IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

Multi-species View

tube closure

GO:0060606

Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tube closure"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "tube closure" (in gray)

Name	Description	Probability	Func Analog Organism
TSC2	tuberous sclerosis 2	0.820	Mouse
LRRK2	leucine-rich repeat kinase 2	0.796
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.742
BCOR	BCL6 corepressor	0.678
TRRAP	transformation/transcription domain-associated protein	0.649
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.628	Mouse
MEOX2	mesenchyme homeobox 2	0.548
SOX10	SRY (sex determining region Y)-box 10	0.454
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.446
BBS1	Bardet-Biedl syndrome 1	0.421
APC	adenomatous polyposis coli	0.417
MED25	mediator complex subunit 25	0.361
EP300	E1A binding protein p300	0.344
USP9X	ubiquitin specific peptidase 9, X-linked	0.337
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.333
SMAD3	SMAD family member 3	0.324
AXIN1	axin 1	0.317
SEC24D	SEC24 family, member D (S. cerevisiae)	0.286
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.277
SEC23A	Sec23 homolog A (S. cerevisiae)	0.273
CSNK1E	casein kinase 1, epsilon	0.250
AKAP11	A kinase (PRKA) anchor protein 11	0.250
RXRA	retinoid X receptor, alpha	0.244
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.242	Mouse
SETD8	SET domain containing (lysine methyltransferase) 8	0.234
KIAA1377	KIAA1377	0.218
WASF2	WAS protein family, member 2	0.215
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.211
C9orf89	chromosome 9 open reading frame 89	0.205
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.198
TSC1	tuberous sclerosis 1	0.191	Mouse
MBD2	methyl-CpG binding domain protein 2	0.190
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.182
MED29	mediator complex subunit 29	0.159
ZFX	zinc finger protein, X-linked	0.146
LDB1	LIM domain binding 1	0.145
USP22	ubiquitin specific peptidase 22	0.141
ABI1	abl-interactor 1	0.135
PUM1	pumilio homolog 1 (Drosophila)	0.133
LIN28B	lin-28 homolog B (C. elegans)	0.131
PCM1	pericentriolar material 1	0.128
ZRANB1	zinc finger, RAN-binding domain containing 1	0.117
ZFYVE9	zinc finger, FYVE domain containing 9	0.116
XIAP	X-linked inhibitor of apoptosis	0.111
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.111
CLASP2	cytoplasmic linker associated protein 2	0.110
WNT3A	wingless-type MMTV integration site family, member 3A	0.109
CARD11	caspase recruitment domain family, member 11	0.109
PEX26	peroxisomal biogenesis factor 26	0.109
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.109
BBS2	Bardet-Biedl syndrome 2	0.107
CRMP1	collapsin response mediator protein 1	0.102
MED24	mediator complex subunit 24	0.101
SMAD4	SMAD family member 4	0.099
VASP	vasodilator-stimulated phosphoprotein	0.096	Mouse
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.096
CTBP2	C-terminal binding protein 2	0.089
SORBS3	sorbin and SH3 domain containing 3	0.088
ZYX	zyxin	0.087
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.084
DLG5	discs, large homolog 5 (Drosophila)	0.082
EPAS1	endothelial PAS domain protein 1	0.080
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.079
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.077
BMP7	bone morphogenetic protein 7	0.077
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.076
GLI1	GLI family zinc finger 1	0.075
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.075
AKIP1	A kinase (PRKA) interacting protein 1	0.074
TRIP6	thyroid hormone receptor interactor 6	0.074
WT1	Wilms tumor 1	0.070
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.069
PKP4	plakophilin 4	0.069
CSNK1D	casein kinase 1, delta	0.068
WNT5A	wingless-type MMTV integration site family, member 5A	0.068	Mouse
ATXN7	ataxin 7	0.068
ANKRD28	ankyrin repeat domain 28	0.067
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.066	Mouse
BMP2	bone morphogenetic protein 2	0.065
SEC24A	SEC24 family, member A (S. cerevisiae)	0.065
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.064
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.064
WASF1	WAS protein family, member 1	0.064
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.064
GSK3B	glycogen synthase kinase 3 beta	0.062
STK36	serine/threonine kinase 36	0.061
