IMP: Integrative Multi-species Prediction

Homo sapiens

69 genes annotated in human

Multi-species View

negative regulation of wnt signaling pathway

GO:0030178

Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of wnt signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of wnt signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1.000
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.999	Mouse
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.998
AXIN1	axin 1	0.993
SMAD3	SMAD family member 3	0.982
CREBBP	CREB binding protein	0.971
ZFYVE9	zinc finger, FYVE domain containing 9	0.953
PPP6C	protein phosphatase 6, catalytic subunit	0.953
SMAD7	SMAD family member 7	0.950
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.944
LRP6	low density lipoprotein receptor-related protein 6	0.938	Human Mouse
GSK3B	glycogen synthase kinase 3 beta	0.922	Worm
STK3	serine/threonine kinase 3	0.912
PPP6R2	protein phosphatase 6, regulatory subunit 2	0.888
BTRC	beta-transducin repeat containing	0.876	Fly
HDAC1	histone deacetylase 1	0.848	Mouse
PSEN1	presenilin 1	0.839
SUFU	suppressor of fused homolog (Drosophila)	0.839
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.836
AFF1	AF4/FMR2 family, member 1	0.830
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.825
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.811
SKP1	S-phase kinase-associated protein 1	0.791
APC	adenomatous polyposis coli	0.791
HIPK3	homeodomain interacting protein kinase 3	0.773
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.757
STK4	serine/threonine kinase 4	0.751
IGF1R	insulin-like growth factor 1 receptor	0.739
SMAD4	SMAD family member 4	0.669
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.653
AR	androgen receptor	0.632
SMAD2	SMAD family member 2	0.623
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.611
INSR	insulin receptor	0.606
EGFR	epidermal growth factor receptor	0.582
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.563
YAP1	Yes-associated protein 1	0.562	Human
PPP6R1	protein phosphatase 6, regulatory subunit 1	0.543
FBXW11	F-box and WD repeat domain containing 11	0.542	Fly
ANKRD28	ankyrin repeat domain 28	0.539	Human
JUP	junction plakoglobin	0.522	Zebrafish
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.519
FZD1	frizzled homolog 1 (Drosophila)	0.519	Human Mouse
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.502
POU3F2	POU class 3 homeobox 2	0.497
WNT3A	wingless-type MMTV integration site family, member 3A	0.485	Human
SNAI1	snail homolog 1 (Drosophila)	0.479	Human
ARHGAP1	Rho GTPase activating protein 1	0.460
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.429
CTNND1	catenin (cadherin-associated protein), delta 1	0.426
DSP	desmoplakin	0.423
BMP7	bone morphogenetic protein 7	0.422
GIPC1	GIPC PDZ domain containing family, member 1	0.420
BTBD2	BTB (POZ) domain containing 2	0.419
BMPR1A	bone morphogenetic protein receptor, type IA	0.416
LEF1	lymphoid enhancer-binding factor 1	0.397
BBS10	Bardet-Biedl syndrome 10	0.397
CDK6	cyclin-dependent kinase 6	0.396
CSNK1E	casein kinase 1, epsilon	0.389	Mouse
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.382
ATXN1	ataxin 1	0.373
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.367
TCF4	transcription factor 4	0.362
PAX3	paired box 3	0.359
FOXD3	forkhead box D3	0.323
JUB	jub, ajuba homolog (Xenopus laevis)	0.310
FSTL1	follistatin-like 1	0.309
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.290
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.286
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.286
TBX5	T-box 5	0.275
VHL	von Hippel-Lindau tumor suppressor	0.274
SFRP1	secreted frizzled-related protein 1	0.270
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.268
CTNNBIP1	catenin, beta interacting protein 1	0.251
ZNF512B	zinc finger protein 512B	0.245
NCOR1	nuclear receptor corepressor 1	0.245
ERBB2IP	erbb2 interacting protein	0.243
GLIS2	GLIS family zinc finger 2	0.242	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.241
MARK3	MAP/microtubule affinity-regulating kinase 3	0.239
GATA4	GATA binding protein 4	0.218
IRS2	insulin receptor substrate 2	0.214
TSC1	tuberous sclerosis 1	0.207
SAV1	salvador homolog 1 (Drosophila)	0.200
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.197
PPARA	peroxisome proliferator-activated receptor alpha	0.194
