IMP: Integrative Multi-species Prediction

Homo sapiens

404 genes annotated in human

purine ribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

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Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "purine ribonucleotide catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	1.000	Human Mouse Rat Worm Fly
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	1.000
RAB5A	RAB5A, member RAS oncogene family	1.000
SH3KBP1	SH3-domain kinase binding protein 1	0.998
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.997	Human Yeast Mouse Worm Fly
OCRL	oculocerebrorenal syndrome of Lowe	0.996
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.996
ARRB2	arrestin, beta 2	0.995	Human Rat
PTK2	PTK2 protein tyrosine kinase 2	0.995
SNX9	sorting nexin 9	0.994
DNM1	dynamin 1	0.988
DNM2	dynamin 2	0.988	Worm
ARRB1	arrestin, beta 1	0.985
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.985	Mouse
RAB1A	RAB1A, member RAS oncogene family	0.975
S100A6	S100 calcium binding protein A6	0.974	Human
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.974
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.973
FGFR2	fibroblast growth factor receptor 2	0.973
TRIM63	tripartite motif containing 63	0.963
ITSN1	intersectin 1 (SH3 domain protein)	0.961
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.960
SQSTM1	sequestosome 1	0.959
EEA1	early endosome antigen 1	0.954
SFN	stratifin	0.953
CDK7	cyclin-dependent kinase 7	0.952
GRB2	growth factor receptor-bound protein 2	0.949
THOC4	THO complex 4	0.948	Yeast
S100A8	S100 calcium binding protein A8	0.945	Human
ILK	integrin-linked kinase	0.941
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.937
JUN	jun proto-oncogene	0.932
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.926	Human Mouse
HSPA1B	heat shock 70kDa protein 1B	0.918
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.917
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.916
ABI1	abl-interactor 1	0.911
SEPT2	septin 2	0.910	Fly
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	0.910
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.906	Mouse
ERCC3	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	0.904
TOR1A	torsin family 1, member A (torsin A)	0.902
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.898
TTN	titin	0.897
TNNC1	troponin C type 1 (slow)	0.897	Mouse
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.891
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.890
RHOA	ras homolog gene family, member A	0.889	Yeast Mouse Worm Fly
ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	0.889
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.879
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.879
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.876	Fly
RACGAP1	Rac GTPase activating protein 1	0.873
RUVBL1	RuvB-like 1 (E. coli)	0.866
NCK2	NCK adaptor protein 2	0.865
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.861
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.855
RAB2A	RAB2A, member RAS oncogene family	0.852
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.852
UNC119	unc-119 homolog (C. elegans)	0.850
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.847	Mouse
STIP1	stress-induced-phosphoprotein 1	0.846	Yeast
RIN3	Ras and Rab interactor 3	0.839
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.838
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.838
TNNI1	troponin I type 1 (skeletal, slow)	0.838	Human
EGFR	epidermal growth factor receptor	0.835
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.835
SH3RF1	SH3 domain containing ring finger 1	0.827
GRB7	growth factor receptor-bound protein 7	0.824
RAB14	RAB14, member RAS oncogene family	0.824
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.823	Human
TPM1	tropomyosin 1 (alpha)	0.813	Human
CFL1	cofilin 1 (non-muscle)	0.809
HSPH1	heat shock 105kDa/110kDa protein 1	0.807	Yeast
S100A11	S100 calcium binding protein A11	0.805	Human
MAPK1	mitogen-activated protein kinase 1	0.798
MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	0.790
RANBP2	RAN binding protein 2	0.789
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.788
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.785
PKN3	protein kinase N3	0.773
S100A1	S100 calcium binding protein A1	0.769	Human
ADRBK1	adrenergic, beta, receptor kinase 1	0.766
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.762
FGFR1	fibroblast growth factor receptor 1	0.758
RHEB	Ras homolog enriched in brain	0.758	Fly
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.753
TMED2	transmembrane emp24 domain trafficking protein 2	0.752
