IMP: Integrative Multi-species Prediction

Homo sapiens

2 genes annotated in human

syncytium formation by plasma membrane fusion

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "syncytium formation by plasma membrane fusion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "syncytium formation by plasma membrane fusion" (in gray)

Name	Description	Probability	Func Analog Organism
IQGAP1	IQ motif containing GTPase activating protein 1	0.975
GRB2	growth factor receptor-bound protein 2	0.972
ABI2	abl-interactor 2	0.970
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.904
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.673
PTK2	PTK2 protein tyrosine kinase 2	0.597
DOCK1	dedicator of cytokinesis 1	0.593	Fly
ALDOA	aldolase A, fructose-bisphosphate	0.519
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.459
HDAC4	histone deacetylase 4	0.449
EGFR	epidermal growth factor receptor	0.445
MSN	moesin	0.426
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.402
CAPNS1	calpain, small subunit 1	0.368
IRS1	insulin receptor substrate 1	0.360
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.359
DLG1	discs, large homolog 1 (Drosophila)	0.358
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.345
SH3KBP1	SH3-domain kinase binding protein 1	0.328
FN1	fibronectin 1	0.308
SH3BP2	SH3-domain binding protein 2	0.295
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.295
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.293
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.288
PGK1	phosphoglycerate kinase 1	0.284
GRB10	growth factor receptor-bound protein 10	0.281
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.264
IL2RG	interleukin 2 receptor, gamma	0.261
SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.252
AR	androgen receptor	0.250
LIMS1	LIM and senescent cell antigen-like domains 1	0.247
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.228
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.227
DPP4	dipeptidyl-peptidase 4	0.222
WIPF1	WAS/WASL interacting protein family, member 1	0.220
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.218
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.213	Fly
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.207	Fly
ELMO1	engulfment and cell motility 1	0.199	Fly
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.192
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.190
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.186
QKI	quaking homolog, KH domain RNA binding (mouse)	0.183
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.182
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.169
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.168
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.159
PXN	paxillin	0.159	Fly
KAT2B	K(lysine) acetyltransferase 2B	0.149
SIRT1	sirtuin 1	0.144
SH3RF1	SH3 domain containing ring finger 1	0.143
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.141
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.141
NCK1	NCK adaptor protein 1	0.140	Fly
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.135
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.134
CXCL11	chemokine (C-X-C motif) ligand 11	0.129
CTTN	cortactin	0.124
SPAG9	sperm associated antigen 9	0.124
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.121
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.120
NLRC4	NLR family, CARD domain containing 4	0.116
RIPK2	receptor-interacting serine-threonine kinase 2	0.115
COASY	CoA synthase	0.113
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.106
BIRC2	baculoviral IAP repeat containing 2	0.105
ZYX	zyxin	0.105
LRRK2	leucine-rich repeat kinase 2	0.104
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.104
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.102
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.101	Zebrafish
ANKFY1	ankyrin repeat and FYVE domain containing 1	0.101
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.100
STK10	serine/threonine kinase 10	0.099
SH3D19	SH3 domain containing 19	0.098
NCK2	NCK adaptor protein 2	0.097	Fly
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.095
HDAC9	histone deacetylase 9	0.094
IRS2	insulin receptor substrate 2	0.094
JAM3	junctional adhesion molecule 3	0.092	Zebrafish
JAK2	Janus kinase 2	0.091
