IMP: Integrative Multi-species Prediction

Homo sapiens

31 genes annotated in human

cartilage development

The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cartilage development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cartilage development" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.997
FBN1	fibrillin 1	0.908
SMAD7	SMAD family member 7	0.904
PAX3	paired box 3	0.782
FN1	fibronectin 1	0.745
LOX	lysyl oxidase	0.705	Zebrafish
LTBP2	latent transforming growth factor beta binding protein 2	0.685	Human
COL1A1	collagen, type I, alpha 1	0.671	Human Mouse
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.653	Zebrafish
ELN	elastin	0.648
COL3A1	collagen, type III, alpha 1	0.638	Human
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.637
COL1A2	collagen, type I, alpha 2	0.583	Human
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.458
BMP2	bone morphogenetic protein 2	0.420
COL6A1	collagen, type VI, alpha 1	0.408
LUM	lumican	0.385	Rat
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.365
BMPR1A	bone morphogenetic protein receptor, type IA	0.362	Human Mouse
FSTL1	follistatin-like 1	0.347
SMAD3	SMAD family member 3	0.347	Mouse
COL5A2	collagen, type V, alpha 2	0.343	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.326
FGF1	fibroblast growth factor 1 (acidic)	0.326	Human
SMAD4	SMAD family member 4	0.325
COL6A2	collagen, type VI, alpha 2	0.324
CTGF	connective tissue growth factor	0.312	Mouse
NOTCH3	notch 3	0.309
TGFB1	transforming growth factor, beta 1	0.306
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.297	Human Mouse
COL5A1	collagen, type V, alpha 1	0.296	Human
FGFR1	fibroblast growth factor receptor 1	0.292	Mouse
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.233	Human
DCN	decorin	0.232	Zebrafish
MAPK1	mitogen-activated protein kinase 1	0.216
TNC	tenascin C	0.205
BMP7	bone morphogenetic protein 7	0.201
EP300	E1A binding protein p300	0.198
HOXD9	homeobox D9	0.198
THBS1	thrombospondin 1	0.192	Mouse
RB1	retinoblastoma 1	0.186
SEC31A	SEC31 homolog A (S. cerevisiae)	0.180
POSTN	periostin, osteoblast specific factor	0.174
COL2A1	collagen, type II, alpha 1	0.172	Human Mouse Rat
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.172
HIPK2	homeodomain interacting protein kinase 2	0.166
FGF2	fibroblast growth factor 2 (basic)	0.165
VCAN	versican	0.162
CALD1	caldesmon 1	0.160
MSX1	msh homeobox 1	0.156	Mouse Rat
DDR2	discoidin domain receptor tyrosine kinase 2	0.154
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.148
BMP1	bone morphogenetic protein 1	0.145
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.131
BBS10	Bardet-Biedl syndrome 10	0.128
FOXD3	forkhead box D3	0.127	Zebrafish
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.126
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.121
MSN	moesin	0.121
HOXA10	homeobox A10	0.120
BGN	biglycan	0.118
IGFBP5	insulin-like growth factor binding protein 5	0.115
BMI1	BMI1 polycomb ring finger oncogene	0.115
TWIST1	twist homolog 1 (Drosophila)	0.114
WNT1	wingless-type MMTV integration site family, member 1	0.113	Human
FZD1	frizzled homolog 1 (Drosophila)	0.113
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.112	Zebrafish
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.112
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.110
BMPR1B	bone morphogenetic protein receptor, type IB	0.110	Human Mouse
MFAP5	microfibrillar associated protein 5	0.108
PCOLCE	procollagen C-endopeptidase enhancer	0.107
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.106
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.105
RARA	retinoic acid receptor, alpha	0.101	Mouse