RHOG	ras homolog gene family, member G (rho G)	0.739
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.737	Human Yeast Fly
FKBP4	FK506 binding protein 4, 59kDa	0.735
RHOC	ras homolog gene family, member C	0.732	Yeast Worm Fly
CCR5	chemokine (C-C motif) receptor 5	0.728
PDCD6IP	programmed cell death 6 interacting protein	0.728
CCNH	cyclin H	0.725
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.725	Rat
S100A4	S100 calcium binding protein A4	0.723	Human
ATF2	activating transcription factor 2	0.715	Human
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.712
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.703	Human
ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.698
NCK1	NCK adaptor protein 1	0.695
BZW1	basic leucine zipper and W2 domains 1	0.694
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.692
ACTG1	actin, gamma 1	0.689	Human
S100B	S100 calcium binding protein B	0.680	Human
NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa	0.678
SH3BP2	SH3-domain binding protein 2	0.677
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.672
ARHGAP1	Rho GTPase activating protein 1	0.672
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.670
HSPA4	heat shock 70kDa protein 4	0.670	Yeast
TNNI2	troponin I type 2 (skeletal, fast)	0.665	Human
HSPA1A	heat shock 70kDa protein 1A	0.664
ZYX	zyxin	0.661
NCAPG	non-SMC condensin I complex, subunit G	0.660
SOS1	son of sevenless homolog 1 (Drosophila)	0.656
MPDZ	multiple PDZ domain protein	0.656
GABARAPL1	GABA(A) receptor-associated protein like 1	0.654
RALGDS	ral guanine nucleotide dissociation stimulator	0.650
FLNA	filamin A, alpha	0.636
CYTH4	cytohesin 4	0.633
ZMYND11	zinc finger, MYND-type containing 11	0.632
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.630
GSK3B	glycogen synthase kinase 3 beta	0.627
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.626
SYNJ1	synaptojanin 1	0.621
ATP5L	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	0.620
GIMAP6	GTPase, IMAP family member 6	0.619	Human
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.618
CHD8	chromodomain helicase DNA binding protein 8	0.618
FNBP1	formin binding protein 1	0.616
CORO1A	coronin, actin binding protein, 1A	0.614
MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	0.611
RAB6A	RAB6A, member RAS oncogene family	0.611
SEC24D	SEC24 family, member D (S. cerevisiae)	0.610
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.609
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.605
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.604
LIMS1	LIM and senescent cell antigen-like domains 1	0.604
FNBP1L	formin binding protein 1-like	0.602
FGF10	fibroblast growth factor 10	0.601
MYO9B	myosin IXB	0.601
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.600
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.600
XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	0.597
ANXA7	annexin A7	0.597
VAV1	vav 1 guanine nucleotide exchange factor	0.593	Human Mouse Fly
RRAGA	Ras-related GTP binding A	0.592
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.590
ACTN2	actinin, alpha 2	0.589
BAG3	BCL2-associated athanogene 3	0.586
FASLG	Fas ligand (TNF superfamily, member 6)	0.582
NCKAP1	NCK-associated protein 1	0.581	Human
GDI2	GDP dissociation inhibitor 2	0.578	Yeast Rat Fly
FMNL1	formin-like 1	0.577
ACTA1	actin, alpha 1, skeletal muscle	0.574	Human
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.566	Human Yeast
MKI67	antigen identified by monoclonal antibody Ki-67	0.562
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.560
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.555	Human Yeast Worm
SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	0.555	Yeast
WIPF1	WAS/WASL interacting protein family, member 1	0.554
RAD51L3	RAD51-like 3 (S. cerevisiae)	0.545
SEPT7	septin 7	0.541	Fly
SMAD2	SMAD family member 2	0.540
RGS2	regulator of G-protein signaling 2, 24kDa	0.540	Rat
KIF1B	kinesin family member 1B	0.539	Mouse
PPARA	peroxisome proliferator-activated receptor alpha	0.539
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.536
EPHA7	EPH receptor A7	0.533	Human
MAPK14	mitogen-activated protein kinase 14	0.530
ATP5F1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	0.529
DLD	dihydrolipoamide dehydrogenase	0.529
MICALL1	MICAL-like 1	0.528
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.527
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.525
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.524
DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	0.520	Human Yeast
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.518
