IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

Multi-species View

positive regulation of transcription from rna polymerase ii promoter involved in heart development

GO:1901228

Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of transcription from rna polymerase ii promoter involved in heart development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of transcription from rna polymerase ii promoter involved in heart development" (in gray)

Name	Description	Probability	Func Analog Organism
SRF	serum response factor (c-fos serum response element-binding transcription factor)	1.000
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.999
MKL1	megakaryoblastic leukemia (translocation) 1	0.984	Human
BTF3	basic transcription factor 3	0.971
MYOG	myogenin (myogenic factor 4)	0.930
MYOD1	myogenic differentiation 1	0.904
MYOCD	myocardin	0.861
SMAD1	SMAD family member 1	0.853
GATA4	GATA binding protein 4	0.748
FUNDC2	FUN14 domain containing 2	0.558
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.455
NCOR2	nuclear receptor corepressor 2	0.455
MKL2	MKL/myocardin-like 2	0.367	Human
NSA2	NSA2 ribosome biogenesis homolog (S. cerevisiae)	0.270
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.152
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.144
RPL36AL	ribosomal protein L36a-like	0.128
RPL34	ribosomal protein L34	0.079
SMAD7	SMAD family member 7	0.070
TBX1	T-box 1	0.054	Human
RPL36A	ribosomal protein L36a	0.048
SOX18	SRY (sex determining region Y)-box 18	0.045
TBX5	T-box 5	0.044	Human
SMAD6	SMAD family member 6	0.043
PML	promyelocytic leukemia	0.042
AR	androgen receptor	0.040
GATA5	GATA binding protein 5	0.039
FOXF1	forkhead box F1	0.039
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.037
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.034
MSX1	msh homeobox 1	0.033
PYY	peptide YY	0.033
FGF8	fibroblast growth factor 8 (androgen-induced)	0.031
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.029
SMAD4	SMAD family member 4	0.027
ZHX1	zinc fingers and homeoboxes 1	0.027
NSF	N-ethylmaleimide-sensitive factor	0.027
ARL15	ADP-ribosylation factor-like 15	0.027
LBX1	ladybird homeobox 1	0.026
IL2RB	interleukin 2 receptor, beta	0.026
RPL26	ribosomal protein L26	0.023
RPL17	ribosomal protein L17	0.022
HOXD12	homeobox D12	0.021
COL13A1	collagen, type XIII, alpha 1	0.021
HOXD9	homeobox D9	0.021
COL2A1	collagen, type II, alpha 1	0.020
FGF3	fibroblast growth factor 3	0.019
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.019
ASCC2	activating signal cointegrator 1 complex subunit 2	0.019
CXCR6	chemokine (C-X-C motif) receptor 6	0.018
BANP	BTG3 associated nuclear protein	0.017
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.017
SOX1	SRY (sex determining region Y)-box 1	0.017
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.017
FGF18	fibroblast growth factor 18	0.017
PABPC3	poly(A) binding protein, cytoplasmic 3	0.017
HOXB13	homeobox B13	0.017
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.017
PPARA	peroxisome proliferator-activated receptor alpha	0.016
HOXC11	homeobox C11	0.016
GNLY	granulysin	0.016
USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.016
RPL35A	ribosomal protein L35a	0.016
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.016
VAX2	ventral anterior homeobox 2	0.016
FOXF2	forkhead box F2	0.016
EGR1	early growth response 1	0.016
NFYA	nuclear transcription factor Y, alpha	0.015
SIX2	SIX homeobox 2	0.015
LTK	leukocyte receptor tyrosine kinase	0.015
YAP1	Yes-associated protein 1	0.015
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.015
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.015
ZNF33B	zinc finger protein 33B	0.015
ELK1	ELK1, member of ETS oncogene family	0.015
DLL4	delta-like 4 (Drosophila)	0.015
NKX2-8	NK2 homeobox 8	0.014
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.014
COMP	cartilage oligomeric matrix protein	0.014
CSPG4	chondroitin sulfate proteoglycan 4	0.014
GATA2	GATA binding protein 2	0.014
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.014
CD7	CD7 molecule	0.014
EEF1B2	eukaryotic translation elongation factor 1 beta 2	0.014
HOXA11	homeobox A11	0.014
GTF2I	general transcription factor IIi	0.014
PFDN5	prefoldin subunit 5	0.014
RPL41	ribosomal protein L41	0.014
PGR	progesterone receptor	0.013
GNG11	guanine nucleotide binding protein (G protein), gamma 11	0.013
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
HOXC8	homeobox C8	0.013
DLX4	distal-less homeobox 4	0.013
IRX5	iroquois homeobox 5	0.013
FOXL1	forkhead box L1	0.013
GATA3	GATA binding protein 3	0.013
HOXD11	homeobox D11	0.013
TBX2	T-box 2	0.013	Human
KLHL35	kelch-like 35 (Drosophila)	0.013
CHRDL2	chordin-like 2	0.013
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.013
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.013
HES2	hairy and enhancer of split 2 (Drosophila)	0.013
SIM2	single-minded homolog 2 (Drosophila)	0.013
SAT1	spermidine/spermine N1-acetyltransferase 1	0.012
PAX3	paired box 3	0.012
FASLG	Fas ligand (TNF superfamily, member 6)	0.012
MAST4	microtubule associated serine/threonine kinase family member 4	0.012
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.012
HOXD13	homeobox D13	0.012
IGBP1	immunoglobulin (CD79A) binding protein 1	0.012
FOXD2	forkhead box D2	0.012
TLX1	T-cell leukemia homeobox 1	0.012
WNT1	wingless-type MMTV integration site family, member 1	0.012
RPS6	ribosomal protein S6	0.012
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.012
CXCR3	chemokine (C-X-C motif) receptor 3	0.012
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.012
CALCA	calcitonin-related polypeptide alpha	0.012
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.012
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.012
SCARF2	scavenger receptor class F, member 2	0.011
RARA	retinoic acid receptor, alpha	0.011
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.011
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.011
PRDM8	PR domain containing 8	0.011
NOVA2	neuro-oncological ventral antigen 2	0.011
MAPK7	mitogen-activated protein kinase 7	0.011
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.011
IRX4	iroquois homeobox 4	0.011
CHRD	chordin	0.011
OTOP2	otopetrin 2	0.011
RUNX1	runt-related transcription factor 1	0.011
FLT4	fms-related tyrosine kinase 4	0.011
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
CNN1	calponin 1, basic, smooth muscle	0.011
OTP	orthopedia homeobox	0.011
ATOH8	atonal homolog 8 (Drosophila)	0.011
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.011
POU3F1	POU class 3 homeobox 1	0.011
PAX2	paired box 2	0.010
RAX	retina and anterior neural fold homeobox	0.010
OAF	OAF homolog (Drosophila)	0.010
CRLF1	cytokine receptor-like factor 1	0.010
CLCF1	cardiotrophin-like cytokine factor 1	0.010
HOXB5	homeobox B5	0.010
EVX1	even-skipped homeobox 1	0.010
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.010
FOXN4	forkhead box N4	0.010
GJC2	gap junction protein, gamma 2, 47kDa	0.010
FOXA2	forkhead box A2	0.010
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.010
GMEB1	glucocorticoid modulatory element binding protein 1	0.010
NKX2-1	NK2 homeobox 1	0.010