RUNX1	runt-related transcription factor 1	0.193
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.191
STK38L	serine/threonine kinase 38 like	0.185
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.184	Mouse
TP73	tumor protein p73	0.181
IRS1	insulin receptor substrate 1	0.178
EPHB1	EPH receptor B1	0.178
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.172
ANAPC11	anaphase promoting complex subunit 11	0.153
SFN	stratifin	0.150
WNT5A	wingless-type MMTV integration site family, member 5A	0.145
MYO6	myosin VI	0.143
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.141
STAT5B	signal transducer and activator of transcription 5B	0.137	Fly
FZD7	frizzled homolog 7 (Drosophila)	0.137	Human
SOX9	SRY (sex determining region Y)-box 9	0.136	Human Mouse
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.130
STK36	serine/threonine kinase 36	0.129
HMGA1	high mobility group AT-hook 1	0.129
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.125
WNT1	wingless-type MMTV integration site family, member 1	0.124	Human
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.124
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.121
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.121
TUBA1A	tubulin, alpha 1a	0.118
HOXD9	homeobox D9	0.118
KAT2B	K(lysine) acetyltransferase 2B	0.118
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.116
AFF4	AF4/FMR2 family, member 4	0.116
KRT8	keratin 8	0.114
PRRC2A	proline-rich coiled-coil 2A	0.111
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.111
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.110
NCOA2	nuclear receptor coactivator 2	0.109
GLI1	GLI family zinc finger 1	0.106
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.105
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.101
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.100
FERMT2	fermitin family member 2	0.097
DBP	D site of albumin promoter (albumin D-box) binding protein	0.094
SALL2	sal-like 2 (Drosophila)	0.094
PTPRF	protein tyrosine phosphatase, receptor type, F	0.091
AXIN2	axin 2	0.090
AMOT	angiomotin	0.087
ZMYND8	zinc finger, MYND-type containing 8	0.086
JAG2	jagged 2	0.086
NCOR2	nuclear receptor corepressor 2	0.086
FOXO1	forkhead box O1	0.086	Mouse
FZD8	frizzled homolog 8 (Drosophila)	0.085	Human
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.084
SH3RF1	SH3 domain containing ring finger 1	0.083
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.083
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.083
SMAD9	SMAD family member 9	0.083
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.082
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.082
CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	0.082
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.082
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.082
PXN	paxillin	0.079
B9D2	B9 protein domain 2	0.078
HES1	hairy and enhancer of split 1, (Drosophila)	0.078
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.077
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.077
FGF18	fibroblast growth factor 18	0.077
TJP1	tight junction protein 1 (zona occludens 1)	0.075
HDAC6	histone deacetylase 6	0.075
PPP6R3	protein phosphatase 6, regulatory subunit 3	0.073
UXT	ubiquitously-expressed transcript	0.071
ERRFI1	ERBB receptor feedback inhibitor 1	0.070
NDP	Norrie disease (pseudoglioma)	0.070
DST	dystonin	0.069
FBLN1	fibulin 1	0.069
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.069
WNT11	wingless-type MMTV integration site family, member 11	0.068
WIF1	WNT inhibitory factor 1	0.068	Zebrafish
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.068
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.068
SH2B1	SH2B adaptor protein 1	0.068
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.068
HIC1	hypermethylated in cancer 1	0.067
FRMD5	FERM domain containing 5	0.067
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.067
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.066
PCDHA4	protocadherin alpha 4	0.065
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.064
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.064
FOXF2	forkhead box F2	0.064
FGFR1	fibroblast growth factor receptor 1	0.063
WEE1	WEE1 homolog (S. pombe)	0.063
SLIT2	slit homolog 2 (Drosophila)	0.061