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.518
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.517
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.514
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.512
DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.511
NDUFA1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa	0.510
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.510
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.510
GMCL1	germ cell-less homolog 1 (Drosophila)	0.508
DOCK1	dedicator of cytokinesis 1	0.508	Human Fly
GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	0.507
PNPLA6	patatin-like phospholipase domain containing 6	0.506
CORO1C	coronin, actin binding protein, 1C	0.505
NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	0.502
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.501
ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	0.501
ARL2	ADP-ribosylation factor-like 2	0.500
GOLGA2	golgin A2	0.499
SURF4	surfeit 4	0.499
ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8	0.498
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.497
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.495	Rat
TJP2	tight junction protein 2 (zona occludens 2)	0.495
TPM2	tropomyosin 2 (beta)	0.494
SMC4	structural maintenance of chromosomes 4	0.493
GIMAP7	GTPase, IMAP family member 7	0.492
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.492
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.491
TMSB4X	thymosin beta 4, X-linked	0.488
SMYD1	SET and MYND domain containing 1	0.486
TRIM55	tripartite motif containing 55	0.482
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.480	Worm
CFL2	cofilin 2 (muscle)	0.479
SORBS1	sorbin and SH3 domain containing 1	0.475
S100A9	S100 calcium binding protein A9	0.474	Human
TSC2	tuberous sclerosis 2	0.474
FGF1	fibroblast growth factor 1 (acidic)	0.472	Human
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.468
PLCG1	phospholipase C, gamma 1	0.467	Human
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.466
SS18	synovial sarcoma translocation, chromosome 18	0.465
EIF2B5	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	0.464
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.462
YY1	YY1 transcription factor	0.460
ACTC1	actin, alpha, cardiac muscle 1	0.460
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.458
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.457	Yeast
ACTA2	actin, alpha 2, smooth muscle, aorta	0.457	Human
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.454
NGF	nerve growth factor (beta polypeptide)	0.452	Human
ZNF496	zinc finger protein 496	0.447
PSEN1	presenilin 1	0.444
RAB10	RAB10, member RAS oncogene family	0.441
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.439
TSC1	tuberous sclerosis 1	0.437
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.436
LRRK2	leucine-rich repeat kinase 2	0.435
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.434
EFNA5	ephrin-A5	0.434
GTF2H2	general transcription factor IIH, polypeptide 2, 44kDa	0.433
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.429
BIN1	bridging integrator 1	0.427	Rat
ARF6	ADP-ribosylation factor 6	0.427
RPTOR	regulatory associated protein of MTOR, complex 1	0.424
WDYHV1	WDYHV motif containing 1	0.419
RICTOR	RPTOR independent companion of MTOR, complex 2	0.412	Mouse
ARL8B	ADP-ribosylation factor-like 8B	0.411
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.410
PLXNB1	plexin B1	0.410	Human Mouse
TFRC	transferrin receptor (p90, CD71)	0.409
VCAM1	vascular cell adhesion molecule 1	0.408
RAP2C	RAP2C, member of RAS oncogene family	0.408	Human Yeast
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.406
JAG2	jagged 2	0.406
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.405
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.405
AGAP5	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5	0.404	Fly
ANK1	ankyrin 1, erythrocytic	0.403
CLASP1	cytoplasmic linker associated protein 1	0.402
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.400
ACTB	actin, beta	0.400	Human
RRAGC	Ras-related GTP binding C	0.398
KRT14	keratin 14	0.398
MAP2K2	mitogen-activated protein kinase kinase 2	0.397
PEA15	phosphoprotein enriched in astrocytes 15	0.394
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.393
RAD51L1	RAD51-like 1 (S. cerevisiae)	0.393
TRADD	TNFRSF1A-associated via death domain	0.392
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.392	Rat
CHD7	chromodomain helicase DNA binding protein 7	0.391	Human
TBCD	tubulin folding cofactor D	0.390
PKN2	protein kinase N2	0.389
HMHA1	histocompatibility (minor) HA-1	0.387	Human