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.091
SOS1	son of sevenless homolog 1 (Drosophila)	0.091
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.090
NCOA6	nuclear receptor coactivator 6	0.088
TPM4	tropomyosin 4	0.087
TNS1	tensin 1	0.086
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.086
CD44	CD44 molecule (Indian blood group)	0.084	Rat
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.083
MAP2K3	mitogen-activated protein kinase kinase 3	0.083
CD58	CD58 molecule	0.083
HCK	hemopoietic cell kinase	0.083
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	0.082
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.080
JAM2	junctional adhesion molecule 2	0.079	Zebrafish
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	0.079
LASS2	LAG1 homolog, ceramide synthase 2	0.078
NCOA2	nuclear receptor coactivator 2	0.078
MYL9	myosin, light chain 9, regulatory	0.077
NCF2	neutrophil cytosolic factor 2	0.075
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.075
IL4	interleukin 4	0.074	Mouse
RPTOR	regulatory associated protein of MTOR, complex 1	0.073
ABI1	abl-interactor 1	0.073
DEPTOR	DEP domain containing MTOR-interacting protein	0.071
CSK	c-src tyrosine kinase	0.069
SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like	0.069
ATP6V1D	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	0.069
MICALL1	MICAL-like 1	0.069
VCL	vinculin	0.068
CCL14	chemokine (C-C motif) ligand 14	0.068
LCP1	lymphocyte cytosolic protein 1 (L-plastin)	0.068
BCAR1	breast cancer anti-estrogen resistance 1	0.067
GAB1	GRB2-associated binding protein 1	0.067
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.066
MAPK8	mitogen-activated protein kinase 8	0.065
FOXO3	forkhead box O3	0.065	Fly
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.064
HOXA1	homeobox A1	0.064
INSR	insulin receptor	0.064	Fly
BIRC3	baculoviral IAP repeat containing 3	0.064
CAV1	caveolin 1, caveolae protein, 22kDa	0.063
PFN1	profilin 1	0.062
IGFBP3	insulin-like growth factor binding protein 3	0.062
IFI16	interferon, gamma-inducible protein 16	0.062
WASL	Wiskott-Aldrich syndrome-like	0.061	Fly
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.060
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.060
CAST	calpastatin	0.058
FLNB	filamin B, beta	0.058
PLCG1	phospholipase C, gamma 1	0.057
TCF4	transcription factor 4	0.056
PTRF	polymerase I and transcript release factor	0.056
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.054	Fly
SYK	spleen tyrosine kinase	0.054
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.054
GPI	glucose-6-phosphate isomerase	0.054
CHN2	chimerin (chimaerin) 2	0.054
NCKAP1	NCK-associated protein 1	0.054
FOXO1	forkhead box O1	0.053	Fly
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.052	Fly
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.052
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.051
RHOA	ras homolog gene family, member A	0.051
EFHD2	EF-hand domain family, member D2	0.050
RHOG	ras homolog gene family, member G (rho G)	0.050
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.050
CLIP1	CAP-GLY domain containing linker protein 1	0.050
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.050
PGAM1	phosphoglycerate mutase 1 (brain)	0.049
CLTB	clathrin, light chain B	0.049
CREB1	cAMP responsive element binding protein 1	0.049
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.048
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.048
IL4R	interleukin 4 receptor	0.048	Mouse
PICALM	phosphatidylinositol binding clathrin assembly protein	0.047
TLN1	talin 1	0.047
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.046
ACTA1	actin, alpha 1, skeletal muscle	0.046
TANK	TRAF family member-associated NFKB activator	0.045
BBS10	Bardet-Biedl syndrome 10	0.045
AKT1S1	AKT1 substrate 1 (proline-rich)	0.045
TNS4	tensin 4	0.045
MED31	mediator complex subunit 31	0.044
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.044
TRAF3	TNF receptor-associated factor 3	0.044
EP300	E1A binding protein p300	0.043
JAK1	Janus kinase 1	0.043
EZR	ezrin	0.043
FHL2	four and a half LIM domains 2	0.043
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.043
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.043
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.043
IFNGR1	interferon gamma receptor 1	0.042