AMOTL2	angiomotin like 2	0.061
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.060
BMP2	bone morphogenetic protein 2	0.060
MPRIP	myosin phosphatase Rho interacting protein	0.060
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.058
CUX1	cut-like homeobox 1	0.058
PML	promyelocytic leukemia	0.057
BMP4	bone morphogenetic protein 4	0.057	Human
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.056
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.056
TGFB2	transforming growth factor, beta 2	0.055
CTBP1	C-terminal binding protein 1	0.055
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.055
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.055
KLF5	Kruppel-like factor 5 (intestinal)	0.055
NOG	noggin	0.055
INHBB	inhibin, beta B	0.054
STAT5A	signal transducer and activator of transcription 5A	0.054	Fly
SOCS1	suppressor of cytokine signaling 1	0.054
TGFB3	transforming growth factor, beta 3	0.054
MEOX2	mesenchyme homeobox 2	0.054
ANKRD52	ankyrin repeat domain 52	0.053	Human
SH3GL3	SH3-domain GRB2-like 3	0.053
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.053
DOCK7	dedicator of cytokinesis 7	0.053
TCEA2	transcription elongation factor A (SII), 2	0.053
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.052
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.052
PIAS4	protein inhibitor of activated STAT, 4	0.052
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.052
CCND3	cyclin D3	0.052
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.052
SOX11	SRY (sex determining region Y)-box 11	0.052	Human
CAPRIN2	caprin family member 2	0.052
DPYSL4	dihydropyrimidinase-like 4	0.052
EP300	E1A binding protein p300	0.051
KDM1A	lysine (K)-specific demethylase 1A	0.051
MTAP	methylthioadenosine phosphorylase	0.051
STAP2	signal transducing adaptor family member 2	0.050
HIPK2	homeodomain interacting protein kinase 2	0.050
PRKCA	protein kinase C, alpha	0.050
JAG1	jagged 1	0.050
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.050
DEDD	death effector domain containing	0.050
LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	0.049
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.049
ATF3	activating transcription factor 3	0.049
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.048
DSC2	desmocollin 2	0.048
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.048
BCR	breakpoint cluster region	0.048
TNS4	tensin 4	0.048
FOXA2	forkhead box A2	0.048
PRRX1	paired related homeobox 1	0.048
ZMYM2	zinc finger, MYM-type 2	0.048
CCND2	cyclin D2	0.047
MARCKSL1	MARCKS-like 1	0.046
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.046
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.046
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.046
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.046
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.046
AMOTL1	angiomotin like 1	0.045
KIF23	kinesin family member 23	0.045
ANKRD44	ankyrin repeat domain 44	0.044	Human
ELF5	E74-like factor 5 (ets domain transcription factor)	0.044
PEX26	peroxisomal biogenesis factor 26	0.043
SDC1	syndecan 1	0.043
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.043
USP10	ubiquitin specific peptidase 10	0.042
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.042
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.042
LRP2	low density lipoprotein receptor-related protein 2	0.041	Human
TJP2	tight junction protein 2 (zona occludens 2)	0.041
REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	0.041
UNC119B	unc-119 homolog B (C. elegans)	0.041
COL5A1	collagen, type V, alpha 1	0.041
SOX21	SRY (sex determining region Y)-box 21	0.040
LAD1	ladinin 1	0.040
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.040
MIB1	mindbomb homolog 1 (Drosophila)	0.040
NCOA1	nuclear receptor coactivator 1	0.039
APLP1	amyloid beta (A4) precursor-like protein 1	0.039
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.039
TOX4	TOX high mobility group box family member 4	0.039
PTK7	PTK7 protein tyrosine kinase 7	0.038	Fly
WNT2	wingless-type MMTV integration site family member 2	0.038	Human
DPPA4	developmental pluripotency associated 4	0.038
GSK3A	glycogen synthase kinase 3 alpha	0.038	Worm
NEUROG2	neurogenin 2	0.038
THBS2	thrombospondin 2	0.038
HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14	0.038
CAPN6	calpain 6	0.038