LMAN1	lectin, mannose-binding, 1	0.383
RAB8A	RAB8A, member RAS oncogene family	0.382
NEB	nebulin	0.381
TRAF5	TNF receptor-associated factor 5	0.381
MAP2K4	mitogen-activated protein kinase kinase 4	0.380
CKM	creatine kinase, muscle	0.380
TMED7	transmembrane emp24 protein transport domain containing 7	0.379	Human
CHMP1A	chromatin modifying protein 1A	0.375
CAPN7	calpain 7	0.374
CUL4B	cullin 4B	0.374
HBXIP	hepatitis B virus x interacting protein	0.374
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.372	Yeast
STAT5A	signal transducer and activator of transcription 5A	0.372
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.372
SOD1	superoxide dismutase 1, soluble	0.371
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.371
PLD2	phospholipase D2	0.369
RPA1	replication protein A1, 70kDa	0.369
SPRY2	sprouty homolog 2 (Drosophila)	0.368	Mouse
NAV1	neuron navigator 1	0.368
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.367
AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	0.365	Fly
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.365
MVP	major vault protein	0.365
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.365
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.364
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.364
HMOX2	heme oxygenase (decycling) 2	0.363
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.360
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.359
COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.359
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.357	Yeast
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.356
EEF1G	eukaryotic translation elongation factor 1 gamma	0.355
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.354
PFN1	profilin 1	0.353
KIF14	kinesin family member 14	0.352
ACTN3	actinin, alpha 3	0.349
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.348
KIAA1539	KIAA1539	0.347
RAP1B	RAP1B, member of RAS oncogene family	0.347
CUL7	cullin 7	0.346
RAB7A	RAB7A, member RAS oncogene family	0.345
ARHGAP15	Rho GTPase activating protein 15	0.344
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.343
GRPEL1	GrpE-like 1, mitochondrial (E. coli)	0.343
ANKRD28	ankyrin repeat domain 28	0.342
NDUFB1	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa	0.342
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.340
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.334
FGF7	fibroblast growth factor 7	0.333	Human
ATPIF1	ATPase inhibitory factor 1	0.332
PLXNB2	plexin B2	0.330	Human Mouse
COX7C	cytochrome c oxidase subunit VIIc	0.328
EFHD2	EF-hand domain family, member D2	0.326
RND1	Rho family GTPase 1	0.325
MAPK3	mitogen-activated protein kinase 3	0.324
COX6C	cytochrome c oxidase subunit VIc	0.324
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.324
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.323
RAD51C	RAD51 homolog C (S. cerevisiae)	0.323
COX7A2	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	0.323
ASCC2	activating signal cointegrator 1 complex subunit 2	0.322
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.322
SEC31A	SEC31 homolog A (S. cerevisiae)	0.321
BAIAP2	BAI1-associated protein 2	0.321
APC	adenomatous polyposis coli	0.320
BAG1	BCL2-associated athanogene	0.320
EML3	echinoderm microtubule associated protein like 3	0.319
BCL2L1	BCL2-like 1	0.319
DCTN1	dynactin 1	0.319
PLEC	plectin	0.319
ARHGAP4	Rho GTPase activating protein 4	0.317	Human Rat
FAM190B	family with sequence similarity 190, member B	0.317
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.317
IPCEF1	interaction protein for cytohesin exchange factors 1	0.317	Rat
TK1	thymidine kinase 1, soluble	0.315
TAGLN2	transgelin 2	0.313
COX7B	cytochrome c oxidase subunit VIIb	0.313
ACAP3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	0.309
GCH1	GTP cyclohydrolase 1	0.308
MYBPC2	myosin binding protein C, fast type	0.308
SH3BP4	SH3-domain binding protein 4	0.308
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.306
ECT2	epithelial cell transforming sequence 2 oncogene	0.306
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.306
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.306
FGFR3	fibroblast growth factor receptor 3	0.305
RAP1A	RAP1A, member of RAS oncogene family	0.303	Human Yeast Mouse Rat Fly
FYB	FYN binding protein	0.302
GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	0.302
MAPK6	mitogen-activated protein kinase 6	0.302
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.301
SMC2	structural maintenance of chromosomes 2	0.300	Yeast
CAPNS1	calpain, small subunit 1	0.300
PLXND1	plexin D1	0.300	Human
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.299