TGFBR1	transforming growth factor, beta receptor 1	0.097	Human Mouse
EDNRA	endothelin receptor type A	0.097	Zebrafish
LOXL1	lysyl oxidase-like 1	0.097
NRP1	neuropilin 1	0.092	Zebrafish
ACVR1	activin A receptor, type I	0.092	Human
TGFB3	transforming growth factor, beta 3	0.090	Zebrafish
GDF5	growth differentiation factor 5	0.090	Mouse
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.089
FAP	fibroblast activation protein, alpha	0.089
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.087
MXRA5	matrix-remodelling associated 5	0.083
TGFB2	transforming growth factor, beta 2	0.081	Human Mouse
PTCH1	patched 1	0.079
COL6A3	collagen, type VI, alpha 3	0.076
WNT3A	wingless-type MMTV integration site family, member 3A	0.074	Human
FBLN2	fibulin 2	0.073	Human
RUNX1	runt-related transcription factor 1	0.072
TP53	tumor protein p53	0.070
ACAN	aggrecan	0.069	Mouse Rat
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.069
HMGA2	high mobility group AT-hook 2	0.068
SULF1	sulfatase 1	0.068	Mouse
HDAC6	histone deacetylase 6	0.068
IGFBP3	insulin-like growth factor binding protein 3	0.068
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.067
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.065
ENG	endoglin	0.064
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.063
NCOR2	nuclear receptor corepressor 2	0.062
BMP4	bone morphogenetic protein 4	0.062
MFAP2	microfibrillar-associated protein 2	0.062
CHRD	chordin	0.060
NRP2	neuropilin 2	0.060
WISP1	WNT1 inducible signaling pathway protein 1	0.060
LTBP4	latent transforming growth factor beta binding protein 4	0.060	Human
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.058
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.057
ADAM12	ADAM metallopeptidase domain 12	0.055
POU3F2	POU class 3 homeobox 2	0.055
FKBP1A	FK506 binding protein 1A, 12kDa	0.055
INHBA	inhibin, beta A	0.054
FGF18	fibroblast growth factor 18	0.054
SDC2	syndecan 2	0.054
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.054
ITGB5	integrin, beta 5	0.053	Human
SOX2	SRY (sex determining region Y)-box 2	0.052	Human
FGF3	fibroblast growth factor 3	0.052	Human
SP1	Sp1 transcription factor	0.052
EGR1	early growth response 1	0.052
VEGFA	vascular endothelial growth factor A	0.051
SOX9	SRY (sex determining region Y)-box 9	0.050
HOXB5	homeobox B5	0.049
SFRP4	secreted frizzled-related protein 4	0.049
AMOTL2	angiomotin like 2	0.049
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.049
MYOD1	myogenic differentiation 1	0.048
VEGFC	vascular endothelial growth factor C	0.048
FGF8	fibroblast growth factor 8 (androgen-induced)	0.047
RBMS3	RNA binding motif, single stranded interacting protein 3	0.047
POU5F1	POU class 5 homeobox 1	0.047
PCGF2	polycomb group ring finger 2	0.046
NOTCH1	notch 1	0.046
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.046
FNDC1	fibronectin type III domain containing 1	0.046
EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	0.046
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.046
DLX4	distal-less homeobox 4	0.045
LTBP1	latent transforming growth factor beta binding protein 1	0.045	Human
PRRX1	paired related homeobox 1	0.045	Mouse
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.045
SEC24D	SEC24 family, member D (S. cerevisiae)	0.045
HSPG2	heparan sulfate proteoglycan 2	0.044	Mouse
RUNX2	runt-related transcription factor 2	0.044	Zebrafish Mouse
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.043
HAS2	hyaluronan synthase 2	0.042
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.042	Mouse
HDAC4	histone deacetylase 4	0.042
MSX2	msh homeobox 2	0.042	Mouse Rat
SMAD1	SMAD family member 1	0.041	Mouse
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.041
