IMP: Integrative Multi-species Prediction

Homo sapiens

38 genes annotated in human

epithelial tube morphogenesis

The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "epithelial tube morphogenesis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "epithelial tube morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.997
FGFR2	fibroblast growth factor receptor 2	0.993	Mouse Fly
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.957
ESR1	estrogen receptor 1	0.956	Mouse
SMN1	survival of motor neuron 1, telomeric	0.944
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.932	Zebrafish
NOTCH1	notch 1	0.923	Mouse Fly
VEGFA	vascular endothelial growth factor A	0.893	Mouse Fly
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.870
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.857
CREBBP	CREB binding protein	0.843
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.825	Mouse
SMAD3	SMAD family member 3	0.819	Mouse
JAG1	jagged 1	0.805
BMPR1A	bone morphogenetic protein receptor, type IA	0.783	Human Zebrafish
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.739	Human Mouse
APC	adenomatous polyposis coli	0.734
SQSTM1	sequestosome 1	0.725
NRP1	neuropilin 1	0.713	Mouse
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.674
XIAP	X-linked inhibitor of apoptosis	0.672
WNK4	WNK lysine deficient protein kinase 4	0.662
NCOR2	nuclear receptor corepressor 2	0.618
TSC2	tuberous sclerosis 2	0.613	Mouse
IQGAP1	IQ motif containing GTPase activating protein 1	0.589
TRIP6	thyroid hormone receptor interactor 6	0.577
TP53	tumor protein p53	0.559
BMP7	bone morphogenetic protein 7	0.542	Human Zebrafish Mouse
RXRA	retinoid X receptor, alpha	0.539
BMP2	bone morphogenetic protein 2	0.525	Human Mouse Fly
COL4A1	collagen, type IV, alpha 1	0.518
FGF1	fibroblast growth factor 1 (acidic)	0.512
NOTCH3	notch 3	0.504	Fly
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.503	Human Mouse
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.497
GATA4	GATA binding protein 4	0.485	Zebrafish Mouse
FBXW11	F-box and WD repeat domain containing 11	0.482
CUL3	cullin 3	0.481
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.429
EPAS1	endothelial PAS domain protein 1	0.422
MEIS1	Meis homeobox 1	0.412	Zebrafish
FKBP1A	FK506 binding protein 1A, 12kDa	0.400
HOXB5	homeobox B5	0.393
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.382
TIMP3	TIMP metallopeptidase inhibitor 3	0.380
DSP	desmoplakin	0.375
STK4	serine/threonine kinase 4	0.373	Mouse
PTK2	PTK2 protein tyrosine kinase 2	0.370
HIC1	hypermethylated in cancer 1	0.368
TBX5	T-box 5	0.343	Zebrafish
GSK3B	glycogen synthase kinase 3 beta	0.342
HOXA10	homeobox A10	0.340
EP300	E1A binding protein p300	0.340
CTNND1	catenin (cadherin-associated protein), delta 1	0.329
COL4A2	collagen, type IV, alpha 2	0.328	Human
FGF8	fibroblast growth factor 8 (androgen-induced)	0.327
EGFR	epidermal growth factor receptor	0.318	Fly
CAB39	calcium binding protein 39	0.312
ERBB2IP	erbb2 interacting protein	0.311	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.287	Human Zebrafish
COL2A1	collagen, type II, alpha 1	0.284
MEOX2	mesenchyme homeobox 2	0.284
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.281
SEC23A	Sec23 homolog A (S. cerevisiae)	0.270
ACTB	actin, beta	0.270
YAP1	Yes-associated protein 1	0.264	Mouse
FGF10	fibroblast growth factor 10	0.262
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.262
PBX1	pre-B-cell leukemia homeobox 1	0.252	Mouse
LRRK2	leucine-rich repeat kinase 2	0.247
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.233
FZD1	frizzled homolog 1 (Drosophila)	0.224	Mouse
FOXF1	forkhead box F1	0.216
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.216
SFRP1	secreted frizzled-related protein 1	0.209	Mouse
WNT3A	wingless-type MMTV integration site family, member 3A	0.203	Mouse
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.198
SMAD2	SMAD family member 2	0.198
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.193
FOXF2	forkhead box F2	0.184	Human
RARA	retinoic acid receptor, alpha	0.184	Mouse
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.180	Mouse
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.177
SORBS3	sorbin and SH3 domain containing 3	0.176