DES	desmin	0.299
WRN	Werner syndrome, RecQ helicase-like	0.298
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.298
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.298
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.297
PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	0.297
REPS2	RALBP1 associated Eps domain containing 2	0.296
SHCBP1	SHC SH2-domain binding protein 1	0.294
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.293
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.293
GIPC1	GIPC PDZ domain containing family, member 1	0.292
CNN1	calponin 1, basic, smooth muscle	0.292
SMCR7	Smith-Magenis syndrome chromosome region, candidate 7	0.291
BAD	BCL2-associated agonist of cell death	0.291
GNG2	guanine nucleotide binding protein (G protein), gamma 2	0.289	Human
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.289	Mouse
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.288
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.288
GAB1	GRB2-associated binding protein 1	0.288
XAB2	XPA binding protein 2	0.285
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.285	Human Yeast Mouse Worm Fly
EPHA3	EPH receptor A3	0.285
ARL3	ADP-ribosylation factor-like 3	0.285	Mouse
DUSP1	dual specificity phosphatase 1	0.285
APLNR	apelin receptor	0.282
MYCBP2	MYC binding protein 2	0.281
PRR5	proline rich 5 (renal)	0.281
KIF23	kinesin family member 23	0.280	Human
USP9X	ubiquitin specific peptidase 9, X-linked	0.280
CCL5	chemokine (C-C motif) ligand 5	0.280	Human
AKAP13	A kinase (PRKA) anchor protein 13	0.280	Human
BDNF	brain-derived neurotrophic factor	0.279	Human
KCTD12	potassium channel tetramerisation domain containing 12	0.278
CCL8	chemokine (C-C motif) ligand 8	0.278	Human
RAB4A	RAB4A, member RAS oncogene family	0.277
RDX	radixin	0.277
GPSM3	G-protein signaling modulator 3	0.277
CCL13	chemokine (C-C motif) ligand 13	0.276	Human
ADAM15	ADAM metallopeptidase domain 15	0.276
ADRB2	adrenergic, beta-2-, receptor, surface	0.276	Human Rat
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.276
C19orf50	chromosome 19 open reading frame 50	0.275
CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.275
PARVA	parvin, alpha	0.275
CCL4	chemokine (C-C motif) ligand 4	0.274	Human
SH3PXD2A	SH3 and PX domains 2A	0.274
PDLIM7	PDZ and LIM domain 7 (enigma)	0.273
MYO1G	myosin IG	0.273	Human
RBBP7	retinoblastoma binding protein 7	0.272	Human
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.272
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.271
AMPH	amphiphysin	0.271	Rat
SH3RF3	SH3 domain containing ring finger 3	0.271
MINK1	misshapen-like kinase 1	0.270
CLTB	clathrin, light chain B	0.270
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.269
RBBP4	retinoblastoma binding protein 4	0.269
VIM	vimentin	0.268
LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.268
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.267
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.266	Human Yeast
COX4I1	cytochrome c oxidase subunit IV isoform 1	0.266
ZSWIM7	zinc finger, SWIM-type containing 7	0.266
GIMAP4	GTPase, IMAP family member 4	0.265	Human
RSF1	remodeling and spacing factor 1	0.263
DYNLL1	dynein, light chain, LC8-type 1	0.263
MFN1	mitofusin 1	0.263
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.261
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.261
DBNL	drebrin-like	0.261
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.261
TFG	TRK-fused gene	0.260
HSPB1	heat shock 27kDa protein 1	0.260
DPP4	dipeptidyl-peptidase 4	0.260
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.258
ARHGAP5	Rho GTPase activating protein 5	0.258	Fly
RAB1B	RAB1B, member RAS oncogene family	0.257	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.256
GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.256	Human Yeast
SAP18	Sin3A-associated protein, 18kDa	0.256
OSBPL3	oxysterol binding protein-like 3	0.256
EMP3	epithelial membrane protein 3	0.255
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.254
ZBED1	zinc finger, BED-type containing 1	0.253
CDK17	cyclin-dependent kinase 17	0.253
CNN2	calponin 2	0.252
MARK2	MAP/microtubule affinity-regulating kinase 2	0.252
MLF2	myeloid leukemia factor 2	0.252
TDP2	tyrosyl-DNA phosphodiesterase 2	0.251
NUDT18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	0.250
AHNAK	AHNAK nucleoprotein	0.250
GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	0.250	Human
MFAP1	microfibrillar-associated protein 1	0.250
GIMAP2	GTPase, IMAP family member 2	0.249	Human
TCAP	titin-cap (telethonin)	0.248
JUP	junction plakoglobin	0.247
MYO1C	myosin IC	0.246	Human Rat
RABGAP1L	RAB GTPase activating protein 1-like	0.245