HOXB6	homeobox B6	0.041
PDZD11	PDZ domain containing 11	0.040
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.040
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.040
COL4A1	collagen, type IV, alpha 1	0.039
HMGA1	high mobility group AT-hook 1	0.039	Human
FZD8	frizzled homolog 8 (Drosophila)	0.039
WNT11	wingless-type MMTV integration site family, member 11	0.039	Human
WNT6	wingless-type MMTV integration site family, member 6	0.039	Human
AR	androgen receptor	0.039
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.038
SFRP1	secreted frizzled-related protein 1	0.038
TBX2	T-box 2	0.038
FBLN1	fibulin 1	0.038	Human
RXRA	retinoid X receptor, alpha	0.038
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.038
COL11A1	collagen, type XI, alpha 1	0.038	Mouse
OSMR	oncostatin M receptor	0.037
HOXA4	homeobox A4	0.037
PXDN	peroxidasin homolog (Drosophila)	0.036
PLEC	plectin	0.036
FBLN5	fibulin 5	0.036	Human
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.036
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.035
TP63	tumor protein p63	0.035
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.035
LAMB1	laminin, beta 1	0.035
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.034
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.034
HOXC8	homeobox C8	0.034
ATN1	atrophin 1	0.034
EPAS1	endothelial PAS domain protein 1	0.033
MRC2	mannose receptor, C type 2	0.032
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.032
DAXX	death-domain associated protein	0.031
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.031
MGP	matrix Gla protein	0.031
CRLF1	cytokine receptor-like factor 1	0.031
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.030
SH3BP4	SH3-domain binding protein 4	0.030
EED	embryonic ectoderm development	0.030
MYOCD	myocardin	0.030
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.030
ESR1	estrogen receptor 1	0.030
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.030
TIMP3	TIMP metallopeptidase inhibitor 3	0.029
STC1	stanniocalcin 1	0.029
CBX8	chromobox homolog 8	0.029
INHBB	inhibin, beta B	0.028
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.028	Human
MAX	MYC associated factor X	0.028
MKL1	megakaryoblastic leukemia (translocation) 1	0.028
COL14A1	collagen, type XIV, alpha 1	0.028
FERMT2	fermitin family member 2	0.028
TJP1	tight junction protein 1 (zona occludens 1)	0.028
HOXD13	homeobox D13	0.027
TGFBI	transforming growth factor, beta-induced, 68kDa	0.027
IGFBP7	insulin-like growth factor binding protein 7	0.027
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.027	Zebrafish
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.027
LBX1	ladybird homeobox 1	0.026
CAV2	caveolin 2	0.026
PRRX2	paired related homeobox 2	0.026	Mouse
COL13A1	collagen, type XIII, alpha 1	0.026
GDNF	glial cell derived neurotrophic factor	0.026
FURIN	furin (paired basic amino acid cleaving enzyme)	0.026	Zebrafish
LOXL2	lysyl oxidase-like 2	0.026	Mouse
HOXA7	homeobox A7	0.025
WWTR1	WW domain containing transcription regulator 1	0.025
PTHLH	parathyroid hormone-like hormone	0.025
CDK6	cyclin-dependent kinase 6	0.025
ANXA5	annexin A5	0.025
ALX4	ALX homeobox 4	0.025
TIMP1	TIMP metallopeptidase inhibitor 1	0.025	Rat
VSX1	visual system homeobox 1	0.025
GDF6	growth differentiation factor 6	0.025
ZMYND8	zinc finger, MYND-type containing 8	0.024
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.024
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.024
EDN1	endothelin 1	0.024	Mouse
GATA4	GATA binding protein 4	0.024
EFNB2	ephrin-B2	0.023
GJA1	gap junction protein, alpha 1, 43kDa	0.023
LAMA2	laminin, alpha 2	0.023