PRKCZ	protein kinase C, zeta	0.176
WT1	Wilms tumor 1	0.173
FSTL1	follistatin-like 1	0.164
FGFR1	fibroblast growth factor receptor 1	0.163	Fly
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.162
HOXA9	homeobox A9	0.162
FGF3	fibroblast growth factor 3	0.160	Human
TGFBR1	transforming growth factor, beta receptor 1	0.155	Human
TGFB3	transforming growth factor, beta 3	0.154
POU3F2	POU class 3 homeobox 2	0.153
TM4SF1	transmembrane 4 L six family member 1	0.152
HOXA11	homeobox A11	0.150	Mouse
BCL6	B-cell CLL/lymphoma 6	0.150
JAG2	jagged 2	0.142
MSX1	msh homeobox 1	0.142
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.141
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.141
EGR1	early growth response 1	0.140	Human
MYOD1	myogenic differentiation 1	0.138
BMPR1B	bone morphogenetic protein receptor, type IB	0.135	Human
BCOR	BCL6 corepressor	0.135
LIMK1	LIM domain kinase 1	0.135
PFN1	profilin 1	0.134	Mouse
SPRY4	sprouty homolog 4 (Drosophila)	0.134	Fly
TRRAP	transformation/transcription domain-associated protein	0.133
HIPK2	homeodomain interacting protein kinase 2	0.132
EGR3	early growth response 3	0.132	Human
COL4A6	collagen, type IV, alpha 6	0.132	Human Fly
MEIS2	Meis homeobox 2	0.131
PAX8	paired box 8	0.131
ENG	endoglin	0.131	Mouse
PAX2	paired box 2	0.130
CD44	CD44 molecule (Indian blood group)	0.126	Mouse
FGF4	fibroblast growth factor 4	0.123	Human
BBS1	Bardet-Biedl syndrome 1	0.121
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.120
FAS	Fas (TNF receptor superfamily, member 6)	0.119
MSN	moesin	0.117	Zebrafish
GAS6	growth arrest-specific 6	0.117
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.116	Human
UTRN	utrophin	0.116
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.115
PTCH1	patched 1	0.115
SETD8	SET domain containing (lysine methyltransferase) 8	0.115
COL4A5	collagen, type IV, alpha 5	0.114	Human Fly
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.114
AKAP11	A kinase (PRKA) anchor protein 11	0.113
GATA2	GATA binding protein 2	0.111
AXIN1	axin 1	0.109
BMP4	bone morphogenetic protein 4	0.109
BCAR1	breast cancer anti-estrogen resistance 1	0.108
TOP1	topoisomerase (DNA) I	0.107
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.105
GLI1	GLI family zinc finger 1	0.104
PCM1	pericentriolar material 1	0.104
FGF18	fibroblast growth factor 18	0.104
SMAD1	SMAD family member 1	0.100	Fly
HOXD13	homeobox D13	0.100
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.099
TGFB1	transforming growth factor, beta 1	0.098	Mouse Rat
KLHL3	kelch-like 3 (Drosophila)	0.098
WASL	Wiskott-Aldrich syndrome-like	0.096
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.096
PUM1	pumilio homolog 1 (Drosophila)	0.096
BBS2	Bardet-Biedl syndrome 2	0.095
DMD	dystrophin	0.093
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.093	Human Mouse
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.091
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.091	Fly
RET	ret proto-oncogene	0.089	Mouse
EFNA1	ephrin-A1	0.089
FZD7	frizzled homolog 7 (Drosophila)	0.089
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.088
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.088
ACVR1	activin A receptor, type I	0.088
POU5F1	POU class 5 homeobox 1	0.086
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.086	Zebrafish
SOX1	SRY (sex determining region Y)-box 1	0.085
FOXA2	forkhead box A2	0.085	Mouse Fly
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.084
PKP4	plakophilin 4	0.084
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.084
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.082	Fly
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.082
ADAM17	ADAM metallopeptidase domain 17	0.081
BMP1	bone morphogenetic protein 1	0.080
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.079
PML	promyelocytic leukemia	0.078	Mouse
FZD8	frizzled homolog 8 (Drosophila)	0.078
GDF5	growth differentiation factor 5	0.077	Human
LIN28B	lin-28 homolog B (C. elegans)	0.076
FOXC1	forkhead box C1	0.075
WNT1	wingless-type MMTV integration site family, member 1	0.075	Human Mouse Fly
CSNK1E	casein kinase 1, epsilon	0.075
NKX2-1	NK2 homeobox 1	0.074
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.074	Mouse