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.061	Mouse
TADA2A	transcriptional adaptor 2A	0.060
AARSD1	alanyl-tRNA synthetase domain containing 1	0.060
KCTD1	potassium channel tetramerisation domain containing 1	0.059
FZD1	frizzled homolog 1 (Drosophila)	0.058	Mouse
MED16	mediator complex subunit 16	0.058
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.058
ZMYND11	zinc finger, MYND-type containing 11	0.058
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.057
PFN1	profilin 1	0.057	Mouse
MTMR4	myotubularin related protein 4	0.057
SMAD1	SMAD family member 1	0.054
RYR2	ryanodine receptor 2 (cardiac)	0.054
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.054
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.052
SH3BP4	SH3-domain binding protein 4	0.052
RXRB	retinoid X receptor, beta	0.052
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.051
SMAD9	SMAD family member 9	0.051
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.050
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.050
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.050
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.049
LGALS8	lectin, galactoside-binding, soluble, 8	0.049
GSK3A	glycogen synthase kinase 3 alpha	0.049
CREBBP	CREB binding protein	0.048
CEP164	centrosomal protein 164kDa	0.048
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.048
SURF4	surfeit 4	0.047
XIRP1	xin actin-binding repeat containing 1	0.047
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.047
HIC1	hypermethylated in cancer 1	0.047
FHL1	four and a half LIM domains 1	0.047
MCC	mutated in colorectal cancers	0.047
LDB2	LIM domain binding 2	0.046
GLI3	GLI family zinc finger 3	0.046
TES	testis derived transcript (3 LIM domains)	0.046	Human
FAM193A	family with sequence similarity 193, member A	0.046
BBS9	Bardet-Biedl syndrome 9	0.045
LMAN1	lectin, mannose-binding, 1	0.045
SMAD2	SMAD family member 2	0.045
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.045
HMOX2	heme oxygenase (decycling) 2	0.044
POU3F2	POU class 3 homeobox 2	0.044
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.042
DMRTB1	DMRT-like family B with proline-rich C-terminal, 1	0.042
IRAK1	interleukin-1 receptor-associated kinase 1	0.041
TPM4	tropomyosin 4	0.041
CANX	calnexin	0.041
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.040
KAT2A	K(lysine) acetyltransferase 2A	0.040	Mouse
USP24	ubiquitin specific peptidase 24	0.039
NCOA6	nuclear receptor coactivator 6	0.039
FZD8	frizzled homolog 8 (Drosophila)	0.039
TJP2	tight junction protein 2 (zona occludens 2)	0.039
ESR1	estrogen receptor 1	0.038
ACTN1	actinin, alpha 1	0.038
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.038	Mouse
HERC1	hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1	0.038
SLK	STE20-like kinase	0.038
IPO13	importin 13	0.037
NFIB	nuclear factor I/B	0.037
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.037
ZNF217	zinc finger protein 217	0.037
MED15	mediator complex subunit 15	0.037
DEDD	death effector domain containing	0.037
QPRT	quinolinate phosphoribosyltransferase	0.036
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.036
PICALM	phosphatidylinositol binding clathrin assembly protein	0.036
BAHD1	bromo adjacent homology domain containing 1	0.036
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.036
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.035
ZNF675	zinc finger protein 675	0.035
PAX6	paired box 6	0.035
ANTXR2	anthrax toxin receptor 2	0.035
RNF38	ring finger protein 38	0.034
CDK19	cyclin-dependent kinase 19	0.034
TRAM1	translocation associated membrane protein 1	0.033
GLIS3	GLIS family zinc finger 3	0.033
AKAP1	A kinase (PRKA) anchor protein 1	0.033
KANK2	KN motif and ankyrin repeat domains 2	0.033
NNT	nicotinamide nucleotide transhydrogenase	0.032
EXOC7	exocyst complex component 7	0.031
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.031
ASCC2	activating signal cointegrator 1 complex subunit 2	0.031
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.031
SIK3	SIK family kinase 3	0.031
SLC30A9	solute carrier family 30 (zinc transporter), member 9	0.030
TMED7	transmembrane emp24 protein transport domain containing 7	0.030
SP1	Sp1 transcription factor	0.030
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.030