IGF2	insulin-like growth factor 2 (somatomedin A)	0.023
HOXC13	homeobox C13	0.023
WNT5A	wingless-type MMTV integration site family, member 5A	0.023	Human Zebrafish Mouse
PGR	progesterone receptor	0.023
MFAP4	microfibrillar-associated protein 4	0.023
FZD7	frizzled homolog 7 (Drosophila)	0.023
HOXC6	homeobox C6	0.022
COL17A1	collagen, type XVII, alpha 1	0.022
SNAI2	snail homolog 2 (Drosophila)	0.022
FOXC1	forkhead box C1	0.022
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.022
CRIP2	cysteine-rich protein 2	0.022
PITX1	paired-like homeodomain 1	0.022	Mouse
TP73	tumor protein p73	0.022
RING1	ring finger protein 1	0.022
PRKG1	protein kinase, cGMP-dependent, type I	0.022
PTRF	polymerase I and transcript release factor	0.022
DBN1	drebrin 1	0.021
CTBP2	C-terminal binding protein 2	0.021
MYO10	myosin X	0.021
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.021
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.021
CDX1	caudal type homeobox 1	0.021
EFNB1	ephrin-B1	0.021
FNDC3B	fibronectin type III domain containing 3B	0.021
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.021
ITGB4	integrin, beta 4	0.021	Human
PLAUR	plasminogen activator, urokinase receptor	0.021
FOXB1	forkhead box B1	0.021
CXCL12	chemokine (C-X-C motif) ligand 12	0.021
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.021
DUSP1	dual specificity phosphatase 1	0.021
PITX2	paired-like homeodomain 2	0.021
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.021
COMP	cartilage oligomeric matrix protein	0.020	Mouse
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.020
SORBS3	sorbin and SH3 domain containing 3	0.020
ACVR2B	activin A receptor, type IIB	0.020	Zebrafish
TMEM45A	transmembrane protein 45A	0.020
OAF	OAF homolog (Drosophila)	0.020
HOXD10	homeobox D10	0.020
EPHB3	EPH receptor B3	0.020
FOXF2	forkhead box F2	0.020
TGIF1	TGFB-induced factor homeobox 1	0.020
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.020
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.020
FGFR3	fibroblast growth factor receptor 3	0.020	Mouse
SIM2	single-minded homolog 2 (Drosophila)	0.020
CRELD2	cysteine-rich with EGF-like domains 2	0.020
HIC1	hypermethylated in cancer 1	0.020
BCOR	BCL6 corepressor	0.020
HOXB13	homeobox B13	0.019
SOX1	SRY (sex determining region Y)-box 1	0.019	Human
OTP	orthopedia homeobox	0.019
GCSH	glycine cleavage system protein H (aminomethyl carrier)	0.019
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.019
TGFBR3	transforming growth factor, beta receptor III	0.019
MYOG	myogenin (myogenic factor 4)	0.019
EN1	engrailed homeobox 1	0.019
COL7A1	collagen, type VII, alpha 1	0.019
JUB	jub, ajuba homolog (Xenopus laevis)	0.019
HDAC1	histone deacetylase 1	0.019
PCGF5	polycomb group ring finger 5	0.019
NID2	nidogen 2 (osteonidogen)	0.018
GAS1	growth arrest-specific 1	0.018
IL6	interleukin 6 (interferon, beta 2)	0.018
TCF4	transcription factor 4	0.018
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.018
ETV1	ets variant 1	0.018
GREM1	gremlin 1	0.018
SOX11	SRY (sex determining region Y)-box 11	0.018	Human
CDX2	caudal type homeobox 2	0.018
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.018
HOXC11	homeobox C11	0.017
WNT2	wingless-type MMTV integration site family member 2	0.017	Human
LGALS1	lectin, galactoside-binding, soluble, 1	0.017
THY1	Thy-1 cell surface antigen	0.017
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.017
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.017
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.017
KCTD1	potassium channel tetramerisation domain containing 1	0.017
CD248	CD248 molecule, endosialin	0.017
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.017