PTCH1	patched 1	0.038
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.038
MAPK1	mitogen-activated protein kinase 1	0.038
SKIL	SKI-like oncogene	0.038
TAOK1	TAO kinase 1	0.037
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.037
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.037
COL11A1	collagen, type XI, alpha 1	0.037
PRRX2	paired related homeobox 2	0.037
FGF4	fibroblast growth factor 4	0.037
TGFB1	transforming growth factor, beta 1	0.037
SOX4	SRY (sex determining region Y)-box 4	0.037	Human
NCSTN	nicastrin	0.036
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.036
CBX5	chromobox homolog 5	0.036
FBXW2	F-box and WD repeat domain containing 2	0.035
EHF	ets homologous factor	0.035
FGF3	fibroblast growth factor 3	0.035
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.035
DSG2	desmoglein 2	0.035
NKD1	naked cuticle homolog 1 (Drosophila)	0.035
FGF8	fibroblast growth factor 8 (androgen-induced)	0.035
FOXF1	forkhead box F1	0.035
ELK1	ELK1, member of ETS oncogene family	0.035
LRRK2	leucine-rich repeat kinase 2	0.035
TP53BP2	tumor protein p53 binding protein, 2	0.035
WWTR1	WW domain containing transcription regulator 1	0.035
AQP5	aquaporin 5	0.035
PLCG1	phospholipase C, gamma 1	0.035
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.034
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.034
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.034
CDK19	cyclin-dependent kinase 19	0.034
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.033
LIMD1	LIM domains containing 1	0.033	Mouse
RBPMS	RNA binding protein with multiple splicing	0.033
NUAK1	NUAK family, SNF1-like kinase, 1	0.033
GLIS3	GLIS family zinc finger 3	0.033	Human
GPC4	glypican 4	0.033	Fly
DLX4	distal-less homeobox 4	0.033
NOTCH1	notch 1	0.033	Mouse
RHOD	ras homolog gene family, member D	0.033
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.033
OBSL1	obscurin-like 1	0.032
GAS1	growth arrest-specific 1	0.032
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.032
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.032
PDGFC	platelet derived growth factor C	0.032
SOX1	SRY (sex determining region Y)-box 1	0.032	Human
SNX18	sorting nexin 18	0.032
FRMD6	FERM domain containing 6	0.032
GLI3	GLI family zinc finger 3	0.032
MED29	mediator complex subunit 29	0.032
SOX7	SRY (sex determining region Y)-box 7	0.032	Human
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.032
GPR161	G protein-coupled receptor 161	0.032
EMD	emerin	0.031
NCOA6	nuclear receptor coactivator 6	0.031
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.031
NFIB	nuclear factor I/B	0.031
DAZAP2	DAZ associated protein 2	0.031
ADAM15	ADAM metallopeptidase domain 15	0.031
MED16	mediator complex subunit 16	0.031
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.031
TCF7	transcription factor 7 (T-cell specific, HMG-box)	0.031	Human
IL2RB	interleukin 2 receptor, beta	0.031
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.031
POU3F1	POU class 3 homeobox 1	0.031
RPL28	ribosomal protein L28	0.031
OPTN	optineurin	0.031
ATN1	atrophin 1	0.030
KDM2A	lysine (K)-specific demethylase 2A	0.030
CRMP1	collapsin response mediator protein 1	0.030
CRYAB	crystallin, alpha B	0.030
FEZF2	FEZ family zinc finger 2	0.030
ECT2	epithelial cell transforming sequence 2 oncogene	0.030	Fly
WNT10A	wingless-type MMTV integration site family, member 10A	0.030	Human
CXXC5	CXXC finger protein 5	0.030	Human
MAPK8	mitogen-activated protein kinase 8	0.030
MSX1	msh homeobox 1	0.030
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.030
SOX13	SRY (sex determining region Y)-box 13	0.030
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.029
SFRP2	secreted frizzled-related protein 2	0.029
PKP4	plakophilin 4	0.029	Human
EPHB3	EPH receptor B3	0.029
CADM4	cell adhesion molecule 4	0.029
ELL3	elongation factor RNA polymerase II-like 3	0.029
COL2A1	collagen, type II, alpha 1	0.029
MYO10	myosin X	0.029
TGFBR1	transforming growth factor, beta receptor 1	0.029
ROR1	receptor tyrosine kinase-like orphan receptor 1	0.029
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.029
SPRED1	sprouty-related, EVH1 domain containing 1	0.029
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.029
C1QL1	complement component 1, q subcomponent-like 1	0.028
ZNF581	zinc finger protein 581	0.028