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.029	Mouse
RBPMS	RNA binding protein with multiple splicing	0.029
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.029
ZC3H12A	zinc finger CCCH-type containing 12A	0.029
PCDH1	protocadherin 1	0.029
SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	0.029
GLI2	GLI family zinc finger 2	0.029
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.029
BBS10	Bardet-Biedl syndrome 10	0.029
TCF21	transcription factor 21	0.028
C9orf100	chromosome 9 open reading frame 100	0.028
ZNF512B	zinc finger protein 512B	0.028
MSL2	male-specific lethal 2 homolog (Drosophila)	0.028
PERP	PERP, TP53 apoptosis effector	0.028
IRAK2	interleukin-1 receptor-associated kinase 2	0.028
BRD4	bromodomain containing 4	0.028
GAS1	growth arrest-specific 1	0.028
ATXN1	ataxin 1	0.028
MAPK7	mitogen-activated protein kinase 7	0.028
MED13	mediator complex subunit 13	0.028
ZNF764	zinc finger protein 764	0.027
PITX1	paired-like homeodomain 1	0.027
NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	0.027
MED26	mediator complex subunit 26	0.027
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.027
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.027
RANBP9	RAN binding protein 9	0.027
RAD52	RAD52 homolog (S. cerevisiae)	0.027
ANKRD17	ankyrin repeat domain 17	0.027
CNN2	calponin 2	0.027
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.027
C10orf54	chromosome 10 open reading frame 54	0.027
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.027
LIMK1	LIM domain kinase 1	0.027
ZNF263	zinc finger protein 263	0.027
HELZ	helicase with zinc finger	0.027
ADARB1	adenosine deaminase, RNA-specific, B1	0.027
NELL2	NEL-like 2 (chicken)	0.026
PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	0.026
LASP1	LIM and SH3 protein 1	0.026
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.026
NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	0.026
POLQ	polymerase (DNA directed), theta	0.026
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.026
TRIM33	tripartite motif containing 33	0.026
GMEB1	glucocorticoid modulatory element binding protein 1	0.026
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.026
JUB	jub, ajuba homolog (Xenopus laevis)	0.026
DOCK9	dedicator of cytokinesis 9	0.025
PGRMC1	progesterone receptor membrane component 1	0.025
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.025
CHERP	calcium homeostasis endoplasmic reticulum protein	0.025
ATAD2B	ATPase family, AAA domain containing 2B	0.025
PLXNB1	plexin B1	0.025
NRIP1	nuclear receptor interacting protein 1	0.025
NCF1	neutrophil cytosolic factor 1	0.025
KDM5C	lysine (K)-specific demethylase 5C	0.025
HMG20A	high mobility group 20A	0.025
VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	0.025
GATAD2B	GATA zinc finger domain containing 2B	0.025
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.025
MCM3AP	minichromosome maintenance complex component 3 associated protein	0.025
CAV1	caveolin 1, caveolae protein, 22kDa	0.024
HNF4A	hepatocyte nuclear factor 4, alpha	0.024
SAP130	Sin3A-associated protein, 130kDa	0.024
KIF3B	kinesin family member 3B	0.024
ZNF746	zinc finger protein 746	0.024
NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	0.023
SCAP	SREBF chaperone	0.023
KDM2A	lysine (K)-specific demethylase 2A	0.023
RGL2	ral guanine nucleotide dissociation stimulator-like 2	0.023
FOXF2	forkhead box F2	0.023
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.023
ZC3H7A	zinc finger CCCH-type containing 7A	0.023
ZNF318	zinc finger protein 318	0.023
ARL6	ADP-ribosylation factor-like 6	0.023
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.023
FERMT2	fermitin family member 2	0.023
BRD3	bromodomain containing 3	0.023
ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	0.023
F2R	coagulation factor II (thrombin) receptor	0.023
LAMA5	laminin, alpha 5	0.023
TIFA	TRAF-interacting protein with forkhead-associated domain	0.023
DPPA2	developmental pluripotency associated 2	0.023
LIN28A	lin-28 homolog A (C. elegans)	0.023
MLF1IP	MLF1 interacting protein	0.023
GLIS2	GLIS family zinc finger 2	0.022
RARB	retinoic acid receptor, beta	0.022
ZFPM1	zinc finger protein, multitype 1	0.022
PTBP2	polypyrimidine tract binding protein 2	0.022
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.022
