0.167
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.165
ASB2	ankyrin repeat and SOCS box containing 2	0.163
TBX1	T-box 1	0.161
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.161
VSX2	visual system homeobox 2	0.160
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.160	Mouse
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.158
RBL1	retinoblastoma-like 1 (p107)	0.158
LBX1	ladybird homeobox 1	0.158	Mouse
SREBF2	sterol regulatory element binding transcription factor 2	0.158
TLX2	T-cell leukemia homeobox 2	0.155
NKX2-2	NK2 homeobox 2	0.154	Mouse
RALGDS	ral guanine nucleotide dissociation stimulator	0.154
NKX6-1	NK6 homeobox 1	0.154
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.153
FOXL1	forkhead box L1	0.152
CORO1C	coronin, actin binding protein, 1C	0.152
CSNK1D	casein kinase 1, delta	0.152
SFRP5	secreted frizzled-related protein 5	0.151
CEP164	centrosomal protein 164kDa	0.151
OTX2	orthodenticle homeobox 2	0.151	Mouse
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.150
CLIP1	CAP-GLY domain containing linker protein 1	0.148
FGF2	fibroblast growth factor 2 (basic)	0.148
CCNA2	cyclin A2	0.148
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.147
SRI	sorcin	0.146
PKP3	plakophilin 3	0.146
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.145
SFRP1	secreted frizzled-related protein 1	0.145
GPSM2	G-protein signaling modulator 2	0.144
OPRD1	opioid receptor, delta 1	0.144
YY1	YY1 transcription factor	0.144
BMP7	bone morphogenetic protein 7	0.143
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.141	Fly
CCNB2	cyclin B2	0.141
LHX2	LIM homeobox 2	0.141	Human
FGF10	fibroblast growth factor 10	0.140
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.140
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.139
TDP2	tyrosyl-DNA phosphodiesterase 2	0.139
RCOR1	REST corepressor 1	0.139
SOX10	SRY (sex determining region Y)-box 10	0.138	Human
CDX2	caudal type homeobox 2	0.137
PEBP4	phosphatidylethanolamine-binding protein 4	0.137
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.135
HDAC9	histone deacetylase 9	0.130
HIPK3	homeodomain interacting protein kinase 3	0.129
SIX5	SIX homeobox 5	0.129
SAFB	scaffold attachment factor B	0.127
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.127
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.127
SIX6	SIX homeobox 6	0.127
SALL3	sal-like 3 (Drosophila)	0.127
DCK	deoxycytidine kinase	0.127
POU4F1	POU class 4 homeobox 1	0.127	Human
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.127
ATXN1L	ataxin 1-like	0.126
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.125	Worm
HES2	hairy and enhancer of split 2 (Drosophila)	0.125	Fly
BTBD2	BTB (POZ) domain containing 2	0.125
SIX2	SIX homeobox 2	0.124
SOX3	SRY (sex determining region Y)-box 3	0.123	Human
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.123
FAM110C	family with sequence similarity 110, member C	0.123
KDM1A	lysine (K)-specific demethylase 1A	0.122
PYY	peptide YY	0.122
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.122
WNT6	wingless-type MMTV integration site family, member 6	0.121
PITX3	paired-like homeodomain 3	0.120
NOTCH2NL	notch 2 N-terminal like	0.120
RAB11FIP3	RAB11 family interacting protein 3 (class II)	0.119	Fly
POU3F4	POU class 3 homeobox 4	0.119	Human
NEUROD2	neurogenic differentiation 2	0.119
BHLHE23	basic helix-loop-helix family, member e23	0.119
BZW1	basic leucine zipper and W2 domains 1	0.118
HOXB13	homeobox B13	0.117
DLX4	distal-less homeobox 4	0.116
RIN1	Ras and Rab interactor 1	0.116
BMP4	bone morphogenetic protein 4	0.116	Mouse
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.115	Fly
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.114
C1QL1	complement component 1, q subcomponent-like 1	0.114
NOTCH2	notch 2	0.114	Rat Fly
GAS2L3	growth arrest-specific 2 like 3	0.113
FOXH1	forkhead box H1	0.113
HOXD1	homeobox D1	0.113
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.112
VAX2	ventral anterior homeobox 2	0.112
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.112	Worm
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.111
