IMP: Integrative Multi-species Prediction

Homo sapiens

35 genes annotated in human

positive regulation of proteolysis involved in cellular protein catabolic process

GO:1903052

Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of proteolysis involved in cellular protein catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of proteolysis involved in cellular protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.998	Yeast
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.982
SMAD4	SMAD family member 4	0.946	Human
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.915	Yeast Fly
SMAD3	SMAD family member 3	0.876	Human
SMAD2	SMAD family member 2	0.823	Human
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.790
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.740	Human
TP53	tumor protein p53	0.718
ADRM1	adhesion regulating molecule 1	0.702
UBC	ubiquitin C	0.690
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.658	Human
SMAD1	SMAD family member 1	0.643	Human
SMAD5	SMAD family member 5	0.636	Human
CSNK1E	casein kinase 1, epsilon	0.607	Mouse Fly
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.598
GSK3B	glycogen synthase kinase 3 beta	0.573	Mouse Fly
CUL2	cullin 2	0.481
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.466
SMAD7	SMAD family member 7	0.459
UBQLN1	ubiquilin 1	0.432
ANAPC4	anaphase promoting complex subunit 4	0.426
RNF11	ring finger protein 11	0.423
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.399
PIAS4	protein inhibitor of activated STAT, 4	0.320
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.267
EPOR	erythropoietin receptor	0.266
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.245
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.231	Human
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.215
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.210
SKIL	SKI-like oncogene	0.206
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.203
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.195
PTK2	PTK2 protein tyrosine kinase 2	0.194	Mouse
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.194
TADA3	transcriptional adaptor 3	0.184
SMC6	structural maintenance of chromosomes 6	0.183
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.183
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.180
ANAPC11	anaphase promoting complex subunit 11	0.178
PSEN1	presenilin 1	0.176	Mouse
PLK1	polo-like kinase 1	0.156
BBS10	Bardet-Biedl syndrome 10	0.156
PSEN2	presenilin 2 (Alzheimer disease 4)	0.154	Mouse
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.146
CUL5	cullin 5	0.145
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.143	Yeast
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.137
AURKB	aurora kinase B	0.136
JUN	jun proto-oncogene	0.126
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.126
ATXN3	ataxin 3	0.125
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.122
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.117
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.116	Yeast
HDAC6	histone deacetylase 6	0.108
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.107	Fly
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.106
PRNP	prion protein	0.097
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.091	Yeast
DAXX	death-domain associated protein	0.089
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.089
CSNK1D	casein kinase 1, delta	0.087	Mouse Fly
SOCS2	suppressor of cytokine signaling 2	0.086	Human
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.085
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.084
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.084
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.083
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.079
ANAPC7	anaphase promoting complex subunit 7	0.079
BRCA1	breast cancer 1, early onset	0.077
CUL1	cullin 1	0.077
XIAP	X-linked inhibitor of apoptosis	0.076
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.073	Yeast
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.073
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.072
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.072
RBBP8	retinoblastoma binding protein 8	0.070
ADRBK1	adrenergic, beta, receptor kinase 1	0.069
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.067
PDCD10	programmed cell death 10	0.065
PDCD6IP	programmed cell death 6 interacting protein	0.065
AXIN1	axin 1	0.065	Mouse Rat
CDK2	cyclin-dependent kinase 2	0.064
PTTG1	pituitary tumor-transforming 1	0.063
HSPB1	heat shock 27kDa protein 1	0.063
GCLM	glutamate-cysteine ligase, modifier subunit	0.062
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.062	Fly
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.061
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.061
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.060
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.060
ATF5	activating transcription factor 5	0.058
SOCS1	suppressor of cytokine signaling 1	0.057	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.056
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.056
ZNF746	zinc finger protein 746	0.056
RAD23B	RAD23 homolog B (S. cerevisiae)	0.055
BAG2	BCL2-associated athanogene 2	0.054
JAK2	Janus kinase 2	0.053
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.053
BAG1	BCL2-associated athanogene	0.052
