IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

Multi-species View

branch elongation of an epithelium

GO:0060602

The growth process in which a branch increases in length from its base to its tip.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "branch elongation of an epithelium"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "branch elongation of an epithelium" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.998
FGF10	fibroblast growth factor 10	0.993
FSTL1	follistatin-like 1	0.969
FGFR1	fibroblast growth factor receptor 1	0.943
FGF7	fibroblast growth factor 7	0.943	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.885
SH3KBP1	SH3-domain kinase binding protein 1	0.370
S100A4	S100 calcium binding protein A4	0.297
ENG	endoglin	0.297
S100A2	S100 calcium binding protein A2	0.286
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.263
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.117
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.112
FGFR3	fibroblast growth factor receptor 3	0.109
FGF2	fibroblast growth factor 2 (basic)	0.107	Human
THBS1	thrombospondin 1	0.107
MED10	mediator complex subunit 10	0.101
FGF8	fibroblast growth factor 8 (androgen-induced)	0.096
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.091
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.089
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.087
RARA	retinoic acid receptor, alpha	0.085
SPRY2	sprouty homolog 2 (Drosophila)	0.075	Mouse
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.071
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.064
TGFBR1	transforming growth factor, beta receptor 1	0.063
TGFB3	transforming growth factor, beta 3	0.060
TGFB2	transforming growth factor, beta 2	0.050
MED29	mediator complex subunit 29	0.049
FZD1	frizzled homolog 1 (Drosophila)	0.048
CDK19	cyclin-dependent kinase 19	0.048
FRS2	fibroblast growth factor receptor substrate 2	0.047
ESR2	estrogen receptor 2 (ER beta)	0.044
FST	follistatin	0.044
FZD7	frizzled homolog 7 (Drosophila)	0.044
TRRAP	transformation/transcription domain-associated protein	0.042
SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	0.040	Mouse
HNF4A	hepatocyte nuclear factor 4, alpha	0.038
DNM2	dynamin 2	0.035
MDFI	MyoD family inhibitor	0.034
ATF3	activating transcription factor 3	0.033
ZFYVE9	zinc finger, FYVE domain containing 9	0.033
EYA2	eyes absent homolog 2 (Drosophila)	0.032
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.031
FGF3	fibroblast growth factor 3	0.026	Human
CTGF	connective tissue growth factor	0.026
FGF4	fibroblast growth factor 4	0.026	Human
TOP1	topoisomerase (DNA) I	0.025
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.024
C9orf25	chromosome 9 open reading frame 25	0.024
SPRY4	sprouty homolog 4 (Drosophila)	0.024
SH3GL2	SH3-domain GRB2-like 2	0.024
BMPR1B	bone morphogenetic protein receptor, type IB	0.023
CDK8	cyclin-dependent kinase 8	0.023
EYA1	eyes absent homolog 1 (Drosophila)	0.023
WNT1	wingless-type MMTV integration site family, member 1	0.023
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.022
FGFBP1	fibroblast growth factor binding protein 1	0.022
RXRA	retinoid X receptor, alpha	0.020
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.020
SH2B2	SH2B adaptor protein 2	0.020
TGFBR3	transforming growth factor, beta receptor III	0.020
FOXA2	forkhead box A2	0.019
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.019
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.019
TGS1	trimethylguanosine synthase 1	0.019
HOXD11	homeobox D11	0.018
SIM2	single-minded homolog 2 (Drosophila)	0.017
TNPO1	transportin 1	0.017
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.017
F3	coagulation factor III (thromboplastin, tissue factor)	0.017
HAS2	hyaluronan synthase 2	0.017
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.017
TADA2A	transcriptional adaptor 2A	0.017
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.016
RBM25	RNA binding motif protein 25	0.016
HOXB9	homeobox B9	0.015
COL2A1	collagen, type II, alpha 1	0.015
CNTN1	contactin 1	0.015
BDNF	brain-derived neurotrophic factor	0.015
NXF1	nuclear RNA export factor 1	0.015
FGFR4	fibroblast growth factor receptor 4	0.015
HOXA11	homeobox A11	0.015
HIPK2	homeodomain interacting protein kinase 2	0.015
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.015
FGF19	fibroblast growth factor 19	0.015
SDC2	syndecan 2	0.014
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.014
DDN	dendrin	0.014
VEZT	vezatin, adherens junctions transmembrane protein	0.014
EDN1	endothelin 1	0.014