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.111
GATA5	GATA binding protein 5	0.111	Fly
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.110
WNT10A	wingless-type MMTV integration site family, member 10A	0.110
BIRC5	baculoviral IAP repeat containing 5	0.110
DCX	doublecortin	0.110
GFAP	glial fibrillary acidic protein	0.110
ZBTB8A	zinc finger and BTB domain containing 8A	0.109
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.108
ISL1	ISL LIM homeobox 1	0.108
MAP2K1	mitogen-activated protein kinase kinase 1	0.108
ONECUT1	one cut homeobox 1	0.108
FOXB1	forkhead box B1	0.107
NKX2-1	NK2 homeobox 1	0.107
NEUROD1	neurogenic differentiation 1	0.106
HOXD3	homeobox D3	0.106
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.106
LHX5	LIM homeobox 5	0.105	Human
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.104
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.104
FOXF1	forkhead box F1	0.104
PAX8	paired box 8	0.103
JPH3	junctophilin 3	0.103
CHD6	chromodomain helicase DNA binding protein 6	0.103
FYN	FYN oncogene related to SRC, FGR, YES	0.103
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.102
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.102	Fly
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.102
SMAD1	SMAD family member 1	0.101
ALX4	ALX homeobox 4	0.101
FOXN4	forkhead box N4	0.101
TSC2	tuberous sclerosis 2	0.100
EXOC5	exocyst complex component 5	0.100
JAM3	junctional adhesion molecule 3	0.100
FOXC1	forkhead box C1	0.100
COL2A1	collagen, type II, alpha 1	0.099
FAR1	fatty acyl CoA reductase 1	0.099
CDX1	caudal type homeobox 1	0.099
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.099
ARX	aristaless related homeobox	0.099
MAPK8	mitogen-activated protein kinase 8	0.099
POU4F2	POU class 4 homeobox 2	0.098	Human
MARK4	MAP/microtubule affinity-regulating kinase 4	0.098	Worm
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.098
HAND2	heart and neural crest derivatives expressed 2	0.098
TGFBR1	transforming growth factor, beta receptor 1	0.097
NRG2	neuregulin 2	0.097
SOX4	SRY (sex determining region Y)-box 4	0.097	Human
EN2	engrailed homeobox 2	0.097	Fly
NEUROG2	neurogenin 2	0.096
SNAPIN	SNAP-associated protein	0.096
FGFR4	fibroblast growth factor receptor 4	0.096	Fly
EMX1	empty spiracles homeobox 1	0.096
CCND2	cyclin D2	0.096
IFI16	interferon, gamma-inducible protein 16	0.096
PITX2	paired-like homeodomain 2	0.096
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.095	Worm
FGF3	fibroblast growth factor 3	0.095
NCF2	neutrophil cytosolic factor 2	0.094
USP9X	ubiquitin specific peptidase 9, X-linked	0.094
CALCR	calcitonin receptor	0.094
NUMA1	nuclear mitotic apparatus protein 1	0.093
MAP2K4	mitogen-activated protein kinase kinase 4	0.093
NCOR2	nuclear receptor corepressor 2	0.093
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.093
ECEL1	endothelin converting enzyme-like 1	0.093
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.093
SIM2	single-minded homolog 2 (Drosophila)	0.092
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.092
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.092
NFIB	nuclear factor I/B	0.092
VSX1	visual system homeobox 1	0.091
NKX3-2	NK3 homeobox 2	0.091
T	T, brachyury homolog (mouse)	0.091
PRRC2C	proline-rich coiled-coil 2C	0.091
KDM2A	lysine (K)-specific demethylase 2A	0.091
DLX2	distal-less homeobox 2	0.091
DPYSL5	dihydropyrimidinase-like 5	0.090
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.090
DRD4	dopamine receptor D4	0.090
EFNB2	ephrin-B2	0.090
CCNK	cyclin K	0.090
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.089
PITX1	paired-like homeodomain 1	0.089
ALX3	ALX homeobox 3	0.088
FOXF2	forkhead box F2	0.088
SOS1	son of sevenless homolog 1 (Drosophila)	0.088
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.087
LMX1B	LIM homeobox transcription factor 1, beta	0.087	Human
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.086
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.086
JUB	jub, ajuba homolog (Xenopus laevis)	0.086
SOX18	SRY (sex determining region Y)-box 18	0.086	Human