MEF2A	myocyte enhancer factor 2A	0.017
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.017
FBN2	fibrillin 2	0.017
CSNK1E	casein kinase 1, epsilon	0.016
HES2	hairy and enhancer of split 2 (Drosophila)	0.016	Human
COL8A2	collagen, type VIII, alpha 2	0.016
CTBP1	C-terminal binding protein 1	0.016
COL10A1	collagen, type X, alpha 1	0.016
TOP1	topoisomerase (DNA) I	0.016
EPS8	epidermal growth factor receptor pathway substrate 8	0.016
TMEM47	transmembrane protein 47	0.016
WNT3	wingless-type MMTV integration site family, member 3	0.016	Human
CTHRC1	collagen triple helix repeat containing 1	0.016
FST	follistatin	0.016
PTPRB	protein tyrosine phosphatase, receptor type, B	0.016
LAMB2	laminin, beta 2 (laminin S)	0.016
COL16A1	collagen, type XVI, alpha 1	0.016
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.016
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.016
AHR	aryl hydrocarbon receptor	0.016
COL8A1	collagen, type VIII, alpha 1	0.016
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.016
AMN	amnionless homolog (mouse)	0.015
VAX2	ventral anterior homeobox 2	0.015
PLCG1	phospholipase C, gamma 1	0.015
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.015
SOCS2	suppressor of cytokine signaling 2	0.015
HOXA13	homeobox A13	0.015
IHH	Indian hedgehog	0.015	Rat
ECEL1	endothelin converting enzyme-like 1	0.015
LIMK1	LIM domain kinase 1	0.015
WNT10A	wingless-type MMTV integration site family, member 10A	0.015	Human
MECOM	MDS1 and EVI1 complex locus	0.015
JAG2	jagged 2	0.015
NTM	neurotrimin	0.015
MNX1	motor neuron and pancreas homeobox 1	0.015
NOTCH2	notch 2	0.015	Zebrafish
SIX2	SIX homeobox 2	0.015	Mouse
AEBP1	AE binding protein 1	0.015
HOXA1	homeobox A1	0.015
FOXG1	forkhead box G1	0.015
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.015
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.015
SMO	smoothened homolog (Drosophila)	0.015	Zebrafish
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.015
BCL6	B-cell CLL/lymphoma 6	0.014
CAV1	caveolin 1, caveolae protein, 22kDa	0.014
ZNF219	zinc finger protein 219	0.014
HEG1	HEG homolog 1 (zebrafish)	0.014
PBX1	pre-B-cell leukemia homeobox 1	0.014
NGF	nerve growth factor (beta polypeptide)	0.014
LRRC15	leucine rich repeat containing 15	0.014
DIO3	deiodinase, iodothyronine, type III	0.014
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.014
BDNF	brain-derived neurotrophic factor	0.014
DLX2	distal-less homeobox 2	0.014	Mouse
NKX3-2	NK3 homeobox 2	0.014	Mouse
SLIT3	slit homolog 3 (Drosophila)	0.014
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.014
ECE1	endothelin converting enzyme 1	0.014
MOXD1	monooxygenase, DBH-like 1	0.014
FGF4	fibroblast growth factor 4	0.014
HOXD11	homeobox D11	0.014	Mouse
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.014
GATA2	GATA binding protein 2	0.014
HOXC5	homeobox C5	0.014
PAX2	paired box 2	0.014
GLI3	GLI family zinc finger 3	0.014	Mouse
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.014
CCNK	cyclin K	0.014
GLT8D2	glycosyltransferase 8 domain containing 2	0.014
CBX7	chromobox homolog 7	0.014
NEUROG2	neurogenin 2	0.014
DIO2	deiodinase, iodothyronine, type II	0.014
JAG1	jagged 1	0.014	Zebrafish
HOXA2	homeobox A2	0.014
EDN2	endothelin 2	0.013
HOXB1	homeobox B1	0.013
DPYSL3	dihydropyrimidinase-like 3	0.013
ASPN	asporin	0.013
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.013
PARVA	parvin, alpha	0.013
ESPN	espin	0.013
OLFML2B	olfactomedin-like 2B	0.013
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.013
CYR61	cysteine-rich, angiogenic inducer, 61	0.013	Mouse
AMOTL1	angiomotin like 1	0.013
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.013
BARX1	BARX homeobox 1	0.013	Zebrafish