PDE4DIP	phosphodiesterase 4D interacting protein	0.244
CIC	capicua homolog (Drosophila)	0.244
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.244
TMC6	transmembrane channel-like 6	0.243
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.242
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.241
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.240
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.240
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.240
CCL2	chemokine (C-C motif) ligand 2	0.240	Human
CHMP2B	chromatin modifying protein 2B	0.239
NRBF2	nuclear receptor binding factor 2	0.239
SRP68	signal recognition particle 68kDa	0.239
RAB3IP	RAB3A interacting protein (rabin3)	0.239
SYNJ2	synaptojanin 2	0.238
NOP2	NOP2 nucleolar protein homolog (yeast)	0.238
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.238
ESR2	estrogen receptor 2 (ER beta)	0.238
PCDH9	protocadherin 9	0.238
TNNT3	troponin T type 3 (skeletal, fast)	0.238
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.238
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.238
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.237
MYH14	myosin, heavy chain 14, non-muscle	0.236
KCTD3	potassium channel tetramerisation domain containing 3	0.236
PHF21A	PHD finger protein 21A	0.236
SRP14	signal recognition particle 14kDa (homologous Alu RNA binding protein)	0.235
RPLP1	ribosomal protein, large, P1	0.235
BIRC6	baculoviral IAP repeat containing 6	0.235
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.234
GIMAP1	GTPase, IMAP family member 1	0.234	Human
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.234
THOC2	THO complex 2	0.234
SH3GL2	SH3-domain GRB2-like 2	0.234
THRAP3	thyroid hormone receptor associated protein 3	0.232
NTF3	neurotrophin 3	0.232
LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	0.231
CRLF3	cytokine receptor-like factor 3	0.230
CSNK1E	casein kinase 1, epsilon	0.230
TNF	tumor necrosis factor	0.230
CLIC4	chloride intracellular channel 4	0.228
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.228	Human Fly
PPP5C	protein phosphatase 5, catalytic subunit	0.228
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.227
EPS15	epidermal growth factor receptor pathway substrate 15	0.227
EFNB2	ephrin-B2	0.226	Human
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.226
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.225
CSK	c-src tyrosine kinase	0.225
TAPBP	TAP binding protein (tapasin)	0.224
AREG	amphiregulin	0.224
S100A10	S100 calcium binding protein A10	0.224
SERP1	stress-associated endoplasmic reticulum protein 1	0.224
KRT8	keratin 8	0.224
PARVG	parvin, gamma	0.223
RABAC1	Rab acceptor 1 (prenylated)	0.223
CXCR5	chemokine (C-X-C motif) receptor 5	0.222
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.222
RAB22A	RAB22A, member RAS oncogene family	0.222
CCL3	chemokine (C-C motif) ligand 3	0.222	Human
PRKCA	protein kinase C, alpha	0.222
SMN1	survival of motor neuron 1, telomeric	0.222
HSPA8	heat shock 70kDa protein 8	0.221
UQCR11	ubiquinol-cytochrome c reductase, complex III subunit XI	0.221
ABI2	abl-interactor 2	0.221
UQCRB	ubiquinol-cytochrome c reductase binding protein	0.220
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.219
LZTR1	leucine-zipper-like transcription regulator 1	0.219
AP2A2	adaptor-related protein complex 2, alpha 2 subunit	0.219
ARF4	ADP-ribosylation factor 4	0.219	Yeast
MYBPC1	myosin binding protein C, slow type	0.217
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.217
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.216
CABIN1	calcineurin binding protein 1	0.215
MYH11	myosin, heavy chain 11, smooth muscle	0.215	Human
TRAF3	TNF receptor-associated factor 3	0.215
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.215
ACD	adrenocortical dysplasia homolog (mouse)	0.214
HOXA1	homeobox A1	0.214
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.214
SRD5A3	steroid 5 alpha-reductase 3	0.213
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.213
ATXN3	ataxin 3	0.213
WDR1	WD repeat domain 1	0.213
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.212	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.211
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.211	Human
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.211
BLM	Bloom syndrome, RecQ helicase-like	0.211
PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like	0.209
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.209
UROD	uroporphyrinogen decarboxylase	0.209
GSN	gelsolin	0.209
HIPK2	homeodomain interacting protein kinase 2	0.208
TRAF1	TNF receptor-associated factor 1	0.208