SFN	stratifin	0.073
SIM2	single-minded homolog 2 (Drosophila)	0.073
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.072
TGFB2	transforming growth factor, beta 2	0.072
C9orf89	chromosome 9 open reading frame 89	0.071
ACTN1	actinin, alpha 1	0.071
WNT5A	wingless-type MMTV integration site family, member 5A	0.070	Mouse
SMAD9	SMAD family member 9	0.070
CTNNBIP1	catenin, beta interacting protein 1	0.070
CDH5	cadherin 5, type 2 (vascular endothelium)	0.070
HOXB6	homeobox B6	0.070
SIX2	SIX homeobox 2	0.070	Mouse
TSC22D4	TSC22 domain family, member 4	0.070
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.069	Mouse Fly
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.068
ARNT	aryl hydrocarbon receptor nuclear translocator	0.067
INHBB	inhibin, beta B	0.066
GABARAP	GABA(A) receptor-associated protein	0.066
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.066
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.065
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.065
WNT6	wingless-type MMTV integration site family, member 6	0.065	Human
SP1	Sp1 transcription factor	0.064
DAPK1	death-associated protein kinase 1	0.064
HMGA2	high mobility group AT-hook 2	0.063
WNT2	wingless-type MMTV integration site family member 2	0.063	Human
DLL1	delta-like 1 (Drosophila)	0.062	Mouse
MAPK8	mitogen-activated protein kinase 8	0.061
EFNB3	ephrin-B3	0.060
NFIB	nuclear factor I/B	0.060
LUM	lumican	0.060
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.059	Fly
DCC	deleted in colorectal carcinoma	0.059
MEOX1	mesenchyme homeobox 1	0.059
TAOK1	TAO kinase 1	0.058
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.058
ALX4	ALX homeobox 4	0.057
GLI2	GLI family zinc finger 2	0.056	Mouse
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.056
GLI3	GLI family zinc finger 3	0.056	Mouse
MARK3	MAP/microtubule affinity-regulating kinase 3	0.055
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.055
NKX3-2	NK3 homeobox 2	0.054	Human
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.054	Mouse
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.054	Mouse
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.053
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.053
RUNX1	runt-related transcription factor 1	0.052
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.052
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.052
HOXD9	homeobox D9	0.051
TP73	tumor protein p73	0.051
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.051	Fly
SMAD7	SMAD family member 7	0.051	Fly
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.051
HOXD11	homeobox D11	0.051	Mouse
NCOA6	nuclear receptor coactivator 6	0.050
HR	hairless homolog (mouse)	0.049
DLX4	distal-less homeobox 4	0.049
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.049
EFNB2	ephrin-B2	0.049
WNT11	wingless-type MMTV integration site family, member 11	0.048
TBX2	T-box 2	0.048
CHRD	chordin	0.048	Zebrafish
HOXC8	homeobox C8	0.048
DUSP6	dual specificity phosphatase 6	0.048	Fly
WNT4	wingless-type MMTV integration site family, member 4	0.047	Human
RB1	retinoblastoma 1	0.047
BCL3	B-cell CLL/lymphoma 3	0.047
MNX1	motor neuron and pancreas homeobox 1	0.047
COL5A1	collagen, type V, alpha 1	0.046
NGFR	nerve growth factor receptor	0.046
HOXD1	homeobox D1	0.046
HOXB13	homeobox B13	0.046
BCL2L1	BCL2-like 1	0.046
NCOA1	nuclear receptor coactivator 1	0.045
TJP1	tight junction protein 1 (zona occludens 1)	0.045	Fly
FZD10	frizzled homolog 10 (Drosophila)	0.045
HOXC11	homeobox C11	0.045
PAX6	paired box 6	0.044
CXCL12	chemokine (C-X-C motif) ligand 12	0.044	Mouse
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.044
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.044
OTX2	orthodenticle homeobox 2	0.044
PRRX2	paired related homeobox 2	0.043
BTBD10	BTB (POZ) domain containing 10	0.043
S100A4	S100 calcium binding protein A4	0.043
PRRX1	paired related homeobox 1	0.043
ESR2	estrogen receptor 2 (ER beta)	0.043
GDF6	growth differentiation factor 6	0.043
HOXB9	homeobox B9	0.043
PBK	PDZ binding kinase	0.042
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.042
COL7A1	collagen, type VII, alpha 1	0.042
MAML1	mastermind-like 1 (Drosophila)	0.042