IGF2R	insulin-like growth factor 2 receptor	0.013
ADAM11	ADAM metallopeptidase domain 11	0.013
FZD2	frizzled homolog 2 (Drosophila)	0.013
CNN3	calponin 3, acidic	0.013
TNRC6C	trinucleotide repeat containing 6C	0.013
MKL2	MKL/myocardin-like 2	0.013
HOXA11	homeobox A11	0.013	Mouse
HOXA3	homeobox A3	0.013	Mouse
GPR161	G protein-coupled receptor 161	0.013
SIX6	SIX homeobox 6	0.013
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.013
F3	coagulation factor III (thromboplastin, tissue factor)	0.013
HOXB8	homeobox B8	0.013
EGLN3	egl nine homolog 3 (C. elegans)	0.013
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.013
CLIC4	chloride intracellular channel 4	0.013
SIX5	SIX homeobox 5	0.013
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.013	Mouse
NKD1	naked cuticle homolog 1 (Drosophila)	0.013
SIRT1	sirtuin 1	0.012
SHOX	short stature homeobox	0.012
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.012
SFRP5	secreted frizzled-related protein 5	0.012
LHX5	LIM homeobox 5	0.012
NNMT	nicotinamide N-methyltransferase	0.012
HAND2	heart and neural crest derivatives expressed 2	0.012	Mouse
RAX	retina and anterior neural fold homeobox	0.012
CD63	CD63 molecule	0.012
EPHB2	EPH receptor B2	0.012
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.012
FGF19	fibroblast growth factor 19	0.012
PRSS23	protease, serine, 23	0.012
RADIL	Ras association and DIL domains	0.012
EGFL6	EGF-like-domain, multiple 6	0.012
FGF5	fibroblast growth factor 5	0.012	Human
ZEB2	zinc finger E-box binding homeobox 2	0.012
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.012
A4GALT	alpha 1,4-galactosyltransferase	0.012
TRIM9	tripartite motif containing 9	0.012
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.012
SOX21	SRY (sex determining region Y)-box 21	0.012
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.012
ACVR1B	activin A receptor, type IB	0.012	Human
CTSK	cathepsin K	0.012
AVP	arginine vasopressin	0.012
GULP1	GULP, engulfment adaptor PTB domain containing 1	0.012
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.012	Zebrafish
NFIA	nuclear factor I/A	0.012
SFRP2	secreted frizzled-related protein 2	0.012	Mouse
EPHA3	EPH receptor A3	0.012
F2R	coagulation factor II (thrombin) receptor	0.012
LENG8	leukocyte receptor cluster (LRC) member 8	0.012
TPM1	tropomyosin 1 (alpha)	0.012
IGFBP6	insulin-like growth factor binding protein 6	0.012
PGRMC1	progesterone receptor membrane component 1	0.012
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.012
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.012
GLI2	GLI family zinc finger 2	0.012	Mouse
PITX3	paired-like homeodomain 3	0.012
HDAC9	histone deacetylase 9	0.012
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.012
DUSP7	dual specificity phosphatase 7	0.012
PALLD	palladin, cytoskeletal associated protein	0.012
SLIT2	slit homolog 2 (Drosophila)	0.012
TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.012
TNRC6A	trinucleotide repeat containing 6A	0.012
PROX1	prospero homeobox 1	0.012
DLX5	distal-less homeobox 5	0.012	Zebrafish
SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.012
ANGPTL2	angiopoietin-like 2	0.012
FKBP10	FK506 binding protein 10, 65 kDa	0.012
HYAL1	hyaluronoglucosaminidase 1	0.012
EFNB3	ephrin-B3	0.012
NR2F6	nuclear receptor subfamily 2, group F, member 6	0.012
POU3F1	POU class 3 homeobox 1	0.012
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.012
MXRA8	matrix-remodelling associated 8	0.012
DPT	dermatopontin	0.011
CRABP2	cellular retinoic acid binding protein 2	0.011
HOXC10	homeobox C10	0.011
PDGFRL	platelet-derived growth factor receptor-like	0.011
FGD1	FYVE, RhoGEF and PH domain containing 1	0.011