TOR1AIP2	torsin A interacting protein 2	0.208
FHOD1	formin homology 2 domain containing 1	0.208
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.207
SNX4	sorting nexin 4	0.207
RUSC2	RUN and SH3 domain containing 2	0.207
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.207
AKAP8	A kinase (PRKA) anchor protein 8	0.207
AURKB	aurora kinase B	0.207
SCYL2	SCY1-like 2 (S. cerevisiae)	0.206
LMNA	lamin A/C	0.206
FAF1	Fas (TNFRSF6) associated factor 1	0.206
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.206	Mouse
CASQ2	calsequestrin 2 (cardiac muscle)	0.205
RND3	Rho family GTPase 3	0.205
NSUN2	NOP2/Sun domain family, member 2	0.204
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.204
RAD52	RAD52 homolog (S. cerevisiae)	0.203
SKIL	SKI-like oncogene	0.202
LCP1	lymphocyte cytosolic protein 1 (L-plastin)	0.201
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.201
STAT4	signal transducer and activator of transcription 4	0.201
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.201
CAB39	calcium binding protein 39	0.201
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.201
AKAP12	A kinase (PRKA) anchor protein 12	0.200
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.200	Human
TNNT2	troponin T type 2 (cardiac)	0.200
TNNC2	troponin C type 2 (fast)	0.200
KIAA0930	KIAA0930	0.200
LAD1	ladinin 1	0.200
LDB3	LIM domain binding 3	0.200
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.200
NDP	Norrie disease (pseudoglioma)	0.200
C19orf39	chromosome 19 open reading frame 39	0.199
FHL2	four and a half LIM domains 2	0.199
CCL19	chemokine (C-C motif) ligand 19	0.199	Human Mouse
PTPRS	protein tyrosine phosphatase, receptor type, S	0.199
MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1	0.199
EHD1	EH-domain containing 1	0.199	Worm
ATP5H	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d	0.198
GIMAP8	GTPase, IMAP family member 8	0.197
YTHDC2	YTH domain containing 2	0.197
AKAP6	A kinase (PRKA) anchor protein 6	0.197
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.197
MAP2K7	mitogen-activated protein kinase kinase 7	0.196
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.196
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.196
THOC5	THO complex 5	0.196
RUNDC3A	RUN domain containing 3A	0.196
DLGAP4	discs, large (Drosophila) homolog-associated protein 4	0.195
CDV3	CDV3 homolog (mouse)	0.195
GDF10	growth differentiation factor 10	0.195
GAS7	growth arrest-specific 7	0.195
PYGM	phosphorylase, glycogen, muscle	0.194
VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	0.194
IQGAP1	IQ motif containing GTPase activating protein 1	0.193
MCC	mutated in colorectal cancers	0.192
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.192	Human
TMSB10	thymosin beta 10	0.192
RAD23B	RAD23 homolog B (S. cerevisiae)	0.192
EPHB2	EPH receptor B2	0.192	Human
MYL9	myosin, light chain 9, regulatory	0.191
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.191
EZR	ezrin	0.190
TTC37	tetratricopeptide repeat domain 37	0.190
TJP1	tight junction protein 1 (zona occludens 1)	0.190
SMAD3	SMAD family member 3	0.190
COPG	coatomer protein complex, subunit gamma	0.190
MAPK10	mitogen-activated protein kinase 10	0.189
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.189
C19orf61	chromosome 19 open reading frame 61	0.189
SASH3	SAM and SH3 domain containing 3	0.189
TNNI3	troponin I type 3 (cardiac)	0.188
GOLGB1	golgin B1	0.188
ANKFY1	ankyrin repeat and FYVE domain containing 1	0.187
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.186	Fly
PDE4A	phosphodiesterase 4A, cAMP-specific	0.186
MAP2	microtubule-associated protein 2	0.185
SPRY4	sprouty homolog 4 (Drosophila)	0.185
RHOD	ras homolog gene family, member D	0.185
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.184
RAB13	RAB13, member RAS oncogene family	0.183
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.183
WNT3A	wingless-type MMTV integration site family, member 3A	0.183
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.182
UBASH3B	ubiquitin associated and SH3 domain containing B	0.182
CSRP1	cysteine and glycine-rich protein 1	0.182
S100A2	S100 calcium binding protein A2	0.182	Human
CELF2	CUGBP, Elav-like family member 2	0.182
TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.182
PARP2	poly (ADP-ribose) polymerase 2	0.182
PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B	0.181
NUDC	nuclear distribution gene C homolog (A. nidulans)	0.181
TMOD3	tropomodulin 3 (ubiquitous)	0.181
PKP3	plakophilin 3	0.181	Human
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.181
TBL3	transducin (beta)-like 3	0.180
ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6	0.179
