3 genes annotated in humanMulti-species View
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway"
|Name||Description||Probability||Func Analog Organism|
|HLA-C||major histocompatibility complex, class I, C||0.998|
|HLA-B||major histocompatibility complex, class I, B||0.997|
|HLA-A||major histocompatibility complex, class I, A||0.995|
|HLA-G||major histocompatibility complex, class I, G||0.968||Human|
|HLA-E||major histocompatibility complex, class I, E||0.958||Human|
|HLA-F||major histocompatibility complex, class I, F||0.901||Human|
|TAP1||transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)||0.887|
|TAPBP||TAP binding protein (tapasin)||0.721|
|PSMB8||proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)||0.050|
|IFITM2||interferon induced transmembrane protein 2 (1-8D)||0.012|
|TAP2||transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)||0.012||Mouse|