EGR2	early growth response 2	0.042	Human
FGF7	fibroblast growth factor 7	0.041	Human
MARCKSL1	MARCKS-like 1	0.041
MED25	mediator complex subunit 25	0.041
ACAN	aggrecan	0.040
WISP1	WNT1 inducible signaling pathway protein 1	0.040
INHBA	inhibin, beta A	0.040
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.040
CHD4	chromodomain helicase DNA binding protein 4	0.040
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.040	Fly
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.040	Fly
COL13A1	collagen, type XIII, alpha 1	0.040
TWSG1	twisted gastrulation homolog 1 (Drosophila)	0.039
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.039	Mouse Fly
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.039
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.039
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.039
CALCA	calcitonin-related polypeptide alpha	0.039
SOX11	SRY (sex determining region Y)-box 11	0.039	Mouse
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.039	Fly
AR	androgen receptor	0.038	Mouse
DAXX	death-domain associated protein	0.038
NOG	noggin	0.038	Mouse
COL1A2	collagen, type I, alpha 2	0.038
HOXA4	homeobox A4	0.038
LAPTM5	lysosomal protein transmembrane 5	0.038
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.038
PITX3	paired-like homeodomain 3	0.038
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.038
WNT10A	wingless-type MMTV integration site family, member 10A	0.038	Human
HOXA5	homeobox A5	0.037	Mouse
LRP6	low density lipoprotein receptor-related protein 6	0.037	Mouse
ONECUT1	one cut homeobox 1	0.037
HMX1	H6 family homeobox 1	0.037
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.037
CEP164	centrosomal protein 164kDa	0.036
COL3A1	collagen, type III, alpha 1	0.036
SGMS1	sphingomyelin synthase 1	0.036
CSNK1D	casein kinase 1, delta	0.036
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.036
RAX	retina and anterior neural fold homeobox	0.036
HMOX2	heme oxygenase (decycling) 2	0.036
ITSN1	intersectin 1 (SH3 domain protein)	0.036
GDNF	glial cell derived neurotrophic factor	0.036
GRB2	growth factor receptor-bound protein 2	0.035
CFLAR	CASP8 and FADD-like apoptosis regulator	0.035
PRKG1	protein kinase, cGMP-dependent, type I	0.035
KIAA1377	KIAA1377	0.035
SNX5	sorting nexin 5	0.035
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.035
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.035
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.035
STC1	stanniocalcin 1	0.035
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.035
FHL1	four and a half LIM domains 1	0.035
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.035	Human
EN2	engrailed homeobox 2	0.034
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.034
ANKRD28	ankyrin repeat domain 28	0.034
HOXD10	homeobox D10	0.034
FOXL1	forkhead box L1	0.034
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.034
DIO3	deiodinase, iodothyronine, type III	0.034
NKD2	naked cuticle homolog 2 (Drosophila)	0.034
MYST2	MYST histone acetyltransferase 2	0.034
COL1A1	collagen, type I, alpha 1	0.034
CLDN4	claudin 4	0.033
FADD	Fas (TNFRSF6)-associated via death domain	0.033
PLXNB1	plexin B1	0.033
TERT	telomerase reverse transcriptase	0.033
GAS1	growth arrest-specific 1	0.033
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.033
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.032
HOXA7	homeobox A7	0.032
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.032
PJA1	praja ring finger 1	0.032
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.032
SPOP	speckle-type POZ protein	0.032
MKL1	megakaryoblastic leukemia (translocation) 1	0.032
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.032	Fly
CCNK	cyclin K	0.032
FZD4	frizzled homolog 4 (Drosophila)	0.032
FOXA1	forkhead box A1	0.032	Mouse Fly
COL11A1	collagen, type XI, alpha 1	0.031
USP9X	ubiquitin specific peptidase 9, X-linked	0.031
NKX3-1	NK3 homeobox 1	0.031	Mouse
RYK	RYK receptor-like tyrosine kinase	0.031	Human
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.031
HES2	hairy and enhancer of split 2 (Drosophila)	0.031
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.031
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.031
GATA5	GATA binding protein 5	0.031