HES1	hairy and enhancer of split 1, (Drosophila)	0.085	Mouse
PAX5	paired box 5	0.085
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.085
KLC1	kinesin light chain 1	0.085
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.084
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.084
BMPR1A	bone morphogenetic protein receptor, type IA	0.083
PRDM13	PR domain containing 13	0.083
CHD7	chromodomain helicase DNA binding protein 7	0.082
KIAA0174	KIAA0174	0.082
ANKRD28	ankyrin repeat domain 28	0.082
CIC	capicua homolog (Drosophila)	0.082
GGN	gametogenetin	0.082
GSX2	GS homeobox 2	0.082
GDNF	glial cell derived neurotrophic factor	0.082
FGF4	fibroblast growth factor 4	0.081
KLF13	Kruppel-like factor 13	0.081
PATZ1	POZ (BTB) and AT hook containing zinc finger 1	0.081
AMOTL2	angiomotin like 2	0.080
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.080
KIAA0889	KIAA0889	0.080
IHH	Indian hedgehog	0.080
POU4F3	POU class 4 homeobox 3	0.080	Human
HOXC13	homeobox C13	0.080
EZR	ezrin	0.080
BICD2	bicaudal D homolog 2 (Drosophila)	0.079	Fly
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.079
HES5	hairy and enhancer of split 5 (Drosophila)	0.079	Mouse Fly
DDR1	discoidin domain receptor tyrosine kinase 1	0.079
EPAS1	endothelial PAS domain protein 1	0.079
NEUROG3	neurogenin 3	0.078
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.078
FEV	FEV (ETS oncogene family)	0.078
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.078
MECOM	MDS1 and EVI1 complex locus	0.077
FZD8	frizzled homolog 8 (Drosophila)	0.077
EVC2	Ellis van Creveld syndrome 2	0.077
NFYA	nuclear transcription factor Y, alpha	0.077
HNF1A	HNF1 homeobox A	0.076
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.076
ONECUT2	one cut homeobox 2	0.076
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.075
SOX9	SRY (sex determining region Y)-box 9	0.075	Human
GPR4	G protein-coupled receptor 4	0.075
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.075
SETD8	SET domain containing (lysine methyltransferase) 8	0.075
ZNF609	zinc finger protein 609	0.074
NEUROG1	neurogenin 1	0.074
NKX2-8	NK2 homeobox 8	0.074
HOXD13	homeobox D13	0.074
TCEA2	transcription elongation factor A (SII), 2	0.074
MBD1	methyl-CpG binding domain protein 1	0.073
ZNF331	zinc finger protein 331	0.073
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	0.073
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.073
CCNE2	cyclin E2	0.073	Fly
BAG1	BCL2-associated athanogene	0.073
TRPS1	trichorhinophalangeal syndrome I	0.073
BRCA1	breast cancer 1, early onset	0.073
CRLF1	cytokine receptor-like factor 1	0.073
FRS2	fibroblast growth factor receptor substrate 2	0.073
WNT4	wingless-type MMTV integration site family, member 4	0.072
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.072
WEE1	WEE1 homolog (S. pombe)	0.072
CDK6	cyclin-dependent kinase 6	0.072
RIMS4	regulating synaptic membrane exocytosis 4	0.072
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.072	Fly
RANBP2	RAN binding protein 2	0.072
ARIH2	ariadne homolog 2 (Drosophila)	0.072
CDT1	chromatin licensing and DNA replication factor 1	0.072
DLX1	distal-less homeobox 1	0.072
C19orf6	chromosome 19 open reading frame 6	0.071
CAMKK1	calcium/calmodulin-dependent protein kinase kinase 1, alpha	0.071
CTGF	connective tissue growth factor	0.071
RFX4	regulatory factor X, 4 (influences HLA class II expression)	0.071
INSM1	insulinoma-associated 1	0.071
STRN3	striatin, calmodulin binding protein 3	0.071
ESPN	espin	0.071
RDX	radixin	0.070
FNBP1	formin binding protein 1	0.070
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.070	Mouse
GCM2	glial cells missing homolog 2 (Drosophila)	0.070
BARX1	BARX homeobox 1	0.069
HOXC11	homeobox C11	0.069
NES	nestin	0.069
EYA2	eyes absent homolog 2 (Drosophila)	0.069
GATAD2B	GATA zinc finger domain containing 2B	0.069
RHEB	Ras homolog enriched in brain	0.069
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.069
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.069
IRX4	iroquois homeobox 4	0.068
MT1A	metallothionein 1A	0.068
FOXM1	forkhead box M1	0.068