ZFYVE9	zinc finger, FYVE domain containing 9	0.051
RCHY1	ring finger and CHY zinc finger domain containing 1	0.051
VHL	von Hippel-Lindau tumor suppressor	0.051
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.051	Human Mouse
STIP1	stress-induced-phosphoprotein 1	0.050
SOCS3	suppressor of cytokine signaling 3	0.050	Human
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.049
TBP	TATA box binding protein	0.048
EEF2	eukaryotic translation elongation factor 2	0.048
FYN	FYN oncogene related to SRC, FGR, YES	0.047
TUBA1C	tubulin, alpha 1c	0.046
RBL2	retinoblastoma-like 2 (p130)	0.043	Human
RB1	retinoblastoma 1	0.043
ERBB2IP	erbb2 interacting protein	0.043
HSPA4	heat shock 70kDa protein 4	0.043
FUNDC2	FUN14 domain containing 2	0.042
FBXL15	F-box and leucine-rich repeat protein 15	0.040
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.040
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.040
CXXC5	CXXC finger protein 5	0.039
BCAR1	breast cancer anti-estrogen resistance 1	0.039
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.039	Fly
CREBBP	CREB binding protein	0.038
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.038
MAK	male germ cell-associated kinase	0.038
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.038
MBD1	methyl-CpG binding domain protein 1	0.037
CDT1	chromatin licensing and DNA replication factor 1	0.036
SIRT2	sirtuin 2	0.036
TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	0.035
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.035	Yeast
JUNB	jun B proto-oncogene	0.035
LRP6	low density lipoprotein receptor-related protein 6	0.035
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.035
CLSPN	claspin	0.035
HSPA8	heat shock 70kDa protein 8	0.034
RBL1	retinoblastoma-like 1 (p107)	0.034	Human
UBE2S	ubiquitin-conjugating enzyme E2S	0.033
BBS9	Bardet-Biedl syndrome 9	0.033
E2F5	E2F transcription factor 5, p130-binding	0.033
RHOA	ras homolog gene family, member A	0.033
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.033
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.032
SMC1A	structural maintenance of chromosomes 1A	0.031
STAG1	stromal antigen 1	0.031
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.031
ANAPC1	anaphase promoting complex subunit 1	0.030
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.030
LRRK2	leucine-rich repeat kinase 2	0.030	Mouse
UBE3A	ubiquitin protein ligase E3A	0.030	Fly
POLH	polymerase (DNA directed), eta	0.030
SAE1	SUMO1 activating enzyme subunit 1	0.030
TGFBR1	transforming growth factor, beta receptor 1	0.029
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.029
ANAPC5	anaphase promoting complex subunit 5	0.029
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.029
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.029
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.028
RGS2	regulator of G-protein signaling 2, 24kDa	0.028
MATK	megakaryocyte-associated tyrosine kinase	0.028
AR	androgen receptor	0.028
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.028
DDIT3	DNA-damage-inducible transcript 3	0.028
E2F4	E2F transcription factor 4, p107/p130-binding	0.028
GORAB	golgin, RAB6-interacting	0.027
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.027
BCL2	B-cell CLL/lymphoma 2	0.027
CCND1	cyclin D1	0.026
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.026
EIF1B	eukaryotic translation initiation factor 1B	0.026
MAP1A	microtubule-associated protein 1A	0.026
CDK9	cyclin-dependent kinase 9	0.026
CUL4A	cullin 4A	0.026
ATF3	activating transcription factor 3	0.025
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.025
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.024
TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	0.024
EPS15	epidermal growth factor receptor pathway substrate 15	0.024
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.024
C1D	C1D nuclear receptor corepressor	0.024
FLNB	filamin B, beta	0.024
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.024
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.024
SPTBN4	spectrin, beta, non-erythrocytic 4	0.023
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.023
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.023
ANKRD13A	ankyrin repeat domain 13A	0.022
CCNA2	cyclin A2	0.022
POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	0.022
CCNE1	cyclin E1	0.022
TRAF4	TNF receptor-associated factor 4	0.022
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.022
CCNB1	cyclin B1	0.022
UBASH3B	ubiquitin associated and SH3 domain containing B	0.022
SNIP1	Smad nuclear interacting protein 1	0.022
BCL2L1	BCL2-like 1	0.021
SMAD6	SMAD family member 6	0.021	Human
SHPRH	SNF2 histone linker PHD RING helicase	0.021
RANBP9	RAN binding protein 9	0.021
HSPA13	heat shock protein 70kDa family, member 13	0.021
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.021
BTBD2	BTB (POZ) domain containing 2	0.021
PUF60	poly-U binding splicing factor 60KDa	0.021
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.021
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.021
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.021
TRIM63	tripartite motif containing 63	0.021
HSF1	heat shock transcription factor 1	0.020
FAF2	Fas associated factor family member 2	0.020
APP	amyloid beta (A4) precursor protein	0.020
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.020
MEMO1	mediator of cell motility 1	0.020