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.031	Mouse
FOXB1	forkhead box B1	0.031
BBS7	Bardet-Biedl syndrome 7	0.031
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.031	Mouse
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.031
GATA6	GATA binding protein 6	0.030
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.030
IRX4	iroquois homeobox 4	0.030
SIRT1	sirtuin 1	0.030
HNF1B	HNF1 homeobox B	0.030	Mouse
MYOCD	myocardin	0.030
FOXD3	forkhead box D3	0.029
POSTN	periostin, osteoblast specific factor	0.029
YY1	YY1 transcription factor	0.029
LDB1	LIM domain binding 1	0.029
SASS6	spindle assembly 6 homolog (C. elegans)	0.029
SOX17	SRY (sex determining region Y)-box 17	0.029	Mouse
IHH	Indian hedgehog	0.029
TP53BP2	tumor protein p53 binding protein, 2	0.029
HNF1A	HNF1 homeobox A	0.029
FGFR3	fibroblast growth factor receptor 3	0.029	Fly
SIX6	SIX homeobox 6	0.029
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.029	Zebrafish Mouse
RBBP8	retinoblastoma binding protein 8	0.029
CAV1	caveolin 1, caveolae protein, 22kDa	0.029
PARVA	parvin, alpha	0.028
MYH9	myosin, heavy chain 9, non-muscle	0.028	Fly
LMAN1	lectin, mannose-binding, 1	0.028
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.028
OAF	OAF homolog (Drosophila)	0.028
MAX	MYC associated factor X	0.028
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.028
SMO	smoothened homolog (Drosophila)	0.028	Zebrafish
IRX5	iroquois homeobox 5	0.028
ZYX	zyxin	0.028
NID1	nidogen 1	0.028
ATXN7	ataxin 7	0.027
JDP2	Jun dimerization protein 2	0.027
VEGFC	vascular endothelial growth factor C	0.027
BBS10	Bardet-Biedl syndrome 10	0.027
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.027
VASP	vasodilator-stimulated phosphoprotein	0.027	Mouse
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.027
DSG2	desmoglein 2	0.027
EGLN1	egl nine homolog 1 (C. elegans)	0.027
CAPRIN2	caprin family member 2	0.026
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.026
SOX18	SRY (sex determining region Y)-box 18	0.026
PHOX2A	paired-like homeobox 2a	0.026
SFRP2	secreted frizzled-related protein 2	0.026	Mouse
CDX2	caudal type homeobox 2	0.026
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.026
KAT2B	K(lysine) acetyltransferase 2B	0.026
THBS1	thrombospondin 1	0.026
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.026
TPM4	tropomyosin 4	0.026
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.026
PXDN	peroxidasin homolog (Drosophila)	0.026
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.026
OTP	orthopedia homeobox	0.026
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.026
HOXA13	homeobox A13	0.025
SALL2	sal-like 2 (Drosophila)	0.025
EYA2	eyes absent homolog 2 (Drosophila)	0.025
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.025
ECEL1	endothelin converting enzyme-like 1	0.025
TTC8	tetratricopeptide repeat domain 8	0.025
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.025
OCLN	occludin	0.025
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.025
SPDEF	SAM pointed domain containing ets transcription factor	0.025
STK36	serine/threonine kinase 36	0.025
QARS	glutaminyl-tRNA synthetase	0.025
COTL1	coactosin-like 1 (Dictyostelium)	0.025
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.025
ZNF746	zinc finger protein 746	0.025
LDB2	LIM domain binding 2	0.024
TBX1	T-box 1	0.024
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.024
IGF1R	insulin-like growth factor 1 receptor	0.024
HOXC5	homeobox C5	0.024
SPRY2	sprouty homolog 2 (Drosophila)	0.024	Mouse Fly
SIX3	SIX homeobox 3	0.024
WNT7A	wingless-type MMTV integration site family, member 7A	0.024	Human
FAM46A	family with sequence similarity 46, member A	0.024
HOXB3	homeobox B3	0.024
MCC	mutated in colorectal cancers	0.024
KRT18	keratin 18	0.024
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.024	Mouse
HMGXB4	HMG box domain containing 4	0.024
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.024
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.024
SOX9	SRY (sex determining region Y)-box 9	0.024	Mouse
SYK	spleen tyrosine kinase	0.024
DST	dystonin	0.024	Fly
TLX1	T-cell leukemia homeobox 1	0.024
NEUROG2	neurogenin 2	0.024
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.023