SOX8	SRY (sex determining region Y)-box 8	0.068	Human
CEP55	centrosomal protein 55kDa	0.068
EVX1	even-skipped homeobox 1	0.068
HMX3	H6 family homeobox 3	0.068
FHL1	four and a half LIM domains 1	0.068
SOX5	SRY (sex determining region Y)-box 5	0.067
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.067
PAPD7	PAP associated domain containing 7	0.067
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.067	Fly
CLTC	clathrin, heavy chain (Hc)	0.067
LAD1	ladinin 1	0.067
RANBP9	RAN binding protein 9	0.067
FERMT2	fermitin family member 2	0.067
SCARF2	scavenger receptor class F, member 2	0.067
UNCX	UNC homeobox	0.066
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.066
HOXC8	homeobox C8	0.066
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.066
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.066
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.066
IRS2	insulin receptor substrate 2	0.065
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.065
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.065
FOXD2	forkhead box D2	0.065
BHLHE22	basic helix-loop-helix family, member e22	0.064
FOXE3	forkhead box E3	0.064
FLI1	Friend leukemia virus integration 1	0.064
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.064
OTX1	orthodenticle homeobox 1	0.064
THAP11	THAP domain containing 11	0.064
IRF4	interferon regulatory factor 4	0.064
TBC1D5	TBC1 domain family, member 5	0.064
ASB1	ankyrin repeat and SOCS box containing 1	0.064
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.063
WNK1	WNK lysine deficient protein kinase 1	0.063
LINGO3	leucine rich repeat and Ig domain containing 3	0.063
KCTD13	potassium channel tetramerisation domain containing 13	0.063
ACVR2B	activin A receptor, type IIB	0.063
MMD2	monocyte to macrophage differentiation-associated 2	0.063
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.063
HIPK1	homeodomain interacting protein kinase 1	0.063
WNT1	wingless-type MMTV integration site family, member 1	0.063	Mouse
SALL1	sal-like 1 (Drosophila)	0.063
ASB7	ankyrin repeat and SOCS box containing 7	0.063
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.062
CXCR5	chemokine (C-X-C motif) receptor 5	0.062
NBPF10	neuroblastoma breakpoint family, member 10	0.062
HOXA11	homeobox A11	0.062
CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	0.062
DMRT1	doublesex and mab-3 related transcription factor 1	0.062
CUL7	cullin 7	0.062
NRTN	neurturin	0.062
PRDM12	PR domain containing 12	0.062
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.062
DHH	desert hedgehog	0.062
EFNA2	ephrin-A2	0.062
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.062
MYT1	myelin transcription factor 1	0.061
PTF1A	pancreas specific transcription factor, 1a	0.061
NPAS4	neuronal PAS domain protein 4	0.061
GDF6	growth differentiation factor 6	0.061
GOLT1B	golgi transport 1B	0.061
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.061
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.061
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.061
CDV3	CDV3 homolog (mouse)	0.061
RET	ret proto-oncogene	0.061
RAP1A	RAP1A, member of RAS oncogene family	0.060
AQP5	aquaporin 5	0.060
TBX3	T-box 3	0.060
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.060
CAB39	calcium binding protein 39	0.060
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.060
HOXB8	homeobox B8	0.060
HOXD11	homeobox D11	0.060
PLCE1	phospholipase C, epsilon 1	0.060
NR2E1	nuclear receptor subfamily 2, group E, member 1	0.060
EN1	engrailed homeobox 1	0.059	Fly
NELL1	NEL-like 1 (chicken)	0.059
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.059
POMC	proopiomelanocortin	0.059
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.059
RNF8	ring finger protein 8	0.059
SOX17	SRY (sex determining region Y)-box 17	0.059
KLC2	kinesin light chain 2	0.059
E2F3	E2F transcription factor 3	0.058
TLX3	T-cell leukemia homeobox 3	0.058
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.058
HMGA2	high mobility group AT-hook 2	0.058
OXSR1	oxidative-stress responsive 1	0.058
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.058