AHNAK	AHNAK nucleoprotein	0.042
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.042
FGFR1	fibroblast growth factor receptor 1	0.042
PHF21A	PHD finger protein 21A	0.042
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.041
PRDM8	PR domain containing 8	0.041
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.041	Zebrafish
NRG1	neuregulin 1	0.041
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.040
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.040
NCOA1	nuclear receptor coactivator 1	0.040
TAGLN2	transgelin 2	0.040
IL13RA1	interleukin 13 receptor, alpha 1	0.040
WARS	tryptophanyl-tRNA synthetase	0.040
CXCL9	chemokine (C-X-C motif) ligand 9	0.040	Mouse
SH2B1	SH2B adaptor protein 1	0.040
SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	0.040
XIAP	X-linked inhibitor of apoptosis	0.039
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.039
GLIPR1	GLI pathogenesis-related 1	0.039
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.039
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.039
SLA	Src-like-adaptor	0.039
VCAM1	vascular cell adhesion molecule 1	0.039
STAT5A	signal transducer and activator of transcription 5A	0.039
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.038
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.038
LDHA	lactate dehydrogenase A	0.038
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.038
FOXL1	forkhead box L1	0.038
HK1	hexokinase 1	0.038
SUFU	suppressor of fused homolog (Drosophila)	0.038
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.037
RHOU	ras homolog gene family, member U	0.037
MEF2C	myocyte enhancer factor 2C	0.037	Fly
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.037
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.037
TRIB3	tribbles homolog 3 (Drosophila)	0.037
PTK6	PTK6 protein tyrosine kinase 6	0.036
SORBS2	sorbin and SH3 domain containing 2	0.036
VAV1	vav 1 guanine nucleotide exchange factor	0.036	Fly
UBD	ubiquitin D	0.036
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.036
GRAP2	GRB2-related adaptor protein 2	0.036
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.036
SH3RF3	SH3 domain containing ring finger 3	0.036
ARHGAP15	Rho GTPase activating protein 15	0.035
HIPK2	homeodomain interacting protein kinase 2	0.035
UBASH3B	ubiquitin associated and SH3 domain containing B	0.035
IRF1	interferon regulatory factor 1	0.035
ZNF331	zinc finger protein 331	0.035
WNK1	WNK lysine deficient protein kinase 1	0.035
PRKCA	protein kinase C, alpha	0.035
ARFIP2	ADP-ribosylation factor interacting protein 2	0.035
ELSPBP1	epididymal sperm binding protein 1	0.034
MEF2A	myocyte enhancer factor 2A	0.034	Fly
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.034
DOCK2	dedicator of cytokinesis 2	0.034	Fly
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.034
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.034
TRIM38	tripartite motif containing 38	0.034
CREBBP	CREB binding protein	0.034
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.034
EVI2A	ecotropic viral integration site 2A	0.034
TRAF1	TNF receptor-associated factor 1	0.034
LRMP	lymphoid-restricted membrane protein	0.033
IGF1R	insulin-like growth factor 1 receptor	0.033	Fly
ATM	ataxia telangiectasia mutated	0.033
FYB	FYN binding protein	0.033
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.033
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.033
PPP1R3F	protein phosphatase 1, regulatory (inhibitor) subunit 3F	0.033
MLF2	myeloid leukemia factor 2	0.033
MFSD1	major facilitator superfamily domain containing 1	0.033
PRDM1	PR domain containing 1, with ZNF domain	0.033
SYNJ1	synaptojanin 1	0.032
ELL	elongation factor RNA polymerase II	0.032
PDLIM7	PDZ and LIM domain 7 (enigma)	0.032
TNFAIP8	tumor necrosis factor, alpha-induced protein 8	0.032
SOD2	superoxide dismutase 2, mitochondrial	0.032
MBD1	methyl-CpG binding domain protein 1	0.032
EGF	epidermal growth factor	0.032
RICTOR	RPTOR independent companion of MTOR, complex 2	0.032
MAPT	microtubule-associated protein tau	0.032
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.032
RHEB	Ras homolog enriched in brain	0.032
WDR1	WD repeat domain 1	0.032
ANXA1	annexin A1	0.032
RIN2	Ras and Rab interactor 2	0.031
TFEC	transcription factor EC	0.031
STAT5B	signal transducer and activator of transcription 5B	0.031