HDAC11	histone deacetylase 11	0.020
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.020
AXIN2	axin 2	0.020
FEM1B	fem-1 homolog b (C. elegans)	0.020
CCDC6	coiled-coil domain containing 6	0.020
WNK1	WNK lysine deficient protein kinase 1	0.019
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.019
JUND	jun D proto-oncogene	0.019
PSRC1	proline/serine-rich coiled-coil 1	0.019
PRKCZ	protein kinase C, zeta	0.019
ANAPC13	anaphase promoting complex subunit 13	0.019
POMP	proteasome maturation protein	0.019
CEP164	centrosomal protein 164kDa	0.019
ADAM15	ADAM metallopeptidase domain 15	0.019
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.018
SOX7	SRY (sex determining region Y)-box 7	0.018
E2F1	E2F transcription factor 1	0.018
ARIH2	ariadne homolog 2 (Drosophila)	0.018
GHR	growth hormone receptor	0.018
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.018
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.018
RPL11	ribosomal protein L11	0.018
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.018
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.018
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.018
DDB1	damage-specific DNA binding protein 1, 127kDa	0.017
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.017
ZHX1	zinc fingers and homeoboxes 1	0.017
UBXN7	UBX domain protein 7	0.017
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.017
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.017
SETDB1	SET domain, bifurcated 1	0.017
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.017
WT1	Wilms tumor 1	0.017
TTC35	tetratricopeptide repeat domain 35	0.017
MAP1S	microtubule-associated protein 1S	0.017
MYO6	myosin VI	0.017
PIAS2	protein inhibitor of activated STAT, 2	0.017
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.017
CAV1	caveolin 1, caveolae protein, 22kDa	0.016
ZFAND5	zinc finger, AN1-type domain 5	0.016
SYNE1	spectrin repeat containing, nuclear envelope 1	0.016
RAP1B	RAP1B, member of RAS oncogene family	0.016
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.016
AIG1	androgen-induced 1	0.016
RFWD2	ring finger and WD repeat domain 2	0.016
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.016
MARCH5	membrane-associated ring finger (C3HC4) 5	0.016
ARHGAP5	Rho GTPase activating protein 5	0.016
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.016
WWOX	WW domain containing oxidoreductase	0.016
SRCIN1	SRC kinase signaling inhibitor 1	0.016
RNF111	ring finger protein 111	0.015
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.015
SKP1	S-phase kinase-associated protein 1	0.015
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.015
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.015
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.015
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.015
USPL1	ubiquitin specific peptidase like 1	0.015
MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	0.015
SKA1	spindle and kinetochore associated complex subunit 1	0.015
YAP1	Yes-associated protein 1	0.015
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.015
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.015
IL12RB2	interleukin 12 receptor, beta 2	0.015
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.015
NCSTN	nicastrin	0.015
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.015	Yeast
PIM1	pim-1 oncogene	0.015
KLHL12	kelch-like 12 (Drosophila)	0.015
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.014
MCC	mutated in colorectal cancers	0.014
BHLHE40	basic helix-loop-helix family, member e40	0.014
LIN54	lin-54 homolog (C. elegans)	0.014
TROAP	trophinin associated protein (tastin)	0.014
CENPF	centromere protein F, 350/400kDa (mitosin)	0.014
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.014
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.014
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.014
FBXO5	F-box protein 5	0.014
TNK2	tyrosine kinase, non-receptor, 2	0.014
MAP2K6	mitogen-activated protein kinase kinase 6	0.014
S100A4	S100 calcium binding protein A4	0.014
PIAS3	protein inhibitor of activated STAT, 3	0.014
RYBP	RING1 and YY1 binding protein	0.014
MAPT	microtubule-associated protein tau	0.014
KLF5	Kruppel-like factor 5 (intestinal)	0.014
FAM82A2	family with sequence similarity 82, member A2	0.014
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.014
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.014
UBQLN2	ubiquilin 2	0.014
RAD23A	RAD23 homolog A (S. cerevisiae)	0.014
MED28	mediator complex subunit 28	0.014
NLK	nemo-like kinase	0.014
MYST2	MYST histone acetyltransferase 2	0.014
STAG2	stromal antigen 2	0.014
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.014
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.014
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.014
HSPA2	heat shock 70kDa protein 2	0.014
SENP1	SUMO1/sentrin specific peptidase 1	0.013
ARL15	ADP-ribosylation factor-like 15	0.013
GTF2F1	general transcription factor IIF, polypeptide 1, 74kDa	0.013
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.013
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.013
BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)	0.013
TIAM1	T-cell lymphoma invasion and metastasis 1	0.013
NDFIP2	Nedd4 family interacting protein 2	0.013
ING2	inhibitor of growth family, member 2	0.013
TRADD	TNFRSF1A-associated via death domain	0.013