FZD2	frizzled homolog 2 (Drosophila)	0.022
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.022
FBXO3	F-box protein 3	0.022
PPAP2B	phosphatidic acid phosphatase type 2B	0.022
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.022
PHF3	PHD finger protein 3	0.022
ERBB2IP	erbb2 interacting protein	0.022	Human
USP21	ubiquitin specific peptidase 21	0.022
CRABP2	cellular retinoic acid binding protein 2	0.022
GPR161	G protein-coupled receptor 161	0.022
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.022
FBRSL1	fibrosin-like 1	0.022
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.022
KDM3B	lysine (K)-specific demethylase 3B	0.022
ENAH	enabled homolog (Drosophila)	0.022	Mouse
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.022
PROX1	prospero homeobox 1	0.022
MED12	mediator complex subunit 12	0.022	Mouse
GATA5	GATA binding protein 5	0.022
CDK8	cyclin-dependent kinase 8	0.022
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.022
DST	dystonin	0.022
HOXA5	homeobox A5	0.022
PAX9	paired box 9	0.022
HOXA9	homeobox A9	0.022
SIX4	SIX homeobox 4	0.022
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.021
SDC2	syndecan 2	0.021
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.021
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.021
AKAP12	A kinase (PRKA) anchor protein 12	0.021
ERF	Ets2 repressor factor	0.021
LHX2	LIM homeobox 2	0.021	Mouse
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.021
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.021
FNBP1L	formin binding protein 1-like	0.021
FZD7	frizzled homolog 7 (Drosophila)	0.021
DEFA1	defensin, alpha 1	0.021
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.021
PELI3	pellino homolog 3 (Drosophila)	0.021
BANP	BTG3 associated nuclear protein	0.021
ACVR1	activin A receptor, type I	0.021
NARS	asparaginyl-tRNA synthetase	0.021
NKD2	naked cuticle homolog 2 (Drosophila)	0.021
MYO10	myosin X	0.021
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.021
WNT4	wingless-type MMTV integration site family, member 4	0.021
ZNF576	zinc finger protein 576	0.021
DDI1	DNA-damage inducible 1 homolog 1 (S. cerevisiae)	0.021
LEF1	lymphoid enhancer-binding factor 1	0.021
NR2F6	nuclear receptor subfamily 2, group F, member 6	0.021
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.021
ZBTB8A	zinc finger and BTB domain containing 8A	0.021
TMEM44	transmembrane protein 44	0.021
SOX4	SRY (sex determining region Y)-box 4	0.021
ZFYVE26	zinc finger, FYVE domain containing 26	0.021
MYST4	MYST histone acetyltransferase (monocytic leukemia) 4	0.021
PTCH1	patched 1	0.021
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.021
EFHD2	EF-hand domain family, member D2	0.021
CHN2	chimerin (chimaerin) 2	0.021
IGSF3	immunoglobulin superfamily, member 3	0.021
TAOK1	TAO kinase 1	0.021
FAM110C	family with sequence similarity 110, member C	0.021
GEM	GTP binding protein overexpressed in skeletal muscle	0.021
TRAF3IP2	TRAF3 interacting protein 2	0.021
NUMA1	nuclear mitotic apparatus protein 1	0.021
EPHB3	EPH receptor B3	0.021
LAD1	ladinin 1	0.020
GTF2I	general transcription factor IIi	0.020
HAP1	huntingtin-associated protein 1	0.020
KIAA0368	KIAA0368	0.020
SH3RF1	SH3 domain containing ring finger 1	0.020
CFL2	cofilin 2 (muscle)	0.020
LEMD3	LEM domain containing 3	0.020
BTBD2	BTB (POZ) domain containing 2	0.020
FHOD3	formin homology 2 domain containing 3	0.020
PHF12	PHD finger protein 12	0.020
HEMGN	hemogen	0.020
DOCK1	dedicator of cytokinesis 1	0.020
HDAC10	histone deacetylase 10	0.020
SCAF8	SR-related CTD-associated factor 8	0.020
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.020
PLAGL1	pleiomorphic adenoma gene-like 1	0.020
DPYSL2	dihydropyrimidinase-like 2	0.020
GPC4	glypican 4	0.020
PRKX	protein kinase, X-linked	0.020
ANKHD1-EIF4EBP3	ANKHD1-EIF4EBP3 readthrough	0.020
RANBP10	RAN binding protein 10	0.020
FOXD1	forkhead box D1	0.020
CCDC106	coiled-coil domain containing 106	0.020
CXXC5	CXXC finger protein 5	0.020
ACY3	aspartoacylase (aminocyclase) 3	0.020
BAD	BCL2-associated agonist of cell death	0.020
FHOD1	formin homology 2 domain containing 1	0.020
MCFD2	multiple coagulation factor deficiency 2	0.020
MNS1	meiosis-specific nuclear structural 1	0.020
MYH9	myosin, heavy chain 9, non-muscle	0.020
DACH1	dachshund homolog 1 (Drosophila)	0.020