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.058
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.058
IRX1	iroquois homeobox 1	0.058
PCDH17	protocadherin 17	0.058
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.057
TRIM9	tripartite motif containing 9	0.057
CSNK1G3	casein kinase 1, gamma 3	0.057
PLEC	plectin	0.057	Fly
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.057
GRIK3	glutamate receptor, ionotropic, kainate 3	0.056
MTA3	metastasis associated 1 family, member 3	0.056
GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	0.056
RHO	rhodopsin	0.056
FAM110A	family with sequence similarity 110, member A	0.056
HMX2	H6 family homeobox 2	0.056
POU2F3	POU class 2 homeobox 3	0.056	Human
FAM82A2	family with sequence similarity 82, member A2	0.056
F11R	F11 receptor	0.056
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.055
KLF5	Kruppel-like factor 5 (intestinal)	0.055
ZHX2	zinc fingers and homeoboxes 2	0.055
LMO1	LIM domain only 1 (rhombotin 1)	0.055
WNT3A	wingless-type MMTV integration site family, member 3A	0.055
SKP1	S-phase kinase-associated protein 1	0.055
ITGA6	integrin, alpha 6	0.055
CLDN5	claudin 5	0.055
EXOC1	exocyst complex component 1	0.055
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.055
AMN	amnionless homolog (mouse)	0.055
LAT	linker for activation of T cells	0.055
HOXB9	homeobox B9	0.055
TOX4	TOX high mobility group box family member 4	0.054
SUMF2	sulfatase modifying factor 2	0.054
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.054
COL13A1	collagen, type XIII, alpha 1	0.054
PRC1	protein regulator of cytokinesis 1	0.054
RUNX1	runt-related transcription factor 1	0.054
GRIP1	glutamate receptor interacting protein 1	0.054
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.054
IL11	interleukin 11	0.054
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.054
HNF1B	HNF1 homeobox B	0.054
SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	0.054
ZFPM1	zinc finger protein, multitype 1	0.053
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.053
CBFB	core-binding factor, beta subunit	0.053
CARM1	coactivator-associated arginine methyltransferase 1	0.053
LEF1	lymphoid enhancer-binding factor 1	0.053	Worm
CRABP1	cellular retinoic acid binding protein 1	0.053
NOL4	nucleolar protein 4	0.053
NPAS1	neuronal PAS domain protein 1	0.053
DCAF7	DDB1 and CUL4 associated factor 7	0.053
RAI2	retinoic acid induced 2	0.053
HEMGN	hemogen	0.053
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.053
S1PR1	sphingosine-1-phosphate receptor 1	0.053
CHD8	chromodomain helicase DNA binding protein 8	0.052
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.052
LHX6	LIM homeobox 6	0.052	Human
PHOX2A	paired-like homeobox 2a	0.052
SHOX2	short stature homeobox 2	0.052
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.052
DLL4	delta-like 4 (Drosophila)	0.052
DPYSL2	dihydropyrimidinase-like 2	0.052
TTYH1	tweety homolog 1 (Drosophila)	0.052
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.052
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.052
FEZF2	FEZ family zinc finger 2	0.052
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.052
SPTLC1	serine palmitoyltransferase, long chain base subunit 1	0.052
SORBS3	sorbin and SH3 domain containing 3	0.052
KIF18A	kinesin family member 18A	0.052
KATNA1	katanin p60 (ATPase containing) subunit A 1	0.052
ZAR1	zygote arrest 1	0.052
FOXL2	forkhead box L2	0.051
HES3	hairy and enhancer of split 3 (Drosophila)	0.051	Fly
HOXC4	homeobox C4	0.051
TBX21	T-box 21	0.051
ELL	elongation factor RNA polymerase II	0.051
RAP1B	RAP1B, member of RAS oncogene family	0.051
KIAA1549	KIAA1549	0.051
PTCH1	patched 1	0.051
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.051
CNOT3	CCR4-NOT transcription complex, subunit 3	0.051
CASP8AP2	caspase 8 associated protein 2	0.051
C19orf26	chromosome 19 open reading frame 26	0.051
BTBD3	BTB (POZ) domain containing 3	0.050
ITK	IL2-inducible T-cell kinase	0.050
GDF7	growth differentiation factor 7	0.050
ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	0.050
BAD	BCL2-associated agonist of cell death	0.050