CHM	choroideremia (Rab escort protein 1)	0.014
PTH	parathyroid hormone	0.014
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.014
SFRP5	secreted frizzled-related protein 5	0.013
EEA1	early endosome antigen 1	0.013
HOXD12	homeobox D12	0.013
KAL1	Kallmann syndrome 1 sequence	0.013
HOXD10	homeobox D10	0.013
HOXB5	homeobox B5	0.013
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.013
HNF1A	HNF1 homeobox A	0.013
PAX8	paired box 8	0.013
USP42	ubiquitin specific peptidase 42	0.013
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.013
SIX2	SIX homeobox 2	0.013
NOVA1	neuro-oncological ventral antigen 1	0.013
DUSP6	dual specificity phosphatase 6	0.013
SPRED2	sprouty-related, EVH1 domain containing 2	0.013
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.013
SH3BP2	SH3-domain binding protein 2	0.013
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.012
FGF6	fibroblast growth factor 6	0.012	Human
SH3GL3	SH3-domain GRB2-like 3	0.012
FOXL1	forkhead box L1	0.012
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.012
WNT3	wingless-type MMTV integration site family, member 3	0.012
FZD8	frizzled homolog 8 (Drosophila)	0.012
BMP2	bone morphogenetic protein 2	0.012	Human
HAND2	heart and neural crest derivatives expressed 2	0.012
CER1	cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)	0.012
SOX2	SRY (sex determining region Y)-box 2	0.012
HOXD9	homeobox D9	0.012
RHO	rhodopsin	0.012
TRIM2	tripartite motif containing 2	0.012
ERAS	ES cell expressed Ras	0.012
CDK12	cyclin-dependent kinase 12	0.012
HES1	hairy and enhancer of split 1, (Drosophila)	0.012
ALCAM	activated leukocyte cell adhesion molecule	0.012
SFRP1	secreted frizzled-related protein 1	0.012
KLHDC5	kelch domain containing 5	0.012
EPHA4	EPH receptor A4	0.011
MED19	mediator complex subunit 19	0.011
SOX4	SRY (sex determining region Y)-box 4	0.011
FOXN4	forkhead box N4	0.011
MED25	mediator complex subunit 25	0.011
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.011
MED14	mediator complex subunit 14	0.011
SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.011
HMGA2	high mobility group AT-hook 2	0.011
ANUBL1	AN1, ubiquitin-like, homolog (Xenopus laevis)	0.011
PGR	progesterone receptor	0.011
ZFHX4	zinc finger homeobox 4	0.011
MED27	mediator complex subunit 27	0.011
NEUROG1	neurogenin 1	0.011
UTF1	undifferentiated embryonic cell transcription factor 1	0.011
JAG1	jagged 1	0.011
EVX1	even-skipped homeobox 1	0.011
GDNF	glial cell derived neurotrophic factor	0.011
SALL1	sal-like 1 (Drosophila)	0.011
T	T, brachyury homolog (mouse)	0.011
NRP1	neuropilin 1	0.011
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.011
RBBP5	retinoblastoma binding protein 5	0.011
HOXC13	homeobox C13	0.011
CXCL3	chemokine (C-X-C motif) ligand 3	0.011
BLNK	B-cell linker	0.011
ETV1	ets variant 1	0.011
DIO3	deiodinase, iodothyronine, type III	0.011
SYNJ2	synaptojanin 2	0.011
PML	promyelocytic leukemia	0.011
PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	0.011
FOXD3	forkhead box D3	0.011
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.011
SIX3	SIX homeobox 3	0.011
CALB1	calbindin 1, 28kDa	0.011
ANXA3	annexin A3	0.011
PAX3	paired box 3	0.011
S100A1	S100 calcium binding protein A1	0.011
KCNK2	potassium channel, subfamily K, member 2	0.011
MOS	v-mos Moloney murine sarcoma viral oncogene homolog	0.011
BMP4	bone morphogenetic protein 4	0.011
PLCE1	phospholipase C, epsilon 1	0.011
ALX1	ALX homeobox 1	0.011
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.010
TRIM32	tripartite motif containing 32	0.010
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.010
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.010
KANK2	KN motif and ankyrin repeat domains 2	0.010
EPHA5	EPH receptor A5	0.010
PSG9	pregnancy specific beta-1-glycoprotein 9	0.010
HOXC8	homeobox C8	0.010
MYO10	myosin X	0.010
PAX7	paired box 7	0.010
HBEGF	heparin-binding EGF-like growth factor	0.010
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.010
HOXA13	homeobox A13	0.010
SUMF2	sulfatase modifying factor 2	0.010
BMP6	bone morphogenetic protein 6	0.010
THRAP3	thyroid hormone receptor associated protein 3	0.010
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.010
SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	0.010
PLCG1	phospholipase C, gamma 1	0.010
RET	ret proto-oncogene	0.010
MED6	mediator complex subunit 6	0.010
NKX2-1	NK2 homeobox 1	0.010
BTC	betacellulin	0.010
MED20	mediator complex subunit 20	0.010
PDCD6IP	programmed cell death 6 interacting protein	0.010
ETV4	ets variant 4	0.010
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.010