EFHD1	EF-hand domain family, member D1	0.028
RBMS3	RNA binding motif, single stranded interacting protein 3	0.028
RBL1	retinoblastoma-like 1 (p107)	0.028
POU5F1	POU class 5 homeobox 1	0.028
XIAP	X-linked inhibitor of apoptosis	0.028
MDK	midkine (neurite growth-promoting factor 2)	0.028
WNT6	wingless-type MMTV integration site family, member 6	0.028	Human
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.028
WNT3	wingless-type MMTV integration site family, member 3	0.028	Human
CEP164	centrosomal protein 164kDa	0.028
PCDH7	protocadherin 7	0.028
BRD3	bromodomain containing 3	0.028
LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	0.028
ZFPM1	zinc finger protein, multitype 1	0.028
PTPRG	protein tyrosine phosphatase, receptor type, G	0.028
CDX2	caudal type homeobox 2	0.027
BSG	basigin (Ok blood group)	0.027
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	0.027
WNT4	wingless-type MMTV integration site family, member 4	0.027
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.027
FHOD3	formin homology 2 domain containing 3	0.027
ZNF764	zinc finger protein 764	0.027
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.027
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.027
MAPT	microtubule-associated protein tau	0.027
ATXN1L	ataxin 1-like	0.027
GATA5	GATA binding protein 5	0.027
TNC	tenascin C	0.027
COL4A6	collagen, type IV, alpha 6	0.027
NUMA1	nuclear mitotic apparatus protein 1	0.027
TUBA3E	tubulin, alpha 3e	0.027
CDH5	cadherin 5, type 2 (vascular endothelium)	0.027
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.027
IGBP1	immunoglobulin (CD79A) binding protein 1	0.027
FZD2	frizzled homolog 2 (Drosophila)	0.026	Human
DOCK6	dedicator of cytokinesis 6	0.026
LIMK1	LIM domain kinase 1	0.026
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.026
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.026
FOXG1	forkhead box G1	0.026
ATXN7L2	ataxin 7-like 2	0.026
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.026
SYMPK	symplekin	0.026
LPHN1	latrophilin 1	0.026
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.026
TRIM25	tripartite motif containing 25	0.026
GDF6	growth differentiation factor 6	0.026
FGD1	FYVE, RhoGEF and PH domain containing 1	0.026
MAPK11	mitogen-activated protein kinase 11	0.026
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.026
APP	amyloid beta (A4) precursor protein	0.026
SIX2	SIX homeobox 2	0.025
CLTC	clathrin, heavy chain (Hc)	0.025
GABARAP	GABA(A) receptor-associated protein	0.025
NKX2-2	NK2 homeobox 2	0.025
WNT5B	wingless-type MMTV integration site family, member 5B	0.025	Human
FOXB1	forkhead box B1	0.025
NOTCH3	notch 3	0.025
MDFI	MyoD family inhibitor	0.025
FGF2	fibroblast growth factor 2 (basic)	0.025
SHH	sonic hedgehog	0.025
CAV2	caveolin 2	0.025
CCNDBP1	cyclin D-type binding-protein 1	0.025
DSC3	desmocollin 3	0.025
SNAI2	snail homolog 2 (Drosophila)	0.025
EN1	engrailed homeobox 1	0.025
HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	0.025
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.025
RGS2	regulator of G-protein signaling 2, 24kDa	0.025
NOTCH2	notch 2	0.025
GDF10	growth differentiation factor 10	0.025
GLI2	GLI family zinc finger 2	0.025	Human
LDLR	low density lipoprotein receptor	0.025
TRPS1	trichorhinophalangeal syndrome I	0.025
BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	0.025
TBX2	T-box 2	0.025
F2R	coagulation factor II (thrombin) receptor	0.025
FAM123B	family with sequence similarity 123B	0.025
EPHB4	EPH receptor B4	0.025
XAB2	XPA binding protein 2	0.025
SOX5	SRY (sex determining region Y)-box 5	0.025
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.024
PPAP2B	phosphatidic acid phosphatase type 2B	0.024
POSTN	periostin, osteoblast specific factor	0.024
EFNB2	ephrin-B2	0.024
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.024
SETD1A	SET domain containing 1A	0.024
TEAD4	TEA domain family member 4	0.024
MED26	mediator complex subunit 26	0.024
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.024	Human Zebrafish
FZD10	frizzled homolog 10 (Drosophila)	0.024	Human
FOXC1	forkhead box C1	0.024
HOXB13	homeobox B13	0.024
ITGB5	integrin, beta 5	0.024
JUN	jun proto-oncogene	0.024
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.024
HSPB1	heat shock 27kDa protein 1	0.024
IER2	immediate early response 2	0.024