OLIG1	oligodendrocyte transcription factor 1	0.050
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.050
CENPI	centromere protein I	0.050
SLC32A1	solute carrier family 32 (GABA vesicular transporter), member 1	0.050
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.050
PHTF2	putative homeodomain transcription factor 2	0.050
GATA2	GATA binding protein 2	0.050	Mouse
MCC	mutated in colorectal cancers	0.050
FOXD1	forkhead box D1	0.050
RCHY1	ring finger and CHY zinc finger domain containing 1	0.050
MYH10	myosin, heavy chain 10, non-muscle	0.050
ZEB2	zinc finger E-box binding homeobox 2	0.050
ISL2	ISL LIM homeobox 2	0.049	Human Fly
ZEB1	zinc finger E-box binding homeobox 1	0.049
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.049
BRD2	bromodomain containing 2	0.049
GHSR	growth hormone secretagogue receptor	0.049
SHH	sonic hedgehog	0.049
WNT7A	wingless-type MMTV integration site family, member 7A	0.049
LBR	lamin B receptor	0.049
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.049
APC2	adenomatosis polyposis coli 2	0.049
DBN1	drebrin 1	0.049
SOS2	son of sevenless homolog 2 (Drosophila)	0.049
GATAD2A	GATA zinc finger domain containing 2A	0.049
GSC	goosecoid homeobox	0.049
PBK	PDZ binding kinase	0.049
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.049
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.048
PRKCB	protein kinase C, beta	0.048
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.048
HIST1H3B	histone cluster 1, H3b	0.048
RFWD2	ring finger and WD repeat domain 2	0.048
ATAD2	ATPase family, AAA domain containing 2	0.048
AKT1S1	AKT1 substrate 1 (proline-rich)	0.048
PAX1	paired box 1	0.048
TTK	TTK protein kinase	0.048
BAHD1	bromo adjacent homology domain containing 1	0.048
NHLH1	nescient helix loop helix 1	0.048
BCL7A	B-cell CLL/lymphoma 7A	0.048
GATA6	GATA binding protein 6	0.048	Mouse
RAI14	retinoic acid induced 14	0.047
MELK	maternal embryonic leucine zipper kinase	0.047
SGOL1	shugoshin-like 1 (S. pombe)	0.047
EFNA1	ephrin-A1	0.047
SLIT2	slit homolog 2 (Drosophila)	0.047
SS18	synovial sarcoma translocation, chromosome 18	0.047
IRX5	iroquois homeobox 5	0.047
ING1	inhibitor of growth family, member 1	0.047
ANKRD11	ankyrin repeat domain 11	0.047
NXPH2	neurexophilin 2	0.047
ZC3H10	zinc finger CCCH-type containing 10	0.047
CELF4	CUGBP, Elav-like family member 4	0.047
ANLN	anillin, actin binding protein	0.047
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.047
BARHL1	BarH-like homeobox 1	0.047
ZFYVE9	zinc finger, FYVE domain containing 9	0.047	Fly
CADM1	cell adhesion molecule 1	0.047
FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.047
TMEM151B	transmembrane protein 151B	0.047
NCAM1	neural cell adhesion molecule 1	0.046
CNKSR1	connector enhancer of kinase suppressor of Ras 1	0.046
GAS1	growth arrest-specific 1	0.046
RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	0.046
TMEM47	transmembrane protein 47	0.046
BRSK2	BR serine/threonine kinase 2	0.046
UTRN	utrophin	0.046
VWF	von Willebrand factor	0.046
OTOP1	otopetrin 1	0.046
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.046
DMBX1	diencephalon/mesencephalon homeobox 1	0.046
HOXD9	homeobox D9	0.046
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.046
HAND1	heart and neural crest derivatives expressed 1	0.046
EPHB1	EPH receptor B1	0.046
GALR1	galanin receptor 1	0.046
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.046
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.046
EGLN1	egl nine homolog 1 (C. elegans)	0.046
TWIST1	twist homolog 1 (Drosophila)	0.045
EMX2	empty spiracles homeobox 2	0.045
NTN1	netrin 1	0.045
EYA1	eyes absent homolog 1 (Drosophila)	0.045
SNX33	sorting nexin 33	0.045
FGF18	fibroblast growth factor 18	0.045
NKD1	naked cuticle homolog 1 (Drosophila)	0.045
FLNA	filamin A, alpha	0.045
TRIO	triple functional domain (PTPRF interacting)	0.045
EDNRA	endothelin receptor type A	0.045
MPL	myeloproliferative leukemia virus oncogene	0.045
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.045
KLHL35	kelch-like 35 (Drosophila)	0.045
HOXC5	homeobox C5	0.045