ZNF426	zinc finger protein 426	0.031
CXCL10	chemokine (C-X-C motif) ligand 10	0.031	Mouse
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.031
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.031
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.031
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.031
CXCL13	chemokine (C-X-C motif) ligand 13	0.030
FYN	FYN oncogene related to SRC, FGR, YES	0.030
ARHGAP25	Rho GTPase activating protein 25	0.030
AHR	aryl hydrocarbon receptor	0.030
SDCBP	syndecan binding protein (syntenin)	0.030
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.030
TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.030
ELF4	E74-like factor 4 (ets domain transcription factor)	0.030
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.030
BCL2A1	BCL2-related protein A1	0.030
PRR5	proline rich 5 (renal)	0.030
SORBS3	sorbin and SH3 domain containing 3	0.029
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.029
ATXN1	ataxin 1	0.029
C19orf6	chromosome 19 open reading frame 6	0.029
RAP1B	RAP1B, member of RAS oncogene family	0.029
MYLK2	myosin light chain kinase 2	0.029
KIAA0174	KIAA0174	0.029
SRGN	serglycin	0.029
PRR5L	proline rich 5 like	0.029
WASF2	WAS protein family, member 2	0.029
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.029
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.029
IRS4	insulin receptor substrate 4	0.029
SQRDL	sulfide quinone reductase-like (yeast)	0.029
EIF4E	eukaryotic translation initiation factor 4E	0.029
CNN2	calponin 2	0.029
BICD1	bicaudal D homolog 1 (Drosophila)	0.029
MAP7D1	MAP7 domain containing 1	0.029
CSNK1A1L	casein kinase 1, alpha 1-like	0.029
PITX3	paired-like homeodomain 3	0.029
GBP2	guanylate binding protein 2, interferon-inducible	0.028
HIC1	hypermethylated in cancer 1	0.028
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.028
IGFBP5	insulin-like growth factor binding protein 5	0.028
LRP6	low density lipoprotein receptor-related protein 6	0.028
ZHX1	zinc fingers and homeoboxes 1	0.028
EHD1	EH-domain containing 1	0.028	Mouse
TRAF2	TNF receptor-associated factor 2	0.028
POM121	POM121 membrane glycoprotein	0.028
MAD2L1BP	MAD2L1 binding protein	0.028
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.028
CARD11	caspase recruitment domain family, member 11	0.028
ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	0.028
PLEK	pleckstrin	0.028
CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	0.028
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.027
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.027
CXCR3	chemokine (C-X-C motif) receptor 3	0.027
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.027
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.027
IGFBP4	insulin-like growth factor binding protein 4	0.027
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.027
MYOD1	myogenic differentiation 1	0.027
TNS3	tensin 3	0.027
CELF2	CUGBP, Elav-like family member 2	0.027
RNF149	ring finger protein 149	0.027
IL15	interleukin 15	0.027
NUMBL	numb homolog (Drosophila)-like	0.027
KDM6B	lysine (K)-specific demethylase 6B	0.027
IFNG	interferon, gamma	0.027
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.027
BLK	B lymphoid tyrosine kinase	0.027
BCL2L1	BCL2-like 1	0.027
GMFG	glia maturation factor, gamma	0.027
MAP2K7	mitogen-activated protein kinase kinase 7	0.027
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	0.026
BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	0.026
EMD	emerin	0.026
NIN	ninein (GSK3B interacting protein)	0.026
FAS	Fas (TNF receptor superfamily, member 6)	0.026
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.026
RPL3L	ribosomal protein L3-like	0.026
IDO1	indoleamine 2,3-dioxygenase 1	0.026
PAX7	paired box 7	0.026
FAM129A	family with sequence similarity 129, member A	0.026
GLI1	GLI family zinc finger 1	0.026
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.026
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.026
MYO1C	myosin IC	0.026
TBX1	T-box 1	0.026
CTSS	cathepsin S	0.026
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.026
LACTB	lactamase, beta	0.026
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.026
KYNU	kynureninase	0.025
DDR1	discoidin domain receptor tyrosine kinase 1	0.025
MDFI	MyoD family inhibitor	0.025
CISH	cytokine inducible SH2-containing protein	0.025