ZNF76	zinc finger protein 76	0.020
TBC1D14	TBC1 domain family, member 14	0.020
ZBED1	zinc finger, BED-type containing 1	0.020
EVC2	Ellis van Creveld syndrome 2	0.020
CADM4	cell adhesion molecule 4	0.020
SIAH1	seven in absentia homolog 1 (Drosophila)	0.020
SMO	smoothened homolog (Drosophila)	0.019
SPRED1	sprouty-related, EVH1 domain containing 1	0.019
ZMIZ1	zinc finger, MIZ-type containing 1	0.019
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.019
BTBD7	BTB (POZ) domain containing 7	0.019
FZD5	frizzled homolog 5 (Drosophila)	0.019
GJA1	gap junction protein, alpha 1, 43kDa	0.019
KIAA1522	KIAA1522	0.019
IRX4	iroquois homeobox 4	0.019
FNDC1	fibronectin type III domain containing 1	0.019
MEX3B	mex-3 homolog B (C. elegans)	0.019
KIAA0947	KIAA0947	0.019
NCOR1	nuclear receptor corepressor 1	0.019
RP2	retinitis pigmentosa 2 (X-linked recessive)	0.019
HES1	hairy and enhancer of split 1, (Drosophila)	0.019
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.019
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.019
NDRG1	N-myc downstream regulated 1	0.019
ZMYM3	zinc finger, MYM-type 3	0.019
SREBF2	sterol regulatory element binding transcription factor 2	0.019
SDCCAG3	serologically defined colon cancer antigen 3	0.019
SOX2	SRY (sex determining region Y)-box 2	0.019
HOXA11	homeobox A11	0.019
EP400	E1A binding protein p400	0.019
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.019
FOXC1	forkhead box C1	0.019
BAG3	BCL2-associated athanogene 3	0.019
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.019
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.019
FGD1	FYVE, RhoGEF and PH domain containing 1	0.019
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.019
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.019
ZCCHC14	zinc finger, CCHC domain containing 14	0.019
INO80	INO80 homolog (S. cerevisiae)	0.019
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.019
F3	coagulation factor III (thromboplastin, tissue factor)	0.019
MED14	mediator complex subunit 14	0.019
SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	0.019
HOXC5	homeobox C5	0.019
STK39	serine threonine kinase 39	0.019
ATXN7L3	ataxin 7-like 3	0.019
IRX5	iroquois homeobox 5	0.019
PRKCI	protein kinase C, iota	0.018
CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1	0.018
HES6	hairy and enhancer of split 6 (Drosophila)	0.018
CYR61	cysteine-rich, angiogenic inducer, 61	0.018
TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	0.018
ALS2	amyotrophic lateral sclerosis 2 (juvenile)	0.018
C14orf1	chromosome 14 open reading frame 1	0.018
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.018
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.018
HOXA10	homeobox A10	0.018
LRP6	low density lipoprotein receptor-related protein 6	0.018	Mouse
AKAP7	A kinase (PRKA) anchor protein 7	0.018
PLAG1	pleiomorphic adenoma gene 1	0.018
MTA1	metastasis associated 1	0.018
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.018
LHX1	LIM homeobox 1	0.018
NCOR2	nuclear receptor corepressor 2	0.018
IRX3	iroquois homeobox 3	0.018
PRRC2B	proline-rich coiled-coil 2B	0.018
HOXB3	homeobox B3	0.018
COL2A1	collagen, type II, alpha 1	0.018
BCL3	B-cell CLL/lymphoma 3	0.018
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.018
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.018
BRD1	bromodomain containing 1	0.018
PTEN	phosphatase and tensin homolog	0.018
CHD7	chromodomain helicase DNA binding protein 7	0.018
CELF2	CUGBP, Elav-like family member 2	0.018
COL12A1	collagen, type XII, alpha 1	0.018
FZD6	frizzled homolog 6 (Drosophila)	0.018	Mouse
MED1	mediator complex subunit 1	0.018
TIMP3	TIMP metallopeptidase inhibitor 3	0.018
EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.018
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.018
CIT	citron (rho-interacting, serine/threonine kinase 21)	0.018
SOX13	SRY (sex determining region Y)-box 13	0.018
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.018
IRAK3	interleukin-1 receptor-associated kinase 3	0.018
SHOX2	short stature homeobox 2	0.018
NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)	0.018
KCTD9	potassium channel tetramerisation domain containing 9	0.018
LYPD3	LY6/PLAUR domain containing 3	0.018
TSC22D4	TSC22 domain family, member 4	0.018
CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	0.018
SAV1	salvador homolog 1 (Drosophila)	0.018
CNN3	calponin 3, acidic	0.018
ZNF609	zinc finger protein 609	0.018
TRIM63	tripartite motif containing 63	0.018
CHD8	chromodomain helicase DNA binding protein 8	0.018
SIM2	single-minded homolog 2 (Drosophila)	0.018
CIC	capicua homolog (Drosophila)	0.018
RYK	RYK receptor-like tyrosine kinase	0.018
PRICKLE1	prickle homolog 1 (Drosophila)	0.018
NOTCH3	notch 3	0.018
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.018
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.018
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.018
BCL9	B-cell CLL/lymphoma 9	0.018
DIO3	deiodinase, iodothyronine, type III	0.018
ZNF692	zinc finger protein 692	0.018
KCTD15	potassium channel tetramerisation domain containing 15	0.017
FBXO30	F-box protein 30	0.017
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.017
NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	0.017
AKAP10	A kinase (PRKA) anchor protein 10	0.017
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.017
ALG12	asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)	0.017
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.017
KIAA1191	KIAA1191	0.017
PHTF2	putative homeodomain transcription factor 2	0.017
DAAM1	dishevelled associated activator of morphogenesis 1	0.017
GIGYF2	GRB10 interacting GYF protein 2	0.017
CAPRIN2	caprin family member 2	0.017
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.017
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.017
ATXN2	ataxin 2	0.017
LAMA3	laminin, alpha 3	0.017
ATP11B	ATPase, class VI, type 11B	0.017
FOXJ3	forkhead box J3	0.017
CCDC92	coiled-coil domain containing 92	0.017
EN2	engrailed homeobox 2	0.017
DLX1	distal-less homeobox 1	0.017
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.017
CDX2	caudal type homeobox 2	0.017
SEC31A	SEC31 homolog A (S. cerevisiae)	0.017
MDFI	MyoD family inhibitor	0.017
NIN	ninein (GSK3B interacting protein)	0.017
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.017	Mouse
ORC6	origin recognition complex, subunit 6	0.017
ETV4	ets variant 4	0.017
ELF4	E74-like factor 4 (ets domain transcription factor)	0.017
CENPI	centromere protein I	0.017
CHRD	chordin	0.017
RADIL	Ras association and DIL domains	0.017
PDE4DIP	phosphodiesterase 4D interacting protein	0.017
RARG	retinoic acid receptor, gamma	0.017	Mouse
EPHB4	EPH receptor B4	0.017
NEBL	nebulette	0.017
SEPT10	septin 10	0.017
NFYC	nuclear transcription factor Y, gamma	0.017
ZFP28	zinc finger protein 28 homolog (mouse)	0.017
TBX1	T-box 1	0.017
AQP7	aquaporin 7	0.017
TGFB2	transforming growth factor, beta 2	0.017
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.017
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.017
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.017
TNP2	transition protein 2 (during histone to protamine replacement)	0.017
SNAI2	snail homolog 2 (Drosophila)	0.017
KLF7	Kruppel-like factor 7 (ubiquitous)	0.017
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.017
KIAA0467	KIAA0467	0.017
TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	0.017
HSCB	HscB iron-sulfur cluster co-chaperone homolog (E. coli)	0.017
HOXD8	homeobox D8	0.017
GPC3	glypican 3	0.017
CSDA	cold shock domain protein A	0.017
TWF1	twinfilin, actin-binding protein, homolog 1 (Drosophila)	0.017
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.017
SSBP3	single stranded DNA binding protein 3	0.017
USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.017
GYG2	glycogenin 2	0.017
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.017
PMP22	peripheral myelin protein 22	0.017
LRP5	low density lipoprotein receptor-related protein 5	0.017
WDR1	WD repeat domain 1	0.017
WIF1	WNT inhibitory factor 1	0.017
STXBP2	syntaxin binding protein 2	0.017
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.017
ADCY9	adenylate cyclase 9	0.017
MED20	mediator complex subunit 20	0.017
MEF2C	myocyte enhancer factor 2C	0.017
RAG1	recombination activating gene 1	0.017
MECOM	MDS1 and EVI1 complex locus	0.017
EDNRB	endothelin receptor type B	0.017
BDNF	brain-derived neurotrophic factor	0.017
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.017
SEPT7	septin 7	0.017
PCDH18	protocadherin 18	0.017
