IMP: Integrative Multi-species Prediction

Homo sapiens

11 genes annotated in human

Multi-species View

single fertilization

GO:0007338

The union of male and female gametes to form a zygote.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "single fertilization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "single fertilization" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.997	Worm
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.995	Worm
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.974	Mouse
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.974	Mouse
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.896	Worm
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.882	Worm
TCP1	t-complex 1	0.865	Mouse
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.822	Mouse
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	0.550
CKAP5	cytoskeleton associated protein 5	0.440	Worm Fly
PRC1	protein regulator of cytokinesis 1	0.416
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.398
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.397
OCRL	oculocerebrorenal syndrome of Lowe	0.393
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.344	Worm
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.333
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.282	Worm
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.236
SNRPG	small nuclear ribonucleoprotein polypeptide G	0.205
EIF4A3	eukaryotic translation initiation factor 4A3	0.178
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.140	Worm
RAN	RAN, member RAS oncogene family	0.132
DYNLL1	dynein, light chain, LC8-type 1	0.123	Worm
KIF23	kinesin family member 23	0.115	Worm
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.109	Mouse
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.108
PFDN2	prefoldin subunit 2	0.108	Worm
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.106
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.106
DYNLT3	dynein, light chain, Tctex-type 3	0.104
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.089
CAPNS1	calpain, small subunit 1	0.087
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.087
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.086
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.084
AURKA	aurora kinase A	0.076
CCNB2	cyclin B2	0.074
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.073	Worm
TRIP6	thyroid hormone receptor interactor 6	0.071
PPP4C	protein phosphatase 4, catalytic subunit	0.068
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.068
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.064
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.063
UBAP2L	ubiquitin associated protein 2-like	0.062
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.062
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.058
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.056
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.053
POMP	proteasome maturation protein	0.051
RBM14	RNA binding motif protein 14	0.049
CD81	CD81 molecule	0.049	Human
RACGAP1	Rac GTPase activating protein 1	0.047
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.046
SNAP25	synaptosomal-associated protein, 25kDa	0.046
CAPRIN1	cell cycle associated protein 1	0.045
SSRP1	structure specific recognition protein 1	0.045
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.044
CD63	CD63 molecule	0.043
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.042
CCNB1	cyclin B1	0.041
TACC3	transforming, acidic coiled-coil containing protein 3	0.041	Fly
CD9	CD9 molecule	0.038
FLNA	filamin A, alpha	0.038
CCNA2	cyclin A2	0.038
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.038
CDK2	cyclin-dependent kinase 2	0.037
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.036
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.036	Mouse
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.036
RARS	arginyl-tRNA synthetase	0.035
TXN	thioredoxin	0.035
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.033
TUBA3E	tubulin, alpha 3e	0.033
MPRIP	myosin phosphatase Rho interacting protein	0.032
GAS2L3	growth arrest-specific 2 like 3	0.030
VBP1	von Hippel-Lindau binding protein 1	0.029	Worm
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.029	Worm
DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	0.029
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.029
POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	0.028
KARS	lysyl-tRNA synthetase	0.028
C14orf1	chromosome 14 open reading frame 1	0.026
CCT2	chaperonin containing TCP1, subunit 2 (beta)	0.026	Mouse
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.025
ERH	enhancer of rudimentary homolog (Drosophila)	0.025
TDRD7	tudor domain containing 7	0.025
SEC61G	Sec61 gamma subunit	0.024
PARP1	poly (ADP-ribose) polymerase 1	0.024
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.024
EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)	0.024
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.022
CKS2	CDC28 protein kinase regulatory subunit 2	0.022
WDR77	WD repeat domain 77	0.022
NCL	nucleolin	0.022
HDAC4	histone deacetylase 4	0.021
CTPS	CTP synthase	0.021
HSPA8	heat shock 70kDa protein 8	0.021
NCOA2	nuclear receptor coactivator 2	0.021
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.020
ACTR10	actin-related protein 10 homolog (S. cerevisiae)	0.020
PRDX1	peroxiredoxin 1	0.020
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.020	Worm
SNRPE	small nuclear ribonucleoprotein polypeptide E	0.019
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.019
TUBB	tubulin, beta	0.019
STIP1	stress-induced-phosphoprotein 1	0.019
SET	SET nuclear oncogene	0.018
CHRAC1	chromatin accessibility complex 1	0.018
MARK2	MAP/microtubule affinity-regulating kinase 2	0.018
NUP93	nucleoporin 93kDa	0.018
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.018
TUBA1B	tubulin, alpha 1b	0.018
AURKB	aurora kinase B	0.017
RIPK3	receptor-interacting serine-threonine kinase 3	0.017
TRIM37	tripartite motif containing 37	0.017
C15orf63	chromosome 15 open reading frame 63	0.017
CBFB	core-binding factor, beta subunit	0.017
SFN	stratifin	0.017
GOLM1	golgi membrane protein 1	0.016
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.016
RBM12	RNA binding motif protein 12	0.016
SRSF9	serine/arginine-rich splicing factor 9	0.016
DICER1	dicer 1, ribonuclease type III	0.015
C3orf34	chromosome 3 open reading frame 34	0.015
MRPL18	mitochondrial ribosomal protein L18	0.015
KIAA1279	KIAA1279	0.015
PEF1	penta-EF-hand domain containing 1	0.015
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.015
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.015
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.015
BMS1	BMS1 homolog, ribosome assembly protein (yeast)	0.015
SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)	0.014
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.014
CDCA8	cell division cycle associated 8	0.014
RPL26L1	ribosomal protein L26-like 1	0.014
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.014
UBAP2	ubiquitin associated protein 2	0.013	Human
MEIS1	Meis homeobox 1	0.013
HOXA10	homeobox A10	0.013
ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)	0.013
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.013
PTTG1	pituitary tumor-transforming 1	0.013
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.013
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.013
HJURP	Holliday junction recognition protein	0.012
DCAF7	DDB1 and CUL4 associated factor 7	0.012
CENPF	centromere protein F, 350/400kDa (mitosin)	0.012
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.012
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.012
STK24	serine/threonine kinase 24	0.012
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.012
KIF11	kinesin family member 11	0.012
SRSF3	serine/arginine-rich splicing factor 3	0.012
WDR20	WD repeat domain 20	0.012
RCC1	regulator of chromosome condensation 1	0.011
RNF14	ring finger protein 14	0.011
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.011
BICD2	bicaudal D homolog 2 (Drosophila)	0.011
EIF4E	eukaryotic translation initiation factor 4E	0.011
RBM8A	RNA binding motif protein 8A	0.011
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.011
MAPK15	mitogen-activated protein kinase 15	0.011
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.011
PRRC2A	proline-rich coiled-coil 2A	0.011
DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	0.010	Worm
RUNX1	runt-related transcription factor 1	0.010
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.010
TSPAN4	tetraspanin 4	0.010
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.010
SUB1	SUB1 homolog (S. cerevisiae)	0.010
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.010