HOXB8	homeobox B8	0.023
SMAD4	SMAD family member 4	0.023	Mouse
DPY19L4	dpy-19-like 4 (C. elegans)	0.023
RBPMS	RNA binding protein with multiple splicing	0.023
TWIST1	twist homolog 1 (Drosophila)	0.023	Mouse Fly
VAX2	ventral anterior homeobox 2	0.023
EIF3CL	eukaryotic translation initiation factor 3, subunit C-like	0.023
NKX6-1	NK6 homeobox 1	0.023
COL6A1	collagen, type VI, alpha 1	0.023
EN1	engrailed homeobox 1	0.023
HAND1	heart and neural crest derivatives expressed 1	0.023	Mouse
GPR161	G protein-coupled receptor 161	0.023
MED24	mediator complex subunit 24	0.023
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.023
MKL2	MKL/myocardin-like 2	0.023
SORBS2	sorbin and SH3 domain containing 2	0.023
PDX1	pancreatic and duodenal homeobox 1	0.023
PAX7	paired box 7	0.023
PAX9	paired box 9	0.023	Human
S100A2	S100 calcium binding protein A2	0.023
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.023
BNC1	basonuclin 1	0.023
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.022
TNC	tenascin C	0.022
PCDH17	protocadherin 17	0.022
BBS9	Bardet-Biedl syndrome 9	0.022
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.022
TBX3	T-box 3	0.022	Mouse
TCF21	transcription factor 21	0.022	Mouse
MECOM	MDS1 and EVI1 complex locus	0.022
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.022
PDE10A	phosphodiesterase 10A	0.022
PDGFC	platelet derived growth factor C	0.022
PITX1	paired-like homeodomain 1	0.022
LMO4	LIM domain only 4	0.022	Mouse
CTBP2	C-terminal binding protein 2	0.022
NLK	nemo-like kinase	0.022
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.022
SRCIN1	SRC kinase signaling inhibitor 1	0.022
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.022
USP22	ubiquitin specific peptidase 22	0.022
CAPNS1	calpain, small subunit 1	0.022
WIF1	WNT inhibitory factor 1	0.022
SETD7	SET domain containing (lysine methyltransferase) 7	0.022
NUP153	nucleoporin 153kDa	0.022
PTHLH	parathyroid hormone-like hormone	0.022
CADM4	cell adhesion molecule 4	0.022
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.022
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.022
E2F3	E2F transcription factor 3	0.022
BCAP31	B-cell receptor-associated protein 31	0.022
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.022	Human Zebrafish Mouse
SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2	0.022	Mouse
PSEN1	presenilin 1	0.021	Mouse
TCF4	transcription factor 4	0.021
TADA2A	transcriptional adaptor 2A	0.021
TAGLN2	transgelin 2	0.021
MAGED2	melanoma antigen family D, 2	0.021
EPHB2	EPH receptor B2	0.021
SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	0.021	Mouse Fly
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.021
RUNX2	runt-related transcription factor 2	0.021
FGFR1OP2	FGFR1 oncogene partner 2	0.021
ACVR1B	activin A receptor, type IB	0.021	Human
ARHGAP5	Rho GTPase activating protein 5	0.021
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.021
TWIST2	twist homolog 2 (Drosophila)	0.021
FGD1	FYVE, RhoGEF and PH domain containing 1	0.021
DLG5	discs, large homolog 5 (Drosophila)	0.021	Mouse
BHLHE23	basic helix-loop-helix family, member e23	0.021
HOXC13	homeobox C13	0.021
RNF144B	ring finger protein 144B	0.021
FNDC3B	fibronectin type III domain containing 3B	0.021
WNK1	WNK lysine deficient protein kinase 1	0.021	Human
MDFI	MyoD family inhibitor	0.021
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.020
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.020
HAS2	hyaluronan synthase 2	0.020	Zebrafish
EXOC5	exocyst complex component 5	0.020
EYA1	eyes absent homolog 1 (Drosophila)	0.020
HOXC6	homeobox C6	0.020
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.020
LAMA5	laminin, alpha 5	0.020	Mouse
AMOTL1	angiomotin like 1	0.020
FZD6	frizzled homolog 6 (Drosophila)	0.020	Mouse
LHX9	LIM homeobox 9	0.020
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.020
NAGK	N-acetylglucosamine kinase	0.020
NUMBL	numb homolog (Drosophila)-like	0.020
PGF	placental growth factor	0.020	Mouse
FOXG1	forkhead box G1	0.020
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.020
WDYHV1	WDYHV motif containing 1	0.020
HAND2	heart and neural crest derivatives expressed 2	0.020	Zebrafish Mouse