RHPN2	rhophilin, Rho GTPase binding protein 2	0.017
NHLRC1	NHL repeat containing 1	0.017
WNT7A	wingless-type MMTV integration site family, member 7A	0.017
PDHX	pyruvate dehydrogenase complex, component X	0.017
SOX11	SRY (sex determining region Y)-box 11	0.017
EBF3	early B-cell factor 3	0.017
TLK2	tousled-like kinase 2	0.017
PTPRG	protein tyrosine phosphatase, receptor type, G	0.017
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.017
BICD1	bicaudal D homolog 1 (Drosophila)	0.017
CCDC101	coiled-coil domain containing 101	0.017
RBBP5	retinoblastoma binding protein 5	0.017
UBP1	upstream binding protein 1 (LBP-1a)	0.017
SLC20A1	solute carrier family 20 (phosphate transporter), member 1	0.017
NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	0.017
CBX4	chromobox homolog 4	0.017
TPBG	trophoblast glycoprotein	0.017
GATA4	GATA binding protein 4	0.017
PHF17	PHD finger protein 17	0.017
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.017
PFN2	profilin 2	0.016
PDZD8	PDZ domain containing 8	0.016
SOS1	son of sevenless homolog 1 (Drosophila)	0.016
MED23	mediator complex subunit 23	0.016
FAM110A	family with sequence similarity 110, member A	0.016
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.016
JAG1	jagged 1	0.016
UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)	0.016
HOXC8	homeobox C8	0.016
LRRC14	leucine rich repeat containing 14	0.016
C2orf88	chromosome 2 open reading frame 88	0.016
SALL1	sal-like 1 (Drosophila)	0.016	Mouse
TSPAN9	tetraspanin 9	0.016
BRAP	BRCA1 associated protein	0.016
SNX7	sorting nexin 7	0.016
HOXB13	homeobox B13	0.016
HOXB6	homeobox B6	0.016
SOX9	SRY (sex determining region Y)-box 9	0.016
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.016
RALGDS	ral guanine nucleotide dissociation stimulator	0.016
DNAJC13	DnaJ (Hsp40) homolog, subfamily C, member 13	0.016
ZNF592	zinc finger protein 592	0.016
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.016
PHACTR4	phosphatase and actin regulator 4	0.016
PGR	progesterone receptor	0.016
HOXC13	homeobox C13	0.016
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.016
EN1	engrailed homeobox 1	0.016
HOXB5	homeobox B5	0.016
PITX2	paired-like homeodomain 2	0.016
EPS8	epidermal growth factor receptor pathway substrate 8	0.016
SOSTDC1	sclerostin domain containing 1	0.016
C11orf49	chromosome 11 open reading frame 49	0.016
MYBL1	v-myb myeloblastosis viral oncogene homolog (avian)-like 1	0.016
EYA4	eyes absent homolog 4 (Drosophila)	0.016
ICK	intestinal cell (MAK-like) kinase	0.016
IL24	interleukin 24	0.016
HOXD9	homeobox D9	0.016
MIDN	midnolin	0.016
TRIM65	tripartite motif containing 65	0.016
ASB2	ankyrin repeat and SOCS box containing 2	0.016
SIPA1L3	signal-induced proliferation-associated 1 like 3	0.016
PAQR9	progestin and adipoQ receptor family member IX	0.016
WDR44	WD repeat domain 44	0.016
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.016
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.016
JMJD1C	jumonji domain containing 1C	0.016
RXRG	retinoid X receptor, gamma	0.016
PELI1	pellino homolog 1 (Drosophila)	0.016
BNC1	basonuclin 1	0.016
EID1	EP300 interacting inhibitor of differentiation 1	0.016
MYO18A	myosin XVIIIA	0.016
HOXD13	homeobox D13	0.016
PCDH10	protocadherin 10	0.016
PBX1	pre-B-cell leukemia homeobox 1	0.016
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.016
WWC1	WW and C2 domain containing 1	0.016
NPAS1	neuronal PAS domain protein 1	0.016
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.016
AFTPH	aftiphilin	0.016
RND3	Rho family GTPase 3	0.016
C16orf48	chromosome 16 open reading frame 48	0.016
NIPBL	Nipped-B homolog (Drosophila)	0.016
PRDM13	PR domain containing 13	0.016
KIAA1543	KIAA1543	0.016
AKAP5	A kinase (PRKA) anchor protein 5	0.016
TOB1	transducer of ERBB2, 1	0.016
EYA2	eyes absent homolog 2 (Drosophila)	0.016
ACSL4	acyl-CoA synthetase long-chain family member 4	0.016
FBLN1	fibulin 1	0.016
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.016
GAPVD1	GTPase activating protein and VPS9 domains 1	0.016
FAM176A	family with sequence similarity 176, member A	0.016
TADA3	transcriptional adaptor 3	0.016
ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	0.016
ZBTB48	zinc finger and BTB domain containing 48	0.016
PRDM6	PR domain containing 6	0.016
CCNO	cyclin O	0.016
PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	0.016
CREB5	cAMP responsive element binding protein 5	0.016
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.016
PFDN1	prefoldin subunit 1	0.016
XPC	xeroderma pigmentosum, complementation group C	0.016
CD24	CD24 molecule	0.016
COTL1	coactosin-like 1 (Dictyostelium)	0.016
SAP30L	SAP30-like	0.016
ZNF532	zinc finger protein 532	0.016
TNS3	tensin 3	0.016
PHKA2	phosphorylase kinase, alpha 2 (liver)	0.016
BMP6	bone morphogenetic protein 6	0.016
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.016
STC2	stanniocalcin 2	0.016
LSR	lipolysis stimulated lipoprotein receptor	0.016
ZNF521	zinc finger protein 521	0.016
KEAP1	kelch-like ECH-associated protein 1	0.016
ZNF350	zinc finger protein 350	0.016
VASH2	vasohibin 2	0.016
SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	0.016
IRX1	iroquois homeobox 1	0.016
FOXL2	forkhead box L2	0.016
PRUNE2	prune homolog 2 (Drosophila)	0.016
PAX2	paired box 2	0.016	Mouse
BBS7	Bardet-Biedl syndrome 7	0.016
MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)	0.016
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.016
MN1	meningioma (disrupted in balanced translocation) 1	0.016
PCDHA4	protocadherin alpha 4	0.016
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.015
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.015
FAM83B	family with sequence similarity 83, member B	0.015
TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)	0.015
BCL6	B-cell CLL/lymphoma 6	0.015
MEF2A	myocyte enhancer factor 2A	0.015
ASXL2	additional sex combs like 2 (Drosophila)	0.015
HOXC6	homeobox C6	0.015
GPHN	gephyrin	0.015
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.015
TBX3	T-box 3	0.015
SLIT2	slit homolog 2 (Drosophila)	0.015
FAM129A	family with sequence similarity 129, member A	0.015
SFRP1	secreted frizzled-related protein 1	0.015	Mouse
TSHZ1	teashirt zinc finger homeobox 1	0.015
PDGFRL	platelet-derived growth factor receptor-like	0.015
SEC16A	SEC16 homolog A (S. cerevisiae)	0.015
SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	0.015
FOXH1	forkhead box H1	0.015
TPD52L1	tumor protein D52-like 1	0.015
BAI1	brain-specific angiogenesis inhibitor 1	0.015
POGK	pogo transposable element with KRAB domain	0.015
CC2D1A	coiled-coil and C2 domain containing 1A	0.015
GATA2	GATA binding protein 2	0.015
TMEM158	transmembrane protein 158 (gene/pseudogene)	0.015
TRPS1	trichorhinophalangeal syndrome I	0.015
LCOR	ligand dependent nuclear receptor corepressor	0.015
DAZAP1	DAZ associated protein 1	0.015
EPHA4	EPH receptor A4	0.015
GPC6	glypican 6	0.015
RSU1	Ras suppressor protein 1	0.015
MYO1B	myosin IB	0.015
RPAP1	RNA polymerase II associated protein 1	0.015
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.015
PTPRK	protein tyrosine phosphatase, receptor type, K	0.015
HDGFRP3	hepatoma-derived growth factor, related protein 3	0.015
PLS3	plastin 3	0.015
ZBTB10	zinc finger and BTB domain containing 10	0.015
CLINT1	clathrin interactor 1	0.015
SERTAD2	SERTA domain containing 2	0.015
VSX1	visual system homeobox 1	0.015
NKX2-1	NK2 homeobox 1	0.015
TMEM131	transmembrane protein 131	0.015
ARL2BP	ADP-ribosylation factor-like 2 binding protein	0.015
ZNF219	zinc finger protein 219	0.015
CENPJ	centromere protein J	0.015
THSD4	thrombospondin, type I, domain containing 4	0.015
HOXC10	homeobox C10	0.015
ARHGAP31	Rho GTPase activating protein 31	0.015
SETD2	SET domain containing 2	0.015	Mouse
GATA6	GATA binding protein 6	0.015
EFNA5	ephrin-A5	0.015
OSR2	odd-skipped related 2 (Drosophila)	0.015
PPARA	peroxisome proliferator-activated receptor alpha	0.015
HOXD11	homeobox D11	0.015
C3orf70	chromosome 3 open reading frame 70	0.015
CNIH3	cornichon homolog 3 (Drosophila)	0.015
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.015
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.015
EFNA3	ephrin-A3	0.015
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.015
PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.015
PTPRM	protein tyrosine phosphatase, receptor type, M	0.015
RPRD2	regulation of nuclear pre-mRNA domain containing 2	0.015
ISL1	ISL LIM homeobox 1	0.015
GPM6B	glycoprotein M6B	0.015
IFT140	intraflagellar transport 140 homolog (Chlamydomonas)	0.015
ONECUT2	one cut homeobox 2	0.015
PSKH1	protein serine kinase H1	0.015