MAVS	mitochondrial antiviral signaling protein	0.024
NDRG1	N-myc downstream regulated 1	0.024
SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like	0.024
EFNB3	ephrin-B3	0.024
SREBF1	sterol regulatory element binding transcription factor 1	0.024
GRB7	growth factor receptor-bound protein 7	0.024	Human
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.024
SH3GLB2	SH3-domain GRB2-like endophilin B2	0.024
PATZ1	POZ (BTB) and AT hook containing zinc finger 1	0.024
USP36	ubiquitin specific peptidase 36	0.023
OLIG2	oligodendrocyte lineage transcription factor 2	0.023
TRIL	TLR4 interactor with leucine-rich repeats	0.023
LHFP	lipoma HMGIC fusion partner	0.023
VAV2	vav 2 guanine nucleotide exchange factor	0.023
PERP	PERP, TP53 apoptosis effector	0.023
CXCL14	chemokine (C-X-C motif) ligand 14	0.023
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.023
FOXO3	forkhead box O3	0.023	Zebrafish Mouse
MEX3B	mex-3 homolog B (C. elegans)	0.023
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.023
FLI1	Friend leukemia virus integration 1	0.023
GJA1	gap junction protein, alpha 1, 43kDa	0.023
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.023
NKX3-2	NK3 homeobox 2	0.023
FILIP1L	filamin A interacting protein 1-like	0.023
CELF3	CUGBP, Elav-like family member 3	0.023
EGR2	early growth response 2	0.023
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.023
ENAH	enabled homolog (Drosophila)	0.023
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.023
ST14	suppression of tumorigenicity 14 (colon carcinoma)	0.023
PAX6	paired box 6	0.023
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.022
STRN3	striatin, calmodulin binding protein 3	0.022
CHRD	chordin	0.022
MXRA5	matrix-remodelling associated 5	0.022
LRP5	low density lipoprotein receptor-related protein 5	0.022	Human
RND3	Rho family GTPase 3	0.022
WBP1	WW domain binding protein 1	0.022
TEAD3	TEA domain family member 3	0.022
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.022
TNIP1	TNFAIP3 interacting protein 1	0.022
SYT11	synaptotagmin XI	0.022
QPRT	quinolinate phosphoribosyltransferase	0.022
PEG10	paternally expressed 10	0.022
AGTPBP1	ATP/GTP binding protein 1	0.022
PMEPA1	prostate transmembrane protein, androgen induced 1	0.022
KRT18	keratin 18	0.022
NFYA	nuclear transcription factor Y, alpha	0.022
UBA6	ubiquitin-like modifier activating enzyme 6	0.022
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.022
TWIST1	twist homolog 1 (Drosophila)	0.022
FAM117B	family with sequence similarity 117, member B	0.022
EPAS1	endothelial PAS domain protein 1	0.022
SUPT5H	suppressor of Ty 5 homolog (S. cerevisiae)	0.022
RBBP5	retinoblastoma binding protein 5	0.022
IGSF21	immunoglobin superfamily, member 21	0.022
SP5	Sp5 transcription factor	0.022
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.022
VEGFC	vascular endothelial growth factor C	0.022
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.022
POU3F3	POU class 3 homeobox 3	0.021
CTCF	CCCTC-binding factor (zinc finger protein)	0.021
PTPRK	protein tyrosine phosphatase, receptor type, K	0.021
FOXL2	forkhead box L2	0.021
MEIS2	Meis homeobox 2	0.021
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	0.021
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.021
SAP30	Sin3A-associated protein, 30kDa	0.021
PCSK5	proprotein convertase subtilisin/kexin type 5	0.021
GFI1B	growth factor independent 1B transcription repressor	0.021
MTA2	metastasis associated 1 family, member 2	0.021
PDGFA	platelet-derived growth factor alpha polypeptide	0.021
KRT5	keratin 5	0.021
ITGB4	integrin, beta 4	0.021
DCX	doublecortin	0.021
GPC3	glypican 3	0.021	Rat
CLASP1	cytoplasmic linker associated protein 1	0.021
PTHLH	parathyroid hormone-like hormone	0.021
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.021
DTX1	deltex homolog 1 (Drosophila)	0.021
RRAS	related RAS viral (r-ras) oncogene homolog	0.021
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.021
CALD1	caldesmon 1	0.021
LIMK2	LIM domain kinase 2	0.021
NINL	ninein-like	0.021
FBN3	fibrillin 3	0.021
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.021
IPO11	importin 11	0.021
HAS2	hyaluronan synthase 2	0.021
FOXQ1	forkhead box Q1	0.021
ZBTB33	zinc finger and BTB domain containing 33	0.021
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.020
PITX1	paired-like homeodomain 1	0.020