DLL3	delta-like 3 (Drosophila)	0.020
CDK4	cyclin-dependent kinase 4	0.020
FEV	FEV (ETS oncogene family)	0.020
SIX5	SIX homeobox 5	0.020
BIRC2	baculoviral IAP repeat containing 2	0.020
PBRM1	polybromo 1	0.020
BMP8A	bone morphogenetic protein 8a	0.019	Human
HOXD3	homeobox D3	0.019
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.019
LHX5	LIM homeobox 5	0.019
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.019
TIMP2	TIMP metallopeptidase inhibitor 2	0.019
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.019	Mouse
PTF1A	pancreas specific transcription factor, 1a	0.019
ALX3	ALX homeobox 3	0.019
CRLF1	cytokine receptor-like factor 1	0.019
CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	0.019
COL5A2	collagen, type V, alpha 2	0.019
THBS2	thrombospondin 2	0.019
AKIP1	A kinase (PRKA) interacting protein 1	0.019
GDF10	growth differentiation factor 10	0.019	Human
UNC5A	unc-5 homolog A (C. elegans)	0.019
HMX3	H6 family homeobox 3	0.019
SMAD6	SMAD family member 6	0.019	Fly
PKN2	protein kinase N2	0.019
LBX1	ladybird homeobox 1	0.019	Mouse
EPHB3	EPH receptor B3	0.019
SLIT3	slit homolog 3 (Drosophila)	0.019	Human
NPAS1	neuronal PAS domain protein 1	0.019
NOTCH4	notch 4	0.018	Mouse Fly
SLIT2	slit homolog 2 (Drosophila)	0.018
GPR124	G protein-coupled receptor 124	0.018
CTTN	cortactin	0.018
CEP135	centrosomal protein 135kDa	0.018
WNT3	wingless-type MMTV integration site family, member 3	0.018	Human
ANGPTL2	angiopoietin-like 2	0.018
SEC24D	SEC24 family, member D (S. cerevisiae)	0.018
F2R	coagulation factor II (thrombin) receptor	0.018
FOXN4	forkhead box N4	0.018
GAB1	GRB2-associated binding protein 1	0.018
NOTCH2	notch 2	0.018	Mouse Fly
GSC	goosecoid homeobox	0.018
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.018
SFRP5	secreted frizzled-related protein 5	0.018	Mouse
ZMYND11	zinc finger, MYND-type containing 11	0.018
MBD2	methyl-CpG binding domain protein 2	0.018
ITGA8	integrin, alpha 8	0.018
CLDN7	claudin 7	0.018
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.018	Human
ITGB4	integrin, beta 4	0.018
FGF2	fibroblast growth factor 2 (basic)	0.018
OXA1L	oxidase (cytochrome c) assembly 1-like	0.018
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.018
SOCS5	suppressor of cytokine signaling 5	0.018
OLIG2	oligodendrocyte lineage transcription factor 2	0.018
ZEB2	zinc finger E-box binding homeobox 2	0.018	Mouse
TSC1	tuberous sclerosis 1	0.018	Mouse
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.017
NPPC	natriuretic peptide C	0.017
GJA3	gap junction protein, alpha 3, 46kDa	0.017
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.017
TNRC6B	trinucleotide repeat containing 6B	0.017
CD248	CD248 molecule, endosialin	0.017
RNR2	l-rRNA	0.017
PITX2	paired-like homeodomain 2	0.017	Mouse
PRDM12	PR domain containing 12	0.017
CCNO	cyclin O	0.017
SH3KBP1	SH3-domain kinase binding protein 1	0.017
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.017
PAX1	paired box 1	0.017	Human
JPH3	junctophilin 3	0.017
EDNRA	endothelin receptor type A	0.017	Mouse
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.017
HOXD8	homeobox D8	0.017
VAV2	vav 2 guanine nucleotide exchange factor	0.017
PLAT	plasminogen activator, tissue	0.017
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.017
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.017
RSPO1	R-spondin homolog (Xenopus laevis)	0.017
SAV1	salvador homolog 1 (Drosophila)	0.017
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.017
TRADD	TNFRSF1A-associated via death domain	0.017
SHOX2	short stature homeobox 2	0.017
LAMA1	laminin, alpha 1	0.017	Mouse
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.017
CDK11B	cyclin-dependent kinase 11B	0.017
GBX2	gastrulation brain homeobox 2	0.017	Mouse
PDE4DIP	phosphodiesterase 4D interacting protein	0.017
C1QL1	complement component 1, q subcomponent-like 1	0.017
RARG	retinoic acid receptor, gamma	0.017	Mouse
SOX21	SRY (sex determining region Y)-box 21	0.017
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.017
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.017
ARL6	ADP-ribosylation factor-like 6	0.017
FGF5	fibroblast growth factor 5	0.016	Human
QPRT	quinolinate phosphoribosyltransferase	0.016
