IMP
Process View
spindle assembly checkpoint
A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "spindle assembly checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 1.000 | Fly | |
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 1.000 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.989 | Yeast | |
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.977 | ||
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.972 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.908 | ||
| NDC80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.786 | ||
| CASC5 | cancer susceptibility candidate 5 | 0.773 | ||
| ZWINT | ZW10 interactor | 0.675 | ||
| ANAPC1 | anaphase promoting complex subunit 1 | 0.576 | ||
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.444 | ||
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.364 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.285 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.274 | ||
| NUF2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.214 | ||
| PLK1 | polo-like kinase 1 | 0.193 | ||
| TCP1 | t-complex 1 | 0.156 | ||
| ZNF207 | zinc finger protein 207 | 0.119 | ||
| SPC24 | SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.098 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.092 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.089 | ||
| DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.081 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.080 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.077 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.071 | ||
| H2AFX | H2A histone family, member X | 0.055 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.047 | ||
| PPP4C | protein phosphatase 4, catalytic subunit | 0.046 | ||
| NSL1 | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.045 | ||
| HIST1H4A | histone cluster 1, H4a | 0.044 | ||
| ATMIN | ATM interactor | 0.043 | ||
| CCNB1 | cyclin B1 | 0.042 | ||
| ANAPC7 | anaphase promoting complex subunit 7 | 0.041 | ||
| SPC25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.039 | ||
| AURKB | aurora kinase B | 0.039 | ||
| CBX5 | chromobox homolog 5 | 0.033 | ||
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.031 | ||
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.031 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.029 | ||
| AXIN2 | axin 2 | 0.028 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.027 | ||
| PRNP | prion protein | 0.027 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.026 | ||
| C14orf166 | chromosome 14 open reading frame 166 | 0.026 | ||
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.025 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.023 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.023 | ||
| ZW10 | ZW10, kinetochore associated, homolog (Drosophila) | 0.022 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.022 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.021 | ||
| CENPE | centromere protein E, 312kDa | 0.021 | Mouse | |
| SGOL2 | shugoshin-like 2 (S. pombe) | 0.021 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.020 | ||
| USP49 | ubiquitin specific peptidase 49 | 0.020 | ||
| BAG2 | BCL2-associated athanogene 2 | 0.018 | ||
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.018 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.018 | ||
| HIST1H4F | histone cluster 1, H4f | 0.018 | ||
| DEPDC1 | DEP domain containing 1 | 0.017 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.017 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.017 | ||
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.017 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.017 | ||
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.016 | Yeast | |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.016 | ||
| SERTAD4 | SERTA domain containing 4 | 0.016 | ||
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.016 | ||
| HIST1H1E | histone cluster 1, H1e | 0.016 | ||
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 0.015 | ||
| TOP3A | topoisomerase (DNA) III alpha | 0.015 | ||
| CBX1 | chromobox homolog 1 | 0.014 | ||
| DCLRE1C | DNA cross-link repair 1C | 0.014 | ||
| NBN | nibrin | 0.014 | ||
| C13orf34 | chromosome 13 open reading frame 34 | 0.014 | ||
| TTK | TTK protein kinase | 0.013 | Yeast | |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.013 | ||
| CCDC101 | coiled-coil domain containing 101 | 0.013 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.013 | ||
| CCNA2 | cyclin A2 | 0.013 | ||
| KDM5C | lysine (K)-specific demethylase 5C | 0.013 | ||
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 0.013 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.012 | ||
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.012 | ||
| HIST1H3C | histone cluster 1, H3c | 0.012 | Yeast | |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.012 | ||
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.012 | ||
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.012 | ||
| AURKA | aurora kinase A | 0.012 | ||
| HIST1H1B | histone cluster 1, H1b | 0.012 | ||
| BRCA2 | breast cancer 2, early onset | 0.012 | ||
| SGOL1 | shugoshin-like 1 (S. pombe) | 0.012 | ||
| MAD2L1BP | MAD2L1 binding protein | 0.012 | ||
| KIF18A | kinesin family member 18A | 0.011 | ||
| HIST1H2BB | histone cluster 1, H2bb | 0.011 | ||
| GPSM2 | G-protein signaling modulator 2 | 0.011 | ||
| NRD1 | nardilysin (N-arginine dibasic convertase) | 0.011 | ||
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.011 | Yeast | |
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.011 | ||
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.011 | ||
| HIST1H2AB | histone cluster 1, H2ab | 0.011 | ||
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.011 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.010 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.010 | ||
| KDM4A | lysine (K)-specific demethylase 4A | 0.010 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.010 | ||
| NKAP | NFKB activating protein | 0.010 | ||
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 | 0.010 | ||
| KIF14 | kinesin family member 14 | 0.010 | ||
| HIST1H3F | histone cluster 1, H3f | 0.010 |