IMP
Process View
activation of mapkkk activity
Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "activation of mapkkk activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 1.000 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.954 | ||
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.942 | ||
| RPS14 | ribosomal protein S14 | 0.787 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.758 | ||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.622 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.499 | ||
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 0.316 | ||
| SH3RF3 | SH3 domain containing ring finger 3 | 0.311 | ||
| MIDN | midnolin | 0.306 | ||
| CRIPAK | cysteine-rich PAK1 inhibitor | 0.265 | ||
| RPS11 | ribosomal protein S11 | 0.225 | ||
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.161 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.151 | ||
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.130 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.105 | ||
| RPS28 | ribosomal protein S28 | 0.087 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.078 | ||
| RHOU | ras homolog gene family, member U | 0.072 | ||
| BAIAP2 | BAI1-associated protein 2 | 0.072 | ||
| RPS27 | ribosomal protein S27 | 0.069 | ||
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.064 | ||
| TRIP10 | thyroid hormone receptor interactor 10 | 0.063 | ||
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.063 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.055 | ||
| RPS15A | ribosomal protein S15a | 0.054 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.053 | ||
| SORBS2 | sorbin and SH3 domain containing 2 | 0.052 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.045 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.044 | ||
| RPS27A | ribosomal protein S27a | 0.040 | ||
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.035 | ||
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.030 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.030 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.027 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.026 | ||
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 | 0.021 | ||
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.017 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.017 | ||
| CHN2 | chimerin (chimaerin) 2 | 0.016 | ||
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.014 | ||
| CCND3 | cyclin D3 | 0.014 | ||
| OCRL | oculocerebrorenal syndrome of Lowe | 0.013 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.012 | Yeast | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.012 | ||
| DCTN2 | dynactin 2 (p50) | 0.012 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.012 | ||
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.012 |