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.025
SWAP70	SWAP switching B-cell complex 70kDa subunit	0.025
MN1	meningioma (disrupted in balanced translocation) 1	0.025
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.025	Rat
EPAS1	endothelial PAS domain protein 1	0.025
GUCY1A3	guanylate cyclase 1, soluble, alpha 3	0.025
LDLR	low density lipoprotein receptor	0.025
UBQLN4	ubiquilin 4	0.025
CCL13	chemokine (C-C motif) ligand 13	0.025
CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10	0.025
TNK2	tyrosine kinase, non-receptor, 2	0.025
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.025
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.025
FHOD1	formin homology 2 domain containing 1	0.025
MYBPH	myosin binding protein H	0.025
HDAC6	histone deacetylase 6	0.025
FLNA	filamin A, alpha	0.025
HNF1A	HNF1 homeobox A	0.025
MYOF	myoferlin	0.025
GAS7	growth arrest-specific 7	0.025
MAP2K4	mitogen-activated protein kinase kinase 4	0.025
TRIM43	tripartite motif containing 43	0.024
CAPZA1	capping protein (actin filament) muscle Z-line, alpha 1	0.024
COL5A3	collagen, type V, alpha 3	0.024
FOXB1	forkhead box B1	0.024
POFUT1	protein O-fucosyltransferase 1	0.024
BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	0.024
PLEKHB2	pleckstrin homology domain containing, family B (evectins) member 2	0.024
CARD16	caspase recruitment domain family, member 16	0.024
CLIC1	chloride intracellular channel 1	0.024
COX8A	cytochrome c oxidase subunit VIIIA (ubiquitous)	0.024
MIF4GD	MIF4G domain containing	0.024
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.024
HES1	hairy and enhancer of split 1, (Drosophila)	0.024
CCL8	chemokine (C-C motif) ligand 8	0.024
TNNI1	troponin I type 1 (skeletal, slow)	0.024
ANXA5	annexin A5	0.024
NOD2	nucleotide-binding oligomerization domain containing 2	0.024
COL6A3	collagen, type VI, alpha 3	0.024
IL13	interleukin 13	0.024
NRP2	neuropilin 2	0.024
CD248	CD248 molecule, endosialin	0.024
RNF17	ring finger protein 17	0.024
CD200	CD200 molecule	0.024
SIRT2	sirtuin 2	0.024
CD40	CD40 molecule, TNF receptor superfamily member 5	0.024
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.024
BTRC	beta-transducin repeat containing	0.024
ENO1	enolase 1, (alpha)	0.024
OLFML2A	olfactomedin-like 2A	0.024
GRB14	growth factor receptor-bound protein 14	0.024
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.024
TGFA	transforming growth factor, alpha	0.024
RIN1	Ras and Rab interactor 1	0.024
DLGAP4	discs, large (Drosophila) homolog-associated protein 4	0.023
NPAS1	neuronal PAS domain protein 1	0.023
PNPLA3	patatin-like phospholipase domain containing 3	0.023
SLC31A2	solute carrier family 31 (copper transporters), member 2	0.023
GLRX	glutaredoxin (thioltransferase)	0.023
DOK4	docking protein 4	0.023
SAMD9	sterile alpha motif domain containing 9	0.023
CDX2	caudal type homeobox 2	0.023
CD274	CD274 molecule	0.023
FURIN	furin (paired basic amino acid cleaving enzyme)	0.023
UPP1	uridine phosphorylase 1	0.023
UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	0.023
STK17B	serine/threonine kinase 17b	0.023
CSF3	colony stimulating factor 3 (granulocyte)	0.023
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.023
AXIN1	axin 1	0.023
SIX1	SIX homeobox 1	0.023
DEFA1	defensin, alpha 1	0.023
SMAD7	SMAD family member 7	0.023
STX12	syntaxin 12	0.023
RAB27A	RAB27A, member RAS oncogene family	0.023
ACTC1	actin, alpha, cardiac muscle 1	0.023
TLX2	T-cell leukemia homeobox 2	0.023
JUP	junction plakoglobin	0.023
HOXD12	homeobox D12	0.023
POU4F3	POU class 4 homeobox 3	0.023
KIAA1539	KIAA1539	0.023
ACHE	acetylcholinesterase	0.023
KIAA1217	KIAA1217	0.023
SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	0.023
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.023
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.023
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.023
DOK6	docking protein 6	0.023
JAG1	jagged 1	0.023
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.023
VASP	vasodilator-stimulated phosphoprotein	0.023
NEUROG3	neurogenin 3	0.023
TSPAN7	tetraspanin 7	0.023
EPOR	erythropoietin receptor	0.023
VCAN	versican	0.023
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.023
IRF8	interferon regulatory factor 8	0.023
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.023