PTBP1	polypyrimidine tract binding protein 1	0.011
HOXD1	homeobox D1	0.011
PDGFC	platelet derived growth factor C	0.011
CREBBP	CREB binding protein	0.011
OLIG2	oligodendrocyte lineage transcription factor 2	0.011
FOXL2	forkhead box L2	0.011
TLX1	T-cell leukemia homeobox 1	0.011
MAP2K6	mitogen-activated protein kinase kinase 6	0.011
EPHB4	EPH receptor B4	0.011
PMEPA1	prostate transmembrane protein, androgen induced 1	0.011
TBX5	T-box 5	0.011
HR	hairless homolog (mouse)	0.011
FOXA2	forkhead box A2	0.011
RARG	retinoic acid receptor, gamma	0.011	Mouse
STK36	serine/threonine kinase 36	0.011
PTPRU	protein tyrosine phosphatase, receptor type, U	0.011
IGF1R	insulin-like growth factor 1 receptor	0.011
BNC2	basonuclin 2	0.011
PRKCB	protein kinase C, beta	0.011
HOXB7	homeobox B7	0.011
PDX1	pancreatic and duodenal homeobox 1	0.011
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.011
FMOD	fibromodulin	0.011
BICC1	bicaudal C homolog 1 (Drosophila)	0.011
FRS2	fibroblast growth factor receptor substrate 2	0.011
WIF1	WNT inhibitory factor 1	0.011
DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.011
GLP1R	glucagon-like peptide 1 receptor	0.011
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.011
WISP2	WNT1 inducible signaling pathway protein 2	0.011
ELK1	ELK1, member of ETS oncogene family	0.011
GATA5	GATA binding protein 5	0.011
ARNT	aryl hydrocarbon receptor nuclear translocator	0.011
VASN	vasorin	0.011
FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.011
BARX2	BARX homeobox 2	0.011	Mouse
RHOD	ras homolog gene family, member D	0.011
AJAP1	adherens junctions associated protein 1	0.011
WNT4	wingless-type MMTV integration site family, member 4	0.011	Human
HTRA1	HtrA serine peptidase 1	0.011
WNT9B	wingless-type MMTV integration site family, member 9B	0.011	Human
FOXL1	forkhead box L1	0.011	Zebrafish
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011
C1S	complement component 1, s subcomponent	0.011
UNC5B	unc-5 homolog B (C. elegans)	0.011
LTK	leukocyte receptor tyrosine kinase	0.011
TAGLN	transgelin	0.011
HOXD8	homeobox D8	0.011
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.011
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.010
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.010
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.010
PLEKHA4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.010
THBS2	thrombospondin 2	0.010
SHOX2	short stature homeobox 2	0.010	Mouse
CNTFR	ciliary neurotrophic factor receptor	0.010
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.010
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.010
COL12A1	collagen, type XII, alpha 1	0.010
DLL1	delta-like 1 (Drosophila)	0.010
CD70	CD70 molecule	0.010
EWSR1	Ewing sarcoma breakpoint region 1	0.010
TWIST2	twist homolog 2 (Drosophila)	0.010
RGS3	regulator of G-protein signaling 3	0.010
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.010
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.010
PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa	0.010
TBX3	T-box 3	0.010
ATF2	activating transcription factor 2	0.010
PTK7	PTK7 protein tyrosine kinase 7	0.010
NRIP1	nuclear receptor interacting protein 1	0.010
RBM11	RNA binding motif protein 11	0.010
GEM	GTP binding protein overexpressed in skeletal muscle	0.010
COL15A1	collagen, type XV, alpha 1	0.010
FOXJ1	forkhead box J1	0.010
FAM101B	family with sequence similarity 101, member B	0.010
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.010
APC	adenomatous polyposis coli	0.010
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.010
LAMA4	laminin, alpha 4	0.010
COL4A6	collagen, type IV, alpha 6	0.010