4 genes annotated in humanMulti-species View
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "srebp signaling pathway"
|Name||Description||Probability||Func Analog Organism|
|HMGCS1||3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)||0.045|
|IDI1||isopentenyl-diphosphate delta isomerase 1||0.035|
|CYP51A1||cytochrome P450, family 51, subfamily A, polypeptide 1||0.030|
|CCDC6||coiled-coil domain containing 6||0.017|
|FDFT1||farnesyl-diphosphate farnesyltransferase 1||0.015|
|SREBF2||sterol regulatory element binding transcription factor 2||0.013|