ARHGAP31	Rho GTPase activating protein 31	0.023
PDLIM1	PDZ and LIM domain 1	0.023
EPHA2	EPH receptor A2	0.023
USP22	ubiquitin specific peptidase 22	0.023
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	0.023
SCAF1	SR-related CTD-associated factor 1	0.023
ADAM10	ADAM metallopeptidase domain 10	0.023
EFNB2	ephrin-B2	0.022
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.022
MYLK	myosin light chain kinase	0.022
PDPK1	3-phosphoinositide dependent protein kinase-1	0.022
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.022
HBZ	hemoglobin, zeta	0.022
OCRL	oculocerebrorenal syndrome of Lowe	0.022
CUX1	cut-like homeobox 1	0.022
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.022
CKM	creatine kinase, muscle	0.022
RHEBL1	Ras homolog enriched in brain like 1	0.022
LAMA4	laminin, alpha 4	0.022
SOX8	SRY (sex determining region Y)-box 8	0.022
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.022
CLEC2B	C-type lectin domain family 2, member B	0.022
TUBB6	tubulin, beta 6	0.022
AKAP13	A kinase (PRKA) anchor protein 13	0.022
FGF3	fibroblast growth factor 3	0.022
ZNF764	zinc finger protein 764	0.022
HOXD11	homeobox D11	0.022
REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	0.022
IGFBP6	insulin-like growth factor binding protein 6	0.022
GBP1	guanylate binding protein 1, interferon-inducible	0.022
MEF2D	myocyte enhancer factor 2D	0.022	Fly
FOXO4	forkhead box O4	0.022
DLG5	discs, large homolog 5 (Drosophila)	0.022
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.022
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.022
SELPLG	selectin P ligand	0.022
CRLF3	cytokine receptor-like factor 3	0.022
AIM1	absent in melanoma 1	0.022
SH2B2	SH2B adaptor protein 2	0.022
TOM1	target of myb1 (chicken)	0.022
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.022
STK17A	serine/threonine kinase 17a	0.022
ADAMDEC1	ADAM-like, decysin 1	0.022
LIMK1	LIM domain kinase 1	0.022
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.022
PEX26	peroxisomal biogenesis factor 26	0.022
MSC	musculin	0.022
COL1A2	collagen, type I, alpha 2	0.021
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.021
YARS	tyrosyl-tRNA synthetase	0.021
TM2D2	TM2 domain containing 2	0.021
LDB2	LIM domain binding 2	0.021
LBX1	ladybird homeobox 1	0.021	Fly
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.021
MAP1B	microtubule-associated protein 1B	0.021
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.021
CSNK1D	casein kinase 1, delta	0.021
GBX2	gastrulation brain homeobox 2	0.021
CIB1	calcium and integrin binding 1 (calmyrin)	0.021
ZNF267	zinc finger protein 267	0.021
TNNT3	troponin T type 3 (skeletal, fast)	0.021
ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	0.021
APOL1	apolipoprotein L, 1	0.021
SPATA24	spermatogenesis associated 24	0.021
SPEG	SPEG complex locus	0.021
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.021
TUBA1C	tubulin, alpha 1c	0.021
ARMCX2	armadillo repeat containing, X-linked 2	0.021
OBFC2A	oligonucleotide/oligosaccharide-binding fold containing 2A	0.021
VGLL3	vestigial like 3 (Drosophila)	0.021
FGF8	fibroblast growth factor 8 (androgen-induced)	0.021
LHFP	lipoma HMGIC fusion partner	0.021
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.021
PALLD	palladin, cytoskeletal associated protein	0.021
TRIOBP	TRIO and F-actin binding protein	0.021
TLR2	toll-like receptor 2	0.021
KLF5	Kruppel-like factor 5 (intestinal)	0.021
CCL22	chemokine (C-C motif) ligand 22	0.021
LTBP2	latent transforming growth factor beta binding protein 2	0.021
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.021
VSX1	visual system homeobox 1	0.021
PLSCR3	phospholipid scramblase 3	0.021
TP73	tumor protein p73	0.021
COL4A2	collagen, type IV, alpha 2	0.021
CYTH1	cytohesin 1	0.021
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.021
CAV2	caveolin 2	0.021
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.021
SPRY4	sprouty homolog 4 (Drosophila)	0.021
EVX1	even-skipped homeobox 1	0.021
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.020
SPRR2A	small proline-rich protein 2A	0.020
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.020
SETBP1	SET binding protein 1	0.020
PCDHB11	protocadherin beta 11	0.020
MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1	0.020
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.020