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.013
SOCS4	suppressor of cytokine signaling 4	0.013	Human
HMGB2	high mobility group box 2	0.013
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.013
USP2	ubiquitin specific peptidase 2	0.013	Fly
GFI1B	growth factor independent 1B transcription repressor	0.013
SCAF11	SR-related CTD-associated factor 11	0.013
CASP8AP2	caspase 8 associated protein 2	0.013
POLR2C	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	0.013
RNF168	ring finger protein 168	0.013
ARRDC3	arrestin domain containing 3	0.013
PTPRS	protein tyrosine phosphatase, receptor type, S	0.012
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.012
PRC1	protein regulator of cytokinesis 1	0.012
TTK	TTK protein kinase	0.012
PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
BEND5	BEN domain containing 5	0.012
ANAPC10	anaphase promoting complex subunit 10	0.012	Yeast
SIAH1	seven in absentia homolog 1 (Drosophila)	0.012
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.012	Fly
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.012
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.012
CCDC101	coiled-coil domain containing 101	0.012
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.012
SRI	sorcin	0.012
RAD21	RAD21 homolog (S. pombe)	0.012
FNBP1L	formin binding protein 1-like	0.012
UBA1	ubiquitin-like modifier activating enzyme 1	0.012
RAB5B	RAB5B, member RAS oncogene family	0.012
CDCA3	cell division cycle associated 3	0.012
MMS22L	MMS22-like, DNA repair protein	0.012
FRMD6	FERM domain containing 6	0.012
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.012
ENY2	enhancer of yellow 2 homolog (Drosophila)	0.012
NCK2	NCK adaptor protein 2	0.012
MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	0.012
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.012
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.012
ETV5	ets variant 5	0.012
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.012
MAP1B	microtubule-associated protein 1B	0.011
USP9X	ubiquitin specific peptidase 9, X-linked	0.011
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.011
TRIM32	tripartite motif containing 32	0.011
TIFA	TRAF-interacting protein with forkhead-associated domain	0.011
KALRN	kalirin, RhoGEF kinase	0.011
PTEN	phosphatase and tensin homolog	0.011
CCDC141	coiled-coil domain containing 141	0.011
E2F2	E2F transcription factor 2	0.011
KIF1B	kinesin family member 1B	0.011
KIF18A	kinesin family member 18A	0.011
RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	0.011
MAX	MYC associated factor X	0.011
ZNF512B	zinc finger protein 512B	0.011
UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	0.011
TUBA1A	tubulin, alpha 1a	0.011
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.011
DOCK8	dedicator of cytokinesis 8	0.011
MYST1	MYST histone acetyltransferase 1	0.011
UBASH3A	ubiquitin associated and SH3 domain containing A	0.011
VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	0.011
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.011
FBP1	fructose-1,6-bisphosphatase 1	0.011
FAM83D	family with sequence similarity 83, member D	0.011
PINK1	PTEN induced putative kinase 1	0.011
TGFB1	transforming growth factor, beta 1	0.011
FES	feline sarcoma oncogene	0.011
SETD7	SET domain containing (lysine methyltransferase) 7	0.011
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.011
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.011
MKL2	MKL/myocardin-like 2	0.011
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.011
UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	0.011
EXT2	exostosin 2	0.011
KCTD3	potassium channel tetramerisation domain containing 3	0.011
EPHA8	EPH receptor A8	0.011
LRIF1	ligand dependent nuclear receptor interacting factor 1	0.011
DEDD	death effector domain containing	0.011
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.011
CSNK1A1	casein kinase 1, alpha 1	0.011	Fly
TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	0.011
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.011
GMEB1	glucocorticoid modulatory element binding protein 1	0.011
DYNLL1	dynein, light chain, LC8-type 1	0.010
USP20	ubiquitin specific peptidase 20	0.010
BAHD1	bromo adjacent homology domain containing 1	0.010
NEFL	neurofilament, light polypeptide	0.010
RANGAP1	Ran GTPase activating protein 1	0.010
CDKN3	cyclin-dependent kinase inhibitor 3	0.010
JAM2	junctional adhesion molecule 2	0.010
ZNF295	zinc finger protein 295	0.010
USP5	ubiquitin specific peptidase 5 (isopeptidase T)	0.010
FHL2	four and a half LIM domains 2	0.010
DLG4	discs, large homolog 4 (Drosophila)	0.010
RBM4	RNA binding motif protein 4	0.010
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.010
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.010
PML	promyelocytic leukemia	0.010
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.010
DEPDC1	DEP domain containing 1	0.010
FRZB	frizzled-related protein	0.010
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.010
AAAS	achalasia, adrenocortical insufficiency, alacrimia	0.010
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.010
CISH	cytokine inducible SH2-containing protein	0.010	Human
ADRB2	adrenergic, beta-2-, receptor, surface	0.010
MAGEA2	melanoma antigen family A, 2	0.010
PRUNE	prune homolog (Drosophila)	0.010
ACVR1	activin A receptor, type I	0.010
MLF2	myeloid leukemia factor 2	0.010