FHL2	four and a half LIM domains 2	0.020
EFNA3	ephrin-A3	0.020
VLDLR	very low density lipoprotein receptor	0.020
TAL1	T-cell acute lymphocytic leukemia 1	0.020
NKD2	naked cuticle homolog 2 (Drosophila)	0.020
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.020
HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	0.020
NRP1	neuropilin 1	0.020
DBN1	drebrin 1	0.020
CNOT3	CCR4-NOT transcription complex, subunit 3	0.020
ZNF219	zinc finger protein 219	0.020
CRLF3	cytokine receptor-like factor 3	0.020
CSRP2	cysteine and glycine-rich protein 2	0.020
PDZD2	PDZ domain containing 2	0.020
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.020
FOXL1	forkhead box L1	0.020
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.020
MEIS1	Meis homeobox 1	0.020
EPHB2	EPH receptor B2	0.020
SALL1	sal-like 1 (Drosophila)	0.020
KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	0.020
JAM2	junctional adhesion molecule 2	0.020
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.020
DOK5	docking protein 5	0.020
DRD4	dopamine receptor D4	0.020
FAM123A	family with sequence similarity 123A	0.020
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.020
MYH10	myosin, heavy chain 10, non-muscle	0.020
KCTD12	potassium channel tetramerisation domain containing 12	0.020
EFS	embryonal Fyn-associated substrate	0.020
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.020
RUNX3	runt-related transcription factor 3	0.020
LHX5	LIM homeobox 5	0.020
TBX3	T-box 3	0.020
FZD6	frizzled homolog 6 (Drosophila)	0.019
APLP2	amyloid beta (A4) precursor-like protein 2	0.019
PTN	pleiotrophin	0.019
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.019
RPRD2	regulation of nuclear pre-mRNA domain containing 2	0.019
DDIT4	DNA-damage-inducible transcript 4	0.019
BHLHE22	basic helix-loop-helix family, member e22	0.019
KDM5B	lysine (K)-specific demethylase 5B	0.019
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.019
FZD5	frizzled homolog 5 (Drosophila)	0.019	Human Zebrafish
DOCK8	dedicator of cytokinesis 8	0.019
CHD4	chromodomain helicase DNA binding protein 4	0.019
FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	0.019
GIGYF1	GRB10 interacting GYF protein 1	0.019
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.019
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.019
LPL	lipoprotein lipase	0.019
ZFHX4	zinc finger homeobox 4	0.019
CAMK2D	calcium/calmodulin-dependent protein kinase II delta	0.019
TCF12	transcription factor 12	0.019
STRN	striatin, calmodulin binding protein	0.019
HMGA2	high mobility group AT-hook 2	0.019
CAPN1	calpain 1, (mu/I) large subunit	0.019
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.019
SUMF2	sulfatase modifying factor 2	0.019
TLX3	T-cell leukemia homeobox 3	0.019
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.019
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.019
VGLL4	vestigial like 4 (Drosophila)	0.019
ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)	0.019
DUSP7	dual specificity phosphatase 7	0.019
TMSB4X	thymosin beta 4, X-linked	0.019
PTK6	PTK6 protein tyrosine kinase 6	0.019
CGN	cingulin	0.019
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.019
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.019
COL17A1	collagen, type XVII, alpha 1	0.019
EXOC5	exocyst complex component 5	0.019
SH3GL2	SH3-domain GRB2-like 2	0.019
PHF12	PHD finger protein 12	0.019
RBP1	retinol binding protein 1, cellular	0.019
KLF10	Kruppel-like factor 10	0.019
EVPL	envoplakin	0.019
NXN	nucleoredoxin	0.019	Mouse
ARHGAP29	Rho GTPase activating protein 29	0.019
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.019	Mouse
EMX2	empty spiracles homeobox 2	0.019
GATA6	GATA binding protein 6	0.019
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.019
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.019
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.019
CNN3	calponin 3, acidic	0.019
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.019
MN1	meningioma (disrupted in balanced translocation) 1	0.019
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.019
WIPF1	WAS/WASL interacting protein family, member 1	0.019
DCAF7	DDB1 and CUL4 associated factor 7	0.019
NPC2	Niemann-Pick disease, type C2	0.018
WNT7A	wingless-type MMTV integration site family, member 7A	0.018	Human