CSF1	colony stimulating factor 1 (macrophage)	0.016	Mouse
SCARF2	scavenger receptor class F, member 2	0.016
DCLK1	doublecortin-like kinase 1	0.016
VCL	vinculin	0.016
DLX5	distal-less homeobox 5	0.016
KANK2	KN motif and ankyrin repeat domains 2	0.016
AKAP6	A kinase (PRKA) anchor protein 6	0.016
POU3F1	POU class 3 homeobox 1	0.016
HES1	hairy and enhancer of split 1, (Drosophila)	0.016	Mouse
TRIL	TLR4 interactor with leucine-rich repeats	0.016
FLT4	fms-related tyrosine kinase 4	0.016	Fly
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.016
FGF19	fibroblast growth factor 19	0.016
FOXE3	forkhead box E3	0.016
VCAN	versican	0.016
NXPH3	neurexophilin 3	0.016
GRIK3	glutamate receptor, ionotropic, kainate 3	0.016
VCAM1	vascular cell adhesion molecule 1	0.016
PTPRB	protein tyrosine phosphatase, receptor type, B	0.016
NCK2	NCK adaptor protein 2	0.016
LGALS8	lectin, galactoside-binding, soluble, 8	0.016
LHX1	LIM homeobox 1	0.016	Mouse
BAD	BCL2-associated agonist of cell death	0.016
PRMT6	protein arginine methyltransferase 6	0.016
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.016
ACVR2A	activin A receptor, type IIA	0.016
HOXA2	homeobox A2	0.016
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.016
COLEC12	collectin sub-family member 12	0.016
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.016	Mouse
MMP19	matrix metallopeptidase 19	0.016
COIL	coilin	0.016
EXOC7	exocyst complex component 7	0.016
LAMA4	laminin, alpha 4	0.015
ZNF148	zinc finger protein 148	0.015
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.015
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.015
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.015
NCSTN	nicastrin	0.015
CDK8	cyclin-dependent kinase 8	0.015
XIRP1	xin actin-binding repeat containing 1	0.015
FOXQ1	forkhead box Q1	0.015
TAL1	T-cell acute lymphocytic leukemia 1	0.015
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.015
RHOC	ras homolog gene family, member C	0.015	Fly
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.015
LAMC3	laminin, gamma 3	0.015
PRPH	peripherin	0.015
HMGA1	high mobility group AT-hook 1	0.015
NUMA1	nuclear mitotic apparatus protein 1	0.015
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.015
CALCR	calcitonin receptor	0.015
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.015
CRABP2	cellular retinoic acid binding protein 2	0.015
DEDD	death effector domain containing	0.015
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.015
BAK1	BCL2-antagonist/killer 1	0.015
ARID3C	AT rich interactive domain 3C (BRIGHT-like)	0.015
GRP	gastrin-releasing peptide	0.015
SOX2	SRY (sex determining region Y)-box 2	0.015	Mouse
EZR	ezrin	0.015
HSPA1B	heat shock 70kDa protein 1B	0.015
DPYSL2	dihydropyrimidinase-like 2	0.015
ACVRL1	activin A receptor type II-like 1	0.015
STK3	serine/threonine kinase 3	0.015	Mouse
COMP	cartilage oligomeric matrix protein	0.015
EMX1	empty spiracles homeobox 1	0.015
MMS19	MMS19 nucleotide excision repair homolog (S. cerevisiae)	0.015
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.015
TUBB2B	tubulin, beta 2B	0.015
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.015
SPAG9	sperm associated antigen 9	0.015
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.015
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.015
FIBCD1	fibrinogen C domain containing 1	0.015
CANX	calnexin	0.015
A4GALT	alpha 1,4-galactosyltransferase	0.014
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.014
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.014
HOXC10	homeobox C10	0.014
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.014
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.014
DHH	desert hedgehog	0.014
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.014
TNK2	tyrosine kinase, non-receptor, 2	0.014
WDFY3	WD repeat and FYVE domain containing 3	0.014
FHL2	four and a half LIM domains 2	0.014
FOXL2	forkhead box L2	0.014
NCOA2	nuclear receptor coactivator 2	0.014
RYR2	ryanodine receptor 2 (cardiac)	0.014	Mouse
COL14A1	collagen, type XIV, alpha 1	0.014
VSX1	visual system homeobox 1	0.014
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.014
EFNA2	ephrin-A2	0.014
PSG9	pregnancy specific beta-1-glycoprotein 9	0.014