BRCA2	breast cancer 2, early onset	0.178
DOK4	docking protein 4	0.178
RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.178
CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	0.177
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.177
CD63	CD63 molecule	0.176
PBK	PDZ binding kinase	0.176
PDIA3	protein disulfide isomerase family A, member 3	0.176
PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	0.176
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.175
TRPM7	transient receptor potential cation channel, subfamily M, member 7	0.175
PRRX2	paired related homeobox 2	0.175
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.175
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.175
BABAM1	BRISC and BRCA1 A complex member 1	0.175
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.174
RGS19	regulator of G-protein signaling 19	0.174
PHTF2	putative homeodomain transcription factor 2	0.174
RABGAP1	RAB GTPase activating protein 1	0.173
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.173
PAWR	PRKC, apoptosis, WT1, regulator	0.173
TNNT1	troponin T type 1 (skeletal, slow)	0.173	Human
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.173
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.173	Human Mouse Rat
RHOQ	ras homolog gene family, member Q	0.172
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.172
REEP5	receptor accessory protein 5	0.172
RAB11A	RAB11A, member RAS oncogene family	0.171
SAMD4A	sterile alpha motif domain containing 4A	0.171
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.171
CCR7	chemokine (C-C motif) receptor 7	0.171
DAAM1	dishevelled associated activator of morphogenesis 1	0.171
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.170	Mouse
GPSM2	G-protein signaling modulator 2	0.170	Fly
PARK7	Parkinson disease (autosomal recessive, early onset) 7	0.169
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.169
MCM10	minichromosome maintenance complex component 10	0.169
STX12	syntaxin 12	0.168
CALCA	calcitonin-related polypeptide alpha	0.168
VAV2	vav 2 guanine nucleotide exchange factor	0.168
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.168
PPAP2B	phosphatidic acid phosphatase type 2B	0.167
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.167
TMED9	transmembrane emp24 protein transport domain containing 9	0.167
SLC39A7	solute carrier family 39 (zinc transporter), member 7	0.167
MRVI1	murine retrovirus integration site 1 homolog	0.166
RARG	retinoic acid receptor, gamma	0.166
RAB18	RAB18, member RAS oncogene family	0.166
CACNB1	calcium channel, voltage-dependent, beta 1 subunit	0.166
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.166
EXOC1	exocyst complex component 1	0.166
BATF	basic leucine zipper transcription factor, ATF-like	0.165
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.165
COX6B1	cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)	0.165
MTA3	metastasis associated 1 family, member 3	0.165
PDZK1	PDZ domain containing 1	0.165
USP42	ubiquitin specific peptidase 42	0.164
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.164
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.164
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.164
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.164
ALS2CL	ALS2 C-terminal like	0.162	Fly
C9orf25	chromosome 9 open reading frame 25	0.162
FAM65A	family with sequence similarity 65, member A	0.162
GMFG	glia maturation factor, gamma	0.162
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.161	Human
LPP	LIM domain containing preferred translocation partner in lipoma	0.161
ARCN1	archain 1	0.161
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.160
ATXN10	ataxin 10	0.160
TLN1	talin 1	0.160
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.160
AP1B1	adaptor-related protein complex 1, beta 1 subunit	0.160
NLRC4	NLR family, CARD domain containing 4	0.159
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.159
CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.159
DNA2	DNA replication helicase 2 homolog (yeast)	0.159
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.158	Human
DGKZ	diacylglycerol kinase, zeta	0.158
CYTIP	cytohesin 1 interacting protein	0.158
PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	0.158
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.157
CDKL5	cyclin-dependent kinase-like 5	0.157	Rat
KIF1C	kinesin family member 1C	0.157
PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	0.157
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.157
MATK	megakaryocyte-associated tyrosine kinase	0.157
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.156