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.020
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.020
EEF1G	eukaryotic translation elongation factor 1 gamma	0.020
HAND2	heart and neural crest derivatives expressed 2	0.020
C16orf70	chromosome 16 open reading frame 70	0.020
ALX3	ALX homeobox 3	0.020
FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	0.020
MYL12B	myosin, light chain 12B, regulatory	0.020
RTN4	reticulon 4	0.020
CD97	CD97 molecule	0.020
NBL1	neuroblastoma, suppression of tumorigenicity 1	0.020
TRIM22	tripartite motif containing 22	0.020
COTL1	coactosin-like 1 (Dictyostelium)	0.020
CORO1C	coronin, actin binding protein, 1C	0.020
CARD6	caspase recruitment domain family, member 6	0.020
CLCF1	cardiotrophin-like cytokine factor 1	0.020
SEMA6C	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.020
GPR20	G protein-coupled receptor 20	0.020
ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	0.020
SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	0.020
MED25	mediator complex subunit 25	0.020
ACTN3	actinin, alpha 3	0.020
TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	0.020
ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8	0.020
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.020
LY75	lymphocyte antigen 75	0.020
AIM2	absent in melanoma 2	0.020
S100A10	S100 calcium binding protein A10	0.020
SESN2	sestrin 2	0.020
ACTN1	actinin, alpha 1	0.020
HSPB3	heat shock 27kDa protein 3	0.020
DRD4	dopamine receptor D4	0.020
GDNF	glial cell derived neurotrophic factor	0.020
CD83	CD83 molecule	0.020
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.020
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.020
VAV2	vav 2 guanine nucleotide exchange factor	0.020	Fly
ZNF556	zinc finger protein 556	0.020
TLX3	T-cell leukemia homeobox 3	0.020
SIAH2	seven in absentia homolog 2 (Drosophila)	0.020
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.020
PTK7	PTK7 protein tyrosine kinase 7	0.020
PLAC8	placenta-specific 8	0.020
IL1A	interleukin 1, alpha	0.020
ALK	anaplastic lymphoma receptor tyrosine kinase	0.020
RHBDF2	rhomboid 5 homolog 2 (Drosophila)	0.020
RHOC	ras homolog gene family, member C	0.020
ZFPM1	zinc finger protein, multitype 1	0.020
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.020
C9orf142	chromosome 9 open reading frame 142	0.020
GPR135	G protein-coupled receptor 135	0.020
ATP13A3	ATPase type 13A3	0.020
DENND5A	DENN/MADD domain containing 5A	0.020
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.020
MAPK11	mitogen-activated protein kinase 11	0.020
KLF13	Kruppel-like factor 13	0.020
OLFML3	olfactomedin-like 3	0.020
LASP1	LIM and SH3 protein 1	0.020
IRF2	interferon regulatory factor 2	0.020
DLX2	distal-less homeobox 2	0.020
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.020
ZHX2	zinc fingers and homeoboxes 2	0.020
GPR161	G protein-coupled receptor 161	0.020
CHSY1	chondroitin sulfate synthase 1	0.020
PITX2	paired-like homeodomain 2	0.020	Mouse
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.020
LRRC8C	leucine rich repeat containing 8 family, member C	0.020
TPBG	trophoblast glycoprotein	0.020
CYTH3	cytohesin 3	0.019
OSMR	oncostatin M receptor	0.019
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.019
FOXK1	forkhead box K1	0.019
HDAC5	histone deacetylase 5	0.019
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.019
FBP2	fructose-1,6-bisphosphatase 2	0.019
LPAR4	lysophosphatidic acid receptor 4	0.019
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.019
CYTIP	cytohesin 1 interacting protein	0.019
ANKRD7	ankyrin repeat domain 7	0.019
EGFL6	EGF-like-domain, multiple 6	0.019
CXCR4	chemokine (C-X-C motif) receptor 4	0.019
ZNF828	zinc finger protein 828	0.019
HPCAL1	hippocalcin-like 1	0.019
DHX34	DEAH (Asp-Glu-Ala-His) box polypeptide 34	0.019
TMEM44	transmembrane protein 44	0.019
RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	0.019
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.019
BOC	Boc homolog (mouse)	0.019
SRL	sarcalumenin	0.019
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.019
KCTD9	potassium channel tetramerisation domain containing 9	0.019
C19orf26	chromosome 19 open reading frame 26	0.019
HGFAC	HGF activator	0.019
GPM6B	glycoprotein M6B	0.019
CRCP	CGRP receptor component	0.019
CRY1	cryptochrome 1 (photolyase-like)	0.019