TMEM173	transmembrane protein 173	0.018
ZBTB20	zinc finger and BTB domain containing 20	0.018
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.018
WT1	Wilms tumor 1	0.018
USP11	ubiquitin specific peptidase 11	0.018
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.018
ARL4D	ADP-ribosylation factor-like 4D	0.018
SS18	synovial sarcoma translocation, chromosome 18	0.018
DSG3	desmoglein 3	0.018
RAB11FIP3	RAB11 family interacting protein 3 (class II)	0.018
MYOD1	myogenic differentiation 1	0.018
TIMP3	TIMP metallopeptidase inhibitor 3	0.018
SH3PXD2A	SH3 and PX domains 2A	0.018
GPSM2	G-protein signaling modulator 2	0.018
SOX2	SRY (sex determining region Y)-box 2	0.018
WDR5	WD repeat domain 5	0.018
PRSS23	protease, serine, 23	0.018
GGN	gametogenetin	0.018
SNCAIP	synuclein, alpha interacting protein	0.018
PLEKHA7	pleckstrin homology domain containing, family A member 7	0.018
COL12A1	collagen, type XII, alpha 1	0.018
GBX2	gastrulation brain homeobox 2	0.018
PENK	proenkephalin	0.018
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.018
C14orf1	chromosome 14 open reading frame 1	0.018
IHH	Indian hedgehog	0.018
ST5	suppression of tumorigenicity 5	0.018
GDNF	glial cell derived neurotrophic factor	0.018
JUND	jun D proto-oncogene	0.018
C17orf63	chromosome 17 open reading frame 63	0.018
MTA1	metastasis associated 1	0.018
ACACA	acetyl-CoA carboxylase alpha	0.018
BCL2L1	BCL2-like 1	0.018
MTA3	metastasis associated 1 family, member 3	0.018
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.018
FRZB	frizzled-related protein	0.018
COL1A2	collagen, type I, alpha 2	0.018
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.018
IRF3	interferon regulatory factor 3	0.018
SALL3	sal-like 3 (Drosophila)	0.018
HES5	hairy and enhancer of split 5 (Drosophila)	0.018
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.018
NPAS1	neuronal PAS domain protein 1	0.018
LBH	limb bud and heart development homolog (mouse)	0.018
HOXD8	homeobox D8	0.018
SIX3	SIX homeobox 3	0.018
MAPK6	mitogen-activated protein kinase 6	0.018
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.018
SOX18	SRY (sex determining region Y)-box 18	0.018	Human
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.018
PCDH8	protocadherin 8	0.018
HCFC1	host cell factor C1 (VP16-accessory protein)	0.018
NEK1	NIMA (never in mitosis gene a)-related kinase 1	0.018
KIRREL	kin of IRRE like (Drosophila)	0.018
TGFA	transforming growth factor, alpha	0.017
FOXJ1	forkhead box J1	0.017
PDX1	pancreatic and duodenal homeobox 1	0.017
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.017
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.017
ZMYM3	zinc finger, MYM-type 3	0.017
TTYH1	tweety homolog 1 (Drosophila)	0.017
COL27A1	collagen, type XXVII, alpha 1	0.017
JAK3	Janus kinase 3	0.017
COL9A3	collagen, type IX, alpha 3	0.017
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.017
PARVA	parvin, alpha	0.017
HOXD1	homeobox D1	0.017
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.017
DLL1	delta-like 1 (Drosophila)	0.017
SFRP5	secreted frizzled-related protein 5	0.017
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.017
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.017
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.017
CHD6	chromodomain helicase DNA binding protein 6	0.017	Human
SH3BP4	SH3-domain binding protein 4	0.017
AIG1	androgen-induced 1	0.017
NOVA1	neuro-oncological ventral antigen 1	0.017
AGRN	agrin	0.017
POMC	proopiomelanocortin	0.017
CHMP7	CHMP family, member 7	0.017
GRHL2	grainyhead-like 2 (Drosophila)	0.017
CRLF1	cytokine receptor-like factor 1	0.017
ZRANB1	zinc finger, RAN-binding domain containing 1	0.017
TYRP1	tyrosinase-related protein 1	0.017
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.017
TCF21	transcription factor 21	0.017
OSR1	odd-skipped related 1 (Drosophila)	0.017
HUNK	hormonally up-regulated Neu-associated kinase	0.017
SULF1	sulfatase 1	0.017
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.017
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.017
KREMEN2	kringle containing transmembrane protein 2	0.017
TTF2	transcription termination factor, RNA polymerase II	0.017
CDH13	cadherin 13, H-cadherin (heart)	0.017
CNOT4	CCR4-NOT transcription complex, subunit 4	0.017
GHR	growth hormone receptor	0.017
E2F3	E2F transcription factor 3	0.017