ACTN2	actinin, alpha 2	0.019
DPYD	dihydropyrimidine dehydrogenase	0.019
RAB5C	RAB5C, member RAS oncogene family	0.019
PLAGL1	pleiomorphic adenoma gene-like 1	0.019
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.019
BBC3	BCL2 binding component 3	0.019
FOXD3	forkhead box D3	0.019
COL12A1	collagen, type XII, alpha 1	0.019
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.019
CORO1A	coronin, actin binding protein, 1A	0.019
FLI1	Friend leukemia virus integration 1	0.019
FKBP1A	FK506 binding protein 1A, 12kDa	0.019
CLTCL1	clathrin, heavy chain-like 1	0.019
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.019
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.019
CLIC2	chloride intracellular channel 2	0.019
ANKRD35	ankyrin repeat domain 35	0.019
TCAP	titin-cap (telethonin)	0.019
OTX2	orthodenticle homeobox 2	0.019
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.019
UNKL	unkempt homolog (Drosophila)-like	0.019
MYBPC2	myosin binding protein C, fast type	0.019
PLEKHA4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.019
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.019
EMX1	empty spiracles homeobox 1	0.019
NCKIPSD	NCK interacting protein with SH3 domain	0.019
NOD1	nucleotide-binding oligomerization domain containing 1	0.019
GSC	goosecoid homeobox	0.019
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.019
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.019
CACNG1	calcium channel, voltage-dependent, gamma subunit 1	0.019
HYAL4	hyaluronoglucosaminidase 4	0.019
TOLLIP	toll interacting protein	0.019
MAPK7	mitogen-activated protein kinase 7	0.019
MTFP1	mitochondrial fission process 1	0.019
IL12RB2	interleukin 12 receptor, beta 2	0.019
POMC	proopiomelanocortin	0.019
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.019
ACTN4	actinin, alpha 4	0.019
WNT3	wingless-type MMTV integration site family, member 3	0.019
SPTB	spectrin, beta, erythrocytic	0.019
PHACTR3	phosphatase and actin regulator 3	0.019
LITAF	lipopolysaccharide-induced TNF factor	0.019
NMI	N-myc (and STAT) interactor	0.019
ARSB	arylsulfatase B	0.019
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.019
BNC2	basonuclin 2	0.019
CHMP7	CHMP family, member 7	0.019
GLS	glutaminase	0.019
PAX8	paired box 8	0.019
DEGS1	degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)	0.019
CD59	CD59 molecule, complement regulatory protein	0.019
HBQ1	hemoglobin, theta 1	0.019
RAB31	RAB31, member RAS oncogene family	0.019
POU4F1	POU class 4 homeobox 1	0.019
IL1R1	interleukin 1 receptor, type I	0.019
UGCG	UDP-glucose ceramide glucosyltransferase	0.019
PGM5	phosphoglucomutase 5	0.019
MAP2K6	mitogen-activated protein kinase kinase 6	0.019
BCL10	B-cell CLL/lymphoma 10	0.019
RIT1	Ras-like without CAAX 1	0.019
NFE2L3	nuclear factor (erythroid-derived 2)-like 3	0.019
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.019
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.019
HOXC5	homeobox C5	0.019
ANK1	ankyrin 1, erythrocytic	0.019
NKX6-1	NK6 homeobox 1	0.019
SCG5	secretogranin V (7B2 protein)	0.019
KBTBD5	kelch repeat and BTB (POZ) domain containing 5	0.019
LOXL1	lysyl oxidase-like 1	0.019
FADS3	fatty acid desaturase 3	0.019
IL10RB	interleukin 10 receptor, beta	0.019
OR10H2	olfactory receptor, family 10, subfamily H, member 2	0.019
HIPK3	homeodomain interacting protein kinase 3	0.019
VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)	0.019
GTPBP5	GTP binding protein 5 (putative)	0.019
CRX	cone-rod homeobox	0.019
MLNR	motilin receptor	0.019
GHR	growth hormone receptor	0.019
RRAGC	Ras-related GTP binding C	0.019
NKX2-8	NK2 homeobox 8	0.019
SFN	stratifin	0.018
PDE4B	phosphodiesterase 4B, cAMP-specific	0.018
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.018
CTSC	cathepsin C	0.018
KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8	0.018
BTN3A2	butyrophilin, subfamily 3, member A2	0.018
ADCY7	adenylate cyclase 7	0.018
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.018
ERO1L	ERO1-like (S. cerevisiae)	0.018
HOXA10	homeobox A10	0.018
IFNB1	interferon, beta 1, fibroblast	0.018
PHKG1	phosphorylase kinase, gamma 1 (muscle)	0.018
C3orf10	chromosome 3 open reading frame 10	0.018
MYOZ2	myozenin 2	0.018
RAPSN	receptor-associated protein of the synapse	0.018
SDF2	stromal cell-derived factor 2	0.018
RNF19B	ring finger protein 19B	0.018